Research output per year
Research output per year
- 1 - 50 out of 172 results
Search results
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2024
The role of N-terminal phosphorylation of DGK-θ
Barbernitz, M. X., Devine, L. R., Cole, R. & Raben, D. M., Mar 2024, In: Journal of Lipid Research. 65, 3, 100506.Research output: Contribution to journal › Article › peer-review
Open Access -
2023
A cell-free antigen processing system informs HIV-1 epitope selection and vaccine design
Sengupta, S., Zhang, J., Reed, M. C., Yu, J., Kim, A., Boronina, T. N., Board, N. L., Wrabl, J. O., Shenderov, K., Welsh, R. A., Yang, W., Timmons, A. E., Hoh, R., Cole, R. N., Deeks, S. G., Siliciano, J. D., Siliciano, R. F. & Sadegh-Nasseri, S., Jul 3 2023, In: Journal of Experimental Medicine. 220, 7, e20221654.Research output: Contribution to journal › Article › peer-review
Open Access -
Arginine methylation of RNA-binding proteins is impaired in Huntington's disease
Ratovitski, T., Kamath, S. V., O'Meally, R. N., Gosala, K., Holland, C. D., Jiang, M., Cole, R. N. & Ross, C. A., Oct 15 2023, In: Human molecular genetics. 32, 20, p. 3006-3025 20 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Atp7b-dependent choroid plexus dysfunction causes transient copper deficit and metabolic changes in the developing mouse brain
Washington-Hughes, C. L., Roy, S., Seneviratne, H. K., Karuppagounder, S. S., Morel, Y., Jones, J. W., Zak, A., Xiao, T., Boronina, T. N., Cole, R. N., Bumpus, N. N., Chang, C. J., Dawson, T. M. & Lutsenko, S., Jan 10 2023, In: PLoS genetics. 19, 1, e1010558.Research output: Contribution to journal › Article › peer-review
Open Access -
Cottonseed hydrolysate supplementation alters metabolic and proteomics responses in Chinese hamster ovary cell cultures
Dhara, V. G., Kumar, S., DeVine, L., Naik, H. M., Cole, R. N., More, A. J., Lau, E. C. & Betenbaugh, M. J., Jun 2023, In: Biotechnology Journal. 18, 6, 2200243.Research output: Contribution to journal › Article › peer-review
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Differential Detection of O-GlcNAcylated proteins in the heart using antibodies
Narayanan, B., Zahra, F., Reeves, R. A., Aggarwal, A., O'Meally, R. N., Henry, R. K., Craven, M., Jacobson, A., Cole, R. N., Kohr, M. J., Umapathi, P. & Zachara, N. E., Oct 1 2023, In: Analytical biochemistry. 678, 115262.Research output: Contribution to journal › Article › peer-review
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Global Discovery and Temporal Changes of Human Albumin Modifications by Pan-Protein Adductomics: Initial Application to Air Pollution Exposure
Smith, J. W., O’Meally, R. N., Burke, S. M., Ng, D. K., Chen, J. G., Kensler, T. W., Groopman, J. D. & Cole, R. N., Apr 5 2023, In: Journal of the American Society for Mass Spectrometry. 34, 4, p. 595-607 13 p.Research output: Contribution to journal › Article › peer-review
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Native lamin A/C proteomes and novel partners from heart and skeletal muscle in a mouse chronic inflammation model of human frailty
Elzamzami, F. D., Samal, A., Arun, A. S., Dharmaraj, T., Prasad, N. R., Rendon-Jonguitud, A., DeVine, L., Walston, J. D., Cole, R. N. & Wilson, K. L., 2023, In: Frontiers in Cell and Developmental Biology. 11, 1240285.Research output: Contribution to journal › Article › peer-review
Open Access -
Plasma proteomic analysis on neuropathic pain in idiopathic peripheral neuropathy patients
van Doormaal, P. T. C., Thomas, S., Ajroud-Driss, S., Cole, R. N., DeVine, L. R., Dimachkie, M. M., Geisler, S., Freeman, R., Simpson, D. M., Singleton, J. R., Smith, A. G., Stino, A. & Höke, A., 2023, (Accepted/In press) In: Journal of the Peripheral Nervous System.Research output: Contribution to journal › Article › peer-review
Open Access -
The C-Terminal of NaV1.7 Is Ubiquitinated by NEDD4L
