Research Output 2008 2018

2018

A Comprehensive Risk Score to Predict Prolonged Hospital Length of Stay After Heart Transplantation

Crawford, T. C., Magruder, J. T., Grimm, J. C., Suarez-Pierre, A., Patel, N., Sciortino, C. M., Zehr, K. J., Mandal, K., Tedford, R. J., Russell, S. D., Conte, J. V., Higgins, R. S., Cameron, D. E. & Whitman, G. J. Jan 1 2018 In : Annals of Thoracic Surgery. 105, 1, p. 83-90 8 p.

Research output: Research - peer-reviewArticle

Heart Transplantation
Length of Stay
Hospitalization
Transplants
Transplant Recipients
2017

Acute kidney injury and 1-year mortality after left ventricular assist device implantation

Muslem, R., Caliskan, K., Akin, S., Sharma, K., Gilotra, N. A., Constantinescu, A. A., Houston, B., Whitman, G., Tedford, R. J., Hesselink, D. A., Bogers, A. J. J. C., Russell, S. D. & Manintveld, O. C. Jan 1 2017 (Accepted/In press) In : Journal of Heart and Lung Transplantation.

Research output: Research - peer-reviewArticle

Heart-Assist Devices
Acute Kidney Injury
Mortality
Heart Ventricles
Kidney

A new "twist" on right heart failure with left ventricular assist systems

Houston, B. A., Shah, K. B., Mehra, M. R. & Tedford, R. J. 2017 (Accepted/In press) In : Journal of Heart and Lung Transplantation.

Research output: Research - peer-reviewArticle

Heart Ventricles
Heart Failure
Pericardium
Morbidity
Phenotype

Angiotensin II antagonism is associated with reduced risk for gastrointestinal bleeding caused by arteriovenous malformations in patients with left ventricular assist devices

Houston, B. A., Schneider, A. L. C., Vaishnav, J., Cromwell, D. M., Miller, P. E., Faridi, K. F., Shah, A., Sciortino, C., Whitman, G., Tedford, R. J., Stevens, G. R., Judge, D. P., Russell, S. D. & Rouf, R. 2017 (Accepted/In press) In : Journal of Heart and Lung Transplantation.

Research output: Research - peer-reviewArticle

Heart-Assist Devices
Arteriovenous Malformations
Angiotensin II
Hemorrhage
Angiotensin Receptor Antagonists

A systematic review of transition studies of pulmonary arterial hypertension specific medications

Sofer, A., Ryan, M. J., Tedford, R. J., Wirth, J. A. & Fares, W. H. 2017 In : Pulmonary Circulation. 7, 2, p. 326-338 13 p.

Research output: Research - peer-reviewReview article

Pulmonary Hypertension
Epoprostenol
United States Food and Drug Administration
Hemodynamics
Therapeutics

A tale of two hearts: Patients with decompensated right heart failure in the intensive care unit

Wenger, D. S., Krieger, E. V., Ralph, D. D., Tedford, R. J. & Leary, P. J. Jun 1 2017 In : Annals of the American Thoracic Society. 14, 6, p. 1025-1030 6 p.

Research output: Research - peer-reviewArticle

Intensive Care Units
Heart Failure
Atrial Fibrillation
Ovum
Chickens
Heart Failure

Balancing the positives and negatives of the diastolic pulmonary gradient

Tampakakis, E. & Tedford, R. J. Jan 1 2017 In : European Journal of Heart Failure. 19, 1, p. 98-100 3 p.

Research output: Research - peer-reviewEditorial

Lung

Concomitant mitral valve procedures in patients undergoing implantation of continuous-flow left ventricular assist devices: An INTERMACS database analysis

Robertson, J. O., Naftel, D. C., Myers, S. L., Tedford, R. J., Joseph, S. M., Kirklin, J. K. & Silvestry, S. C. Jan 1 2017 (Accepted/In press) In : Journal of Heart and Lung Transplantation.

