Scott Newsome

ASSOCIATE PROFESSOR

20072018
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Research Output 2007 2018

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2018

Distinguishing among multiple sclerosis fallers, near-fallers and non-fallers

Fritz, N. E., Eloyan, A., Baynes, M., Newsome, S. D., Calabresi, P. A. & Zackowski, K. M. Jan 1 2018 In : Multiple Sclerosis and Related Disorders. 19, p. 99-104 6 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Walking
Logistic Models
Rehabilitation

Siponimod versus placebo in secondary progressive multiple sclerosis (EXPAND): a double-blind, randomised, phase 3 study

EXPAND Clinical Investigators Mar 31 2018 In : The Lancet. 391, 10127, p. 1263-1273 11 p.

Research output: Contribution to journalArticle

Chronic Progressive Multiple Sclerosis
Placebos
1-(4-(1-((E)-4-cyclohexyl-3-trifluoromethylbenzyloxyimino)-ethyl)-2-ethylbenzyl)-azetidine-3-carboxylic acid
Bradycardia
Safety

Visual Pathway Measures are Associated with Neuropsychological Function in Multiple Sclerosis

Nguyen, J., Rothman, A., Fitzgerald, K., Whetstone, A., Syc-Mazurek, S., Aquino, J., Balcer, L. J., Frohman, E. M., Frohman, T. C., Crainiceanu, C., Beier, M., Newsome, S. D., Calabresi, P. A. & Saidha, S. May 2 2018 (Accepted/In press) In : Current Eye Research. p. 1-8 8 p.

Research output: Contribution to journalArticle

Visual Pathways
Multiple Sclerosis
Relapsing-Remitting Multiple Sclerosis
Optical Coherence Tomography
Ganglia
2017

A framework of care in multiple sclerosis, part 2: Symptomatic care and beyond

Newsome, S. D., Aliotta, P. J., Bainbridge, J., Bennett, S. E., Cutter, G., Fenton, K., Lublin, F., Northrop, D., Rintell, D., Walker, B. D., Weigel, M., Zackowski, K. & Jones, D. E. 2017 In : International Journal of MS Care. 19, 1, p. 42-56 15 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Urinary Bladder
Quality of Life
Needs Assessment
Continuing Education

Characteristics of morphologic macular abnormalities in neuroimmunology practice

Al-Louzi, O., Sotirchos, E. S., Vidal-Jordana, A., Beh, S. C., Button, J., Ying, H. S., Balcer, L. J., Frohman, E. M., Saidha, S., Calabresi, P. A. & Newsome, S. D. Nov 1 2017 (Accepted/In press) In : Multiple Sclerosis Journal.

Research output: Contribution to journalArticle

Neuromyelitis Optica
Epiretinal Membrane
Optical Coherence Tomography
Multiple Sclerosis
Odds Ratio

Cultivating the multiple sclerosis workforce of the future

DeLuca, G. C. , Buckle, G. , Cortese, I. , Graves, J. S. , Halper, J. , Newsome, S. D. , Sicotte, N. , Ford, C. C. , Aggarwal, S. , Aung, T. , Belliston, S. , Berrios-Morales, I. , Bicchi, M. M. , Daigle, A. , Duval, J. R. , Eleftheriou, E. , Francisco, C. M. , Gonzalez, J. L. , Gyang, T. , Hadden-Young, M. & 12 others Jassam, Y., Konstas, D., McGinley, M., NikHassan, N. H., Nouri, M. N., Orozco-Leon, V. I., Penyak, V., Saada, F., Seay, M., Vlahovic, L., Zhivotenko, V. & on behalf of the FCMSC MS Mentorship Forum Participants 2017 In : International Journal of MS Care. 19, 3, p. 123-130 8 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Mentors
Immune System Diseases
Neurology
Internal Medicine

Disease-modifying therapies modulate retinal atrophy in multiple sclerosis: A retrospective study

Button, J., Al-Louzi, O., Lang, A., Bhargava, P., Newsome, S. D., Frohman, T., Balcer, L. J., Frohman, E. M., Prince, J., Calabresi, P. A. & Saidha, S. Feb 7 2017 In : Neurology. 88, 6, p. 525-532 8 p.

