Robert John Adams

Associate Professor

1974 …2020

Research output per year

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Research Output

Article

Lymphocyte-Dominant Encephalitis and Meningitis in Simian Immunodeficiency Virus–Infected Macaques Receiving Antiretroviral Therapy

Mangus, L., Beck, S., Queen, S. E., Brill, S. A., Shirk, E. N., Pate, K., Muth, D. C., Adams, R. J., Gama, L., Clements, J. E. & Mankowski, J. L., Jan 1 2018, In : American Journal of Pathology. 188, 1, p. 125-134 10 p.

Research output: Contribution to journalArticle

Macrophage-mediated dorsal root ganglion damage precedes altered nerve conduction in SIV-infected macaques

Laast, V. A., Shim, B., Johanek, L. M., Dorsey, J. L., Hauer, P. E., Tarwater, P. M., Adams, R. J., Pardo, C. A., McArthur, J. C., Ringkamp, M. & Mankowski, J. L., Nov 1 2011, In : American Journal of Pathology. 179, 5, p. 2337-2345 9 p.

Research output: Contribution to journalArticle

Measles virus infection in rhesus macaques: Altered immune responses and comparison of the virulence of six different virus strains

Auwaerter, P. G., Rota, P. A., Elkins, W. R., Adams, R. J., DeLozier, T., Shi, Y., Bellini, W. J., Murphy, B. R. & Griffin, D. E., Dec 1 1999, In : Journal of Infectious Diseases. 180, 4, p. 950-958 9 p.

Research output: Contribution to journalArticle

Modulation of disease, T cell responses, and measles virus clearance in monkeys vaccinated with H-encoding alphavirus replicon particles

Pan, C. H., Valsamakis, A., Colella, T., Nair, N., Adams, R. J., Polack, F. P., Greer, C. E., Perri, S., Polo, J. M. & Griffin, D. E., Aug 16 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 33, p. 11581-11588 8 p.

Research output: Contribution to journalArticle

Morphine withdrawal dramatically reduces lymphocytes in morphine-dependent macaques

Weed, M. R., Carruth, L. M., Adams, R. J., Ator, N. A. & Hienz, R. D., Sep 1 2006, In : Journal of Neuroimmune Pharmacology. 1, 3, p. 250-259 10 p.

Research output: Contribution to journalArticle

Natural host genetic resistance to lentiviral CNS sisease: A neuroprotective MHC class I allele in SIV-infected macaques

Mankowski, J. L., Queen, S. E., Fernandez, C. S., Tarwater, P. M., Karper, J. M., Adams, R. J. & Kent, S. J., Nov 3 2008, In : PloS one. 3, 11, e3603.

Research output: Contribution to journalArticle

Neurocognitive dysfunction and pharmacological intervention using guanfacine in a rhesus macaque model of self-injurious behavior

Freeman, Z. T., Rice, K. A., Soto, P. L., Pate, K. A. M., Weed, M. R., Ator, N. A., DeLeon, I. G., Wong, D. F., Zhou, Y., Mankowski, J. L., Zink, M. C., Adams, R. J. & Hutchinson, E. K., May 26 2015, In : Translational Psychiatry. 5, 5, e567.

Research output: Contribution to journalArticle

Neuroinflammation and virus replication in the spinal cord of simian immunodeficiency virus-infected macaques

Mangus, L. M., Dorsey, J. L., Laast, V. A., Hauer, P., Queen, S. E., Adams, R. J., McArthur, J. C. & Mankowski, J. L., Jan 3 2015, In : Journal of neuropathology and experimental neurology. 74, 1, p. 38-47 10 p.

Research output: Contribution to journalArticle

Neuroprotective maraviroc monotherapy in simian immunodeficiency virus-infected macaques: Reduced replicating and latent SIV in the brain

Kelly, K. M., Beck, S. E., Pate, K. A. M., Queen, S. E., Dorsey, J. L., Adams, R. J., Avery, L. B., Hubbard, W., Tarwater, P. M. & Mankowski, J. L., Nov 28 2013, In : AIDS. 27, 18, p. F21-F28

Research output: Contribution to journalArticle

Osteopontin enhances HIV replication and is increased in the brain and cerebrospinal fluid of HIV-infected individuals

Brown, A., Islam, T., Adams, R., Nerle, S., Kamara, M., Eger, C., Marder, K., Cohen, B., Schifitto, G., McArthur, J. C., Sacktor, N. & Pardo, C. A., Aug 1 2011, In : Journal of neurovirology. 17, 4, p. 382-392 11 p.

