Research output per year
Research output per year
- 48 results
Search results
-
2022
miRNAs/Small Noncoding RNAs
Fukunaga, R., Jan 1 2022, Encyclopedia of Cell Biology: Volume 1-6, Second Edition. Elsevier, Vol. 1. p. 454-464 11 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
-
2021
Differences in molecular phenotype in mouse and human hypertrophic cardiomyopathy
Vakrou, S., Liu, Y., Zhu, L., Greenland, G. V., Simsek, B., Hebl, V. B., Guan, Y., Woldemichael, K., Talbot, C. C., Aon, M. A., Fukunaga, R. & Abraham, M. R., Dec 2021, In: Scientific reports. 11, 1, 13163.Research output: Contribution to journal › Article › peer-review
Open Access -
RNA-binding protein Maca is crucial for gigantic male fertility factor gene expression, spermatogenesis, and male fertility, in Drosophila
Zhu, L. & Fukunaga, R., Jun 28 2021, In: PLoS genetics. 17, 6, e1009655.Research output: Contribution to journal › Article › peer-review
Open Access -
2019
Author Correction: LOTUS domain protein MARF1 binds CCR4-NOT deadenylase complex to post-transcriptionally regulate gene expression in oocytes (Nature Communications, (2018), 9, 1, (4031), 10.1038/s41467-018-06404-w)
Zhu, L., Kandasamy, S. K., Liao, S. E. & Fukunaga, R., Dec 1 2019, In: Nature communications. 10, 1, 1074.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
DEAD-box RNA helicase Belle posttranscriptionally promotes gene expression in an ATPase activity-dependent manner
Liao, S. E., Kandasamy, S. K., Zhu, L. & Fukunaga, R., 2019, In: RNA. 27, 5, p. 825-839 15 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Differences in microRNA-29 and Pro-fibrotic Gene Expression in Mouse and Human Hypertrophic Cardiomyopathy
Liu, Y., Afzal, J., Vakrou, S., Greenland, G. V., Talbot, C. C., Hebl, V. B., Guan, Y., Karmali, R., Tardiff, J. C., Leinwand, L. A., Olgin, J. E., Das, S., Fukunaga, R. & Abraham, M. R., Dec 17 2019, In: Frontiers in Cardiovascular Medicine. 6, 170.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Drosophila Regnase-1 RNase is required for mRNA and miRNA profile remodelling during larva-to-adult metamorphosis
Zhu, L., Liao, S. E. & Fukunaga, R., Oct 3 2019, In: RNA Biology. 16, 10, p. 1386-1400 15 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
RNA methyltransferase BCDIN3D is crucial for female fertility and miRNA and mRNA profiles in Drosophila ovaries
Zhu, L., Liao, S. E., Ai, Y. & Fukunaga, R., May 2019, In: PloS one. 14, 5, e0217603.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
2018
Allele-specific differences in transcriptome, miRNome, and mitochondrial function in two hypertrophic cardiomyopathy mouse models
Vakrou, S., Fukunaga, R., Foster, D. B., Sorensen, L., Liu, Y., Guan, Y., Woldemichael, K., Pineda-Reyes, R., Liu, T., Tardiff, J. C., Leinwand, L. A., Tocchetti, C. G., Abraham, T. P., O'Rourke, B., Aon, M. A. & Abraham, M. R., Mar 22 2018, In: JCI Insight. 3, 6Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
An RNA-binding protein Blanks plays important roles in defining small RNA and mRNA profiles in Drosophila testes
Liao, S. E., Ai, Y. & Fukunaga, R., Jul 2018, In: Heliyon. 4, 7, e00706.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Dicer partner protein tunes the length of miRNAs using base-mismatch in the pre-miRNA stem
Zhu, L., Kandasamy, S. K. & Fukunaga, R., Apr 20 2018, In: Nucleic acids research. 46, 7, p. 3726-3741 16 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Kinetic analysis of small silencing RNA production by human and Drosophila dicer enzymes in vitro
Liao, S. E. & Fukunaga, R., 2018, Methods in Molecular Biology. Humana Press Inc., p. 101-121 21 p. (Methods in Molecular Biology; vol. 1680).Research output: Chapter in Book/Report/Conference proceeding › Chapter
1 Scopus citations -
