Ronnie Mease

Associate Professor

1984 …2020

Research output per year

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Research Output

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(2S)-2-(3-(1-carboxy-5-(4-211At-astatobenzamido)pentyl) ureido)-pentanedioic acid for PSMA-targeted α-particle radiopharmaceutical therapy

Kiess, A. P., Minn, I., Vaidyanathan, G., Hobbs, R., Josefsson, N. A. M., Shen, C., Brummet, M. E., Chen, Y., Choi, J., Koumarianou, E., Baidoo, K., Brechbiel, M. W., Mease, R., Sgouros, G., Zalutsky, M. R. & Pomper, M. G., Oct 1 2016, In : Journal of Nuclear Medicine. 57, 10, p. 1569-1575 7 p.

Research output: Contribution to journalArticle

[125I]Iodo-ASEM, a specific in vivo radioligand for α7-nAChR

Gao, Y., Mease, R. C., Olson, T. T., Kellar, K. J., Dannals, R. F., Pomper, M. G. & Horti, A. G., May 1 2015, In : Nuclear Medicine and Biology. 42, 5, p. 488-493 6 p.

Research output: Contribution to journalArticle

[32P]ATP inhibits the growth of xenografted tumors in nude mice

Cheng, Y., Senthamizhchelvan, S., Agarwal, R., Green, G. M., Mease, R. C., Sgouros, G., Huso, D. L., Pomper, M. G., Meltzer, S. J. & Abraham, J. M., May 15 2012, In : Cell Cycle. 11, 10, p. 1878-1882 5 p.

Research output: Contribution to journalArticle

[64Cu]XYIMSR-06: A dual-motif CAIX ligand for PET imaging of clear cell renal cell carcinoma

Minn, I., Koo, S. M., Lee, H. S., Brummet, M., Rowe, S. P., Gorin, M. A., Sysa-Shah, P., Lewis, W. D., Ahn, H. H., Wang, Y., Banerjee, S. R., Mease, R. C., Nimmagadda, S., Allaf, M. E., Pomper, M. G. & Yang, X., Jan 1 2016, In : Oncotarget. 7, 35, p. 56471-56479 9 p.

Research output: Contribution to journalArticle

18F-DCFBC PET/CT for PSMA-based detection and characterization of primary prostate cancer

Rowe, S. P., Gage, K. L., Faraj, S. F., Macura, K. J., Cornish, T. C., Gonzalez-Roibon, N., Guner, G., Munari, E., Partin, A. W., Pavlovich, C. P., Han, M., Carter, H. B., Bivalacqua, T. J., Blackford, A., Holt, D., Dannals, R. F., Netto, G. J., Lodge, M. A., Mease, R. C., Pomper, M. G. & 1 others, Cho, S. Y., Jul 1 2015, In : Journal of Nuclear Medicine. 56, 7, p. 1003-1010 8 p.

Research output: Contribution to journalArticle

18F-DCFBC Prostate-Specific Membrane Antigen-Targeted PET/CT Imaging in Localized Prostate Cancer: Correlation with Multiparametric MRI and Histopathology

Turkbey, B., Mena, E., Lindenberg, L., Adler, S., Bednarova, S., Berman, R., Ton, A. T., McKinney, Y., Eclarinal, P., Hill, C., Afari, G., Bhattacharyya, S., Mease, R., Merino, M. J., Jacobs, P. M., Wood, B. J., Pinto, P. A., Pomper, M. G. & Choyke, P. L., Oct 1 2017, In : Clinical Nuclear Medicine. 42, 10, p. 735-740 6 p.

Research output: Contribution to journalArticle

2-(3-{1-carboxy-5-[(6-[ 18F]fluoro-pyridine-3-carbonyl)-amino]- pentyl}-ureido)-pentanedioic acid, [ 18F]DCFPyL, a PSMA-based PET imaging agent for prostate cancer

Chen, Y., Pullambhatla, M., Foss, C. A., Byun, Y., Nimmagadda, S., Senthamizhchelvan, S., Sgouros, G., Mease, R. C. & Pomper, M. G., Dec 15 2011, In : Clinical Cancer Research. 17, 24, p. 7645-7653 9 p.

