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Amino Acyl-tRNA Synthetases Medicine & Life Sciences
Proteins Medicine & Life Sciences
Transfer RNA Medicine & Life Sciences
Archaea Medicine & Life Sciences
MicroRNAs Medicine & Life Sciences
RNA Medicine & Life Sciences
Small Interfering RNA Medicine & Life Sciences
Crystallization Medicine & Life Sciences

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Research Output 2004 2018

Kinetic analysis of small silencing RNA production by human and Drosophila dicer enzymes in vitro

Liao, S. E. & Fukunaga, R. 2018 Methods in Molecular Biology. Humana Press Inc., Vol. 1680, p. 101-121 21 p. (Methods in Molecular Biology; vol. 1680)

Research output: ResearchChapter

Ribonuclease III
RNA Interference
Drosophila
RNA
In Vitro Techniques

The C-terminal dsRNA-binding domain of Drosophila Dicer-2 is crucial for efficient and high-fidelity production of siRNA and loading of siRNA to Argonaute2

Kandasamy, S. K., Zhu, L. & Fukunaga, R. Jul 1 2017 In : RNA. 23, 7, p. 1139-1153 15 p.

Research output: Research - peer-reviewArticle

Small Interfering RNA
Drosophila
Nucleotides
Double-Stranded RNA Binding Motif
RNA Interference

Common miR-590 variant rs6971711 present only in African Americans reduces miR-590 biogenesis

Lin, X., Steinberg, S., Kandasamy, S. K., Afzal, J., Mbiyangandu, B., Liao, S. E., Guan, Y., Corona-Villalobos, C. P., Matkovich, S. J., Epstein, N., Tripodi, D., Huo, Z., Cutting, G., Abraham, T. P., Fukunaga, R. & Abraham, M. R. May 1 2016 In : PLoS One. 11, 5, e0156065

Research output: Research - peer-reviewArticle

African Americans
microRNA
biogenesis
MicroRNAs
Single Nucleotide Polymorphism

Phosphate-binding pocket in Dicer-2 PAZ domain for high-fidelity siRNA production

Kandasamy, S. K. & Fukunaga, R. Dec 6 2016 In : Proceedings of the National Academy of Sciences of the United States of America. 113, 49, p. 14031-14036 6 p.

Research output: Research - peer-reviewArticle

Small Interfering RNA
Phosphates
RNA Interference
MicroRNAs
Ribonuclease III

A SelB/EF-Tu/aIF2γ-like protein from Methanosarcina mazei in the GTP-bound form binds cysteinyl-tRNACys

Yanagisawa, T., Ishii, R., Hikida, Y., Fukunaga, R., Sengoku, T., Sekine, S. I. & Yokoyama, S. 2015 In : Journal of Structural and Functional Genomics. 16, 1, p. 25-41 17 p.

Research output: Research - peer-reviewArticle

Methanosarcina
Peptide Elongation Factor Tu
Transfer RNA
Guanosine Triphosphate
Proteins