Research output: Research - peer-reviewArticle

Heart-Assist Devices
Mitral Valve
Registries
Databases
Survival

Effect of Age and Renal Function on Survival After Left Ventricular Assist Device Implantation

Muslem, R., Caliskan, K., Akin, S., Yasar, Y. E., Sharma, K., Gilotra, N. A., Kardys, I., Houston, B., Whitman, G., Tedford, R. J., Hesselink, D. A., Bogers, A. J. J. C., Manintveld, O. C. & Russell, S. D. 2017 (Accepted/In press) In : American Journal of Cardiology.

Research output: Research - peer-reviewArticle

Heart-Assist Devices
Kidney
Survival
Glomerular Filtration Rate
Mortality

Evaluation of criteria for exerciseinduced pulmonary hypertension in patients with resting pulmonary hypertension

Mullin, C. J., Hsu, S., Amancherla, K., Wand, A., Rhodes, P., Leary, P. J., Mukherjee, M., Damico, R. L., Kolb, T. M., Mathai, S. C., Hassoun, P. M. & Tedford, R. J. Sep 1 2017 In : European Respiratory Journal. 50, 3, 00784

Research output: Research - peer-reviewLetter

Pulmonary Hypertension

Evaluation of structural progression in arrhythmogenic right ventricular dysplasia/cardiomyopathy

Mast, T. P., James, C. A., Calkins, H., Teske, A. J., Tichnell, C., Murray, B., Loh, P., Russell, S. D., Velthuis, B. K., Judge, D. P., Dooijes, D., Tedford, R. J., Van Der Heijden, J. F., Tandri, H., Hauer, R. N., Abraham, T. P., Doevendans, P. A., Te Riele, A. S. J. M. & Cramer, M. J. Mar 1 2017 In : JAMA Cardiology. 2, 3, p. 293-302 10 p.

Research output: Research - peer-reviewArticle

Arrhythmogenic Right Ventricular Dysplasia
Advisory Committees
Odds Ratio
Left Ventricular Function
Stroke Volume

Even on a large scale, weight may not matter

Gilotra, N. A. & Tedford, R. J. May 1 2017 In : Circulation: Cardiovascular Quality and Outcomes. 10, 5, e003825

Research output: Research - peer-reviewEditorial

Weights and Measures

Genetic testing improves identification of transthyretin amyloid (ATTR) subtype in cardiac amyloidosis

Brown, E. E., Lee, Y. Z. J., Halushka, M. K., Steenbergen, C., Johnson, N. M., Almansa, J., Tedford, R. J., Cingolani, O., Russell, S. D., Sharma, K. & Judge, D. P. May 11 2017 (Accepted/In press) In : Amyloid. p. 1-4 4 p.

Research output: Research - peer-reviewArticle

Prealbumin
Genetic Testing
Amyloidosis
Amyloid
Mutation

Heart Failure Is Common and Under-Recognized in Patients With Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia

Gilotra, N. A., Bhonsale, A., James, C. A., Te Riele, A. S. J., Murray, B., Tichnell, C., Sawant, A., Ong, C. S., Judge, D. P., Russell, S. D., Calkins, H. & Tedford, R. J. Sep 1 2017 In : Circulation. Heart failure. 10, 9

Research output: Research - peer-reviewArticle

Arrhythmogenic Right Ventricular Dysplasia
Heart Failure
Odds Ratio
Confidence Intervals
Advisory Committees

Histamine H2 Receptor Polymorphisms, Myocardial Transcripts, and Heart Failure (from the Multi-Ethnic Study of Atherosclerosis and Beta-Blocker Effect on Remodeling and Gene Expression Trial)

Leary, P. J., Kronmal, R. A., Bluemke, D. A., Buttrick, P. M., Jones, K. L., Kao, D. P., Kawut, S. M., Krieger, E. V., Lima, J. A., Minobe, W., Ralph, D. D., Tedford, R. J., Weiss, N. S. & Bristow, M. R. Jan 1 2017 (Accepted/In press) In : American Journal of Cardiology.

Research output: Research - peer-reviewArticle

Histamine
Atherosclerosis
Heart Failure
Gene Expression
Single Nucleotide Polymorphism

Is pulmonary artery wedge pressure a Fib in A-Fib?

