Ronnie Mease

Associate Professor

1984 …2020

Research output per year

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Research Output

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Introduction of five potentially metabolizable linking groups between 111In-cyclohexyl EDTA derivatives and F(ab′)2 fragments of anti-carcinoembryonic antigen antibody-I. A new reproducible synthetic method

Gestin, J. F., Faivre-chauvet, A., Mease, R. C., Sai-maurel, C., Thédrez, P., Slinkin, M., Meinken, G. E., Srivastava, S. C. & Chatal, J. F., Aug 1993, In : Nuclear Medicine and Biology. 20, 6, p. 755-762 8 p.

Research output: Contribution to journalArticle

Introduction of five potentially metabolizable linking groups between 111In-cyclohexyl EDTA derivatives and F(ab′)2 fragments of anti-carcinoembryonic antigen antibody-II. Comparative pharmacokinetics and biodistribution in human colorectal carcinoma-bearing nude mice

Faivre-chauvet, A., Gestin, J. F., Mease, R. C., Sai-maurel, C., Thédrez, P., Slinkin, M., Meinken, G. E., Srivastava, S. C. & Chatal, J. F., Aug 1993, In : Nuclear Medicine and Biology. 20, 6, p. 763-771 9 p.

Research output: Contribution to journalArticle

In vitro and in vivo characterization of dibenzothiophene derivatives [125I]iodo-ASEM and [18F]ASEM as radiotracers of homo- And heteromeric α7 nicotinic acetylcholine receptors

Donat, C. K., Hansen, H. H., Hansen, H. D., Mease, R., Horti, A., Pomper, M. G., L’Estrade, E. T., Herth, M. M., Peters, D., Knudsen, G. M. & Mikkelsen, J. D., Jan 1 2020, In : Molecules. 25, 6, 1425.

Research output: Contribution to journalArticle

Open Access

Iodination of terminal alkynes using KI/CuSO 4 – A facile method with potential for radio-iodination

Ferris, T., Carroll, L., Mease, R., Spivey, A. C. & Aboagye, E. O., Mar 28 2019, In : Tetrahedron Letters. 60, 13, p. 936-939 4 p.

Research output: Contribution to journalArticle

Low-level endogenous PSMA expression in nonprostatic tumor xenografts is sufficient for in vivo tumor targeting and imaging

Nimmagadda, S., Pullambhatla, M., Chen, Y., Parsana, P., Lisok, A., Chatterjee, S., Mease, R., Rowe, S., Lupold, S., Pienta, K. & Pomper, M. G., Mar 1 2018, In : Journal of Nuclear Medicine. 59, 3, p. 486-493 8 p.

Research output: Contribution to journalArticle

MR-Guided Delivery of Hydrophilic Molecular Imaging Agents Across the Blood-Brain Barrier Through Focused Ultrasound

Airan, R. D., Foss, C., Ellens, N., Wang, Y., Mease, R., Farahani, K. & Pomper, M. G., Aug 1 2016, (Accepted/In press) In : Molecular Imaging and Biology. p. 1-7 7 p.

Research output: Contribution to journalArticle

N-[N-[(S)-1,3-dicarboxypropyl]carbamoyl]-4-[18F]fluorobenzyl-L- cysteine, [18F]DCFBC: A new Imaging probe for prostate cancer

Mease, R. C., Dusich, C. L., Foss, C. A., Ravert, H. T., Dannals, R. F., Seidel, J., Prideaux, A., Fox, J. J., Sgouros, G., Kozikowski, A. P. & Pomper, M. G., May 15 2008, In : Clinical Cancer Research. 14, 10, p. 3036-3043 8 p.

Research output: Contribution to journalArticle

Newer methods of labeling diagnostic agents with Tc-99m

Mease, R. C. & Lambert, C., Jan 1 2001, In : Seminars in Nuclear Medicine. 31, 4, p. 278-285 8 p.

Research output: Contribution to journalArticle

Novel substrate-based inhibitors of human glutamate carboxypeptidase II with enhanced lipophilicity

Plechanovová, A., Byun, Y., Alquicer, G., Škultétyová, LU., Mlčochová, P., Němcová, A., Kim, H. J., Navrátil, M., Mease, R., Lubkowski, J., Pomper, M., Konvalinka, J., Rulíšek, L. & Bařinka, C., Nov 10 2011, In : Journal of medicinal chemistry. 54, 21, p. 7535-7546 12 p.

