Robert Leone



Research output per year

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Research Output

Metabolism of immune cells in cancer

Leone, R. & Powell, J. D., 2020, (Accepted/In press) In : Nature Reviews Cancer.

Research output: Contribution to journalReview article

  • Targeting glutamine metabolism enhances tumor-specific immunity by modulating suppressive myeloid cells

    Oh, M. H., Sun, I. H., Zhao, L., Leone, R., Sun, I. M., Xu, W., Collins, S. L., Tam, A. J., Blosser, R. L., Patel, C. H., Englert, J. M., Arwood, M. L., Wen, J., Chan-Li, Y., Tenora, L., Majer, P., Rais, R., Slusher, B. S., Horton, M. R. & Powell, J., Jul 1 2020, In : The Journal of clinical investigation. 130, 7, p. 3865-3884 20 p.

    Research output: Contribution to journalArticle

    Open Access
  • Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion

    Leone, R. D., Zhao, L., Englert, J. M., Sun, I. M., Oh, M. H., Sun, I. H., Arwood, M. L., Bettencourt, I. A., Patel, C. H., Wen, J., Tam, A., Blosser, R. L., Prchalova, E., Alt, J., Rais, R., Slusher, B. S. & Powell, J. D., Nov 22 2019, In : Science. 366, 6468, p. 1013-1021 9 p.

    Research output: Contribution to journalArticle

  • Hotspot SF3B1 mutations induce metabolic reprogramming and vulnerability to serine deprivation

    Brian Dalton, W., Helmenstine, E., Walsh, N., Gondek, L. P., Kelkar, D. S., Read, A., Natrajan, R., Christenson, E. S., Roman, B., Das, S., Zhao, L., Leone, R. D., Shinn, D., Groginski, T., Madugundu, A. K., Patil, A., Zabransky, D. J., Medford, A., Lee, J., Cole, A. J. & 12 others, Rosen, M., Thakar, M., Ambinder, A., Donaldson, J., DeZern, A. E., Cravero, K., Chu, D., Madero-Marroquin, R., Pandey, A., Hurley, P. J., Lauring, J. & Park, B. H., Nov 1 2019, In : Journal of Clinical Investigation. 129, 11, p. 4708-4723 16 p.

    Research output: Contribution to journalArticle

  • Targeting metabolism to regulate immune responses in autoimmunity and cancer

    Patel, C. H., Leone, R. D., Horton, M. R. & Powell, J. D., Sep 1 2019, In : Nature Reviews Drug Discovery. 18, 9, p. 669-688 20 p.

    Research output: Contribution to journalReview article