S Yegnasubramanian

Associate Professor

19992019
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Fingerprint Dive into the research topics where S Yegnasubramanian is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 2 Similar Profiles
Prostatic Neoplasms Medicine & Life Sciences
Prostate Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Epigenomics Medicine & Life Sciences
DNA Medicine & Life Sciences
DNA Methylation Medicine & Life Sciences
CpG Islands Medicine & Life Sciences
Androgen Receptors Medicine & Life Sciences

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Research Output 1999 2019

A high-throughput screen of pharmacologically active compounds for inhibitors of UHRF1 reveals epigenetic activity of anthracycline derivative chemotherapeutic drugs

Giovinazzo, H., Walker, D., Wyhs, N., Liu, J., Esopi, D. M., Vaghasia, A. M., Jain, Y., Bhamidipati, A., Zhou, J., Nelson, W. G. & Yegnasubramanian, S., Apr 30 2019, In : Oncotarget. 10, 32, p. 3040-3050 11 p.

Research output: Contribution to journalArticle

Anthracyclines
Epigenomics
DNA
Mitoxantrone
Fluorescence Resonance Energy Transfer

Chromatin dysregulation and DNA methylation at transcription start sites associated with transcriptional repression in cancers

Ando, M., Saito, Y., Xu, G., Bui, N. Q., Medetgul-Ernar, K., Pu, M., Fisch, K., Ren, S., Sakai, A., Fukusumi, T., Liu, C., Haft, S., Pang, J., Mark, A., Gaykalova, D., Guo, T., Favorov, A., Yegnasubramanian, S., Fertig, E., Ha, P. & 5 others, Tamayo, P., Yamasoba, T., Ideker, T., Messer, K. & Califano, J. A., Dec 1 2019, In : Nature communications. 10, 1, 2188.

Research output: Contribution to journalArticle

Open Access
chromatin
methylation
Transcription Initiation Site
DNA Methylation
Chromatin

Consequences of interleukin 1β-triggered chronic inflammation in the mouse prostate gland: Altered architecture associated with prolonged CD4 + infiltration mimics human proliferative inflammatory atrophy

Ashok, A., Keener, R. A., Rubenstein, M., Stookey, S., Bajpai, S., Hicks, J., Alme, A. K., Drake, C. G., Zheng, Q., Trabzonlu, L., Yegnasubramanian, S., Demarzo, A. M. & Bieberich, C. J., Jan 1 2019, In : Prostate.

Research output: Contribution to journalArticle

Interleukin-1
Atrophy
Prostate
Inflammation
Transgenes

Defining UHRF1 Domains that Support Maintenance of Human Colon Cancer DNA Methylation and Oncogenic Properties

Kong, X., Chen, J., Xie, W., Brown, S. M., Cai, Y., Wu, K., Fan, D., Nie, Y., Yegnasubramanian, S., Tiedemann, R. L., Tao, Y., Yen, R-W., Topper, M. J., Zahnow, C., Easwaran, H., Rothbart, S. B., Xia, L. & Baylin, S. B., Apr 15 2019, In : Cancer cell. 35, 4, p. 633-648.e7

Research output: Contribution to journalArticle

DNA Methylation
Colonic Neoplasms
Colorectal Neoplasms
Ubiquitin-Protein Ligases
Tumor Suppressor Genes

Immunogenicity of prostate cancer is augmented by BET bromodomain inhibition

Mao, W., Ghasemzadeh, A., Freeman, Z. T., Obradovic, A., Chaimowitz, M. G., Nirschl, T. R., McKiernan, E., Yegnasubramanian, S. & Drake, C. G., Oct 25 2019, In : Journal for immunotherapy of cancer. 7, 1, 277.

Research output: Contribution to journalArticle

Open Access
Prostatic Neoplasms
Immunotherapy
Genome
T-Lymphocytes
Neoplasms