Robert John Adams

Associate Professor

1974 …2019

Research output per year

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Research Output

Absence of left ventricular dysfunction during acute chagasic myocarditis in the rhesus monkey

Lima, J. A. C., Szarfman, A., Lima, S. D., Adams, R. J., Russell, R. J., Cheever, A., Trischmann, T. & Weiss, J. L., Jan 1 1986, In : Circulation. 73, 1, p. 172-179 8 p.

Research output: Contribution to journalArticle

Open Access

A chimeric alphavirus replicon particle vaccine expressing the hemagglutinin and fusion proteins protects juvenile and infant rhesus macaques from measles

Pan, C. H., Greer, C. E., Hauer, D., Legg, H. S., Lee, E. Y., Bergen, M. J., Lau, B., Adams, R. J., Polo, J. M. & Griffin, D. E., Apr 1 2010, In : Journal of virology. 84, 8, p. 3798-3807 10 p.

Research output: Contribution to journalArticle

Acute manganese administration alters dopamine transporter levels in the non-human primate striatum

Chen, M. K., Lee, J. S., McGlothan, J. L., Furukawa, E., Adams, R. J., Alexander, M., Wong, D. F. & Guilarte, T. R., Mar 1 2006, In : NeuroToxicology. 27, 2, p. 229-236 8 p.

Research output: Contribution to journalArticle

Alterations in blood-brain barrier glucose transport in SIV-infected macaques

Mankowski, J. L., Queen, S. E., Kirstein, L. M., Spelman, J. P., Laterra, J., Simpson, I. A., Adams, R. J., Clements, J. E. & Zink, M. C., Dec 1999, In : Journal of neurovirology. 5, 6, p. 695-702 8 p.

Research output: Contribution to journalArticle

A murine viral outgrowth assay to detect residual HIV type 1 in patients with undetectable viral loads

Metcalf Pate, K. A., Pohlmeyer, C. W., Walker-Sperling, V. E., Foote, J. B., Najarro, K. M., Cryer, C. G., Salgado, M., Gama, L., Engle, E. L., Shirk, E. N., Queen, S. E., Chioma, S., Vermillion, M. S., Bullock, B., Li, M., Lyons, C. E., Adams, R. J., Zink, M. C., Clements, J. E., Mankowski, J. L. & 1 others, Blankson, J. N., Nov 1 2015, In : Journal of Infectious Diseases. 212, 9, p. 1387-1396 10 p.

Research output: Contribution to journalArticle

Animal model of human disease. Motor neuron disease: Spinal muscular atrophy and amyotrophic lateral sclerosis

Cork, L. C., Griffin, J. W., Adams, R. J. & Price, D. L., Dec 1 1980, In : American Journal of Pathology. 100, 2, p. 599-602 4 p.

Research output: Contribution to journalArticle

An oral disease resembling noma in six rhesus monkeys (Macaca mulatta)

Adams, R. J. & Bishop, J. L., Jan 1 1980, In : Laboratory Animal Science. 30, 1, p. 85-91 7 p.

Research output: Contribution to journalArticle

An SIV/macaque model targeted to study HIV-associated neurocognitive disorders

Beck, S., Queen, S. E., Pate, K., Mangus, L., Abreu, C. M., Gama, L., Witwer, K. W., Adams, R. J., Zink, M. C., Clements, J. E. & Mankowski, J. L., Oct 3 2017, (Accepted/In press) In : Journal of NeuroVirology. p. 1-9 9 p.

Research output: Contribution to journalArticle

Antigenic variation of molecularly cloned sivmac239 during persistent infection in a rhesus macaque

Joag, S. V., Anderson, M. G., Clements, J. E., McEntee, M. F., Sharma, D. P., Adams, R. J. & Narayan, O., Aug 1993, In : Virology. 195, 2, p. 406-412 7 p.

Research output: Contribution to journalArticle

A replicating adenovirus capsid display recombinant elicits antibodies against Plasmodium falciparum sporozoites in Aotus nancymaae monkeys

Karen, K. A., Deal, C., Adams, R. J., Nielsen, C., Ward, C., Espinosa, D. A., Xie, J., Zavala, F. & Ketner, G., Jan 1 2015, In : Infection and immunity. 83, 1, p. 268-275 8 p.

Research output: Contribution to journalArticle

CCR5 inhibition prevents cardiac dysfunction in the SIV/macaque model of HIV.

