Scott Kominsky

Associate Professor

19982018

Research output per year

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Research Output

2018

CITED2 attenuates macrophage recruitment concordant with the downregulation of CCL20 in breast cancer cells

Jayaraman, S., Doucet, M. & Kominsky, S., Jan 1 2018, In : Oncology Letters. 15, 1, p. 871-878 8 p.

Research output: Contribution to journalArticle

Concepts and surgical treatment of metastatic bone disease

Weber, K. & Kominsky, S., Jan 1 2018, Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism. wiley, p. 816-821 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Label-free Raman spectroscopy provides early determination and precise localization of breast cancer-colonized bone alterations

Zhang, C., Winnard, P. T., Dasari, S., Kominsky, S., Doucet, M., Jayaraman, S., Raman, V. & Barman, I., Jan 1 2018, In : Chemical Science. 9, 3, p. 743-753 11 p.

Research output: Contribution to journalArticle

2017

Down-regulation of CITED2 attenuates breast tumor growth, vessel formation and TGF-β-induced expression of VEGFA

Jayaraman, S., Doucet, M. & Kominsky, S., 2017, In : Oncotarget. 8, 4, p. 6169-6178 10 p.

Research output: Contribution to journalArticle

2016

CCL20/CCR6 Signaling Regulates Bone Mass Accrual in Mice

Doucet, M., Jayaraman, S., Swenson, E., Tusing, B., Weber, K. L. & Kominsky, S., Jul 1 2016, In : Journal of Bone and Mineral Research. 31, 7, p. 1381-1390 10 p.

Research output: Contribution to journalArticle

CITED2 Modulates Breast Cancer Metastatic Ability through Effects on IKKα

Jayaraman, S., Doucet, M., Lau, W. M. & Kominsky, S., Aug 1 2016, In : Molecular Cancer Research. 14, 8, p. 730-739 10 p.

Research output: Contribution to journalArticle

2014

The Notch pathway inhibits TGFβ signaling in breast cancer through HEYL-mediated crosstalk

Han, L., Diehl, A., Nguyen, N. K., Korangath, P., Teo, W., Cho, S., Kominsky, S., Huso, D. L., Feigenbaum, L., Rein, A., Argani, P., Landberg, G., Gessler, M. & Sukumar, S., Nov 15 2014, In : Cancer Research. 74, 22, p. 6509-6518 10 p.

Research output: Contribution to journalArticle

2013

CITED2 modulates estrogen receptor transcriptional activity in breast cancer cells

Lau, W. M., Doucet, M., Huang, D., Weber, K. L. & Kominsky, S. L., Jul 26 2013, In : Biochemical and Biophysical Research Communications. 437, 2, p. 261-266 6 p.

Research output: Contribution to journalArticle

Concepts and Surgical Treatment of Metastatic Bone Disease

Weber, K. & Kominsky, S., Jul 19 2013, Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism: Eighth Edition. Wiley Blackwell, p. 760-765 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Enpp1: A Potential Facilitator of Breast Cancer Bone Metastasis

Lau, W. M., Doucet, M., Stadel, R., Huang, D., Weber, K. L. & Kominsky, S. L., Jul 5 2013, In : PloS one. 8, 7, e66752.

Research output: Contribution to journalArticle

2012

MIP-1δ activates NFATc1 and enhances osteoclastogenesis: Involvement of both PLCγ2 and NFκB signaling

Weber, K. L., Doucet, M., Shaner, A., Hsu, N., Huang, D., Fogel, J. & Kominsky, S. L., Jul 9 2012, In : PloS one. 7, 7, e40799.

Research output: Contribution to journalArticle

2011

Breast cancer: Preclinical and clinical evaluation of intraductally administered agents in early breast cancer

Stearns, V., Mori, T., Jacobs, L. K., Khouri, N. F., Gabrielson, E., Yoshida, T., Kominsky, S. L., Huso, D. L., Jeter, S., Powers, P., Tarpinian, K., Brown, R. J., Lange, J. R., Rudek, M. A., Zhang, Z., Tsangaris, T. N. & Sukumar, S., Oct 26 2011, In : Science translational medicine. 3, 106, 106ra108.

