Robert John Adams

Associate Professor

1974 …2019

Research output per year

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Research Output

2008

VMAT2 and dopamine neuron loss in a primate model of Parkinson's disease

Chen, M. K., Kuwabara, H., Zhou, Y., Adams, R. J., Brašić, J. R., McGlothan, J. L., Verina, T., Burton, N. C., Alexander, M., Kumar, A., Wong, D. F. & Guilarte, T. R., Apr 1 2008, In : Journal of Neurochemistry. 105, 1, p. 78-90 13 p.

Research output: Contribution to journalArticle

2007

Expression of a truncated cystic Fibrosis transmembrane conductance regulator with an AAV5-pseudotyped vector in primates

Fischer, A. C., Smith, C. I., Cebotaru, L., Zhang, X., Askin, F. B., Wright, J., Guggino, S. E., Adams, R. J., Flotte, T. & Guggino, W. B., Apr 1 2007, In : Molecular Therapy. 15, 4, p. 756-763 8 p.

Research output: Contribution to journalArticle

Heterologous prime-boost strategy to immunize very young infants against measles: Pre-clinical studies in rhesus macaques

Pasetti, M. F., Resendiz-Albor, A., Ramirez, K., Stout, R., Papania, M., Adams, R. J., Polack, F. P., Ward, B. J., Burt, D., Chabot, S., Ulmer, J., Barry, E. M. & Levine, M. M., Dec 1 2007, In : Clinical pharmacology and therapeutics. 82, 6, p. 672-685 14 p.

Research output: Contribution to journalArticle

Pathogenesis of simian immunodeficiency virus-induced alterations in macaque trigeminal ganglia

Laast, V. A., Pardo, C. A., Tarwater, P. M., Queen, S. E., Reinhart, T. A., Ghosh, M., Adams, R. J., Zink, M. C. & Mankowski, J. L., Jan 1 2007, In : Journal of neuropathology and experimental neurology. 66, 1, p. 26-34 9 p.

Research output: Contribution to journalArticle

2006

Acute manganese administration alters dopamine transporter levels in the non-human primate striatum

Chen, M. K., Lee, J. S., McGlothan, J. L., Furukawa, E., Adams, R. J., Alexander, M., Wong, D. F. & Guilarte, T. R., Mar 1 2006, In : NeuroToxicology. 27, 2, p. 229-236 8 p.

Research output: Contribution to journalArticle

Characterization of an anti-lymphocyte function-associated antigen-1 antibody in a simian immunodeficiency virus-pig-tailed macaque (Macaca nemestrina) model

Fletcher, C. A., Liao, Z., Adams, R. J., Carter, D. L., Jones, O. D., Davis, H. G., Bryant, J. L. & Hildreth, J. E. K., Feb 1 2006, In : Comparative medicine. 56, 1, p. 23-30 8 p.

Research output: Contribution to journalArticle

Enhancing efficacy of HIV Gag DNA vaccine by local delivery of GM-CSF in murine and macaque models

Song, R., Liu, S., Adams, R. J. & Leong, K. W., Jun 1 2006, In : Journal of Interferon and Cytokine Research. 26, 6, p. 380-389 10 p.

Research output: Contribution to journalArticle

Morphine withdrawal dramatically reduces lymphocytes in morphine-dependent macaques

Weed, M. R., Carruth, L. M., Adams, R. J., Ator, N. A. & Hienz, R. D., Sep 1 2006, In : Journal of Neuroimmune Pharmacology. 1, 3, p. 250-259 10 p.

Research output: Contribution to journalArticle

Platelet decline: An early predictive hematologic marker of simian immunodeficiency virus central nervous system disease

Wachtman, L. M., Tarwater, P. M., Queen, S. E., Adams, R. J. & Mankowski, J. L., Feb 1 2006, In : Journal of neurovirology. 12, 1, p. 25-33 9 p.

Research output: Contribution to journalArticle

2005

Modulation of disease, T cell responses, and measles virus clearance in monkeys vaccinated with H-encoding alphavirus replicon particles

Pan, C. H., Valsamakis, A., Colella, T., Nair, N., Adams, R. J., Polack, F. P., Greer, C. E., Perri, S., Polo, J. M. & Griffin, D. E., Aug 16 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 33, p. 11581-11588 8 p.

Research output: Contribution to journalArticle

2003

Elevated peripheral benzodiazepine receptor expression in simian immunodeficiency virus encephalitis

Mankowski, J. L., Queen, S. E., Tarwater, P. J., Adams, R. J. & Guilarte, T. R., Feb 2003, In : Journal of neurovirology. 9, 1, p. 94-100 7 p.