Research output: Contribution to journalArticle

64Cu-labeled inhibitors of prostate-specific membrane antigen for PET imaging of prostate cancer

Banerjee, S. R., Pullambhatla, M., Foss, C. A., Nimmagadda, S., Ferdani, R., Anderson, C. J., Mease, R. C. & Pomper, M. G., Mar 27 2014, In : Journal of medicinal chemistry. 57, 6, p. 2657-2669 13 p.

Research output: Contribution to journalArticle

68Ga-labeled inhibitors of prostate-specific membrane antigen (PSMA) for imaging prostate cancer

Banerjee, S. R., Pullambhatla, M., Byun, Y., Nimmagadda, S., Green, G., Fox, J. J., Horti, A., Mease, R. C. & Pomper, M. G., Jul 22 2010, In : Journal of medicinal chemistry. 53, 14, p. 5333-5341 9 p.

Research output: Contribution to journalArticle

A comparison of prostate cancer bone metastases on18F-sodium fluoride and prostate specific membrane antigen (18F-PSMA) PET/CT: Discordant uptake in the same lesion

Harmon, S. A., Mena, E., Shih, J. H., Adler, S., McKinney, Y., Bergvall, E., Mehralivand, S., Sowalsky, A. G., Couvillon, A., Madan, R. A., Gulley, J. L., Eary, J., Mease, R., Pomper, M. G., Dahut, W. L., Turkbey, B., Lindenberg, L. & Choyke, P. L., Dec 1 2018, In : Oncotarget. 9, 102, p. 37676-37688 13 p.

Research output: Contribution to journalArticle

AEG-1 promoter-mediated imaging of prostate cancer

Bhatnagar, A., Wang, Y., Mease, R. C., Gabrielson, M., Sysa, P., Minn, I., Green, G., Simmons, B., Gabrielson, K., Sarkar, S., Fisher, P. B. & Pomper, M. G., Oct 15 2014, In : Cancer Research. 74, 20, p. 5772-5781 10 p.

Research output: Contribution to journalArticle

A low molecular weight PSMA-based fluorescent imaging agent for cancer

Chen, Y., Dhara, S., Banerjee, S. R., Byun, Y., Pullambhatla, M., Mease, R. C. & Pomper, M. G., Dec 18 2009, In : Biochemical and Biophysical Research Communications. 390, 3, p. 624-629 6 p.

Research output: Contribution to journalArticle

A modular strategy to prepare multivalent inhibitors of prostate-specific membrane antigen (PSMA)

Banerjee, S. R., Pullambhatla, M., Shallal, H., Lisok, A., Mease, R. C. & Pomper, M. G., Dec 2011, In : Oncotarget. 2, 12, p. 1244-1253 10 p.

Research output: Contribution to journalArticle

Open Access

A peptide-based 68Ga-PET radiotracer for imaging PD-L1 expression in cancer

De Silva, R., Kumar, D., Lisok, A., Chatterjee, S., Wharram, B., Rao, K. V., Mease, R., Dannals, R. F., Pomper, M. G. & Nimmagadda, S., Apr 16 2018, (Accepted/In press) In : Molecular Pharmaceutics.

Research output: Contribution to journalArticle

A Prospective Comparison of 18F-Sodium Fluoride PET/CT and PSMA-Targeted 18F-DCFBC PET/CT in Metastatic Prostate Cancer

Harmon, S. A., Bergvall, E., Mena, E., Shih, J. H., Adler, S., McKinney, Y., Mehralivand, S., Citrin, D. E., Couvillon, A., Madan, R. A., Gulley, J. L., Mease, R., Jacobs, P. M., Pomper, M. G., Turkbey, B., Choyke, P. L. & Lindenberg, M. L., Nov 1 2018, In : Journal of Nuclear Medicine. 59, 11, p. 1665-1671 7 p.

Research output: Contribution to journalArticle

A PSMA-targeted theranostic agent for photodynamic therapy

Chen, Y., Chatterjee, S., Lisok, A., Minn, I., Pullambhatla, M., Wharram, B., Wang, Y., Jin, J., Bhujwalla, Z. M., Nimmagadda, S., Mease, R. & Pomper, M. G., Feb 1 2017, In : Journal of Photochemistry and Photobiology B: Biology. 167, p. 111-116 6 p.