Research output: Contribution to journalArticle

2010

Identification of prospective factors promoting osteotropism in breast cancer: A potential role for CITED2

Lau, W. M., Weber, K. L., Doucet, M., Chou, Y. T., Brady, K., Kowalski, J., Tsai, H. L., Yang, J. & Kominsky, S. L., Feb 15 2010, In : International Journal of Cancer. 126, 4, p. 876-884 9 p.

Research output: Contribution to journalArticle

2009

Orthopedic Treatment of Metastatic Bone Disease

Weber, K. & Kominsky, S., Dec 23 2009, Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism: Seventh Edition. John Wiley & Sons, Inc., p. 407-410 4 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2008

Macrophage inflammatory protein-1δ: A novel osteoclast stimulating factor secreted by renal cell carcinoma bone metastasis

Kominsky, S. L., Abdelmagid, S. M., Doucet, M., Brady, K. & Weber, K. L., Mar 1 2008, In : Cancer Research. 68, 5, p. 1261-1266 6 p.

Research output: Contribution to journalArticle

MMP-13 is over-expressed in renal cell carcinoma bone metastasis and is induced by TGF-β1

Kominsky, S. L., Doucet, M., Thorpe, M. & Weber, K. L., Dec 1 2008, In : Clinical and Experimental Metastasis. 25, 8, p. 865-870 6 p.

Research output: Contribution to journalArticle

2007

Clostridium perfringens enterotoxin as a novel-targeted therapeutic for brain metastasis

Kominsky, S. L., Tyler, B., Sosnowski, J., Brady, K., Doucet, M., Nell, D., Smedley, J. G., McClane, B., Brem, H. & Sukumar, S., Sep 1 2007, In : Cancer Research. 67, 17, p. 7977-7982 6 p.

Research output: Contribution to journalArticle

Renal cell carcinoma bone metastasis-elucidating the molecular targets

Weber, K., Doucet, M. & Kominsky, S., Dec 1 2007, In : Cancer and Metastasis Reviews. 26, 3-4, p. 691-704 14 p.

Research output: Contribution to journalReview article

TGF-β promotes the establishment of renal cell carcinoma bone metastasis

Kominsky, S. L., Doucet, M., Brady, K. & Weber, K. L., Jan 1 2007, In : Journal of Bone and Mineral Research. 22, 1, p. 37-44 8 p.

Research output: Contribution to journalArticle

2006

A "bone" fide predictor of metastasis? Predicting breast cancer metastasis to bone

Kominsky, S. L. & Davidson, N. E., May 20 2006, In : Journal of Clinical Oncology. 24, 15, p. 2227-2229 3 p.

Research output: Contribution to journalEditorial

Claudins: Emerging targets for cancer therapy

Kominsky, S. L., Aug 1 2006, In : Expert reviews in molecular medicine. 8, 18, p. 1-11 11 p.

Research output: Contribution to journalArticle

Ductal access for prevention and therapy of mammary tumors

Murata, S., Kominsky, S. L., Vali, M., Zhang, Z., Garrett-Mayer, E., Korz, D., Huso, D., Baker, S. D., Barber, J., Jaffee, E., Reilly, R. T. & Sukumar, S., Jan 15 2006, In : Cancer Research. 66, 2, p. 638-645 8 p.

Research output: Contribution to journalArticle

Targeting early stage DCIS breast cancer directly in the ducts with intraductal chemotherapy

Sukumar, S., Murata, S., Kominsky, S., Vali, M., Zhang, Z., Garrett-Mayer, E., Korz, D., Huso, D., Baker, S. D., Barber, J., Jaffee, E. & Reilly, R. T., Mar 1 2006, In : Cancer Biology and Therapy. 5, 3, p. 249-250 2 p.

