Saurav Brahmachari


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Parkinson Disease Medicine & Life Sciences
Dopaminergic Neurons Medicine & Life Sciences
Sodium Benzoate Medicine & Life Sciences
Cinnamomum zeylanicum Medicine & Life Sciences
Myelin Basic Protein Medicine & Life Sciences
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Medicine & Life Sciences
Proto-Oncogene Proteins p21(ras) Medicine & Life Sciences
Substantia Nigra Medicine & Life Sciences

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Research Output 2006 2017

C-Abl and Parkinson's Disease: Mechanisms and Therapeutic Potential

Brahmachari, S., Karuppagounder, S. S., Ge, P., Lee, S., Dawson, V. L., Dawson, T. M. & Ko, H. S., 2017, In : Journal of Parkinson's Disease. 7, 4, p. 589-601 13 p.

Research output: Contribution to journalReview article

Parkinson Disease
Oxidative Stress
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Precursor Cell Lymphoblastic Leukemia-Lymphoma

PINK1 Primes Parkin-Mediated Ubiquitination of PARIS in Dopaminergic Neuronal Survival

Lee, Y. , Stevens, D. A. , Kang, S. U. , Jiang, H. , Lee, Y. I. , Ko, H. S. , Scarffe, L. A. , Umanah, G. E. , Kang, H. , Ham, S. , Kam, T. I. , Allen, K. , Brahmachari, S. , Kim, J. W. , Neifert, S. , Yun, S. P. , Fiesel, F. C. , Springer, W. , Dawson, V. L. , Shin, J. H. & 1 others Dawson, T. M., Jan 24 2017, In : Cell Reports. 18, 4, p. 918-932 15 p.

Research output: Contribution to journalArticle

Dopaminergic Neurons
Substantia Nigra

Activation of tyrosine kinase c-Abl contributes to α-synuclein-induced neurodegeneration

Brahmachari, S., Ge, P., Lee, S. H., Kim, D., Karuppagounder, S. S., Kumar, M., Mao, X., Shin, J. H., Lee, Y., Pletnikova, O., Troncoso, J. C., Dawson, V. L., Dawson, T. M. & Ko, H. S., Aug 1 2016, In : Journal of Clinical Investigation. 126, 8, p. 2970-2988 19 p.

Research output: Contribution to journalArticle

Protein-Tyrosine Kinases
Parkinson Disease
abl Genes

Pathological α-synuclein transmission initiated by binding lymphocyte-activation gene 3

Mao, X. , Ou, M. T. , Karuppagounder, S. S. , Kam, T. I. , Yin, X. , Xiong, Y. , Ge, P. , Umanah, G. E. , Brahmachari, S. , Shin, J. H. , Kang, H. C. , Zhang, J. , Xu, J. , Chen, R. , Park, H. , Andrabi, S. A. , Kang, S. U. , Gonçalves, R. A. , Liang, Y. , Zhang, S. & 12 others Qi, C., Lam, S., Keiler, J. A., Tyson, J., Kim, D., Panicker, N., Yun, S. P., Workman, C. J., Vignali, D. A. A., Dawson, V. L., Ko, H. S. & Dawson, T. M., Sep 30 2016, In : Science. 353, 6307, aah3374

Research output: Contribution to journalArticle

Lymphocyte Activation
Parkinson Disease

Cinnamon and its metabolite sodium benzoate attenuate the activation of p21rac and protect memory and learning in an animal model of Alzheimer's disease

Modi, K. K., Roy, A., Brahmachari, S., Rangasamy, S. B. & Pahan, K., Jun 23 2015, In : PLoS One. 10, 6, e0130398

Research output: Contribution to journalArticle

Sodium Benzoate
Cinnamomum zeylanicum
sodium benzoate
Alzheimer disease