Sandra B Gabelli

Associate Professor

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  • 5 Similar Profiles
Enzymes Medicine & Life Sciences
Adenosine Diphosphate Ribose Medicine & Life Sciences
Mutation Medicine & Life Sciences
Pyrophosphatases Medicine & Life Sciences
Guanosine Diphosphate Mannose Medicine & Life Sciences
Hydrolases Medicine & Life Sciences
Phosphatidylinositol 3-Kinases Medicine & Life Sciences
Phosphatidylinositol 3-Kinase Medicine & Life Sciences

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Research Output 2001 2019

Ca 2+ -dependent regulation of sodium channels Na V 1.4 and Na V 1.5 is controlled by the post-IQ motif

Yoder, J. B., Ben-Johny, M., Farinelli, F., Srinivasan, L., Shoemaker, S. R., Tomaselli, G. F., Gabelli, S. B. & Amzel, M. L., Dec 1 2019, In : Nature communications. 10, 1, 1514.

Research output: Contribution to journalArticle

Open Access
Sodium Channels
Cardiac Arrhythmias

Getting the most out of your crystals: Data collection at the new high-flux, Microfocus MX beamlines at NSLS-II

Miller, M. S., Maheshwari, S., Shi, W., Gao, Y., Chu, N., Soares, A. S., Cole, P. A., Amzel, M. L., Fuchs, M. R., Jakoncic, J. & Gabelli, S. B., Jan 30 2019, In : Molecules. 496.

Research output: Contribution to journalArticle

Cytidine Diphosphate

Structural analyses of NudT16–ADP-ribose complexes direct rational design of mutants with improved processing of poly(ADP-ribosyl)ated proteins

Thirawatananond, P., McPherson, R. L., Malhi, J., Nathan, S., Lambrecht, M. J., Brichacek, M., Hergenrother, P. J., Leung, A. K. L. & Gabelli, S. B., Dec 1 2019, In : Scientific reports. 9, 1, 5940.

Research output: Contribution to journalArticle

Open Access
Adenosine Diphosphate Ribose
Poly Adenosine Diphosphate Ribose
ADP-ribosylarginine hydrolase

Structural Determinants of Isoform Selectivity in PI3K Inhibitors

Miller, M. S., Thompson, P. E. & Gabelli, S. B., Feb 26 2019, In : Biomolecules. 9, 3

Research output: Contribution to journalReview article

Open Access
Phosphatidylinositol 3-Kinases
Protein Isoforms
Class I Phosphatidylinositol 3-Kinases
Pharmaceutical Chemistry
Immune System Diseases

Akt Kinase Activation Mechanisms Revealed Using Protein Semisynthesis

Chu, N., Salguero, A. L., Liu, A. Z., Chen, Z., Dempsey, D. R., Ficarro, S. B., Alexander, W. M., Marto, J. A., Li, Y., Amzel, M. L., Gabelli, S. B. & Cole, P. A., Aug 9 2018, In : Cell. 174, 4, p. 897-907.e14

Research output: Contribution to journalArticle

Chemical activation
Structural Models