Houston, B. A. & Tedford, R. J. 2017 (Accepted/In press) In : European Journal of Heart Failure.

Research output: Research - peer-reviewArticle

Pulmonary Wedge Pressure

Long-term follow-up of continuous flow left ventricular assist devices: Complications and predisposing risk factors

Adesiyun, T. A., McLean, R. C., Tedford, R. J., Whitman, G. J. R., Sciortino, C. M., Conte, J. V., Shah, A. S. & Russell, S. D. 2017 In : International Journal of Artificial Organs. 40, 11, p. 622-628 7 p.

Research output: Research - peer-reviewArticle

Heart-Assist Devices
Blood Urea Nitrogen
Causality
Odds Ratio
Left ventricular assist devices

Poor survival in patients with scleroderma and pulmonary hypertension due to heart failure with preserved ejection fraction

Bourji, K. I., Kelemen, B. W., Mathai, S. C., Damico, R. L., Kolb, T. M., Mercurio, V., Cozzi, F., Tedford, R. J. & Hassoun, P. M. 2017 In : Pulmonary Circulation. 7, 2, p. 409-420 12 p.

Research output: Research - peer-reviewArticle

Systemic Scleroderma
Pulmonary Hypertension
Heart Failure
Survival
Cardiac Catheterization

Pre-operative proteinuria in left ventricular assist devices and clinical outcome

Muslem, R., Caliskan, K., Akin, S., Sharma, K., Gilotra, N. A., Brugts, J. J., Houston, B., Whitman, G., Tedford, R. J., Hesselink, D. A., Bogers, A. J. J. C., Manintveld, O. C. & Russell, S. D. 2017 (Accepted/In press) In : Journal of Heart and Lung Transplantation.

Research output: Research - peer-reviewArticle

Heart-Assist Devices
Proteinuria
Renal Replacement Therapy
Mortality
Confidence Intervals
Heart Failure
Kidney
Hospitalization
Right Ventricular Dysfunction
Right Ventricular Function

Right ventricular response to pulsatile load is associated with early right heart failure and mortality after left ventricular assist device

Grandin, E. W., Zamani, P., Mazurek, J. A., Troutman, G. S., Birati, E. Y., Vorovich, E., Chirinos, J. A., Tedford, R. J., Margulies, K. B., Atluri, P. & Rame, J. E. Jan 1 2017 In : Journal of Heart and Lung Transplantation. 36, 1, p. 97-105 9 p.

Research output: Research - peer-reviewArticle

Heart-Assist Devices
Heart Failure
Mortality
Confidence Intervals
Lung Compliance

RV pressure overload: From hypertrophy to failure

Van Der Bruggen, C. E. E., Tedford, R. J., Handoko, M. L., Van Der Velden, J. & De Man, F. S. Oct 1 2017 In : Cardiovascular Research. 113, 12, p. 1423-1432 10 p.

Research output: Research - peer-reviewReview article

Ventricular Pressure
Hypertrophy
Pulmonary Hypertension
Systemic Scleroderma
Fibrosis

The authors reply

Metkus, T. S., Mathai, S. C. & Tedford, R. J. Aug 1 2017 In : Critical Care Medicine. 45, 8, p. e874-e875

Research output: Research - peer-reviewLetter

Thermodilution vs estimated Fick cardiac output measurement in clinical practice: An analysis of mortality from the Veterans Affairs Clinical Assessment, Reporting, and Tracking (VA CART) program and Vanderbilt University

Opotowsky, A. R., Hess, E., Maron, B. A., Brittain, E. L., Barón, A. E., Maddox, T. M., Alshawabkeh, L. I., Wertheim, B. M., Xu, M., Assad, T. R., Rich, J. D., Choudhary, G. & Tedford, R. J. Oct 1 2017 In : JAMA Cardiology. 2, 10, p. 1090-1099 10 p.