Kelly, K. M., Tocchetti, C. G., Lyashkov, A., Tarwater, P. M., Bedja, D., Graham, D. R., Beck, S. E., Metcalf Pate, K. A., Queen, S. E., Adams, R. J., Paolocci, N. & Mankowski, J. L., 2014, In : Journal of the American Heart Association. 3, 2, p. e000874

Research output: Contribution to journalArticle

Characterization of an anti-lymphocyte function-associated antigen-1 antibody in a simian immunodeficiency virus-pig-tailed macaque (Macaca nemestrina) model

Fletcher, C. A., Liao, Z., Adams, R. J., Carter, D. L., Jones, O. D., Davis, H. G., Bryant, J. L. & Hildreth, J. E. K., Feb 1 2006, In : Comparative medicine. 56, 1, p. 23-30 8 p.

Research output: Contribution to journalArticle

Chronic active hepatitis in dogs associated with leptospires.

Bishop, L., Strandberg, J. D., Adams, R. J., Brownstein, D. G. & Patterson, R., Jun 1 1979, In : American journal of veterinary research. 40, 6, p. 839-844 6 p.

Research output: Contribution to journalArticle

Clonal characteristics of experimentally induced " atherosclerotic" lesions in the hybrid hare

Pearson, T. A., Dillman, J., Williams, K. J., Wolff, J. A., Adams, R., Solez, K., Heptinstall, R. H., Malmros, H. & Sternby, N., Jan 1 1979, In : Science. 206, 4425, p. 1423-1425 3 p.

Research output: Contribution to journalArticle

Corrigendum to "vaccination with hpv16 l2e6e7 fusion protein in gpi-0100 adjuvant elicits protective humoral and cell-mediated immunity" [vaccine 27 (2009) 1040-1049]

Karanam, B., Gambhira, R., Peng, S., Jagu, S., Kim, D. J., Ketner, G. W., Stern, P. L., Adams, R. J. & Roden, R. B. S., Jan 3 2014, In : Vaccine. 32, 2, 1 p.

Research output: Contribution to journalComment/debate

Corynebacterium species-associated keratoconjunctivitis in aged male C57BL/6J mice

McWilliams, T. S., Waggie, K. S., Luzarraga, M. B., French, A. W. & Adams, R. J., Jan 1 1993, In : Laboratory Animal Science. 43, 5, p. 509-512 4 p.

Research output: Contribution to journalArticle

Deposition and expression of aerosolized rAAV vectors in the lungs of Rhesus macaques

Beck, S. E., Laube, B. L., Barberena, C. I., Fischer, A. C., Adams, R. J., Chesnut, K., Flotte, T. R. & Guggino, W. B., Oct 1 2002, In : Molecular Therapy. 6, 4, p. 546-554 9 p.

Research output: Contribution to journalArticle

Derivation of neurotropic simian immunodeficiency virus from exclusively lymphocytetropic parental virus: Pathogenesis of infection in macaques

Sharma, D. P., Zink, M. C., Anderson, M., Adams, R., Clements, J. E., Joag, S. V. & Narayan, O., Jan 1 1992, In : Journal of virology. 66, 6, p. 3550-3556 7 p.

Research output: Contribution to journalArticle

Diastolic dysfunction is associated with myocardial viral load in simian immunodeficiency virus-infected macaques

Kelly, K. M., Tarwater, P. M., Karper, J. M., Bedja, D., Queen, S. E., Tunin, R. S., Adams, R. J., Kass, D. A. & Mankowski, J. L., Apr 24 2012, In : AIDS. 26, 7, p. 815-823 9 p.

Research output: Contribution to journalArticle

Differences in Neutralization of Simian Lentivirus (SIVMAC) in Lymphocyte and Macrophage Cultures

Mcentee, M. F., Anderson, M. G., Daniel, M. D., Adams, R., Farzadegan, H., Desrosiers, R. C. & Narayan, O., Jun 1992, In : AIDS research and human retroviruses. 8, 6, p. 1193-1198 6 p.

Research output: Contribution to journalArticle

Discovery of 6-Diazo-5-oxo- l -norleucine (DON) Prodrugs with Enhanced CSF Delivery in Monkeys: A Potential Treatment for Glioblastoma

Rais, R., Jančařík, A., Tenora, L., Nedelcovych, M., Alt, J., Englert, J., Rojas, C., Le, A., Elgogary, A., Tan, J., Monincová, L., Pate, K., Adams, R., Ferraris, D., Powell, J., Majer, P. & Slusher, B. S., Sep 22 2016, In : Journal of medicinal chemistry. 59, 18, p. 8621-8633 13 p.