Research output: Contribution to journalArticle

Optical Coherence Tomography
Multiple Sclerosis
Atrophy
Relapsing-Remitting Multiple Sclerosis
Retrospective Studies
Meningeal Neoplasms
Schwann Cells
Autopsy
Neurofibromatosis 1
Neoplasms

Peginterferon beta-1a reduces disability worsening in relapsing-remitting multiple sclerosis: 2-year results from ADVANCE

Newsome, S. D., Kieseier, B. C., Liu, S., You, X., Kinter, E., Hung, S. & Sperling, B. Jan 1 2017 In : Therapeutic Advances in Neurological Disorders. 10, 1, p. 41-50 10 p.

Research output: Contribution to journalArticle

Relapsing-Remitting Multiple Sclerosis
Placebos
Quality of Life
peginterferon beta-1a
Multiple Sclerosis

Retrograde trans-synaptic visual pathway degeneration in multiple sclerosis: A case series

Al-Louzi, O., Button, J., Newsome, S. D., Calabresi, P. A. & Saidha, S. Jun 1 2017 In : Multiple Sclerosis. 23, 7, p. 1035-1039 5 p.

Research output: Contribution to journalArticle

Retrograde Degeneration
Visual Pathways
Ganglia
Multiple Sclerosis
Nervous System

Stiff person syndrome masquerading as multiple sclerosis

Sabatino, J. J. & Newsome, S. D. Jan 15 2017 In : Journal of the Neurological Sciences. 372, p. 297-299 3 p.

Research output: Contribution to journalArticle

Stiff-Person Syndrome
Multiple Sclerosis
Torso
Glutamate Decarboxylase
Spinal Puncture

Two cases of Nicolau syndrome associated with glatiramer acetate

Kimbrough, D. J. & Newsome, S. D. 2017 In : International Journal of MS Care. 19, 3, p. 148-150 3 p.

Research output: Contribution to journalArticle

Injections
Skin
Debridement
Therapeutics
Cosmetics
2016

Adapted resistance training improves strength in eight weeks in individuals with multiple sclerosis

Keller, J. L., Fritz, N., Chiang, C. C., Jiang, A., Thompson, T., Cornet, N., Newsome, S. D., Calabresi, P. A. & Zackowski, K. Jan 29 2016 In : Journal of Visualized Experiments. 2016, 107, e53449

Research output: Contribution to journalArticle

Resistance Training
Multiple Sclerosis
Education
Hip
Direction compound

A framework of care in multiple sclerosis, part 1: Updated disease classification and disease-modifying therapy use in specific circumstances

Newsome, S. D., Aliotta, P. J., Bainbridge, J., Bennett, S. E., Cutter, G., Fenton, K., Lublin, F., Northrop, D., Rintell, D., Walker, B. D., Weigel, M., Zackowski, K. & Jones, D. E. 2016 In : International Journal of MS Care. 18, 6, p. 314-323 10 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Therapeutics
Practice Guidelines
Health Personnel
Magnetic Resonance Imaging

Differentiating neuromyelitis optica from other causes of longitudinally extensive transverse myelitis on spinal magnetic resonance imaging

Pekcevik, Y., Mitchell, C. H., Mealy, M. A., Orman, G., Lee, I. H., Newsome, S. D., Thompson, C. B., Pardo, C. A., Calabresi, P. A., Levy, M. & Izbudak, I. 2016 In : Multiple Sclerosis. 22, 3, p. 302-311 10 p.