Research output: Contribution to journalArticle

Ovine lentivirus is macrophagetropic and does not replicate productively in T lymphocytes

Gorrell, M. D., Brandon, M. R., Sheffer, D., Adams, R. J. & Narayan, O., Jan 1 1992, In : Journal of virology. 66, 5, p. 2679-2688 10 p.

Research output: Contribution to journalArticle

Open Access

Partial splenic resection using nylon cable tie ligatures in rhesus monkeys

Adams, R. J. & Narayan, O., Jan 1 1993, In : Laboratory animal science. 43, 3, p. 267-269 3 p.

Research output: Contribution to journalArticle

Pathogenesis of Acute Infection in Rhesus Macaques with a Lymphocyte-Tropic Strain of Simian Immunodeficiency Virus

Sharma, D. P., Anderson, M., Christine Zink, M., Adams, R. J., Donnenberg, A. D., Clements, J. E. & Narayan, O., Oct 1992, In : Journal of Infectious Diseases. 166, 4, p. 738-746 9 p.

Research output: Contribution to journalArticle

Pathogenesis of ovine lentiviral encephalitis: Derivation of a neurovirulent strain by in vivo passage

Craig, L. E., Sheffer, D., Meyer, A. L., Hauer, D., Lechner, F., Peterhans, E., Adams, R. J., Clements, J. E., Narayan, O. & Zink, M. C., Dec 1997, In : Journal of neurovirology. 3, 6, p. 417-427 11 p.

Research output: Contribution to journalArticle

Pathogenesis of simian immunodeficiency virus-induced alterations in macaque trigeminal ganglia

Laast, V. A., Pardo, C. A., Tarwater, P. M., Queen, S. E., Reinhart, T. A., Ghosh, M., Adams, R. J., Zink, M. C. & Mankowski, J. L., Jan 1 2007, In : Journal of neuropathology and experimental neurology. 66, 1, p. 26-34 9 p.

Research output: Contribution to journalArticle

Pathogenesis of simian immunodeficiency virus pneumonia: An immunopathological response to virus

Mankowski, J. L., Carter, D. L., Spelman, J. P., Nealen, M. L., Maughan, K. R., Kirstein, L. M., Didier, P. J., Adams, R. J., Murphey-Corb, M. & Zink, M. C., Oct 1998, In : American Journal of Pathology. 153, 4, p. 1123-1130 8 p.

Research output: Contribution to journalArticle

Pathogenesis of SIVmac Infection in Chinese and Indian Rhesus Macaques: Effects of Splenectomy on Virus Burden

Joag, S. V., Stephens, E. B., Adams, R. J., Foresman, L. & Narayan, O., May 1 1994, In : Virology. 200, 2, p. 436-446 11 p., 71207.

Research output: Contribution to journalArticle

Pathogenesis of SIV pneumonia: Selective replication of viral genotypes in the lung

Babas, T., Vieler, E., Hauer, D. A., Adams, R. J., Tarwater, P. M., Fox, K., Clements, J. E. & Zink, M. C., Sep 1 2001, In : Virology. 287, 2, p. 371-381 11 p.

Research output: Contribution to journalArticle

Persistent peripheral nervous system damage in simian immunodeficiency virus-infected macaques receiving antiretroviral therapy

Dorsey, J. L., Mangus, L. M., Hauer, P., Ebenezer, G. J., Queen, S. E., Laast, V. A., Adams, R. J. & Mankowski, J. L., Jan 1 2015, In : Journal of neuropathology and experimental neurology. 74, 11, p. 1053-1060 8 p.

Research output: Contribution to journalArticle

Open Access

Pharmacokinetics and immunogenicity of a recombinant human butyrylcholinesterase bioscavenger in macaques following intravenous and pulmonary delivery

Rosenberg, Y. J., Adams, R. J., Hernandez-Abanto, S., Jiang, X., Sun, W., Mao, L. & Lee, K. D., Dec 5 2015, In : Chemico-Biological Interactions. 242, p. 219-226 8 p.

Research output: Contribution to journalArticle

Platelet activation and platelet-monocyte aggregate formation contribute to decreased platelet count during acute simian immunodeficiency virus infection in pig-tailed macaques

Metcalf Pate, K. A., Lyons, C. E., Dorsey, J. L., Shirk, E. N., Queen, S. E., Adams, R. J., Gama, L., Morrell, C. N. & Mankowski, J. L., Sep 15 2013, In : Journal of Infectious Diseases. 208, 6, p. 874-883 10 p.

