Senthilkumar Karuppagounder

Research Associate

20062019

Research output per year

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Research Output

Parkin interacting substrate zinc finger protein 746 is a pathological mediator in Parkinson's disease

Brahmachari, S., Lee, S., Kim, S., Yuan, C., Karuppagounder, S., Ge, P., Shi, R., Kim, E. J., Liu, A., Kim, D., Quintin, S., Jiang, H., Kumar, M., Yun, S. P., Kam, T-I., Mao, X., Lee, Y., Swing, D. A., Tessarollo, L., Ko, H. S. & 2 others, Dawson, V. & Dawson, T. M., Aug 1 2019, In : Brain : a journal of neurology. 142, 8, p. 2380-2401 22 p.

Research output: Contribution to journalArticle

  • Transneuronal Propagation of Pathologic α-Synuclein from the Gut to the Brain Models Parkinson's Disease

    Kim, S., Kwon, S. H., Kam, T-I., Panicker, N., Karuppagounder, S., Lee, S., Lee, J. H., Kim, W. R., Kook, M., Foss, C., Shen, C., Lee, H., Kulkarni, S., Pasricha, P. J., Lee, G., Pomper, M. G., Dawson, V., Dawson, T. M. & Ko, H. S., Aug 21 2019, In : Neuron. 103, 4, p. 627-641.e7

    Research output: Contribution to journalArticle

  • Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson's disease

    Yun, S. P., Kam, T-I., Panicker, N., Kim, S., Oh, Y., Park, J. S., Kwon, S. H., Park, Y. J., Karuppagounder, S., Park, H., Kim, S., Oh, N., Kim, N. A., Lee, S., Brahmachari, S., Mao, X., Lee, J. H., Kumar, M., An, D., Kang, S. & 13 others, Lee, Y., Lee, K. C., Na, D. H., Kim, D., Lee, S. H., Roschke, V. V., Liddelow, S. A., Mari, Z., Barres, B. A., Dawson, V., Lee, S., Dawson, T. M. & Ko, H. S., Jul 1 2018, In : Nature Medicine. 24, 7, p. 931-938 8 p.

    Research output: Contribution to journalArticle

  • GBA1 deficiency negatively affects physiological α-synuclein tetramers and related multimers

    Kim, S., Yun, S. P., Lee, S., Umanah, G., Bandaru, V. V. R., Yin, X., Rhee, P., Karuppagounder, S., Kwon, S. H., Lee, H., Mao, X., Kim, D., Pandey, A., Lee, G., Dawson, V., Dawson, T. M. & Ko, H. S., Jan 23 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 4, p. 798-803 6 p.

    Research output: Contribution to journalArticle

  • Poly(ADP-ribose) drives pathologic a-synuclein neurodegeneration in Parkinson’s disease

    Kam, T-I., Mao, X., Park, H., Chou, S. C., Karuppagounder, S., Umanah, G., Yun, S. P., Brahmachari, S., Panicker, N., Chen, R., Andrabi, S. A., Qi, C., Poirier, G. G., Pletnikova, O., Troncoso, J. C., Bekris, L. M., Leverenz, J. B., Pantelyat, A., Ko, H. S., Rosenthal, L. I. S. & 2 others, Dawson, T. M. & Dawson, V., Nov 2 2018, In : Science. 362, 6414, eaat8407.

    Research output: Contribution to journalArticle