Research output: Contribution to journalArticle

Transverse Myelitis
Neuromyelitis Optica
Magnetic Resonance Imaging
Spinal Cord
Brain

Incidence, characterization, and clinical impact analysis of peginterferon beta1a immunogenicity in patients with multiple sclerosis in the ADVANCE trial

White, J. T., Newsome, S. D., Kieseier, B. C., Bermel, R. A., Cui, Y., Seddighzadeh, A., Hung, S., Crossman, M. & Subramanyam, M. Jul 1 2016 In : Therapeutic Advances in Neurological Disorders. 9, 4, p. 239-249 11 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Antibodies
Incidence
Neutralizing Antibodies
Interferons

Management strategies for Flu-Like symptoms and injection-site reactions associated with Peginterferon beta-1a: Obtaining recommendations using the delphi technique

Halper, J., Centonze, D., Newsome, S. D., Huang, D. R., Robertson, C., You, X., Sabatella, G., Evilevitch, V. & Leahy, L. Jul 1 2016 In : International Journal of MS Care. 18, 4, p. 211-218 8 p.

Research output: Contribution to journalArticle

Delphi Technique
Injections
Patient Education
Research Personnel
Therapeutics

Neuromyelitis optica unmasked by a spinal dural arteriovenous fistula

Freund, B., Mowry, E. M., MCR, Levy, M. & Newsome, S. D. Nov 15 2016 In : Journal of Neuroimmunology. 300, p. 18-20 3 p.

Research output: Contribution to journalArticle

Neuromyelitis Optica
Central Nervous System Vascular Malformations
Spinal Cord Diseases

Outer retinal changes following acute optic neuritis

Al-Louzi, O. A., Bhargava, P., Newsome, S. D., Balcer, L. J., Frohman, E. M., Crainiceanu, C., Calabresi, P. A. & Saidha, S. 2016 In : Multiple Sclerosis. 22, 3, p. 362-372 11 p.

Research output: Contribution to journalArticle

Optic Neuritis
Ganglia
Optical Coherence Tomography
Nerve Fibers
Multiple Sclerosis

Stiff Person Syndrome Masquerading as Acute Coronary Syndrome

Sharma, A., Soe, M. H., Singh, J. & Newsome, S. D. Feb 3 2016 In : Journal of the National Medical Association. 108, 3, p. 169-172 4 p.

Research output: Contribution to journalArticle

Stiff-Person Syndrome
Acute Coronary Syndrome
Spasm
Chest Pain
Torso

Subgroup and sensitivity analyses of annualized relapse rate over 2 years in the ADVANCE trial of peginterferon beta-1a in patients with relapsing-remitting multiple sclerosis

Newsome, S. D., Kieseier, B. C., Arnold, D. L., Shang, S., Liu, S., Hung, S. & Sabatella, G. Jun 17 2016 (Accepted/In press) In : Journal of Neurology. p. 1-10 10 p.

Research output: Contribution to journalArticle

Relapsing-Remitting Multiple Sclerosis
Recurrence
Placebos
Demography
Therapeutics
2015

A rare case of hyponatremia from a hypothalamic lesion in a patient with multiple sclerosis

Sabatino, J. J., Werner, J. K. & Newsome, S. D. Apr 1 2015 In : Multiple Sclerosis. 21, 5, p. 662-665 4 p.

Research output: Contribution to journalArticle

Inappropriate ADH Syndrome
Hyponatremia
Multiple Sclerosis
Nervous System
Fatigue

Evaluation and management of longitudinally extensive transverse myelitis: A guide for radiologists

Mirbagheri, S., Eckart Sorte, D., Zamora, C. A., Mossa-Basha, M., Newsome, S. D. & Izbudak, I. Jul 9 2015 (Accepted/In press) In : Clinical Radiology.

Research output: Contribution to journalArticle

Transverse Myelitis
Patient Acuity
Spinal Cord
Demography
Radiologists

Impact of peginterferon beta-1a and disease factors on quality of life in multiple sclerosis

Newsome, S. D., Guo, S., Altincatal, A., Proskorovsky, I., Kinter, E., Phillips, G., You, X. & Sabatella, G. Jul 1 2015 In : Multiple Sclerosis and Related Disorders. 4, 4, p. 350-357 8 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Quality of Life
Placebos
Recurrence
Relapsing-Remitting Multiple Sclerosis

Longitudinally extensive myelopathy in children

Sorte, D. E., Poretti, A., Newsome, S. D., Boltshauser, E., Huisman, T. A. G. M. & Izbudak, I. 2015 In : Pediatric Radiology. 45, 2, p. 244-257 14 p.