Research output: Contribution to journalArticle

Dose-dependent protection against or exacerbation of disease by a polylactide glycolide microparticle-adsorbed, alphavirus-based measles virus DNA vaccine in rhesus macaques

Pan, C. H., Nair, N., Adams, R. J., Zink, M. C., Lee, E. Y., Polack, F. P., Singh, M., O'Hagan, D. T. & Griffin, D. E., Apr 1 2008, In : Clinical and Vaccine Immunology. 15, 4, p. 697-706 10 p.

Research output: Contribution to journalArticle

Early activation of PBMC and appearance of antiviral CD8+ cells influence the prognosis of SIV‐induced disease in rhesus macaques

Joag, S. V., Adams, R. J., Foresman, L., Gaibreath, D., Zink, M. C., Pinson, D. M., McClure, H. & Narayan, O., Jan 1 1994, In : Journal of medical primatology. 23, 2-3, p. 108-116 9 p.

Research output: Contribution to journalArticle

Early immune responses in visna, a slow viral disease of sheep

Griffin, D. E., Narayan, O. & Adams, R. J., Sep 1978, In : Journal of Infectious Diseases. 138, 3, p. 340-350 11 p.

Research output: Contribution to journalArticle

Elevated peripheral benzodiazepine receptor expression in simian immunodeficiency virus encephalitis

Mankowski, J. L., Queen, S. E., Tarwater, P. J., Adams, R. J. & Guilarte, T. R., Feb 2003, In : Journal of neurovirology. 9, 1, p. 94-100 7 p.

Research output: Contribution to journalReview article

Enhancing efficacy of HIV Gag DNA vaccine by local delivery of GM-CSF in murine and macaque models

Song, R., Liu, S., Adams, R. J. & Leong, K. W., Jun 1 2006, In : Journal of Interferon and Cytokine Research. 26, 6, p. 380-389 10 p.

Research output: Contribution to journalArticle

Erratum: Successful DNA immunization against measles: Neutralizing antibody against either the hemagglutinin or fusion glycoprotein protects rhesus macaques without evidence of atypical measles (Nature Medicine (2000) 6 (776-781))

Polack, F. P., Lee, S. H., Permar, S., Manyara, E., Nousari, H. G., Jeng, Y., Mustafa, F., Valsamakis, A., Adams, R. J., Robinson, H. L. & Griffin, D. E., Jan 1 2000, In : Nature medicine. 6, 9, 1 p.

Research output: Contribution to journalComment/debate

Evolution of T Cell Responses during Measles Virus Infection and RNA Clearance

Nelson, A. N., Putnam, N., Hauer, D., Baxter, V. K., Adams, R. J. & Griffin, D. E., Dec 1 2017, In : Scientific reports. 7, 1, 11474.

Research output: Contribution to journalArticle

Expression of a truncated cystic Fibrosis transmembrane conductance regulator with an AAV5-pseudotyped vector in primates

Fischer, A. C., Smith, C. I., Cebotaru, L., Zhang, X., Askin, F. B., Wright, J., Guggino, S. E., Adams, R. J., Flotte, T. & Guggino, W. B., Apr 1 2007, In : Molecular Therapy. 15, 4, p. 756-763 8 p.

Research output: Contribution to journalArticle

Genetically determined deficiency of the third component of complement in the dog

Winkelstein, J. A., Cork, L. C., Griffin, D. E., Griffin, J. W., Adams, R. J. & Price, D. L., Jan 1 1981, In : Science. 212, 4499, p. 1169-1170 2 p.

Research output: Contribution to journalArticle

Genetic characterization of a captive colony of pigtailed Macaques (Macaca nemestrina)

Zhang, X., Kanthaswamy, S., Trask, J. S., Ng, J., Oldt, R. F., Mankowski, J. L., Adams, R. J. & Smith, D. G., Jul 1 2017, In : Journal of the American Association for Laboratory Animal Science. 56, 4, p. 390-395 6 p.

Research output: Contribution to journalArticle

Hereditary canine spinal muscular atrophy

Cork, L. C., Griffin, J. W., Munnell, J. F., Lorenz, M. D., Adams, R. J. & Price, D. L., Jan 1 1979, In : Journal of neuropathology and experimental neurology. 38, 3, p. 209-221 13 p.

Research output: Contribution to journalArticle

Hereditary canine spinal muscular atrophy: a canine model of human motor neuron disease.

Cork, L. C., Adams, R. J., Griffin, J. W. & Price, D. L., Jan 1 1982, In : Progress in clinical and biological research. 94, p. 449-458 10 p.

Research output: Contribution to journalArticle

Hereditary spinal muscular atrophy in Brittany Spaniels: Clinical manifestations

Lorenz, M. D., Cork, L. C., Griffin, J. W., Adams, R. J. & Price, D. L., Dec 1 1979, In : Journal of the American Veterinary Medical Association. 175, 8, p. 833-839 7 p.