Research output: Research - peer-reviewArticle

Thermodilution
Veterans
Cardiac Output
Mortality
Cardiac Catheterization

Use of thermodilution cardiac output overestimates diagnoses of exercise-induced pulmonary hypertension

Hsu, S., Brusca, S. B., Rhodes, P. S., Kolb, T. M., Mathai, S. C. & Tedford, R. J. Jan 1 2017 In : Pulmonary Circulation. 7, 1, p. 253-255 3 p.

Research output: Research - peer-reviewLetter

Thermodilution
Pulmonary Hypertension
Cardiac Output
Exercise

What's in a side effect? The association between pulmonary vasodilator adverse drug events and clinical outcomes in patients with pulmonary arterial hypertension

Leary, P. J., Kang, S., Kolb, T. M., Maron, B. A., Ralph, D. D., Rao, Y., Tedford, R. J. & Zamanian, R. T. Jan 23 2017 (Accepted/In press) In : International Journal of Cardiology.

Research output: Research - peer-reviewArticle

Drug-Related Side Effects and Adverse Reactions
Vasodilator Agents
Pulmonary Hypertension
Lung
treprostinil

What we talk about when we talk about the wedge pressure

Houston, B. A. & Tedford, R. J. Sep 1 2017 In : Circulation: Heart Failure. 10, 9, e004450

Research output: Research - peer-reviewReview article

Pulmonary Wedge Pressure
Vascular Diseases
Pulmonary Hypertension
Heart Failure
Hemodynamics
2016

Association of Borderline Pulmonary Hypertension With Mortality and Hospitalization in a Large Patient Cohort: Insights From the VA-CART Program

Maron, B. A., Hess, E., Maddox, T. M., Opotowsky, A. R., Tedford, R. J., Lahm, T., Joynt, K. E., Kass, D. J., Stephens, T., Stanislawski, M. A., Swenson, E. R., Goldstein, R. H., Leopold, J. A., Zamanian, R. T., Elwing, J. M., Plomondon, M. E., Grunwald, G. K., Barón, A. E., Rumsfeld, J. & Choudhary, G. Feb 15 2016 (Accepted/In press) In : Circulation.

Research output: Research - peer-reviewArticle

Pulmonary Hypertension
Hospitalization
Mortality
Pulmonary Artery
Pressure

Association of Pre-Implant Red Blood Cell Distribution Width with Clinical Outcomes Among Individuals with Left Ventricular Assist Devices: LVAD Red Blood Cell Distribution and Mortality

Miller, E. E., Houston, B. A., Schneider, A. L. C., Bush, A., Whitman, G. J., Stevens, G., Tedford, R. J. & Russell, S. D. Aug 22 2016 (Accepted/In press) In : ASAIO Journal.

Research output: Research - peer-reviewArticle

Heart-Assist Devices
Erythrocyte Indices
Erythrocytes
Mortality
Left ventricular assist devices

Baseline Characteristics Predict the Presence of Amyloid on Endomyocardial Biopsy

Ton, V. K., Bhonsale, A., Gilotra, N. A., Halushka, M. K., Steenbergen, C., Almansa, J., Brown, E., Tedford, R. J., Wittstein, I., Sharma, K., Russell, S. D. & Judge, D. P. Mar 7 2016 (Accepted/In press) In : Journal of Cardiac Failure.

Research output: Research - peer-reviewArticle

Amyloidosis
Amyloid
Biopsy
Heart Failure
Peripheral Nervous System Diseases

Cardiac Index Declines During Long-Term Left Ventricular Device Support

Kalathiya, R. J., Houston, B. A., Chaisson, J. M., Grimm, J. C., Stevens, G. R., Sciortino, C. M., Shah, A. S., Whitman, G. J. R., Russell, S. D. & Tedford, R. J. 2016 (Accepted/In press) In : Artificial Organs.