Research output: Contribution to journalArticle

Spinal Cord Diseases
Spinal Cord
Transverse Myelitis
Neuromyelitis Optica
Contrast Media

Longitudinal relationships among posturography and gait measures in multiple sclerosis

Fritz, N. E., Newsome, S. D., Eloyan, A., Marasigan, R. E. R., Calabresi, P. A. & Zackowski, K. M. May 19 2015 In : Neurology. 84, 20, p. 2048-2056 9 p.

Research output: Contribution to journalArticle

Gait
Multiple Sclerosis
Walking
Foot
Relapsing-Remitting Multiple Sclerosis
Progressive Multifocal Leukoencephalopathy
Molecular Pathology
Routine Diagnostic Tests
Multiple Sclerosis
JC Virus

Optical coherence tomography reflects brain atrophy in multiple sclerosis: A four-year study

Saidha, S., Al-Louzi, O., Ratchford, J. N., Bhargava, P., Oh, J., Newsome, S. D., Prince, J. L., Pham, D., Roy, S., Van Zijl, P., Balcer, L. J., Frohman, E. M., Reich, D. S., Crainiceanu, C. & Calabresi, P. A. Nov 1 2015 In : Annals of Neurology. 78, 5, p. 801-813 13 p.

Research output: Contribution to journalArticle

Optical Coherence Tomography
Multiple Sclerosis
Atrophy
Ganglia
Brain

Patient Management Problem

Venkatesan, A. & Newsome, S. D. Dec 1 2015 In : CONTINUUM Lifelong Learning in Neurology. 21, 6 Neuroinfectious Disease

Research output: Contribution to journalArticle

Herpes Zoster
Neurology
Seizures
Multiple Sclerosis
Walking
Lower Extremity
Leg
Walking Speed

Relationships between quantitative spinal cord MRI and retinal layers in multiple sclerosis

Oh, J., Sotirchos, E. S., Saidha, S., Whetstone, A., Chen, M., Newsome, S. D., Zackowski, K., Balcer, L. J., Frohman, E., Prince, J., Diener-West, M., Reich, D. S. & Calabresi, P. A. Feb 17 2015 In : Neurology. 84, 7, p. 720-728 9 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Spinal Cord
Nerve Fibers
Visual Acuity
Atrophy

The impact of dynamic balance measures on walking performance in multiple sclerosis

Fritz, N. E., Marasigan, R. E. R., Calabresi, P. A., Newsome, S. D. & Zackowski, K. M. Jan 19 2015 In : Neurorehabilitation and Neural Repair. 29, 1, p. 62-69 8 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Walking
Hip
Foot
Hand Strength
2014

Balancing the risks and benefits of therapy

Newsome, S. D. 2014 In : International Journal of MS Care. 16, p. 7-13 7 p.

Research output: Contribution to journalArticle

Therapeutics

Clinical reasoning: A 68-year-old man with a first presentation of status epilepticus

Schneider, L., Probasco, J. C. & Newsome, S. D. Apr 8 2014 In : Neurology. 82, 14

Research output: Contribution to journalArticle

Clinical Reasoning
Risk Factors

Daclizumab-induced adverse events in multiple organ systems in multiple sclerosis

Oh, J., Saidha, S., Cortese, I., Ohayon, J., Bielekova, B., Calabresi, P. A. & Newsome, S. D. Mar 18 2014 In : Neurology. 82, 11, p. 984-988 5 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Breast
Exanthema
Research Ethics Committees
daclizumab

Progressive multifocal leukoencephalopathy associated with brentuximab vedotin therapy: A report of 5 cases from the Southern Network on Adverse Reactions (SONAR) project

Carson, K. R., Newsome, S. D., Kim, E. J., Wagner-Johnston, N. D., Von Geldern, G., Moskowitz, C. H., Moskowitz, A. J., Rook, A. H., Jalan, P., Loren, A. W., Landsburg, D., Coyne, T., Tsai, D., Raisch, D. W., Norris, L. B., Bookstaver, P. B., Sartor, O. & Bennett, C. L. Aug 15 2014 In : Cancer. 120, 16, p. 2464-2471 8 p.