Research output: Contribution to journalArticle

PET imaging in prostate cancer: Focus on prostate-specific membrane antigen

Mease, R. C., Foss, C. A. & Pomper, M. G., Jun 14 2013, In : Current topics in medicinal chemistry. 13, 8, p. 951-962 12 p.

Research output: Contribution to journalArticle

Positron Emission Tomography Imaging with 2-[18F]F- p-Aminobenzoic Acid detects Staphylococcus aureus Infections and Monitors Drug Response

Zhang, Z., Ordonez Suarez, A., Wang, H., Li, Y., Gogarty, K. R., Weinstein, E. A., Daryaee, F., Merino, J., Yoon, G. E., Kalinda, A. S., Mease, R., Iuliano, J. N., Smith-Jones, P., Jain, S. & Tonge, P. J., Jan 1 2018, (Accepted/In press) In : ACS Infectious Diseases.

Research output: Contribution to journalArticle

Pre-clinical and clinical studies of two new bifunctional chelating agents for immunoscintigraphy with 111in-anti-cea monoclonal antibody

Faivre-Chauvet, A., Chetanneau, A., Bardiès, M., Sai-Maurel, C., Chatal, J. F., Gestin, J. F., Mease, R. C., Meinken, G. E. & Srivastava, S. C., Sep 1996, In : Nuclear medicine communications. 17, 9, p. 781-789 9 p.

Research output: Contribution to journalArticle

Preclinical comparative study of 68Ga-labeled DOTA, NOTA, and HBED-CC chelated radiotracers for targeting PSMA

Ray, S., Chen, Z., Pullambhatla, M., Lisok, A., Chen, J., Mease, R. & Pomper, M. G., Jun 15 2016, In : Bioconjugate Chemistry. 27, 6, p. 1447-1455 9 p.

Research output: Contribution to journalArticle

Preclinical evaluation of 86Y-labeled inhibitors of prostate-specific membrane antigen for dosimetry estimates

Banerjee, S. R., Foss, C. A., Pullambhatla, M., Wang, Y., Srinivasan, S., Hobbs, R. F., Baidoo, K. E., Brechbiel, M. W., Nimmagadda, S., Mease, R. C., Sgouros, G. & Pomper, M. G., Apr 1 2015, In : Journal of Nuclear Medicine. 56, 4, p. 628-634 7 p.

Research output: Contribution to journalArticle

Preparation of F-18 labeled annexin V: A potential PET radiopharmaceutical for imaging cell death

Toretsky, J., Levenson, A., Weinberg, I. N., Tait, J. F., Üren, A. & Mease, R. C., Aug 1 2004, In : Nuclear Medicine and Biology. 31, 6, p. 747-752 6 p.

Research output: Contribution to journalArticle

Production and use of cobalt-55 as an antibody label for PET imaging

Srivastava, S. C., Mausner, L. F., Kolsky, K. L., Mease, R. C., Joshi, V., Meinken, G. E., Pyatt, B., Wolf, A. P., Schlyer, D. J., Levy, A. V. & Fowler, J. S., Jan 1 1994, In : Journal of Labelled Compounds and Radiopharmaceuticals. 35, p. 389-391 3 p.

Research output: Contribution to journalArticle

Production of no carrier added 80mBr for investigation of Auger electron toxicity

Mease, R. C., DeJesus, O. T., Gatley, S. J., Harper, P. V., Desombre, E. R. & Friedman, A. M., 1991, In : International Journal of Radiation Applications and Instrumentation. Part. 42, 1, p. 57-61 5 p.

Research output: Contribution to journalArticle

PSMA-Based [18F]DCFPyL PET/CT Is Superior to Conventional Imaging for Lesion Detection in Patients with Metastatic Prostate Cancer

Rowe, S., Macura, K., Mena, E., Blackford, A. L., Nadal, R., Antonarakis, E., Eisenberger, M., Carducci, M. A., Fan, H., Dannals, R. F., Chen, Y., Mease, R., Szabo, Z., Pomper, M. G. & Cho, S. Y., Apr 14 2016, (Accepted/In press) In : Molecular Imaging and Biology. p. 1-9 9 p.

