Samuel R Denmeade

Professor

1985 …2018
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Research Output 1985 2018

Muscadine grape skin extract (MPX) in men with biochemically recurrent prostate cancer: A randomized, multicenter, placebo-controlled clinical trial

Paller, C. J. , Zhou, X. C. , Heath, E. I. , Taplin, M. E. , Mayer, T. , Stein, M. N. , Bubley, G. J. , Pili, R. , Hudson, T. , Kakarla, R. , Abbas, M. M. , Anders, N. M. , Dowling, D. , King, S. , Bruns, A. B. , Wagner, W. D. , Drake, C. G. , Antonarakis, E. S. , Eisenberger, M. A. , Denmeade, S. R. & 3 others Rudek, M. A., Rosner, G. L. & Carducci, M. A. Jan 15 2018 In : Clinical Cancer Research. 24, 2, p. 306-315 10 p.

Research output: Contribution to journalArticle

Controlled Clinical Trials
Vitis
Prostatic Neoplasms
Placebos
Skin

PSA-alpha-2-macroglobulin complex is enzymatically active in the serum of patients with advanced prostate cancer and can degrade circulating peptide hormones

Kostova, M. B., Brennen, W. N., Lopez, D., Anthony, L., Wang, H., Platz, E. & Denmeade, S. R. Jan 1 2018 (Accepted/In press) In : Prostate.

Research output: Contribution to journalArticle

alpha-Macroglobulins
Peptide Hormones
Prostate-Specific Antigen
Prostatic Neoplasms
Serum

PSA-selective activation of cytotoxic human serine proteases within the tumor microenvironment as a therapeutic strategy to target prostate cancer

Rogers, O. C., Anthony, L., Rosen, D. M., Brennen, W. N. & Denmeade, S. R. Apr 27 2018 In : Oncotarget. 9, 32, p. 22436-22450 15 p.

Research output: Contribution to journalArticle

Tumor Microenvironment
Serine Proteases
Prostate-Specific Antigen
Prostatic Neoplasms
Peptide Hydrolases

Androgen Receptor Splice Variants Are Not Substrates of Nonsense-Mediated Decay

Ajiboye, A. S., Esopi, D., Yegnasubramanian, S. & Denmeade, S. R. Jun 1 2017 In : Prostate. 77, 8, p. 829-837 9 p.

Research output: Contribution to journalArticle

Androgen Receptors
Androgens
Cell Line
Castration
Androgen Receptor Antagonists
Emetine
Prodrugs
Prostate-Specific Antigen
Toxicity
Derivatives