Loquacious-PD removes phosphate inhibition of Dicer-2 processing of hairpin RNAs into siRNAs
Fukunaga, R., Apr 15 2018, In: Biochemical and Biophysical Research Communications. 498, 4, p. 1022-1027 6 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
LOTUS domain protein MARF1 binds CCR4-NOT deadenylase complex to post-transcriptionally regulate gene expression in oocytes
Zhu, L., Kandasamy, S. K., Liao, S. E. & Fukunaga, R., Dec 1 2018, In: Nature communications. 9, 1, 4031.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
2017
The C-terminal dsRNA-binding domain of Drosophila Dicer-2 is crucial for efficient and high-fidelity production of siRNA and loading of siRNA to Argonaute2
Kandasamy, S. K., Zhu, L. & Fukunaga, R., Jul 2017, In: RNA. 23, 7, p. 1139-1153 15 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
2016
Common miR-590 variant rs6971711 present only in African Americans reduces miR-590 biogenesis
Lin, X., Steinberg, S., Kandasamy, S. K., Afzal, J., Mbiyangandu, B., Liao, S. E., Guan, Y., Corona-Villalobos, C. P., Matkovich, S. J., Epstein, N., Tripodi, D., Huo, Z., Cutting, G., Abraham, T. P., Fukunaga, R. & Abraham, M. R., May 1 2016, In: PloS one. 11, 5, e0156065.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
miRNAs/Small Noncoding RNAs
Fukunaga, R., Jan 1 2016, Molecular Cell Biology. Elsevier Inc., Vol. 1. p. 354-363 10 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
-
Phosphate-binding pocket in Dicer-2 PAZ domain for high-fidelity siRNA production
Kandasamy, S. K. & Fukunaga, R., Dec 6 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 49, p. 14031-14036 6 p.Research output: Contribution to journal › Article › peer-review
Open Access25 Scopus citations -
2015
A SelB/EF-Tu/aIF2γ-like protein from Methanosarcina mazei in the GTP-bound form binds cysteinyl-tRNACys
Yanagisawa, T., Ishii, R., Hikida, Y., Fukunaga, R., Sengoku, T., Sekine, S. I. & Yokoyama, S., Mar 2015, In: Journal of Structural and Functional Genomics. 16, 1, p. 25-41 17 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
2014
A universal small molecule, inorganic phosphate, restricts the substrate specificity of Dicer-2 in small RNA biogenesis
Fukunaga, R. & Zamore, P. D., Jun 1 2014, In: Cell Cycle. 13, 11, p. 1671-1676 6 p.Research output: Contribution to journal › Review article › peer-review
Open Access3 Scopus citations -
Inorganic phosphate blocks binding of pre-miRNA to Dicer-2 via its PAZ domain
Fukunaga, R., Colpan, C., Han, B. W. & Zamore, P. D., Feb 18 2014, In: EMBO Journal. 33, 4, p. 371-384 14 p.Research output: Contribution to journal › Article › peer-review
Open Access27 Scopus citations -
2012
Dicer partner proteins tune the length of mature miRNAs in flies and mammals
Fukunaga, R., Han, B. W., Hung, J. H., Xu, J., Weng, Z. & Zamore, P. D., Oct 26 2012, In: Cell. 151, 3, p. 533-546 14 p.Research output: Contribution to journal › Article › peer-review
Open Access122 Scopus citations -
Erratum: Dicer partner proteins tune the length of mature miRNAs in flies and mammals (Cell (2012) 151 (533-546))
Fukunaga, R., Han, B. W., Hung, J. H., Xu, J., Weng, Z. & Zamore, P. D., Nov 9 2012, In: Cell. 151, 4, p. 912 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access6 Scopus citations -
Loquacious, a Dicer Partner Protein, Functions in Both the MicroRNA and siRNA Pathways
Fukunaga, R. & Zamore, P. D., 2012, Enzymes. Academic Press, p. 37-68 32 p. (Enzymes; vol. 32).Research output: Chapter in Book/Report/Conference proceeding › Chapter
3 Scopus citations -
2011
Phosphate and R2D2 Restrict the Substrate Specificity of Dicer-2, an ATP-Driven Ribonuclease
Cenik, E. S., Fukunaga, R., Lu, G., Dutcher, R., Wang, Y., Tanaka Hall, T. M. & Zamore, P. D., Apr 22 2011, In: Molecular cell. 42, 2, p. 172-184 13 p.Research output: Contribution to journal › Article › peer-review