Research output: Contribution to journalArticle

Platelet decline: An early predictive hematologic marker of simian immunodeficiency virus central nervous system disease

Wachtman, L. M., Tarwater, P. M., Queen, S. E., Adams, R. J. & Mankowski, J. L., Feb 1 2006, In : Journal of neurovirology. 12, 1, p. 25-33 9 p.

Research output: Contribution to journalArticle

Poor immune responses of newborn rhesus macaques to measles virus DNA vaccines expressing the hemagglutinin and fusion glycoproteins

Polack, F. P., Lydy, S. L., Lee, S. H., Rota, P. A., Bellini, W. J., Adams, R. J., Robinson, H. L. & Griffin, D. E., Feb 1 2013, In : Clinical and Vaccine Immunology. 20, 2, p. 205-210 6 p.

Research output: Contribution to journalArticle

Posterior corneal rings in monkeys

Hirst, L. W., Dunkelberger, G., Adams, R. J. & Kues, H. A., Jan 1 1983, In : Investigative Ophthalmology and Visual Science. 24, 5, p. 586-588 3 p.

Research output: Contribution to journalArticle

Potential role of cervicovaginal extracellular particles in diagnosis of endometriosis

Muth, D. C., McAlexander, M. A., Ostrenga, L. J., Pate, N. M., Izzi, J. M., Adams, R. J., Pate, K. A. M., Beck, S. E., Karim, B. & Witwer, K. W., Aug 8 2015, In : BMC veterinary research. 11, 1, 187.

Research output: Contribution to journalArticle

Production of atypical measles in rhesus macaques: Evidence for disease mediated by immune complex formation and eosinophils in the presence of fusion-inhibiting antibody

Polack, F. P., Auwaerter, P. G., Lee, S. H., Nousari, H. C., Valsamakis, A., Leiferman, K. M., Diwan, A., Adams, R. J. & Griffin, D. E., Jun 1 1999, In : Nature medicine. 5, 6, p. 629-634 6 p.

Research output: Contribution to journalArticle

Prolonged persistence of measles virus RNA is characteristic of primary infection dynamics

Lin, W. H. W., Kouyos, R. D., Adams, R. J., Grenfell, B. T. & Griffin, D. E., Sep 11 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 37, p. 14989-14994 6 p.

Research output: Contribution to journalArticle

Pulmonary delivery of an aerosolized recombinant human butyrylcholinesterase pretreatment protects against aerosolized paraoxon in macaques

Rosenberg, Y. J., Laube, B., Mao, L., Jiang, X., Hernandez-Abanto, S., Lee, K. D. & Adams, R., Mar 25 2013, In : Chemico-Biological Interactions. 203, 1, p. 167-171 5 p.

Research output: Contribution to journalArticle

Recovery of the simian immunodeficiency virus (SIV) and depression of colony formation in in vitro infected progenitor cell-enriched rhesus bone marrow (BM).

Beltz, L., Narayan, O., Adams, R. J., Noga, S. J. & Donnenberg, A. D., Jun 1991, In : Journal of medical primatology. 20, 4, p. 144-151 8 p.

Research output: Contribution to journalArticle

Replication-competent simian immunodeficiency virus (SIV) gag escape mutations archived in latent reservoirs during antiretroviral treatment of SIV-infected macaques

Queen, S. E., Mears, B. M., Kelly, K. M., Dorsey, J. L., Liao, Z., Dinoso, J. B., Gama, L., Adams, R. J., Zink, M. C., Clements, J. E., Kent, S. J. & Mankowski, J. L., Sep 1 2011, In : Journal of virology. 85, 17, p. 9167-9175 9 p.

Research output: Contribution to journalArticle

Retroperitoneal Hematoma in a Baboon

Piel, M. J. & Adams, R. J., Dec 1 1997, In : Contemporary Topics in Laboratory Animal Science. 36, 2, p. 94-96 3 p.

Research output: Contribution to journalArticle

Rhesus monkey macrophages infected with simian immunodeficiency virus cause rapid lysis of CD4-bearing lymphocytes

McEntee, M. F., Sharma, D. P., Zink, M. C., Adams, R. J., Flexner, C., Clements, J. E. & Narayan, O., Jan 1 1991, In : Journal of General Virology. 72, 2, p. 317-324 8 p.

Research output: Contribution to journalArticle

Open Access

Safety of single-dose administration of an adeno-associated virus (AAV)-CFTR vector in the primate lung

Conrad, C. K., Allen, S. S., Afione, S. A., Reynolds, T. C., Beck, S. E., Fee-Maki, M., Barrazza-Ortiz, X., Adams, R., Askin, F. B., Carter, B. J., Guggino, W. B. & Flotte, T. R., Sep 5 1996, In : Gene Therapy. 3, 8, p. 658-668 11 p.