Research output: Contribution to journalArticle

Heterologous prime-boost strategy to immunize very young infants against measles: Pre-clinical studies in rhesus macaques

Pasetti, M. F., Resendiz-Albor, A., Ramirez, K., Stout, R., Papania, M., Adams, R. J., Polack, F. P., Ward, B. J., Burt, D., Chabot, S., Ulmer, J., Barry, E. M. & Levine, M. M., Dec 1 2007, In : Clinical pharmacology and therapeutics. 82, 6, p. 672-685 14 p.

Research output: Contribution to journalArticle

High viral load in the cerebrospinal fluid and brain correlates with severity of simian immunodeficiency virus encephalitis

Zink, M. C., Suryanarayana, K., Mankowski, J. L., Shen, A., Piatak, M., Spelman, J. P., Carter, D. L., Adams, R. J., Lifson, J. D. & Clements, J. E., Dec 1 1999, In : Journal of virology. 73, 12, p. 10480-10488 9 p.

Research output: Contribution to journalArticle

HIV and SIV induce alterations in CNS CaMKII expression and activation: A potential mechanism for cognitive impairment

Gupta, R. G., Kelly, K. M., Helke, K. L., Queen, S. E., Karper, J. M., Dorsey, J. L., Brice, A. K., Adams, R. J., Tarwater, P. M., Kolson, D. L. & Mankowski, J. L., Jun 2010, In : American Journal of Pathology. 176, 6, p. 2776-2784 9 p.

Research output: Contribution to journalArticle

Immune activation of platelets in response to serial phlebotomy in pigtailed macaques (Macaca nemestrina)

Vermillion, M. S., Lyons, C. E., Najarro, K. M., Adams, R. J. & Pate, K., Jul 1 2017, In : Comparative Medicine. 67, 4, p. 360-367 8 p.

Research output: Contribution to journalArticle

Immune Responses in Macaques to a Prototype Recombinant Adenovirus Live Oral Human Papillomavirus 16 Vaccine

Berg, M. G., Adams, R. J., Gambhira, R., Siracusa, M. C., Scott, A. L., Roden, R. B. S. & Ketner, G., Sep 2014, In : Clinical and Vaccine Immunology. 21, 9, p. 1224-1231 8 p.

Research output: Contribution to journalArticle

Intracerebral infusion of TNF-α and IL-6 failed to activate latent SIV infection in the brains of macaques inoculated with macrophage-tropic neuroadapted SIV(mac)

Joag, S. V., Adams, R. J., Pinson, D. M., Adany, I. & Narayan, O., Jan 1 1994, In : Journal of Leukocyte Biology. 56, 3, p. 353-357 5 p.

Research output: Contribution to journalArticle

Intrauterine mummified fetus in a rhesus monkey (Macaca mulatta)

Swindle, M. M., Adams, R. J. & Craft, C. F., Jan 1 1981, In : Journal of medical primatology. 10, 4-5, p. 269-273 5 p.

Research output: Contribution to journalArticle

In utero AAV-mediated gene transfer to rabbit pulmonary epithelium

Boyle, M. P., Enke, R. A., Adams, R. J., Guggino, W. B. & Zeitlin, P. L., Jan 1 2001, In : Molecular Therapy. 4, 2, p. 115-121 7 p.

Research output: Contribution to journalArticle

In vivo model of adeno-associated virus vector persistence and rescue

Afione, S. A., Conrad, C. K., Kearns, W. G., Chunduru, S., Adams, R., Reynolds, T. C., Guggino, W. B., Cutting, G. R., Carter, B. J. & Flotte, T. R., May 3 1996, In : Journal of virology. 70, 5, p. 3235-3241 7 p.

Research output: Contribution to journalArticle

Lentivirus induced arthritis in animals

Narayan, O., Zink, M. C., Gorrell, M., McEntee, M., Sharma, D. & Adams, R., Jan 1 1992, In : Journal of Rheumatology. 19, SUPPL. 32, p. 25-32 8 p.

Research output: Contribution to journalArticle

Limited in vivo production of type i or type III interferon after infection of macaques with vaccine or wild-type strains of measles virus

Shivakoti, R., Hauer, D., Adams, R. J., Lin, W. H. W., Duprex, W. P., De Swart, R. L. & Griffin, D. E., Apr 1 2015, In : Journal of Interferon and Cytokine Research. 35, 4, p. 292-301 10 p.

Research output: Contribution to journalArticle