Wright, K. M., Jiang, H., Xia, W., Murphy, M. B., Boronina, T. N., Nwafor, J. N., Kim, H. J., Iheanacho, A. M., Azurmendi, P. A., Cole, R. N., Cole, P. A. & Gabelli, S. B., Dec 20 2023, In: ACS Bio and Med Chem Au. 3, 6, p. 516-527 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
The Interaction of Borrelia burgdorferi with Human Dendritic Cells: Functional Implications
Gutierrez-Hoffmann, M., Fan, J., O'Meally, R. N., Cole, R. N., Florea, L., Antonescu, C., Talbot, C. C., Tiniakou, E., Darrah, E. & Soloski, M. J., Aug 1 2023, In: Journal of Immunology. 211, 4, p. 612-625 14 p.Research output: Contribution to journal › Article › peer-review
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α-lipoic acid ameliorates consequences of copper overload by up-regulating selenoproteins and decreasing redox misbalance
Kabin, E., Dong, Y., Roy, S., Smirnova, J., Smith, J., Ralle, M., Summers, K., Yang, H., Dev, S., Wang, Y., Devenney, B., Cole, R. N., Palumaa, P. & Lutsenko, S., 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 40, e2305961120.Research output: Contribution to journal › Article › peer-review
Open Access -
2022
A proteomics approach to decipher a sticky CHO situation
Kumar, S., Kumar, A., Huhn, S., DeVine, L., Cole, R., Du, Z. & Betenbaugh, M., Aug 2022, In: Biotechnology and bioengineering. 119, 8, p. 2064-2075 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
A versatile design platform for glycoengineering therapeutic antibodies
Ludwig, S. D., Bernstein, Z. J., Agatemor, C., Dammen-Brower, K., Ruffolo, J., Rosas, J. M., Post, J. D., Cole, R. N., Yarema, K. J. & Spangler, J. B., 2022, In: mAbs. 14, 1, 2095704.Research output: Contribution to journal › Article › peer-review
Open Access -
Comparative systeomics to elucidate physiological differences between CHO and SP2/0 cell lines
Demirhan, D., Kumar, A., Zhu, J., Poulsen, P. C., Majewska, N. I., Sebastian, Y., Chaerkady, R., Yu, W., Zhu, W., Zhuang, L., Shah, P., Lekstrom, K., Cole, R. N., Zhang, H., Betenbaugh, M. J. & Bowen, M. A., Dec 2022, In: Scientific reports. 12, 1, 3280.Research output: Contribution to journal › Article › peer-review
Open Access -
De novo methylation of histone H3K23 by the methyltransferases EHMT1/GLP and EHMT2/G9a
Vinson, D. A., Stephens, K. E., O’Meally, R. N., Bhat, S., Dancy, B. C. R., Cole, R. N., Yegnasubramanian, S. & Taverna, S. D., Dec 2022, In: Epigenetics and Chromatin. 15, 1, 36.Research output: Contribution to journal › Article › peer-review
Open Access -
Hepatic Steatosis in the Mouse Model of Wilson Disease Coincides with a Muted Inflammatory Response
Gottlieb, A., Dev, S., DeVine, L., Gabrielson, K. L., Cole, R. N., Hamilton, J. P. & Lutsenko, S., Jan 2022, In: American Journal of Pathology. 192, 1, p. 146-159 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
HIF-1 Interacts with TRIM28 and DNA-PK to release paused RNA polymerase II and activate target gene transcription in response to hypoxia
Yang, Y., Lu, H., Chen, C., Lyu, Y., Cole, R. N. & Semenza, G. L., Dec 2022, In: Nature communications. 13, 1, 316.Research output: Contribution to journal › Article › peer-review
Open Access -
Identification of Synaptic DGKθ Interactors That Stimulate DGKθ Activity
Barber, C. N., Goldschmidt, H. L., Ma, Q., Devine, L. R., Cole, R. N., Huganir, R. L. & Raben, D. M., Apr 27 2022, In: Frontiers in Synaptic Neuroscience. 14, 855673.Research output: Contribution to journal › Article › peer-review
Open Access -
Interaction of huntingtin with PRMTs and its subsequent arginine methylation affects HTT solubility, phase transition behavior and neuronal toxicity
Ratovitski, T., Jiang, M., O'meally, R. N., Rauniyar, P., Chighladze, E., Faragó, A., Kamath, S. V., Jin, J., Shevelkin, A. V., Cole, R. N. & Ross, C. A., May 15 2022, In: Human molecular genetics. 31, 10, p. 1651-1672 22 p.Research output: Contribution to journal › Article › peer-review