Research output: Contribution to journalArticle

Serum albumin and body weight as biomarkers for the antemortem identification of bone and gastrointestinal disease in the common marmoset

Baxter, V. K., Shaw, G. C., Sotuyo, N. P., Carlson, C. S., Olson, E. J., Christine Zink, M., Mankowski, J. L., Adams, R. J., Hutchinson, E. K. & Metcalf Pate, K. A., Dec 6 2013, In : PloS one. 8, 12, e82747.

Research output: Contribution to journalArticle

SIV-Induced Immune Activation and Metabolic Alterations in the Dorsal Root Ganglia During Acute Infection

Mangus, L., Weinberg, R. L., Knight, A. C., Queen, S. E., Adams, R. J. & Mankowski, J. L., Jan 1 2019, In : Journal of Neuropathology and Experimental Neurology. 78, 1, p. 78-87 10 p.

Research output: Contribution to journalArticle

SIV-induced impairment of neurovascular repair: A potential role for VEGF

Ebenezer, G. J., McArthur, J. C., Polydefkis, M., Dorsey, J. L., O'Donnell, R., Hauer, P., Adams, R. J. & Mankowski, J. L., Jun 1 2012, In : Journal of neurovirology. 18, 3, p. 222-230 9 p.

Research output: Contribution to journalArticle

Somatic tissue responses of male rhesus monkeys treated with a contraceptive steroid formulation

Ewing, L. L., Huber, A. C., Strandberg, J. D., Adams, R. J., Cochran, R. C. & Desjardins, C., Apr 1983, In : Contraception. 27, 4, p. 363-381 19 p.

Research output: Contribution to journalArticle

Successful DNA immunization against measles: Neutralizing antibody against either the hemagglutinin or fusion glycoprotein protects rhesus macaques without evidence of atypical measles

Polack, F. P., Lee, S. H., Permar, S., Manyara, E., Nousari, H. G., Jeng, Y., Mustafa, F., Valsamakis, A., Adams, R. J., Robinson, H. L. & Griffin, D. E., Jul 1 2000, In : Nature medicine. 6, 7, p. 776-781 6 p.

Research output: Contribution to journalArticle

Successful respiratory immunization with dry powder live-attenuated measles virus vaccine in rhesus macaques

Lin, W. H., Griffin, D. E., Rota, P. A., Papania, M., Cape, S. P., Bennett, D., Quinn, B., Sievers, R. E., Shermer, C., Powell, K., Adams, R. J., Godin, S. & Winston, S., Feb 15 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 7, p. 2987-2992 6 p.

Research output: Contribution to journalArticle

Successful transgene expression with serial doses of aerosolized rAAV2 vectors in rhesus macaques

Fischer, A. C., Beck, S. E., Smith, C. I., Laube, B. L., Askin, F. B., Guggino, S. E., Adams, R. J., Flotte, T. B. & Guggino, W. B., Dec 2003, In : Molecular Therapy. 8, 6, p. 918-926 9 p.

Research output: Contribution to journalArticle

Surgical correction of genital prolapse in three rhesus monkeys

Adams, R. J., Rock, J. A., Swindle, M. M., Garnett, N. L. & Porter, W. P., Dec 1 1985, In : Laboratory animal science. 35, 4, p. 405-408 4 p.

Research output: Contribution to journalArticle

Testis function in rhesus monkeys treated with a contraceptive steroid formulation

Ewing, L. L., Cochran, R. C., Adams, R. J., Darney, K. J., Berry, S. J., Bordy, M. J. & Desjardins, C., Apr 1983, In : Contraception. 27, 4, p. 347-362 16 p.

Research output: Contribution to journalArticle

TGFβ-mediated downregulation of thrombopoietin is associated with platelet decline in asymptomatic SIV infection

Pate, K. A. M., Lyons, C. E., Dorsey, J. L., Queen, S. E., Adams, R. J., Morrell, C. N. & Mankowski, J. L., Apr 15 2014, In : Journal of acquired immune deficiency syndromes. 65, 5, p. 510-516 7 p.

Research output: Contribution to journalArticle

The cerebrospinal fluid in visna, a slow viral disease of sheep

Griffin, D. E., Narayan, O., Bukowski, J. F., Adams, R. J. & Cohen, S. R., Sep 1978, In : Annals of neurology. 4, 3, p. 212-218 7 p.

Research output: Contribution to journalArticle