Research output: Contribution to journalArticle

Radiochemical synthesis and in vivo evaluation of [18F]AZ11637326: An agonist probe for the α7 nicotinic acetylcholine receptor

Ravert, H. T., Dorff, P., Foss, C. A., Mease, R. C., Fan, H., Holmquist, C. R., Phillips, E., McCarthy, D. J., Heys, J. R., Holt, D. P., Wang, Y., Endres, C. J., Dannals, R. F. & Pomper, M. G., Aug 1 2013, In : Nuclear Medicine and Biology. 40, 6, p. 731-739 9 p.

Research output: Contribution to journalArticle

Radiohalogenated prostate-specific membrane antigen (PSMA)-based ureas as imaging agents for prostate cancer

Chen, Y., Foss, C. A., Byun, Y., Nimmagadda, S., Pullambhatla, M., Fox, J. J., Castanares, M., Lupold, S. E., Babich, J. W., Mease, R. C. & Pomper, M. G., Dec 25 2008, In : Journal of medicinal chemistry. 51, 24, p. 7933-7943 11 p.

Research output: Contribution to journalArticle

Radioiodinated (aminostyryl)pyridinium (ASP) dyes: New cell membrane probes for labeling mixed leukocytes and lymphocytes for diagnostic imaging

Lambert, C., Mease, R. C., Avren, L., Le, T., Sabet, H. & McAfee, J. G., May 1996, In : Nuclear Medicine and Biology. 23, 4, p. 417-427 11 p.

Research output: Contribution to journalArticle

Radioiodinated DPA-713 imaging correlates with bactericidal activity of tuberculosis treatments in mice

Ordonez, A. A., Pokkali, S., DeMarco, V. P., Klunk, M., Mease, R. C., Foss, C. A., Pomper, M. G. & Jain, S. K., Jan 1 2015, In : Antimicrobial agents and chemotherapy. 59, 1, p. 642-649 8 p.

Research output: Contribution to journalArticle

Radiolabeled small-molecule ligands for prostate-specific membrane antigen: In vivo imaging in experimental models of prostate cancer

Foss, C. A., Mease, R. C., Fan, H., Wang, Y., Ravert, H. T., Dannals, R. F., Olszewski, R. T., Heston, W. D., Kozikowski, A. P. & Pomper, M. G., Jun 1 2005, In : Clinical Cancer Research. 11, 11, p. 4022-4028 7 p.

Research output: Contribution to journalArticle

Radioligand Therapy of Prostate Cancer with a Long-lasting PSMA Targeting Agent 90Y-DOTA-EB-MCG

Wang, Z., Jacobson, O., Tian, R., Mease, R., Kiesewetter, D., Niu, G., Pomper, M. G. & Chen, X., Apr 27 2018, (Accepted/In press) In : Bioconjugate Chemistry.

Research output: Contribution to journalArticle

Radionuclide based imaging of prostate cancer

Mease, R. C., Oct 22 2010, In : Current topics in medicinal chemistry. 10, 16, p. 1600-1616 17 p.

Research output: Contribution to journalArticle

Radiosynthesis and PET Bioimaging of 76Br-Bedaquiline in a Murine Model of Tuberculosis

Ordonez, A. A., Carroll, L. S., Abhishek, S., Mota, F., Ruiz-Bedoya, C. A., Klunk, M. H., Singh, A. K., Freundlich, J. S., Mease, R. C. & Jain, S. K., Jan 1 2019, (Accepted/In press) In : ACS Infectious Diseases.

Research output: Contribution to journalArticle

Real-time, near-infrared fluorescence imaging with an optimized dye/light source/camera combination for surgical guidance of prostate cancer

Neuman, B. P., Eifler, J. B., Castanares, M., Chowdhury, W. H., Chen, Y., Mease, R. C., Ma, R., Mukherjee, A., Lupold, S. E., Pomper, M. G. & Rodriguez, R., Feb 15 2015, In : Clinical Cancer Research. 21, 4, p. 771-780 10 p.