Open Access86 Scopus citations -
2010
Riding in silence: A little snowboarding, a lot of small RNAs
Ameres, S. L. & Fukunaga, R., Mar 15 2010, In: Silence. 1, 1, 8.Research output: Contribution to journal › Review article › peer-review
Open Access3 Scopus citations -
2009
dsRNA with 5′ overhangs contributes to endogenous and antiviral RNA silencing pathways in plants
Fukunaga, R. & Doudna, J. A., Mar 4 2009, In: EMBO Journal. 28, 5, p. 545-555 11 p.Research output: Contribution to journal › Article › peer-review
100 Scopus citations -
Unique protein architecture of alanyl-tRNA synthetase for aminoacylation, editing, and dimerization
Naganuma, M., Sekine, S. I., Fukunaga, R. & Yokoyama, S., May 26 2009, In: Proceedings of the National Academy of Sciences of the United States of America. 106, 21, p. 8489-8494 6 p.Research output: Contribution to journal › Article › peer-review
Open Access36 Scopus citations -
2008
Crystallographic Studies on Multiple Conformational States of Active-site Loops in Pyrrolysyl-tRNA Synthetase
Yanagisawa, T., Ishii, R., Fukunaga, R., Kobayashi, T., Sakamoto, K. & Yokoyama, S., May 2 2008, In: Journal of molecular biology. 378, 3, p. 634-652 19 p.Research output: Contribution to journal › Article › peer-review
68 Scopus citations -
Multistep Engineering of Pyrrolysyl-tRNA Synthetase to Genetically Encode Nε-(o-Azidobenzyloxycarbonyl) lysine for Site-Specific Protein Modification
Yanagisawa, T., Ishii, R., Fukunaga, R., Kobayashi, T., Sakamoto, K. & Yokoyama, S., Nov 24 2008, In: Chemistry and Biology. 15, 11, p. 1187-1197 11 p.Research output: Contribution to journal › Article › peer-review
Open Access211 Scopus citations -
Phosphoserine aminoacylation of tRNA bearing an unnatural base anticodon
Fukunaga, R., Harada, Y., Hirao, I. & Yokoyama, S., Aug 1 2008, In: Biochemical and Biophysical Research Communications. 372, 3, p. 480-485 6 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
2007
Crystallization and preliminary X-ray crystallographic study of alanyl-tRNA synthetase from the archaeon Archaeoglobus fulgidus
Fukunaga, R. & Yokoyama, S., Feb 13 2007, In: Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 63, 3, p. 224-228 5 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Structural insights into the first step of RNA-dependent cysteine biosynthesis in archaea
Fukunaga, R. & Yokoyama, S., Apr 2007, In: Nature Structural and Molecular Biology. 14, 4, p. 272-279 8 p.Research output: Contribution to journal › Article › peer-review
45 Scopus citations -
Structural Insights into the Second Step of RNA-dependent Cysteine Biosynthesis in Archaea: Crystal Structure of Sep-tRNA:Cys-tRNA Synthase from Archaeoglobus fulgidus
Fukunaga, R. & Yokoyama, S., Jun 29 2007, In: Journal of molecular biology. 370, 1, p. 128-141 14 p.Research output: Contribution to journal › Article › peer-review
34 Scopus citations -
Structure of the AlaX-M trans-editing enzyme from Pyrococcus horikoshii
Fukunaga, R. & Yokoyama, S., Feb 21 2007, In: Acta Crystallographica Section D: Biological Crystallography. 63, 3, p. 390-400 11 p.Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
The C-terminal domain of the archaeal leucyl-tRNA synthetase prevents misediting of isoleucyl-tRNAIle
Fukunaga, R. & Yokoyama, S., May 1 2007, In: Biochemistry. 46, 17, p. 4985-4996 12 p.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
2006
Crystallization and preliminary X-ray crystallographic analysis of the catalytic domain of pyrrolysyl-tRNA synthetase from the methanogenic archaeon Methanosarcina mazei
Ishii, R., Nureki, O., Yanagisawa, T., Fukunaga, R. & Yokoyama, S., Oct 2006, In: Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 62, 10, p. 1031-1033 3 p.Research output: Contribution to journal › Article › peer-review