Research output: Contribution to journalReview article

Successful transgene expression with serial doses of aerosolized rAAV2 vectors in rhesus macaques

Fischer, A. C., Beck, S. E., Smith, C. I., Laube, B. L., Askin, F. B., Guggino, S. E., Adams, R. J., Flotte, T. B. & Guggino, W. B., Dec 2003, In : Molecular Therapy. 8, 6, p. 918-926 9 p.

Research output: Contribution to journalArticle

Vaccination of Rhesus Macaques with a Recombinant Measles Virus Expressing Interleukin-12 Alters Humoral and Cellular Immune Responses

Hoffman, S. J., Polack, F. P., Hauer, D. A., Singh, M., Billeter, M. A., Adams, R. J. & Griffin, D. E., Nov 15 2003, In : Journal of Infectious Diseases. 188, 10, p. 1553-1561 9 p.

Research output: Contribution to journalArticle

2002

Deposition and expression of aerosolized rAAV vectors in the lungs of Rhesus macaques

Beck, S. E., Laube, B. L., Barberena, C. I., Fischer, A. C., Adams, R. J., Chesnut, K., Flotte, T. R. & Guggino, W. B., Oct 1 2002, In : Molecular Therapy. 6, 4, p. 546-554 9 p.

Research output: Contribution to journalArticle

2001

In utero AAV-mediated gene transfer to rabbit pulmonary epithelium

Boyle, M. P., Enke, R. A., Adams, R. J., Guggino, W. B. & Zeitlin, P. L., Jan 1 2001, In : Molecular Therapy. 4, 2, p. 115-121 7 p.

Research output: Contribution to journalArticle

Pathogenesis of SIV pneumonia: Selective replication of viral genotypes in the lung

Babas, T., Vieler, E., Hauer, D. A., Adams, R. J., Tarwater, P. M., Fox, K., Clements, J. E. & Zink, M. C., Sep 1 2001, In : Virology. 287, 2, p. 371-381 11 p.

Research output: Contribution to journalArticle

2000

Erratum: Successful DNA immunization against measles: Neutralizing antibody against either the hemagglutinin or fusion glycoprotein protects rhesus macaques without evidence of atypical measles (Nature Medicine (2000) 6 (776-781))

Polack, F. P., Lee, S. H., Permar, S., Manyara, E., Nousari, H. G., Jeng, Y., Mustafa, F., Valsamakis, A., Adams, R. J., Robinson, H. L. & Griffin, D. E., Jan 1 2000, In : Nature medicine. 6, 9, 1 p.

Research output: Contribution to journalComment/debate

Successful DNA immunization against measles: Neutralizing antibody against either the hemagglutinin or fusion glycoprotein protects rhesus macaques without evidence of atypical measles

Polack, F. P., Lee, S. H., Permar, S., Manyara, E., Nousari, H. G., Jeng, Y., Mustafa, F., Valsamakis, A., Adams, R. J., Robinson, H. L. & Griffin, D. E., Jul 1 2000, In : Nature medicine. 6, 7, p. 776-781 6 p.

Research output: Contribution to journalArticle

1999

Alterations in blood-brain barrier glucose transport in SIV-infected macaques

Mankowski, J. L., Queen, S. E., Kirstein, L. M., Spelman, J. P., Laterra, J., Simpson, I. A., Adams, R. J., Clements, J. E. & Zink, M. C., Dec 1999, In : Journal of neurovirology. 5, 6, p. 695-702 8 p.

Research output: Contribution to journalArticle

High viral load in the cerebrospinal fluid and brain correlates with severity of simian immunodeficiency virus encephalitis

Zink, M. C., Suryanarayana, K., Mankowski, J. L., Shen, A., Piatak, M., Spelman, J. P., Carter, D. L., Adams, R. J., Lifson, J. D. & Clements, J. E., Dec 1 1999, In : Journal of virology. 73, 12, p. 10480-10488 9 p.

Research output: Contribution to journalArticle

Measles virus infection in rhesus macaques: Altered immune responses and comparison of the virulence of six different virus strains

Auwaerter, P. G., Rota, P. A., Elkins, W. R., Adams, R. J., DeLozier, T., Shi, Y., Bellini, W. J., Murphy, B. R. & Griffin, D. E., Dec 1 1999, In : Journal of Infectious Diseases. 180, 4, p. 950-958 9 p.

Research output: Contribution to journalArticle

Production of atypical measles in rhesus macaques: Evidence for disease mediated by immune complex formation and eosinophils in the presence of fusion-inhibiting antibody

Polack, F. P., Auwaerter, P. G., Lee, S. H., Nousari, H. C., Valsamakis, A., Leiferman, K. M., Diwan, A., Adams, R. J. & Griffin, D. E., Jun 1 1999, In : Nature medicine. 5, 6, p. 629-634 6 p.

