Robert Leone

Instructor

20132019

Research output per year

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Research Output

Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion

Leone, R. D., Zhao, L., Englert, J. M., Sun, I. M., Oh, M. H., Sun, I. H., Arwood, M. L., Bettencourt, I. A., Patel, C. H., Wen, J., Tam, A., Blosser, R. L., Prchalova, E., Alt, J., Rais, R., Slusher, B. S. & Powell, J. D., Nov 22 2019, In : Science. 366, 6468, p. 1013-1021 9 p.

Research output: Contribution to journalArticle

  • Hotspot SF3B1 mutations induce metabolic reprogramming and vulnerability to serine deprivation

    Brian Dalton, W., Helmenstine, E., Walsh, N., Gondek, L. P., Kelkar, D. S., Read, A., Natrajan, R., Christenson, E. S., Roman, B., Das, S., Zhao, L., Leone, R. D., Shinn, D., Groginski, T., Madugundu, A. K., Patil, A., Zabransky, D. J., Medford, A., Lee, J., Cole, A. J. & 12 others, Rosen, M., Thakar, M., Ambinder, A., Donaldson, J., DeZern, A. E., Cravero, K., Chu, D., Madero-Marroquin, R., Pandey, A., Hurley, P. J., Lauring, J. & Park, B. H., Nov 1 2019, In : Journal of Clinical Investigation. 129, 11, p. 4708-4723 16 p.

    Research output: Contribution to journalArticle

  • Targeting metabolism to regulate immune responses in autoimmunity and cancer

    Patel, C. H., Leone, R., Horton, M. & Powell, J., Jan 1 2019, In : Nature Reviews Drug Discovery.

    Research output: Contribution to journalReview article

  • Inhibition of the adenosine A2a receptor modulates expression of T cell coinhibitory receptors and improves effector function for enhanced checkpoint blockade and ACT in murine cancer models

    Leone, R., Sun, I. M., Oh, M. H., Sun, I. H., Wen, J., Englert, J. & Powell, J., Jun 19 2018, (Accepted/In press) In : Cancer Immunology, Immunotherapy. p. 1-14 14 p.

    Research output: Contribution to journalArticle

  • Targeting adenosine for cancer immunotherapy

    Leone, R. & Emens, L. A., Jan 1 2018, In : Journal for immunotherapy of cancer. 6, 1, 57.

    Research output: Contribution to journalReview article

    Open Access