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Multiubiquitination of TRPV4 reduces channel activity independent of surface localization
Aisenberg, W. H., McCray, B. A., Sullivan, J. M., Diehl, E., DeVine, L. R., Alevy, J., Bagnell, A. M., Carr, P., Donohue, J. K., Goretzki, B., Cole, R. N., Hellmich, U. A. & Sumner, C. J., Apr 1 2022, In: Journal of Biological Chemistry. 298, 4, 101826.Research output: Contribution to journal › Article › peer-review
Open Access -
Tbx18 Orchestrates Cytostructural Transdifferentiation of Cardiomyocytes to Pacemaker Cells by Recruiting the Epithelial-Mesenchymal Transition Program
Foster, D. B., Gu, J. M., Kim, E. H., Wolfson, D. W., O'Meally, R., Cole, R. N. & Cho, H. C., Oct 7 2022, In: Journal of proteome research. 21, 10, p. 2277-2292 16 p.Research output: Contribution to journal › Article › peer-review
Open Access -
The Mitochondrial Ca2+ import complex is altered in ADPKD
Yanda, M. K., Tomar, V., Cole, R., Guggino, W. B. & Cebotaru, L., Jan 2022, In: Cell Calcium. 101, 102501.Research output: Contribution to journal › Article › peer-review
Open Access -
2021
Biomonitoring of Ambient Outdoor Air Pollutant Exposure in Humans Using Targeted Serum Albumin Adductomics
Smith, J. W., O'Meally, R. N., Ng, D. K., Chen, J. G., Kensler, T. W., Cole, R. N. & Groopman, J. D., Apr 19 2021, In: Chemical research in toxicology. 34, 4, p. 1183-1196 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Deleting a UBE3A substrate rescues impaired hippocampal physiology and learning in Angelman syndrome mice
Sell, G. L., Xin, W., Cook, E. K., Zbinden, M. A., Schaffer, T. B., O’Meally, R. N., Cole, R. N. & Margolis, S. S., Dec 2021, In: Scientific reports. 11, 1, 19414.Research output: Contribution to journal › Article › peer-review
Open Access -
Diverse mitochondrial abnormalities in a new cellular model of TAFFAZZIN deficiency are remediated by cardiolipin-interacting small molecules
Anzmann, A. F., Sniezek, O. L., Pado, A., Busa, V., Vaz, F. M., Kreimer, S. D., DeVine, L. R., Cole, R. N., Le, A., Kirsch, B. J., Claypool, S. M. & Vernon, H. J., Sep 1 2021, In: Journal of Biological Chemistry. 297, 3, 101005.Research output: Contribution to journal › Article › peer-review
Open Access -
Fluid shear stress enhances differentiation of jejunal human enteroids in Intestine-Chip
Yin, J., Sunuwar, L., Kasendra, M., Yu, H., Tse, C. M., Talbot, C. C., Boronina, T., Cole, R., Karalis, K. & Donowitz, M., Mar 2021, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 320, 3, p. G258-G271Research output: Contribution to journal › Article › peer-review
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Human Breast Milk Enhances Intestinal Mucosal Barrier Function and Innate Immunity in a Healthy Pediatric Human Enteroid Model
Noel, G., In, J. G., Lemme-Dumit, J. M., DeVine, L. R., Cole, R. N., Guerrerio, A. L., Campbell, J. D., Kovbasnjuk, O. & Pasetti, M. F., Jul 13 2021, In: Frontiers in Cell and Developmental Biology. 9, 685171.Research output: Contribution to journal › Article › peer-review
Open Access -
Immortalized striatal precursor neurons from Huntington's disease patient-derived iPS cells as a platform for target identification and screening for experimental therapeutics
Akimov, S. S., Jiang, M., Kedaigle, A. J., Arbez, N., Marque, L. O., Eddings, C. R., Ranum, P. T., Whelan, E., Tang, A., Wang, R., Devine, L. R., Talbot, C. C., Cole, R. N., Ratovitski, T., Davidson, B. L., Fraenkel, E. & Ross, C. A., Dec 15 2021, In: Human molecular genetics. 30, 24, p. 2469-2487 19 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Oxidized CaMKII and O-GlcNAcylation cause increased atrial fibrillation in diabetic mice by distinct mechanisms