Research output: Research - peer-reviewArticle

Equipment and Supplies
Left ventricular assist devices
Hemodynamics
Heart-Assist Devices
Therapeutics

Heart rate dependence of the pulmonary resistance x compliance (rc) time and impact on right ventricular load

Metkus, T. S., Mullin, C. J., Grandin, E. W., Rame, J. E., Tampakakis, E., Hsu, S., Kolb, T. M., Damico, R., Hassoun, P. M., Kass, D. A., Mathai, S. C. & Tedford, R. J. Nov 1 2016 In : PLoS One. 11, 11, e0166463

Research output: Research - peer-reviewArticle

compliance
heart rate
lungs
Compliance
Heart Rate
Troponin I
Myocarditis
Giant Cells
Serum

Outcomes in Patients Bridged With Univentricular and Biventricular Devices in the Modern Era of Heart Transplantation

Grimm, J. C., Sciortino, C. M., Magruder, J. T., Dungan, S. P., Valero, V., Sharma, K., Tedford, R. J., Russell, S. D., Whitman, G. J. R., Silvestry, S. C. & Shah, A. S. 2016 (Accepted/In press) In : Annals of Thoracic Surgery.

Research output: Research - peer-reviewArticle

Heart Transplantation
Equipment and Supplies
Artificial Heart
Survival
Heart-Assist Devices

Pulmonary Arterial Compliance Improves Rapidly after Left Ventricular Assist Device Implantation

Masri, C. C., Tedford, R. J., Colvin, M. M., Leary, P. J. & Cogswell, R. Nov 9 2016 (Accepted/In press) In : ASAIO Journal.

Research output: Research - peer-reviewArticle

Lung Compliance
Heart-Assist Devices
Left ventricular assist devices
Compliance
Pulmonary Artery
Lung Compliance
Adult Respiratory Distress Syndrome
Catheters
Therapeutics
Vascular Resistance
Right Ventricular Function
Endarterectomy
Exercise Tolerance
Pulmonary Embolism
Pulmonary Hypertension

Reply: Histamine H2 Receptors and Heart Failure: A Complex Cross-Talk

Leary, P. J., Ralph, D. D., Tedford, R. J. & Kronmal, R. A. Aug 1 2016 In : Journal of the American College of Cardiology. 68, 7, p. 775-776 2 p.

Research output: Research - peer-reviewLetter

Histamine H2 Receptors
Heart Failure

Right ventricular afterload sensitivity dramatically increases after left ventricular assist device implantation: A multi-center hemodynamic analysis

Houston, B. A., Kalathiya, R. J., Hsu, S., Loungani, R., Davis, M. E., Coffin, S. T., Haglund, N., Maltais, S., Keebler, M. E., Leary, P. J., Judge, D. P., Stevens, G. R., Rickard, J., Sciortino, C. M., Whitman, G. J., Shah, A. S., Russell, S. D. & Tedford, R. J. 2016 (Accepted/In press) In : Journal of Heart and Lung Transplantation.

Research output: Research - peer-reviewArticle

Heart-Assist Devices
Hemodynamics
Pulmonary Wedge Pressure
Cardiac Catheterization
Lung Compliance

Right Ventricular Functional Reserve in Pulmonary Arterial Hypertension

Hsu, S., Houston, B. A., Tampakakis, E., Bacher, A. C., Rhodes, P. S., Mathai, S. C., Damico, R. L., Kolb, T. M., Hummers, L. K., Shah, A. A., McMahan, Z., Corona-Villalobos, C. P., Zimmerman, S. L., Wigley, F. M., Hassoun, P. M., Kass, D. A. & Tedford, R. J. May 12 2016 (Accepted/In press) In : Circulation.

Research output: Research - peer-reviewArticle

Pulmonary Hypertension
Ergometry
Right Ventricular Function
Systemic Scleroderma
Recycling

Survival After Orthotopic Heart Transplantation in Patients Undergoing Bridge to Transplantation With the HeartWare HVAD Versus the Heartmate II

Magruder, J. T., Grimm, J. C., Crawford, T. C., Tedford, R. J., Russell, S. D., Sciortino, C. M., Whitman, G. J. R. & Shah, A. S. 2016 (Accepted/In press) In : Annals of Thoracic Surgery.