Research output: Contribution to journalArticle

1998

Pathogenesis of simian immunodeficiency virus pneumonia: An immunopathological response to virus

Mankowski, J. L., Carter, D. L., Spelman, J. P., Nealen, M. L., Maughan, K. R., Kirstein, L. M., Didier, P. J., Adams, R. J., Murphey-Corb, M. & Zink, M. C., Oct 1998, In : American Journal of Pathology. 153, 4, p. 1123-1130 8 p.

Research output: Contribution to journalArticle

1997

Pathogenesis of ovine lentiviral encephalitis: Derivation of a neurovirulent strain by in vivo passage

Craig, L. E., Sheffer, D., Meyer, A. L., Hauer, D., Lechner, F., Peterhans, E., Adams, R. J., Clements, J. E., Narayan, O. & Zink, M. C., Dec 1997, In : Journal of neurovirology. 3, 6, p. 417-427 11 p.

Research output: Contribution to journalArticle

Retroperitoneal Hematoma in a Baboon

Piel, M. J. & Adams, R. J., Dec 1 1997, In : Contemporary Topics in Laboratory Animal Science. 36, 2, p. 94-96 3 p.

Research output: Contribution to journalArticle

1996

In vivo model of adeno-associated virus vector persistence and rescue

Afione, S. A., Conrad, C. K., Kearns, W. G., Chunduru, S., Adams, R., Reynolds, T. C., Guggino, W. B., Cutting, G. R., Carter, B. J. & Flotte, T. R., May 3 1996, In : Journal of virology. 70, 5, p. 3235-3241 7 p.

Research output: Contribution to journalArticle

Safety of single-dose administration of an adeno-associated virus (AAV)-CFTR vector in the primate lung

Conrad, C. K., Allen, S. S., Afione, S. A., Reynolds, T. C., Beck, S. E., Fee-Maki, M., Barrazza-Ortiz, X., Adams, R., Askin, F. B., Carter, B. J., Guggino, W. B. & Flotte, T. R., Sep 5 1996, In : Gene Therapy. 3, 8, p. 658-668 11 p.

Research output: Contribution to journalArticle

1994

Early activation of PBMC and appearance of antiviral CD8+ cells influence the prognosis of SIV‐induced disease in rhesus macaques

Joag, S. V., Adams, R. J., Foresman, L., Gaibreath, D., Zink, M. C., Pinson, D. M., McClure, H. & Narayan, O., Jan 1 1994, In : Journal of medical primatology. 23, 2-3, p. 108-116 9 p.

Research output: Contribution to journalArticle

Intracerebral infusion of TNF-α and IL-6 failed to activate latent SIV infection in the brains of macaques inoculated with macrophage-tropic neuroadapted SIV(mac)

Joag, S. V., Adams, R. J., Pinson, D. M., Adany, I. & Narayan, O., Jan 1 1994, In : Journal of Leukocyte Biology. 56, 3, p. 353-357 5 p.

Research output: Contribution to journalArticle

Pathogenesis of SIVmac Infection in Chinese and Indian Rhesus Macaques: Effects of Splenectomy on Virus Burden

Joag, S. V., Stephens, E. B., Adams, R. J., Foresman, L. & Narayan, O., May 1 1994, In : Virology. 200, 2, p. 436-446 11 p., 71207.

Research output: Contribution to journalArticle

1993

Antigenic variation of molecularly cloned sivmac239 during persistent infection in a rhesus macaque

Joag, S. V., Anderson, M. G., Clements, J. E., McEntee, M. F., Sharma, D. P., Adams, R. J. & Narayan, O., Aug 1993, In : Virology. 195, 2, p. 406-412 7 p.

Research output: Contribution to journalArticle

Corynebacterium species-associated keratoconjunctivitis in aged male C57BL/6J mice

McWilliams, T. S., Waggie, K. S., Luzarraga, M. B., French, A. W. & Adams, R. J., Jan 1 1993, In : Laboratory Animal Science. 43, 5, p. 509-512 4 p.

Research output: Contribution to journalArticle

Partial splenic resection using nylon cable tie ligatures in rhesus monkeys

Adams, R. J. & Narayan, O., Jan 1 1993, In : Laboratory animal science. 43, 3, p. 267-269 3 p.

Research output: Contribution to journalArticle

1992

Derivation of neurotropic simian immunodeficiency virus from exclusively lymphocytetropic parental virus: Pathogenesis of infection in macaques

Sharma, D. P., Zink, M. C., Anderson, M., Adams, R., Clements, J. E., Joag, S. V. & Narayan, O., Jan 1 1992, In : Journal of virology. 66, 6, p. 3550-3556 7 p.

Research output: Contribution to journalArticle

Differences in Neutralization of Simian Lentivirus (SIVMAC) in Lymphocyte and Macrophage Cultures

Mcentee, M. F., Anderson, M. G., Daniel, M. D., Adams, R., Farzadegan, H., Desrosiers, R. C. & Narayan, O., Jun 1992, In : AIDS research and human retroviruses. 8, 6, p. 1193-1198 6 p.