Research output: Contribution to journalArticle

A red-shifted fluorescent substrate for aldehyde dehydrogenase

Minn, I., Wang, H., Mease, R. C., Byun, Y., Yang, X., Wang, J., Leach, S. D. & Pomper, M. G., Apr 23 2014, In : Nature communications. 5, 3662.

Research output: Contribution to journalArticle

Auger radiopharmaceutical therapy targeting prostate-specific membrane antigen

Kiess, A. P., Minn, I., Chen, Y., Hobbs, R., Sgouros, G., Mease, R. C., Pullambhatla, M., Shen, C. J., Foss, C. A. & Pomper, M. G., Sep 1 2015, In : Journal of Nuclear Medicine. 56, 9, p. 1401-1407 7 p.

Research output: Contribution to journalArticle

Biodistribution, tumor detection, and radiation dosimetry of 18F-DCFBC, a low-molecular-weight inhibitor of prostate-specific membrane antigen, in patients with metastatic prostate cancer

Cho, S. Y., Gage, K. L., Mease, R. C., Senthamizhchelvan, S., Holt, D. P., Jeffrey-Kwanisai, A., Endres, C. J., Dannals, R. F., Sgouros, G., Lodge, M., Eisenberger, M. A., Rodriguez, R., Carducci, M. A., Rojas, C., Slusher, B. S., Kozikowski, A. P. & Pomper, M. G., Dec 1 2012, In : Journal of Nuclear Medicine. 53, 12, p. 1883-1891 9 p.

Research output: Contribution to journalArticle

Bioisosterism of urea-based GCPII inhibitors: Synthesis and structure-activity relationship studies

Wang, H., Byun, Y., Barinka, C., Pullambhatla, M., Bhang, H. E. C., Fox, J. J., Lubkowski, J., Mease, R. C. & Pomper, M. G., Jan 1 2010, In : Bioorganic and Medicinal Chemistry Letters. 20, 1, p. 392-397 6 p.

Research output: Contribution to journalArticle

Bridged cyclams as imaging agents for chemokine receptor 4 (CXCR4)

Woodard, L. E., De Silva, R. A., Behnam Azad, B., Lisok, A., Pullambhatla, M., Lesniak, W. G., Mease, R. C., Pomper, M. G. & Nimmagadda, S., Aug 2014, In : Nuclear Medicine and Biology. 41, 7, p. 552-561 10 p.

Research output: Contribution to journalArticle

Bromine-80m-labeled Estrogens: Auger Electron-emitting, Estrogen Receptor-directed Ligands with Potential for Therapy of Estrogen Receptor-positive Cancers

DeSombre, E. R., Mease, R. C., Hughes, A., Harper, P. V., DeJesus, O. T. & Friedman, A. M., Jan 1 1988, In : Cancer Research. 48, 4, p. 899-906 8 p.

Research output: Contribution to journalArticle

Bromine-80m radiotoxicity and the potential for estrogen receptor-directed therapy with auger electrons

DeSombre, E. R., Harper, P. V., Hughes, A., Gatley, S. J., Schwartz, J. L., DeJesus, O. T. & Mease, R. C., Oct 1988, In : Cancer Research. 48, 20, p. 5805-5809 5 p.

Research output: Contribution to journalArticle

Clinical impact of PSMA-based 18F–DCFBC PET/CT imaging in patients with biochemically recurrent prostate cancer after primary local therapy

Mena, E., Lindenberg, M. L., Shih, J. H., Adler, S., Harmon, S., Bergvall, E., Citrin, D., Dahut, W., Ton, A. T., McKinney, Y., Weaver, J., Eclarinal, P., Forest, A., Afari, G., Bhattacharyya, S., Mease, R., Merino, M. J., Pinto, P., Wood, B. J., Jacobs, P. & 3 others, Pomper, M. G., Choyke, P. L. & Turkbey, B., Sep 11 2017, (Accepted/In press) In : European Journal of Nuclear Medicine and Molecular Imaging. p. 1-8 8 p.

Research output: Contribution to journalArticle

Comparison of the distribution of bromine-77-bromovinyl steroidal and triphenylethylene estrogens in the immature rat

DeSombre, E. R., Hughes, A., Mease, R. C. & Harper, P. V., Jan 1 1990, In : Journal of Nuclear Medicine. 31, 9, p. 1534-1542 9 p.