Research output: Contribution to journalArticle

Progressive Multifocal Leukoencephalopathy
Therapeutics
JC Virus
cAC10-vcMMAE
Immune Reconstitution Inflammatory Syndrome
Immunoconjugates
Progressive Multifocal Leukoencephalopathy
Vincristine
Prednisone
Non-Hodgkin's Lymphoma
2013

Active MS is associated with accelerated retinal ganglion cell/inner plexiform layer thinning

Ratchford, J. N., Saidha, S., Sotirchos, E. S., Oh, J. A., Seigo, M. A., Eckstein, C., Durbin, M. K., Oakley, J. D., Meyer, S. A., Conger, A., Frohman, T. C., Newsome, S. D., Balcer, L. J., Frohman, E. M. & Calabresi, P. A. Jan 1 2013 In : Neurology. 80, 1, p. 47-54 8 p.

Research output: Contribution to journalArticle

Retinal Ganglion Cells
Multiple Sclerosis
Ganglia
Optical Coherence Tomography
Gadolinium

In vivo identification of morphologic retinal abnormalities in neuromyelitis optica

Sotirchos, E. S., Saidha, S., Byraiah, G., Mealy, M. A., Ibrahim, M. A., Sepah, Y. J., Newsome, S. D., Ratchford, J. N., Frohman, E. M., Balcer, L. J., Crainiceanu, C. M., Nguyen, Q. D., Levy, M. & Calabresi, P. A. Apr 9 2013 In : Neurology. 80, 15, p. 1406-1414 9 p.

Research output: Contribution to journalArticle

Neuromyelitis Optica
Optic Neuritis
Macular Edema
Nerve Fibers
Optical Coherence Tomography

Multiparametric MRI correlates of sensorimotor function in the spinal cord in multiple sclerosis

Oh, J., Zackowski, K., Chen, M., Newsome, S., Saidha, S., Smith, S. A., Diener-West, M., Prince, J., Jones, C. K., Van Zijl, P. C. M., Calabresi, P. A. & Reich, D. S. 2013 In : Multiple Sclerosis. 19, 4, p. 427-435 9 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Spinal Cord
Magnetic Resonance Imaging
Anisotropy
Chronic Progressive Multiple Sclerosis

Relationships between retinal axonal and neuronal measures and global central nervous system pathology in multiple sclerosis

Saidha, S., Sotirchos, E. S., Oh, J., Syc, S. B., Seigo, M. A., Shiee, N., Eckstein, C., Durbin, M. K., Oakley, J. D., Meyer, S. A., Frohman, T. C., Newsome, S., Ratchford, J. N., Balcer, L. J., Pham, D. L., Crainiceanu, C. M., Frohman, E. M., Reich, D. S. & Calabresi, P. A. Jan 2013 In : Archives of Neurology. 70, 1, p. 34-43 10 p.

Research output: Contribution to journalArticle

Optical Coherence Tomography
Multiple Sclerosis
Central Nervous System
Pathology
Brain

Tract-specific quantitative MRI better correlates with disability than conventional MRI in multiple sclerosis

Harrison, D. M., Shiee, N., Bazin, P. L., Newsome, S. D., Ratchford, J. N., Pham, D., Calabresi, P. A. & Reich, D. S. Feb 2013 In : Journal of Neurology. 260, 2, p. 397-406 10 p.

Research output: Contribution to journalArticle

Diffusion Tensor Imaging
Multiple Sclerosis
Atrophy
Radiation
Corpus Callosum
2012

Clinical/scientific notes

Von Geldern, G., Pardo, C. A., Calabresi, P. A. & Newsome, S. D. Nov 13 2012 In : Neurology. 79, 20, p. 2075-2077 3 p.