Research output: Contribution to journalArticle

Lentivirus induced arthritis in animals

Narayan, O., Zink, M. C., Gorrell, M., McEntee, M., Sharma, D. & Adams, R., Jan 1 1992, In : Journal of Rheumatology. 19, SUPPL. 32, p. 25-32 8 p.

Research output: Contribution to journalArticle

Neutralizing antibodies modulate replication of simian immunodeficiency virus SIV(mac) in primary macaque macrophages

McEntee, M. F., Zink, M. C., Anderson, M. G., Farzadegan, H., Adams, R. J., Kent, K. A., Stott, E. J., Clements, J. E. & Narayan, O., Jan 1 1992, In : Journal of virology. 66, 10, p. 6200-6203 4 p.

Research output: Contribution to journalComment/debate

Ovine lentivirus is macrophagetropic and does not replicate productively in T lymphocytes

Gorrell, M. D., Brandon, M. R., Sheffer, D., Adams, R. J. & Narayan, O., Jan 1 1992, In : Journal of virology. 66, 5, p. 2679-2688 10 p.

Research output: Contribution to journalArticle

Open Access

Pathogenesis of Acute Infection in Rhesus Macaques with a Lymphocyte-Tropic Strain of Simian Immunodeficiency Virus

Sharma, D. P., Anderson, M., Christine Zink, M., Adams, R. J., Donnenberg, A. D., Clements, J. E. & Narayan, O., Oct 1992, In : Journal of Infectious Diseases. 166, 4, p. 738-746 9 p.

Research output: Contribution to journalArticle

Tumour necrosis factor and interleukin 6 production during interaction between activated CD4+ lymphocytes and simian immunodeficiency virus-infected macrophages

McEntee, M. F., Gorrell, M. D., Adams, R. J., Narayan, O. & Pitha, P., Jan 1 1992, In : Journal of General Virology. 73, 5, p. 1107-1113 7 p.

Research output: Contribution to journalArticle

Open Access
1991

Recovery of the simian immunodeficiency virus (SIV) and depression of colony formation in in vitro infected progenitor cell-enriched rhesus bone marrow (BM).

Beltz, L., Narayan, O., Adams, R. J., Noga, S. J. & Donnenberg, A. D., Jun 1991, In : Journal of medical primatology. 20, 4, p. 144-151 8 p.

Research output: Contribution to journalArticle

Rhesus monkey macrophages infected with simian immunodeficiency virus cause rapid lysis of CD4-bearing lymphocytes

McEntee, M. F., Sharma, D. P., Zink, M. C., Adams, R. J., Flexner, C., Clements, J. E. & Narayan, O., Jan 1 1991, In : Journal of General Virology. 72, 2, p. 317-324 8 p.

Research output: Contribution to journalArticle

Open Access
1990

Methanol-powered cars

Adams, R. J., Jan 1 1990, In : Science. 247, 4941, 1 p.

Research output: Contribution to journalLetter

1986

Absence of left ventricular dysfunction during acute chagasic myocarditis in the rhesus monkey

Lima, J. A. C., Szarfman, A., Lima, S. D., Adams, R. J., Russell, R. J., Cheever, A., Trischmann, T. & Weiss, J. L., Jan 1 1986, In : Circulation. 73, 1, p. 172-179 8 p.

Research output: Contribution to journalArticle

Open Access

Ventricular septal defect in a rhesus monkey.

Swindle, M. M., Kan, J. S., Adams, R. J., Starr, F. L., Samphilipo, M. A. & Porter, W. P., Dec 1 1986, In : Laboratory animal science Chicago. 36, 6, p. 693-695 3 p.

Research output: Contribution to journalArticle

1985

Surgical correction of genital prolapse in three rhesus monkeys

Adams, R. J., Rock, J. A., Swindle, M. M., Garnett, N. L. & Porter, W. P., Dec 1 1985, In : Laboratory animal science. 35, 4, p. 405-408 4 p.

Research output: Contribution to journalArticle

1983

Posterior corneal rings in monkeys

Hirst, L. W., Dunkelberger, G., Adams, R. J. & Kues, H. A., Jan 1 1983, In : Investigative Ophthalmology and Visual Science. 24, 5, p. 586-588 3 p.

Research output: Contribution to journalArticle

Somatic tissue responses of male rhesus monkeys treated with a contraceptive steroid formulation

Ewing, L. L., Huber, A. C., Strandberg, J. D., Adams, R. J., Cochran, R. C. & Desjardins, C., Apr 1983, In : Contraception. 27, 4, p. 363-381 19 p.

Research output: Contribution to journalArticle