Sangwoo Cho

Research Associate

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Fingerprint Dive into the research topics where Sangwoo Cho is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 4 Similar Profiles
Natural Killer Cell Receptors Medicine & Life Sciences
Proteolysis Medicine & Life Sciences
Proteins Medicine & Life Sciences
T-cells Chemical Compounds
Organoplatinum Compounds Medicine & Life Sciences
T-Lymphocytes Medicine & Life Sciences
Antineoplastic Agents Medicine & Life Sciences
Peptide Hydrolases Medicine & Life Sciences

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Research Output 2000 2019

Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release

Cho, S., Baker, R. P., Ji, M. & Urban, S., Oct 1 2019, In : Nature Structural and Molecular Biology. 26, 10, p. 910-918 9 p.

Research output: Contribution to journalArticle

Catalytic Domain

Crystal Structures and Inhibition Kinetics Reveal a Two-Stage Catalytic Mechanism with Drug Design Implications for Rhomboid Proteolysis

Cho, S., Dickey, S. W. & Urban, S., Feb 4 2016, In : Molecular Cell. 61, 3, p. 329-340 12 p.

Research output: Contribution to journalArticle

Drug Design
Peptide Hydrolases

Proteolysis inside the membrane is a rate-governed reaction not driven by Substrate Affinity

Dickey, S. W., Baker, R., Cho, S. & Urban, S., Dec 5 2013, In : Cell. 155, 6, p. 1270-1281 12 p.

Research output: Contribution to journalArticle

Reaction rates
Peptide Hydrolases
Membrane Proteins

Crystal structure of Staphylococcal Enterotoxin G (SEG) in complex with a mouse T-cell receptor β chain

Fernández, M. M., Cho, S., De Marzi, M. C., Kerzic, M. C., Robinson, H., Mariuzza, R. A. & Malchiodi, E. L., Jan 14 2011, In : Journal of Biological Chemistry. 286, 2, p. 1189-1195 7 p.

Research output: Contribution to journalArticle

T-Cell Antigen Receptor
Crystal structure
Bearings (structural)
Purpura Fulminans

Assessing energetic contributions to binding from a disordered region in a protein-protein interaction

Cho, S., Swaminathan, C. P., Bonsor, D. A., Kerzic, M. C., Guan, R., Yang, J., Kieke, M. C., Andersen, P. S., Kranz, D. M., Mariuzza, R. A. & Sundberg, E. J., Nov 2 2010, In : Biochemistry. 49, 43, p. 9256-9268 13 p.

Research output: Contribution to journalArticle

Protein Binding
Carrier Proteins
Hot Temperature
Specific heat