Research output: Contribution to journalArticle

Development and evaluation of copper-67 and samarium-153 labeled conjugates for tumor radioimmunotherapy

Srivastava, S. C., Mausner, L. F., Mease, R. C., Meinken, G. E., Joshi, V., Kolsky, K., Sweet, M. & Steplewski, Z., Jan 1 1995, In : International Journal of Pharmacognosy. 33, SUPPL., p. 92-101 10 p.

Research output: Contribution to journalArticle

Development and evaluation of copper-67 and samarium-153 labeled conjugates for tumor radioimmunotherapy

Srivastava, S. S., Mausner, L. L., Mease, R. R., Meinken, G. G., Joshi, V., Kolsky, K., Sweet, M. & Steplewski, Z., Jan 1 1995, In : Pharmaceutical Biology. 33, S1, p. 92-101 10 p.

Research output: Contribution to journalArticle

Development and evaluation of copper-67 labeled DOTA and TETA immunoconjugates for radioimmunotherapy

Mausner, L. F., Srivastava, S. C., Kolsky, K. L., Mease, R. C., Joshi, V., Meinken, G. E., Kurczak, S., Chatal, J. F. & Steplewski, Z., Jan 1 1994, In : Journal of Labelled Compounds and Radiopharmaceuticals. 35, p. 374-376 3 p.

Research output: Contribution to journalArticle

Development of [18F]FPy-WL12 as a PD-L1 Specific PET Imaging Peptide

Lesniak, W. G., Mease, R. C., Chatterjee, S., Kumar, D., Lisok, A., Wharram, B., Kalagadda, V. R., Emens, L. A., Pomper, M. G. & Nimmagadda, S., Jun 11 2019, In : Molecular imaging. 18

Research output: Contribution to journalArticle

Open Access

Development of a new radiolabel (203Pb) and new chelating agents for labeling monoclonal antibodies for imaging.

Srivastava, S. C., Mease, R. C., Meinken, G. E., Mausner, L. F. & Steplewski, Z., 1990, In : Acta radiologica. Supplementum. 374, p. 135-140 6 p.

Research output: Contribution to journalArticle

Development of Radiolabeled Ligands Targeting the Glutamate Binding Site of the N-Methyl-d-aspartate Receptor as Potential Imaging Agents for Brain

Tamborini, L., Chen, Y., Foss, C., Pinto, A., Horti, A., Traynelis, S. F., De Micheli, C., Mease, R., Hansen, K. B., Conti, P. & Pomper, M. G., Dec 22 2016, In : Journal of Medicinal Chemistry. 59, 24, p. 11110-11119 10 p.

Research output: Contribution to journalArticle

Effect of chelate rigidity on in vivo radioimmunoconjugate distribution

Mease, R. C., Srivastava, S. C., Lambert, C., Meinken, G. E. & Steplewski, Z., Apr 5 1991, In : Journal of Labelled Compounds and Radiopharmaceuticals. 30, p. 319-321 3 p.

Research output: Contribution to journalArticle

Effects of aging on the dynamics of lymphocyte organ distribution in mice: Use of a radioiodinated cell membrane probe

Albright, J. W., Mease, R. C., Lambert, C. & Albright, J. F., Apr 1 1998, In : Mechanisms of Ageing and Development. 101, 3, p. 197-211 15 p.

Research output: Contribution to journalArticle

Estrogen receptor binding affinity and uterotrophic activity of triphenylhaloethylenes

DeSombre, E. R., Mease, R. C., Sanghavl, J., Singh, T., Seevers, R. H. & Hughes, A., Jun 1988, In : Journal of Steroid Biochemistry. 29, 6, p. 583-590 8 p.

Research output: Contribution to journalArticle

Evaluation of prostate-specific membrane antigen as an imaging reporter

Castanares, M. A., Mukherjee, A., Chowdhury, W. H., Liu, M., Chen, Y., Mease, R. C., Wang, Y., Rodriguez, R., Lupold, S. E. & Pomper, M. G., May 1 2014, In : Journal of Nuclear Medicine. 55, 5, p. 805-811 7 p.