Mesubi, O. O., Rokita, A. G., Abrol, N., Wu, Y., Chen, B., Wang, Q., Granger, J. M., Tucker-Bartley, A., Luczak, E. D., Murphy, K. R., Umapathi, P., Banerjee, P. S., Boronina, T. N., Cole, R. N., Maier, L. S., Wehrens, X. H., Pomerantz, J. L., Song, L. S., Ahima, R. S., Hart, G. W., & 2 others, Jan 19 2021, In: Journal of Clinical Investigation. 131, 2, e95747.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Quantitative proteomics reveals that the OGT interactome is remodeled in response to oxidative stress
Martinez, M., Renuse, S., Kreimer, S., O'Meally, R., Natov, P., Madugundu, A. K., Nirujogi, R. S., Tahir, R., Cole, R., Pandey, A. & Zachara, N. E., 2021, In: Molecular and Cellular Proteomics. 20, 100069.Research output: Contribution to journal › Article › peer-review
Open Access -
Systemic deletion of Atp7b modifies the hepatocytes’ response to copper overload in the mouse models of Wilson disease
Muchenditsi, A., Talbot, C. C., Gottlieb, A., Yang, H., Kang, B., Boronina, T., Cole, R., Wang, L., Dev, S., Hamilton, J. P. & Lutsenko, S., Dec 2021, In: Scientific reports. 11, 1, 5659.Research output: Contribution to journal › Article › peer-review
Open Access -
Valsartan nano-filaments alter mitochondrial energetics and promote faster healing in diabetic rat wounds
Nidadavolu, L. S., Stern, D., Lin, R., Wang, Y., Li, Y., Wu, Y., Marin, S., Antonio, M. J., Yenokyan, G., Boronina, T., Cole, R., Foster, D. B., Talbot, C. C., Jedrych, J., Smith, B., Rini, D., Le, A., Cui, H., Walston, J. D. & Abadir, P. M., Nov 1 2021, In: Wound Repair and Regeneration. 29, 6, p. 927-937 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2020
A methodology for discovering novel brain-relevant peptides: Combination of ribosome profiling and peptidomics
Tharakan, R., Kreimer, S., Ubaida-Mohien, C., Lavoie, J., Olexiouk, V., Menschaert, G., Ingolia, N. T., Cole, R. N., Ishizuka, K., Sawa, A. & Nucifora, L. G., Feb 2020, In: Neuroscience Research. 151, p. 31-37 7 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Borrelia burgdorferi-Induced Changes in the Class II Self-Immunopeptidome Displayed on HLA-DR Molecules Expressed by Dendritic Cells
Gutierrez-Hoffmann, M. G., O'Meally, R. N., Cole, R. N., Tiniakou, E., Darrah, E. & Soloski, M. J., Sep 16 2020, In: Frontiers in Medicine. 7, 568.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
C9orf72-Associated smcr8 protein binds in the ubiquitin pathway and with proteins linked with neurological disease
Goodier, J. L., Soares, A. O., Pereira, G. C., Devine, L. R., Sanchez, L., Cole, R. N. & García-Pérez, J. L., Jul 16 2020, In: Acta Neuropathologica Communications. 8, 1, 110.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Definition of Naturally Processed Peptides Reveals Convergent Presentation of Autoantigenic Topoisomerase I Epitopes in Scleroderma
Tiniakou, E., Fava, A., McMahan, Z. H., Guhr, T., O'Meally, R. N., Shah, A. A., Wigley, F. M., Cole, R. N., Boin, F. & Darrah, E., Aug 1 2020, In: Arthritis and Rheumatology. 72, 8, p. 1375-1384 10 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Epithelial WNT2B and Desert Hedgehog Are Necessary for Human Colonoid Regeneration after Bacterial Cytotoxin Injury
In, J. G., Yin, J., Atanga, R., Doucet, M., Cole, R. N., DeVine, L., Donowitz, M., Zachos, N. C., Blutt, S. E., Estes, M. K. & Kovbasnjuk, O., Oct 23 2020, In: iScience. 23, 10, 101618.Research output: Contribution to journal › Article › peer-review
Open Access -
Expanded Chinese hamster organ and cell line proteomics profiling reveals tissue-specific functionalities
Heffner, K., Hizal, D. B., Majewska, N. I., Kumar, S., Dhara, V. G., Zhu, J., Bowen, M., Hatton, D., Yerganian, G., Yerganian, A., O’Meally, R., Cole, R. & Betenbaugh, M., Dec 1 2020, In: Scientific reports. 10, 1, 15841.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Insulin-induced de novo lipid synthesis occurs mainly via mTOR-dependent regulation of proteostasis of SREBP-1c
Dong, Q., Majumdar, G., O’Meally, R. N., Cole, R. N., Elam, M. B. & Raghow, R., Jan 1 2020, In: Molecular and Cellular Biochemistry. 463, 1-2, p. 13-31 19 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Lack of the MHC class II chaperone H2-O causes susceptibility to autoimmune diseases