Research output: Contribution to journalArticle

Reduction in non-specific uptake of indium-111 from using semi-rigid cyclohexyl EDTA immunoconjugates

Srivastava, S. C., Mease, R. C., Meinken, G. E., Gestin, J. F., Joshi, V., Pyatt, B., Mausner, L. F. & Chatal, J. F., Jan 1 1994, In : Journal of Labelled Compounds and Radiopharmaceuticals. 35, p. 303-305 3 p.

Research output: Contribution to journalArticle

Strong inhibition of xenografted tumor growth by low-level doses of [32P]ATP

Cheng, Y., Yang, J., Agarwal, R., Green, G. M., Mease, R. C., Pomper, M. G., Meltzer, S. J. & Abraham, J. M., Jun 2011, In : Oncotarget. 2, 6, p. 461-466 6 p.

Research output: Contribution to journalArticle

Open Access

Structural optimization, biological evaluation, and application of peptidomimetic prostate specific antigen inhibitors

Kostova, M. B., Rosen, D. M., Chen, Y., Mease, R. C. & Denmeade, S. R., Jun 13 2013, In : Journal of medicinal chemistry. 56, 11, p. 4224-4235 12 p.

Research output: Contribution to journalArticle

SYnthesis and biological evaluation of low molecular weight fluorescent imaging agents for the prostate-specific membrane antigen

Chen, Y., Pullambhatla, M., Banerjee., S. R., Byun, Y., Stathis, M., Rojas, C., Slusher, B. S., Mease, R. C. & Pomper, M. G., Dec 19 2012, In : Bioconjugate Chemistry. 23, 12, p. 2377-2385 9 p.

Research output: Contribution to journalArticle

Synthesis and biological evaluation of substrate-based imaging agents for the prostate-specific membrane antigen

Byun, Y., Pullambhatla, M., Wang, H., Mease, R. C. & Pomper, M. G., May 1 2013, In : Macromolecular Research. 21, 5, p. 565-573 9 p.

Research output: Contribution to journalArticle

Synthesis and direct estrogen receptor binding affinity of 80mBr-labeled 1,1-bis(p-hydroxyphenyl)-2-bromo-2-phenylethylene

Mease, R. C., DeSombre, E. R. & Hughes, A., Jan 1 1986, In : Journal of Labelled Compounds and Radiopharmaceuticals. 23, 10-12, p. 1397-1399 3 p.

Research output: Contribution to journalArticle

Synthesis and evaluation of technetium-99m- and rhenium-labeled inhibitors of the prostate-specific membrane antigen (PSMA)

Banerjee, S. R., Foss, C. A., Castanares, M., Mease, R. C., Byun, Y., Fox, J. J., Hilton, J., Lupold, S. E., Kozikowski, A. P. & Pomper, M. G., Aug 14 2008, In : Journal of medicinal chemistry. 51, 15, p. 4504-4517 14 p.

Research output: Contribution to journalArticle

Synthesis of [125I]iodoDPA-713: A new probe for imaging inflammation

Wang, H., Pullambhatla, M., Guilarte, T. R., Mease, R. C. & Pomper, M. G., Nov 6 2009, In : Biochemical and Biophysical Research Communications. 389, 1, p. 80-83 4 p.

Research output: Contribution to journalArticle

Synthesis of new CDTA-linker-antibody systems for improved in-vivo distribution of In-111

Mease, R. C., Gestin, J. F., Meinken, G. E. & Srivastava, S. C., Apr 5 1991, In : Journal of Labelled Compounds and Radiopharmaceuticals. 30, p. 196-197 2 p.

Research output: Contribution to journalArticle

The synthesis of non-steroidal estrogen receptor binding compounds labeled with 80mBr

Seevers, R. H., Mease, R. C., Friedman, A. M. & Desombre, E. R., 1986, In : International Journal of Radiation Applications and Instrumentation.. 13, 4, p. 483-495 13 p.

Research output: Contribution to journalArticle

Trypanosoma musculi: Tracking parasites and circulating lymphoid cells in host mice

Albright, J. W., Mease, R. C., Lambert, C. & Albright, J. F., Feb 1999, In : Experimental Parasitology. 91, 2, p. 185-195 11 p.

Research output: Contribution to journalArticle