Research output: Contribution to journalArticle

Immune Reconstitution Inflammatory Syndrome
Immunoconjugates
CD31 Antigens
Leukoencephalopathies
Cutaneous T-Cell Lymphoma

Development of protein biomarkers in cerebrospinal fluid for secondary progressive multiple sclerosis using selected reaction monitoring mass spectrometry (SRM-MS)

Jia, Y., Wu, T., Jelinek, C. A., Bielekova, B., Chang, L., Newsome, S., Gnanapavan, S., Giovannoni, G., Chen, D., Calabresi, P. A., Nath, A. & Cotter, R. J. 2012 In : Clinical Proteomics. 9, 1, 027599

Research output: Contribution to journalArticle

Chronic Progressive Multiple Sclerosis
Cerebrospinal fluid
Biomarkers
Mass spectrometry
Cerebrospinal Fluid

In vivo assessment of retinal neuronal layers in multiple sclerosis with manual and automated optical coherence tomography segmentation techniques

Seigo, M. A., Sotirchos, E. S., Newsome, S., Babiarz, A., Eckstein, C., Ford, ET., Oakley, J. D., Syc, S. B., Frohman, T. C., Ratchford, J. N., Balcer, L. J., Frohman, E. M., Calabresi, P. A. & Saidha, S. Oct 2012 In : Journal of Neurology. 259, 10, p. 2119-2130 12 p.

Research output: Contribution to journalArticle

Optical Coherence Tomography
Multiple Sclerosis
Equipment and Supplies
Ganglia

Low serum vitamin D levels and recurrent inflammatory spinal cord disease

Mealy, M. A., Newsome, S., Greenberg, B. M., Wingerchuk, D., Calabresi, P. & Levy, M. Mar 2012 In : Archives of Neurology. 69, 3, p. 352-356 5 p.

Research output: Contribution to journalArticle

Spinal Cord Diseases
Vitamin D
Serum
Multiple Sclerosis
Transverse Myelitis

Microcystic macular oedema, Thickness of the inner nuclear layer of the retina, and disease characteristics in multiple sclerosis: A retrospective study

Saidha, S., Sotirchos, E. S., Ibrahim, M. A., Crainiceanu, C. M., Gelfand, J. M., Sepah, Y. J., Ratchford, J. N., Oh, J., Seigo, M. A., Newsome, S. D., Balcer, L. J., Frohman, E. M., Green, A. J., Nguyen, Q. D. & Calabresi, P. A. Nov 2012 In : The Lancet Neurology. 11, 11, p. 963-972 10 p.

Research output: Contribution to journalArticle

Macular Edema
Multiple Sclerosis
Retina
Retrospective Studies
Optical Coherence Tomography

Optical coherence tomography segmentation reveals ganglion cell layer pathology after optic neuritis

Syc, S. B., Saidha, S., Newsome, S. D., Ratchford, J. N., Levy, M., Ford, ET., Crainiceanu, C. M., Durbin, M. K., Oakley, J. D., Meyer, S. A., Frohman, E. M. & Calabresi, P. A. 2012 In : Brain. 135, 2, p. 521-533 13 p.

Research output: Contribution to journalArticle

Optic Neuritis
Optical Coherence Tomography
Ganglia
Multiple Sclerosis
Pathology

Revisiting brain atrophy and its relationship to disability in multiple sclerosis.

Shiee, N., Bazin, P. L., Zackowski, K. M., Farrell, S. K., Harrison, D. M., Newsome, S. D., Ratchford, J. N., Caffo, B. S., Calabresi, P. A., Pham, D. L. & Reich, D. S. 2012 In : PLoS One. 7, 5, e37049

Research output: Contribution to journalArticle

sclerosis
Biomarkers
atrophy
Multiple Sclerosis
Atrophy
2011

Diffusion tensor imaging of the optic nerve in multiple sclerosis: Association with retinal damage and visual disability

Smith, S. A., Williams, Z. R., Ratchford, J. N., Newsome, S. D., Farrell, S. K., Farrell, J. A. D., Gifford, A., Miller, N. R., Van Zijl, P. C. M., Calabresi, P. A. & Reich, D. S. Oct 2011 In : American Journal of Neuroradiology. 32, 9, p. 1662-1668 7 p.

Research output: Contribution to journalArticle

Diffusion Tensor Imaging
Optic Nerve
Multiple Sclerosis