Research output: Research - peer-reviewArticle

Heart Transplantation
Transplantation
Survival
Equipment and Supplies
Tissue Donors
Systemic Scleroderma
Heart Ventricles
Sclerosis
Reference Values
2015

Ambrisentan and tadalafil up-front combination therapy in scleroderma-associated pulmonary arterial hypertension

Hassoun, P. M., Zamanian, R. T., Damico, R., Lechtzin, N., Khair, R., Kolb, T. M., Tedford, R. J., Hulme, O. L., Housten, T., Pisanello, C., Sato, T., Pullins, E. H., Corona-Villalobos, C. P., Zimmerman, S. L., Gashouta, M. A., Minai, O. A., Torres, F., Girgis, R. E., Chin, K. & Mathai, S. C. Nov 1 2015 In : American Journal of Respiratory and Critical Care Medicine. 192, 9, p. 1102-1110 9 p.

Research output: Research - peer-reviewArticle

Pulmonary Hypertension
Therapeutics
ambrisentan
Tadalafil
Brain Natriuretic Peptide

Clinical Presentation, Long-Term Follow-Up, and Outcomes of 1001 Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy Patients and Family Members

Groeneweg, J. A. , Bhonsale, A. , James, C. A. , Te Riele, A. S. , Dooijes, D. , Tichnell, C. , Murray, B. , Wiesfeld, A. C. P. , Sawant, A. C. , Kassamali, B. , Atsma, D. E. , Volders, P. G. , De Groot, N. M. , De Boer, K. , Zimmerman, S. L. , Kamel, I. R. , Van Der Heijden, J. F. , Russell, S. D. , Jan Cramer, M. , Tedford, R. J. & 8 others Doevendans, P. A., Van Veen, T. A., Tandri, H., Wilde, A. A., Judge, D. P., Van Tintelen, J. P., Hauer, R. N. & Calkins, H. Jun 11 2015 In : Circulation: Cardiovascular Genetics. 8, 3, p. 437-446 10 p.

Research output: Research - peer-reviewArticle

Arrhythmogenic Right Ventricular Dysplasia
Mutation
Cardiac Arrhythmias
Implantable Defibrillators
Sudden Cardiac Death

Comparative Efficacy of Cardiac Resynchronization Therapy in Africans Americans Compared with European Americans

Rickard, J., Baranowski, B., Cheng, A., Spragg, D., Tedford, R., Mukherjee, M., Tang, W. H. W., Wilkoff, B. L. & Varma, N. Oct 1 2015 In : The American Journal of Cardiology. 116, 7, p. 1101-1105 5 p.

Research output: Research - peer-reviewArticle

Cardiac Resynchronization Therapy
African Americans
Heart-Assist Devices
Stroke Volume
Transplants

Diagnosing and treating the failing right heart

Ryan, J. J. & Tedford, R. J. May 27 2015 In : Current Opinion in Cardiology. 30, 3, p. 292-300 9 p.

Research output: Research - peer-reviewArticle

Heart Ventricles
Glycolysis
Pulmonary Artery
Morbidity
Mortality

Incidence and early outcomes associated with pre-transplant antivimentin antibodies in the cardiac transplantation population

Young, R. K., Dale, B., Russell, S. D., Zachary, A. A. & Tedford, R. J. Aug 1 2015 In : Clinical Transplantation. 29, 8, p. 685-688 4 p.

Research output: Research - peer-reviewArticle

Heart Transplantation
Transplants
Antibodies
Incidence
Population

Isosorbide mononitrate in heart failure with preserved ejection fraction

Redfield, M. M., Anstrom, K. J., Levine, J. A., Koepp, G. A., Borlaug, B. A., Chen, H. H., LeWinter, M. M., Joseph, S. M., Shah, S. J., Semigran, M. J., Felker, G. M., Cole, R. T., Reeves, G. R., Tedford, R. J., Tang, W. H. W., McNulty, S. E., Velazquez, E. J., Shah, M. R. & Braunwald, E. Dec 10 2015 In : New England Journal of Medicine. 373, 24, p. 2314-2324 11 p.

Research output: Research - peer-reviewArticle

isosorbide-5-mononitrate
Heart Failure
Placebos
Quality of Life
Confidence Intervals