Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 5 Similar Profiles
Enzymes Medicine & Life Sciences
Proteins Medicine & Life Sciences
Mutation Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Hydrolases Medicine & Life Sciences
Substrates Chemical Compounds
Pyrophosphatases Medicine & Life Sciences
Phosphotransferases Medicine & Life Sciences

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Research Output 2001 2017

A Tunable Brake for HECT Ubiquitin Ligases

Chen, Z., Jiang, H., Xu, W., Li, X., Dempsey, D. R., Zhang, X., Devreotes, P., Wolberger, C., Amzel, L. M., Gabelli, S. B. & Cole, P. A. May 4 2017 In : Molecular Cell. 66, 3, p. 345-357.e6

Research output: Research - peer-reviewArticle

Ligases
Ubiquitin
Neoplasms
Ubiquitin-Protein Ligases
Immune System Diseases
Hydrogen
Communication
Peptides
Research
Neoplasms

Identification of allosteric binding sites for PI3Kα oncogenic mutant specific inhibitor design

Miller, M. S., Maheshwari, S., McRobb, F. M., Kinzler, K. W., Amzel, L. M., Vogelstein, B. & Gabelli, S. B. Feb 15 2017 In : Bioorganic and Medicinal Chemistry. 25, 4, p. 1481-1486 6 p.

Research output: Research - peer-reviewArticle

Phosphatidylinositol 3-Kinase
Allosteric Site
Binding Sites
X Ray Crystallography
Libraries

Kinetic and structural analyses reveal residues in phosphoinositide 3-kinase α that are critical for catalysis and substrate recognition

Maheshwari, S., Miller, M. S., O’Meally, R., Cole, R. N., Amzel, L. M. & Gabelli, S. B. 2017 In : Journal of Biological Chemistry. 292, 33, p. 13541-13550 10 p.

Research output: Research - peer-reviewArticle

Phosphatidylinositols
Catalysis
Phosphotransferases
Kinetics
Substrates
Casein Kinase II
Phosphorylation
Lipids
Proteins
PDZ Domains