Research output: Contribution to journalComment/debate

2005

Twist overexpression induces in vivo angiogenesis and correlates with chromosomal instability in breast cancer

Mironchik, Y., Winnard, P. T., Vesuna, F., Kato, Y., Wildes, F., Pathak, A. P., Kominsky, S., Artemov, D., Bhujwalla, Z., Van Diest, P., Burger, H., Glackin, C. & Raman, V., Dec 1 2005, In : Cancer Research. 65, 23, p. 10801-10809 9 p.

Research output: Contribution to journalArticle

2004

Clostridium perfringens Enterotoxin Elicits Rapid and Specific Cytolysis of Breast Carcinoma Cells Mediated through Tight Junction Proteins Claudin 3 and 4

Kominsky, S. L., Vali, M., Korz, D., Gabig, T. G., Weitzman, S. A., Argani, P. & Sukumar, S., May 2004, In : American Journal of Pathology. 164, 5, p. 1627-1633 7 p.

Research output: Contribution to journalArticle

Very High Frequency of Hypermethylated Genes in Breast Cancer Metastasis to the Bone, Brain, and Lung

Mehrotra, J., Vali, M., McVeigh, M., Kominsky, S. L., Fackler, M. J., Lahti-Domenici, J., Polyak, K., Sacchi, N., Garrett-Mayer, E., Argani, P. & Sukumar, S., May 1 2004, In : Clinical Cancer Research. 10, 9, p. 3104-3109 6 p.

Research output: Contribution to journalArticle

2003

Loss of the tight junction protein claudin-7 correlates with histological grade in both ductal carcinoma in situ and invasive ductal carcinoma of the breast

Kominsky, S. L., Argani, P., Korz, D., Evron, E., Raman, V., Garrett, E., Rein, A., Sauter, G., Kallioniemi, O. P. & Sukumar, S., Apr 3 2003, In : Oncogene. 22, 13, p. 2021-2033 13 p.

Research output: Contribution to journalArticle

2001

Superantigen enhanced protection against a weak tumor-specific melanoma antigen: Implications for prophylactic vaccination against cancer

Kominsky, S. L., Torres, B. A., Hobeika, A. C., Lake, F. A. & Johnson, H. M., Dec 15 2001, In : International Journal of Cancer. 94, 6, p. 834-841 8 p.

Research output: Contribution to journalArticle

Superantigens: The good, the bad, and the ugly

Torres, B. A., Kominsky, S., Perrin, G. Q., Hobeika, A. C. & Johnson, H. M., Jun 15 2001, In : Experimental Biology and Medicine. 226, 3, p. 164-176 13 p.

Research output: Contribution to journalShort survey

2000

Down-regulation of neu/HER-2 by interferon-γ in prostate cancer cells

Kominsky, S. L., Hobeika, A. C., Lake, F. A., Torres, B. A. & Johnson, H. M., Jul 15 2000, In : Cancer Research. 60, 14, p. 3904-3908 5 p.

Research output: Contribution to journalArticle

Inhibition of the glioblastoma cell cycle by type I IFNs occurs at both the G1 and S phases and correlates with the upregulation of p21(WAF1/CIP1)

Tanabe, T., Kominsky, S. L., Subramaniam, P. S., Johnson, H. M. & Torres, B. A., Nov 21 2000, In : Journal of neuro-oncology. 48, 3, p. 225-232 8 p.

Research output: Contribution to journalArticle

Inhibitory effects of IFN-γ and acyclovir on the glioblastoma cell cycle

Kominsky, S. L., Subramaniam, P. S., Johnson, H. M. & Torres, B. A., Jul 10 2000, In : Journal of Interferon and Cytokine Research. 20, 5, p. 463-469 7 p.

Research output: Contribution to journalArticle

1998

IFNγ inhibition of cell growth in glioblastomas correlates with increased levels of the cyclin dependent kinase inhibitor p21(WAF1/CIP1)

Kominsky, S., Johnson, H. M., Bryan, G., Tanabe, T., Hobeika, A. C., Subramaniam, P. S. & Torres, B., Dec 10 1998, In : Oncogene. 17, 23, p. 2973-2979 7 p.

Research output: Contribution to journalArticle

Open Access