30 Scopus citations -
Structural and mutational studies of the amino acid-editing domain from archaeal/eukaryal phenylalanyl-tRNA synthetase
Sasaki, H. M., Sekine, S. I., Sengoku, T., Fukunaga, R., Hattori, M., Utsunomiya, Y., Kuroishi, C., Kuramitsu, S., Shirouzu, M. & Yokoyama, S., Oct 3 2006, In: Proceedings of the National Academy of Sciences of the United States of America. 103, 40, p. 14744-14749 6 p.Research output: Contribution to journal › Article › peer-review
28 Scopus citations -
Structural Basis for Substrate Recognition by the Editing Domain of Isoleucyl-tRNA Synthetase
Fukunaga, R. & Yokoyama, S., Jun 16 2006, In: Journal of molecular biology. 359, 4, p. 901-912 12 p.Research output: Contribution to journal › Article › peer-review
49 Scopus citations -
2005
Aminoacylation complex structures of leucyl-tRNA synthetase and tRNA Leu reveal two modes of discriminator-base recognition
Fukunaga, R. & Yokoyama, S., Oct 2005, In: Nature Structural and Molecular Biology. 12, 10, p. 915-922 8 p.Research output: Contribution to journal › Article › peer-review
87 Scopus citations -
Crystallization of leucyl-tRNA synthetase complexed with tRNALeu from the archaeon Pyrococcus horikoshii
Fukunaga, R., Ishitani, R., Nureki, O. & Yokoyama, S., 2005, In: Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 61, 1, p. 30-32 3 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Crystal structure of leucyl-tRNA synthetase from the archaeon Pyrococcus horikoshii reveals a novel editing domain orientation
Fukunaga, R. & Yokoyama, S., Feb 11 2005, In: Journal of molecular biology. 346, 1, p. 57-71 15 p.Research output: Contribution to journal › Article › peer-review
75 Scopus citations -
Crystal structure of tRNA adenosine deaminase (TadA) from Aquifex aeolicus
Kuratani, M., Ishii, R., Bessho, Y., Fukunaga, R., Sengoku, T., Shirouzu, M., Sekine, S. I. & Yokoyama, S., Apr 22 2005, In: Journal of Biological Chemistry. 280, 16, p. 16002-16008 7 p.Research output: Contribution to journal › Article › peer-review
Open Access46 Scopus citations -
Structural basis for non-cognate amino acid discrimination by the valyl-tRNA synthetase editing domain
Fukunaga, R. & Yokoyama, S., Aug 19 2005, In: Journal of Biological Chemistry. 280, 33, p. 29937-29945 9 p.Research output: Contribution to journal › Article › peer-review
Open Access31 Scopus citations -
The crystal structure of leucyl-tRNA synthetase complexed with tRNA Leu in the post-transfer-editing conformation
Tukalo, M., Yaremchuk, A., Fukunaga, R., Yokoyama, S. & Cusack, S., Oct 2005, In: Nature Structural and Molecular Biology. 12, 10, p. 923-930 8 p.Research output: Contribution to journal › Article › peer-review
128 Scopus citations -
2004
Crystallization and preliminary X-ray crystallographic study of leucyl-tRNA synthetase from the archaeon Pyrococcus horikoshii
Fukunaga, R. & Yokoyama, S., Oct 2004, In: Acta Crystallographica Section D: Biological Crystallography. 60, 10, p. 1916-1918 3 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Crystallization and preliminary X-ray crystallographic study of the editing domain of Thermus thermophilus isoleucyl-tRNA synthetase complexed with pre- and post-transfer editing-substrate analogues
Fukunaga, R. & Yokoyama, S., Oct 2004, In: Acta Crystallographica Section D: Biological Crystallography. 60, 10, p. 1900-1902 3 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Crystal Structures of the CP1 Domain from Thermus thermophilus Isoleucyl-tRNA Synthetase and Its Complex with L-Valine
Fukunaga, R., Fukai, S., Ishitani, R., Nureki, O. & Yokoyama, S., Feb 27 2004, In: Journal of Biological Chemistry. 279, 9, p. 8396-8402 7 p.Research output: Contribution to journal › Article › peer-review
Open Access45 Scopus citations