Welsh, R. A., Song, N., Foss, C. A., Boronina, T., Cole, R. N. & Sadegh-Nasseri, S., Feb 2020, In: PLoS biology. 18, 2, e3000590.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Skin tape proteomics identifies pathways associated with transepidermal water loss and allergen polysensitization in atopic dermatitis
Goleva, E., Calatroni, A., LeBeau, P., Berdyshev, E., Taylor, P., Kreimer, S., Cole, R. N. & Leung, D. Y. M., Dec 2020, In: Journal of Allergy and Clinical Immunology. 146, 6, p. 1367-1378 12 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Stimulus-dependent modifications in astrocyte-derived extracellular vesicle cargo regulate neuronal excitability
Datta Chaudhuri, A., Dasgheyb, R. M., DeVine, L. R., Bi, H., Cole, R. N. & Haughey, N. J., Jan 1 2020, In: Glia. 68, 1, p. 128-144 17 p.Research output: Contribution to journal › Article › peer-review
21 Scopus citations -
2019
Actomyosin contraction during cellularization is regulated in part by Src64 control of Actin 5C protein levels
Carter, T. Y., Gadwala, S., Chougule, A. B., Bui, A. P. N., Sanders, A. C., Chaerkady, R., Cormier, N., Cole, R. N. & Thomas, J. H., Jan 1 2019, In: Genesis. e23297.Research output: Contribution to journal › Review article › peer-review
1 Scopus citations -
Lysyl oxidase-like 2 depletion is protective in age-associated vascular stiffening
Steppan, J., Wang, H., Bergman, Y., Rauer, M. J., Tan, S., Jandu, S., Nandakumar, K., Barreto-Ortiz, S., Cole, R. N., Boronina, T. N., Zhu, W., Halushka, M. K., An, S. S., Berkowitz, D. E. & Santhanam, L., 2019, In: American Journal of Physiology - Heart and Circulatory Physiology. 317, 1, p. H49-H59Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Plasma proteome correlates of lipid and lipoprotein: Biomarkers of metabolic diversity and inflammation in children of rural Nepal
Lee, S. E., Schulze, K., Stewart, C. P., Cole, R. N., Wu, L. S. F., Eroglu, A., Yager, J. D., Groopman, J., Christian, P. & West, K. P., 2019, In: Journal of Lipid Research. 60, 1, p. 149-160 12 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Proteogenomic Annotation of Chinese Hamsters Reveals Extensive Novel Translation Events and Endogenous Retroviral Elements
Li, S., Cha, S. W., Heffner, K., Hizal, D. B., Bowen, M. A., Chaerkady, R., Cole, R. N., Tejwani, V., Kaushik, P., Henry, M., Meleady, P., Sharfstein, S. T., Betenbaugh, M. J., Bafna, V. & Lewis, N. E., Jun 7 2019, In: Journal of proteome research. 18, 6, p. 2433-2445 13 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
The nonlesional skin surface distinguishes atopic dermatitis with food allergy as a unique endotype
Leung, D. Y. M., Calatroni, A., Zaramela, L. S., LeBeau, P. K., Dyjack, N., Brar, K., David, G., Johnson, K., Leung, S., Ramirez-Gama, M., Liang, B., Rios, C., Montgomery, M. T., Richers, B. N., Hall, C. F., Norquest, K. A., Jung, J., Bronova, I., Kreimer, S., Talbot, C. C., & 7 others, 2019, In: Science translational medicine. 11, 480, eaav2685.Research output: Contribution to journal › Article › peer-review
Open Access60 Scopus citations -
The structural unit of melanin in the cell wall of the fungal pathogen Cryptococcus neoformans
Camacho, E., Vij, R., Chrissian, C., Prados-Rosales, R., Gil, D., O'Meally, R. N., Cordero, R. J. B., Cole, R. N., McCaffery, J. M., Stark, R. E. & Casadevall, A., Jul 5 2019, In: Journal of Biological Chemistry. 294, 27, p. 10471-10489 19 p.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
2018
Cholera toxin inhibits SNX27-retromer-mediated delivery of cargo proteins to the plasma membrane
Singh, V., Yang, J., Yin, J., Cole, R., Tse, M., Berman, D. E., Small, S. A., Petsko, G. & Donowitz, M., Aug 1 2018, In: Journal of cell science. 131, 16, jcs.218610.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations