Roland R Griffiths

Professor

1969 …2020
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Research Output 1969 2020

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Article
2020
Hallucinogens
anxiety
flexibility
Anxiety
Depression
2019

A randomized controlled trial of a manual-only treatment for reduction and cessation of problematic caffeine use

Sweeney, M., Meredith, S. E., Juliano, L. M., Evatt, D. P. & Griffiths, R. R., Feb 1 2019, In : Drug and Alcohol Dependence. 195, p. 45-51 7 p.

Research output: Contribution to journalArticle

Withholding Treatment
Caffeine
Randomized Controlled Trials
Therapeutics

Cessation and reduction in alcohol consumption and misuse after psychedelic use

Garcia-Romeu, A., Davis, A. K., Erowid, F., Erowid, E., Griffiths, R. R. & Johnson, M. W., Jan 1 2019, In : Journal of Psychopharmacology.

Research output: Contribution to journalArticle

Hallucinogens
Alcohol Drinking
Alcohols
Lysergic Acid Diethylamide
Psilocybin
Hallucinogens
Epidemiology
Brain
Therapeutics
Psychology
2018
Methoxydimethyltryptamines
Anxiety
Depression
Clinical Trials
Hallucinogens

Double-blind comparison of the two hallucinogens psilocybin and dextromethorphan: effects on cognition

Barrett, F., Carbonaro, T. M., Hurwitz, E., Johnson, M. W. & Griffiths, R. R., Jan 1 2018, (Accepted/In press) In : Psychopharmacology.

Research output: Contribution to journalArticle

Psilocybin
Dextromethorphan
Hallucinogens
Cognition
Psychomotor Performance

Intensity of mystical experiences occasioned by 5-MeO-DMT and comparison with a prior psilocybin study

Barsuglia, J., Davis, A. K., Palmer, R., Lancelotta, R., Windham-Herman, A. M., Peterson, K., Polanco, M., Grant, R. & Griffiths, R. R., Dec 6 2018, In : Frontiers in Psychology. 9, DEC, 2459.

Research output: Contribution to journalArticle

Psilocybin
Anura
Bufonidae
Hallucinogens
Mexico
Psilocybin
Meditation
Psychology
Forgiveness
Healthy Volunteers

Psychedelic therapy for smoking cessation: Qualitative analysis of participant accounts

Noorani, T., Garcia-Romeu, A., Swift, T. C., Griffiths, R. R. & Johnson, M. W., Jul 1 2018, In : Journal of Psychopharmacology. 32, 7, p. 756-769 14 p.

Research output: Contribution to journalArticle

Psilocybin
Hallucinogens
Smoking Cessation
Interviews
Altruism
2017

Double-blind comparison of the two hallucinogens psilocybin and dextromethorphan: similarities and differences in subjective experiences

Carbonaro, T. M., Johnson, M. W., Hurwitz, E. & Griffiths, R. R., Nov 7 2017, (Accepted/In press) In : Psychopharmacology. p. 1-14 14 p.

Research output: Contribution to journalArticle

Psilocybin
Dextromethorphan
Hallucinogens
Pharmaceutical Preparations
Blood Pressure

Effects of caffeine on alcohol reinforcement: beverage choice, self-administration, and subjective ratings

Sweeney, M., Meredith, S. E., Evatt, D. P. & Griffiths, R. R., Mar 1 2017, In : Psychopharmacology. 234, 5, p. 877-888 12 p.

Research output: Contribution to journalArticle

Self Administration
Beverages
Caffeine
Alcohols
Alcohol Drinking
Psilocybin
Hallucinogens
Agaricales
Paranoid Disorders
Lysergic Acid Diethylamide

Qualitative and quantitative features of music reported to support peak mystical experiences during psychedelic therapy sessions

Barrett, F., Robbins, H., Smooke, D., Brown, J. L. & Griffiths, R. R., Jul 25 2017, In : Frontiers in Physiology. 8, JUL, 1238.

Research output: Contribution to journalArticle

Hallucinogens
Music
Psilocybin
Therapeutics
Pharmaceutical Preparations
2016

A brief manualized treatment for problematic caffeine use: A randomized control trial

Evatt, D. P., Juliano, L. M. & Griffiths, R. R., Feb 1 2016, In : Journal of Consulting and Clinical Psychology. 84, 2, p. 113-121 9 p.

Research output: Contribution to journalArticle

Caffeine
Therapeutics
Pamphlets
Research Personnel
Interviews

Long-term follow-up of psilocybin-facilitated smoking cessation

Johnson, M. W., Garcia-Romeu, A. & Griffiths, R. R., Jul 23 2016, (Accepted/In press) In : American Journal of Drug and Alcohol Abuse. p. 1-6 6 p.

Research output: Contribution to journalArticle

Psilocybin
Smoking Cessation
Smoking
Cognitive Therapy
Hallucinogens

Naltrexone but Not Ketanserin Antagonizes the Subjective, Cardiovascular, and Neuroendocrine Effects of Salvinorin-A in Humans

Maqueda, A. E., Valle, M., Addy, P. H., Antonijoan, R. M., Puntes, M., Coimbra, J., Ballester, M. R., Garrido, M., González, M., Claramunt, J., Barker, S., Lomnicka, I., Waguespack, M., Johnson, M. W., Griffiths, R. R. & Riba, J., Jul 1 2016, In : The international journal of neuropsychopharmacology. 19, 7

Research output: Contribution to journalArticle

salvinorin A
Ketanserin
Naltrexone
Placebos
kappa Opioid Receptor

Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial

Griffiths, R. R., Johnson, M. W., Carducci, M. A., Umbricht, A., Richards, W. A., Richards, B. D., Cosimano, M. P. & Klinedinst, M. A., Dec 1 2016, In : Journal of Psychopharmacology. 30, 12, p. 1181-1197 17 p.

Research output: Contribution to journalArticle

Psilocybin
Anxiety
Depression
Neoplasms
Spirituality

Survey study of challenging experiences after ingesting psilocybin mushrooms: Acute and enduring positive and negative consequences

Carbonaro, T. M., Bradstreet, M. P., Barrett, F., MacLean, K. A., Jesse, R., Johnson, M. W. & Griffiths, R. R., Dec 1 2016, In : Journal of Psychopharmacology. 30, 12, p. 1268-1278 11 p.

Research output: Contribution to journalArticle

Psilocybin
Agaricales
Psychology
Attempted Suicide
Social Support
Psilocybin
Agaricales
Hallucinogens
Consciousness
Paranoid Disorders

Time course of pharmacokinetic and hormonal effects of inhaled high-dose salvinorin A in humans

Johnson, M. W., MacLean, K. A., Caspers, M. J., Prisinzano, T. E. & Griffiths, R. R., Apr 1 2016, In : Journal of Psychopharmacology. 30, 4, p. 323-329 7 p.

Research output: Contribution to journalArticle

salvinorin A
Pharmacokinetics
Inhalation
Pharmaceutical Preparations
Salvia
2015

Inhaled vs. oral alprazolam: Subjective, behavioral and cognitive effects, and modestly increased abuse potential

Reissig, C. J., Harrison, J. A., Carter, L. P. & Griffiths, R. R., 2015, In : Psychopharmacology. 232, 5, p. 871-883 13 p.

Research output: Contribution to journalArticle

Alprazolam
Pharmaceutical Preparations
Cross-Over Studies
Inhalation
Substance-Related Disorders

Nicotine reinforcement in never-smokers

Duke, A. N., Johnson, M. W., Reissig, C. J. & Griffiths, R. R., Sep 8 2015, In : Psychopharmacology. 232, 23, p. 4243-4252 10 p.

Research output: Contribution to journalArticle

Nicotine
Tobacco Use
Tobacco
Mortality
Reinforcement (Psychology)

Psilocybin, psychological distress, and suicidality

Hendricks, P. S., Johnson, M. W. & Griffiths, R. R., Sep 23 2015, In : Journal of Psychopharmacology. 29, 9, p. 1041-1043 3 p.

Research output: Contribution to journalArticle

Psilocybin
Hallucinogens
Psychological Stress
Suicide
Mental Health

Salvinorin-A induces intense dissociative effects, blocking external sensory perception and modulating interoception and sense of body ownership in humans

Maqueda, A. E., Valle, M., Addy, P. H., Antonijoan, R. M., Puntes, M., Coimbra, J., Ballester, M. R., Garrido, M., González, M., Claramunt, J., Barker, S., Johnson, M. W., Griffiths, R. R. & Riba, J., 2015, In : International Journal of Neuropsychopharmacology. 18, 12, p. 1-14 14 p.

Research output: Contribution to journalArticle

salvinorin A
Ownership
Hallucinogens
kappa Opioid Receptor
Healthy Volunteers
Psilocybin
Agaricales
Structural Models
Reproducibility of Results
Statistical Factor Analysis
2014

Pilot study of the 5-HT2AR agonist psilocybin in the treatment of tobacco addiction

Johnson, M. W., Garcia-Romeu, A., Cosimano, M. P. & Griffiths, R. R., 2014, In : Journal of Psychopharmacology. 28, 11, p. 983-992 10 p.

Research output: Contribution to journalArticle

Psilocybin
Tobacco
Smoking Cessation
Smoking
Withholding Treatment
Psilocybin
Tobacco
Smoking Cessation
Smoking
Therapeutics
2013

Acute cognitive effects of high doses of dextromethorphan relative to triazolam in humans

Carter, L. P., Reissig, C. J., Johnson, M. W., Klinedinst, M. A., Griffiths, R. R. & Mintzer, M. Z., 2013, In : Drug and Alcohol Dependence. 128, 3, p. 206-213 8 p.

Research output: Contribution to journalArticle

Triazolam
Dextromethorphan
Placebos
Hallucinogens
Data storage equipment

Cognitive effects of intramuscular ketamine and oral triazolam in healthy volunteers

Carter, L. P., Kleykamp, B. A., Griffiths, R. R. & Mintzer, M. Z., Mar 2013, In : Psychopharmacology. 226, 1, p. 53-63 11 p.

Research output: Contribution to journalArticle

Triazolam
Ketamine
Healthy Volunteers
Episodic Memory
Short-Term Memory

Comparative abuse liability of GHB and ethanol in humans

Johnson, M. W. & Griffiths, R. R., Apr 2013, In : Experimental and Clinical Psychopharmacology. 21, 2, p. 112-123 12 p.

Research output: Contribution to journalArticle

Ethanol
Pharmaceutical Preparations
Hypnotics and Sedatives
Placebos
Sodium Oxybate

Corrigendum to Acute cognitive effects of high doses of dextromethorphan relative to triazolam in humans [Drug Alcohol Depend. 128 (2013) 206-213]

Carter, L. P., Reissig, C. J., Johnson, M. W., Klinedinst, M. A., Griffiths, R. R. & Mintzer, M. Z., Nov 1 2013, In : Drug and Alcohol Dependence. 133, 1, p. 294 1 p.

Research output: Contribution to journalArticle

Triazolam
Dextromethorphan
Alcohols
Pharmaceutical Preparations
corrigendum

Dose-related effects of salvinorin A in humans: Dissociative, hallucinogenic, and memory effects

MacLean, K. A., Johnson, M. W., Reissig, C. J., Prisinzano, T. E. & Griffiths, R. R., Mar 2013, In : Psychopharmacology. 226, 2, p. 381-392 12 p.

Research output: Contribution to journalArticle

salvinorin A
Hallucinogens
Opioid Analgesics
Salvia
Neurobiology

Erratum: High doses of dextromethorphan, an NMDA antagonist, produce effects similar to classic hallucinogens (Psychopharmacology DOI 10.1007/s00213-012-2680-6)

Reissig, C. J., Carter, L. P., Johnson, M. W., Mintzer, M. Z., Klinedinst, M. A. & Griffiths, R. R., Aug 2013, In : Psychopharmacology. 228, 3, p. 513 1 p.

Research output: Contribution to journalArticle

Dextromethorphan
Hallucinogens
Psychopharmacology
N-Methylaspartate

LC-MS/MS quantification of salvinorin A from biological fluids

Caspers, M. J., Williams, T. D., Lovell, K. M., Lozama, A., Butelman, E. R., Kreek, M. J., Johnson, M. W., Griffiths, R. R., MacLean, K. & Prisinzano, T. E., 2013, In : Analytical Methods. 5, 24, p. 7042-7048 7 p.

Research output: Contribution to journalArticle

salvinorin A
Cerebrospinal fluid
Plasmas
Fluids
Plasma (human)
2012
Sleep
Episodic Memory
Sleep Initiation and Maintenance Disorders
Short-Term Memory
Healthy Volunteers

Characterization of individuals seeking treatment for caffeine dependence

Juliano, L. M., Evatt, D. P., Richards, B. D. & Griffiths, R. R., Dec 2012, In : Psychology of Addictive Behaviors. 26, 4, p. 948-954 7 p.

Research output: Contribution to journalArticle

Caffeine
Therapeutics
Diagnostic and Statistical Manual of Mental Disorders
Substance-Related Disorders
Psychology
Hallucinogens
Questionnaire
Factor Analysis
Mystical Experience
Mysticism

High doses of dextromethorphan, an NMDA antagonist, produce effects similar to classic hallucinogens

Reissig, C. J., Carter, L. P., Johnson, M. W., Mintzer, M. Z., Klinedinst, M. A. & Griffiths, R. R., Sep 2012, In : Psychopharmacology. 223, 1, p. 1-15 15 p.

Research output: Contribution to journalArticle

Dextromethorphan
Hallucinogens
N-Methylaspartate
Triazolam
Psilocybin

Psilocybin dose-dependently causes delayed, transient headaches in healthy volunteers

Johnson, M. W., Andrew Sewell, R. & Griffiths, R. R., Jun 1 2012, In : Drug and Alcohol Dependence. 123, 1-3, p. 132-140 9 p.

Research output: Contribution to journalArticle

Psilocybin
Headache
Healthy Volunteers
Hallucinogens
Cluster Headache
2011

Caffeine choice prospectively predicts positive subjective effects of caffeine and d-amphetamine

Sigmon, S. C. & Griffiths, R. R., Nov 1 2011, In : Drug and Alcohol Dependence. 118, 2-3, p. 341-348 8 p.

Research output: Contribution to journalArticle

Dextroamphetamine
Caffeine
Placebos
Individuality
Reinforcement

Energy Drink Consumption and Increased Risk for Alcohol Dependence

Arria, A. M., Caldeira, K. M., Kasperski, S. J., Vincent, K. B., Griffiths, R. R. & O'Grady, K. E., Feb 2011, In : Alcoholism: Clinical and Experimental Research. 35, 2, p. 365-375 11 p.

Research output: Contribution to journalArticle

Energy Drinks
Alcoholism
Alcohols
Students
Alcohol Drinking

Human psychopharmacology and dose-effects of salvinorin A, a kappa opioid agonist hallucinogen present in the plant Salvia divinorum

Johnson, M. W., MacLean, K. A., Reissig, C. J., Prisinzano, T. E. & Griffiths, R. R., May 1 2011, In : Drug and Alcohol Dependence. 115, 1-2, p. 150-155 6 p.

Research output: Contribution to journalArticle

salvinorin A
Salvia
Hallucinogens
Psychopharmacology
Opioid Analgesics

Intravenous self-administration of gamma-hydroxybutyrate (GHB) in baboons

Goodwin, A. K., Kaminski, B. J., Griffiths, R. R., Ator, N. A. & Weerts, E., Apr 1 2011, In : Drug and Alcohol Dependence. 114, 2-3, p. 217-224 8 p.

Research output: Contribution to journalArticle

Sodium Oxybate
Self Administration
Papio
Intravenous Administration
Injections
Psilocybin
Hallucinogens
Personality
Imagination
Creativity

Psilocybin occasioned mystical-type experiences: Immediate and persisting dose-related effects

Griffiths, R. R., Johnson, M. W., Richards, W. A., Richards, B. D., McCann, U. D. & Jesse, R., Dec 2011, In : Psychopharmacology. 218, 4, p. 649-665 17 p.

Research output: Contribution to journalArticle

Psilocybin
Volunteers
Hallucinogens
Double-Blind Method
Fear
2010

Dose Effects of Triazolam and Alcohol on Cognitive Performance in Healthy Volunteers

Kleykamp, B. A., Griffiths, R. R. & Mintzer, M. Z., Feb 2010, In : Experimental and Clinical Psychopharmacology. 18, 1, p. 1-16 16 p.

Research output: Contribution to journalArticle

Triazolam
Healthy Volunteers
Alcohols
Benzodiazepines
Psychomotor Disorders

Dose Effects of Triazolam and Scopolamine on Metamemory

Mintzer, M. Z., Kleykamp, B. A. & Griffiths, R. R., Feb 2010, In : Experimental and Clinical Psychopharmacology. 18, 1, p. 17-31 15 p.

Research output: Contribution to journalArticle

Triazolam
Scopolamine Hydrobromide
Episodic Memory
Semantics
Amnesia
Caffeine
Nicotine
Cocaine
Volunteers
Research

Hallucinogens as medicine

Griffiths, R. R. & Grob, C. S., Dec 2010, In : Scientific American. 303, 6, p. 77-79 3 p.

Research output: Contribution to journalArticle

Psilocybin
Hallucinogens
Psychopharmacology
Mental Disorders
Medicine

Increased alcohol consumption, nonmedical prescription drug use, and illicit drug use are associated with energy drink consumption among college students

Arria, A. M., Caldeira, K. M., Kasperski, S. J., O-Grady, K. E., Vincent, K. B., Griffiths, R. R. & Wish, E. D., Jun 2010, In : Journal of Addiction Medicine. 4, 2, p. 74-80 7 p.

Research output: Contribution to journalArticle

Energy Drinks
Prescription Drugs
Street Drugs
Alcohol Drinking
Students