Research output: Contribution to journalArticle

Fluorobenzoyllysinepentanedioic Acid Carbamates: New Scaffolds for Positron Emission Tomography (PET) Imaging of Prostate-Specific Membrane Antigen (PSMA)

Yang, X., Mease, R. C., Pullambhatla, M., Lisok, A., Chen, Y., Foss, C. A., Wang, Y., Shallal, H., Edelman, H., Hoye, A. T., Attardo, G., Nimmagadda, S. & Pomper, M. G., Jan 14 2016, In : Journal of medicinal chemistry. 59, 1, p. 206-218 13 p.

Research output: Contribution to journalArticle

Fluoroethyl Triazole Substituted PSMA Inhibitor Exhibiting Rapid Normal Organ Clearance

Chen, Y., Lisok, A., Chatterjee, S., Wharram, B., Pullambhatla, M., Wang, Y., Sgouros, G., Mease, R. & Pomper, M. G., Jul 20 2016, In : Bioconjugate Chemistry. 27, 7, p. 1655-1662 8 p.

Research output: Contribution to journalArticle

Heterobivalent agents targeting PSMA and integrin- αvβ3

Shallal, H. M., Minn, I., Banerjee, S. R., Lisok, A., Mease, R. C. & Pomper, M. G., Feb 19 2014, In : Bioconjugate Chemistry. 25, 2, p. 393-405 13 p.

Research output: Contribution to journalArticle

High-throughput screen identifies novel inhibitors of cancer biomarker α-methylacyl coenzyme A racemase (AMACR/P504S)

Wilson, B. A. P., Wang, H., Nacev, B. A., Mease, R. C., Liu, J. O., Pomper, M. G. & Isaacs, W. B., May 1 2011, In : Molecular cancer therapeutics. 10, 5, p. 825-838 14 p.

Research output: Contribution to journalArticle

Imaging enterobacteriaceae infection in vivo with 18F-fluorodeoxysorbitol positron emission tomography

Weinstein, E. A., Ordonez, A. A., DeMarco, V. P., Murawski, A. M., Pokkali, S., MacDonald, E. M., Klunk, M., Mease, R. C., Pomper, M. G. & Jain, S. K., Oct 22 2014, In : Science translational medicine. 6, 259, p. 259ra146

Research output: Contribution to journalArticle

Imaging of carbonic anhydrase IX with an 111In-labeled dual-motif inhibitor

Yang, X., Minn, I., Rowe, S. P., Banerjee, S. R., Gorin, M. A., Brummet, M., Lee, H. S., Koo, S. M., Sysa-Shah, P., Mease, R. C., Nimmagadda, S., Allaf, M. E. & Pomper, M. G., Jan 1 2015, In : Oncotarget. 6, 32, p. 33733-33742 10 p.

Research output: Contribution to journalArticle

Improved syntheses of precursors for PET radioligands [18F]XTRA and [18F]AZAN

Gao, Y., Wang, H., Mease, R. C., Pomper, M. G. & Horti, A. G., Oct 6 2010, In : Tetrahedron Letters. 51, 40, p. 5333-5335 3 p.

Research output: Contribution to journalArticle

Initial Evaluation of [18F]DCFPyL for Prostate-Specific Membrane Antigen (PSMA)-Targeted PET Imaging of Prostate Cancer

Szabo, Z., Mena, E., Rowe, S. P., Plyku, D., Nidal, R., Eisenberger, M. A., Antonarakis, E. S., Fan, H., Dannals, R. F., Chen, Y., Mease, R. C., Vranesic, M., Bhatnagar, A., Sgouros, G., Cho, S. Y. & Pomper, M. G., Aug 23 2015, In : Molecular Imaging and Biology. 17, 4, p. 565-574 10 p.

Research output: Contribution to journalArticle

Interactions between human glutamate carboxypeptidase II and urea-based inhibitors: Structural characterization

Barinka, C., Byun, Y., Dusich, C. L., Banerjee, S. R., Chen, Y., Castanares, M., Kozikowski, A. P., Mease, R. C., Pomper, M. G. & Lubkowski, J., Dec 25 2008, In : Journal of medicinal chemistry. 51, 24, p. 7737-7743 7 p.

Research output: Contribution to journalArticle