Robert Kurman

2023

Risk of nonovarian cancer in a nationwide-based study of nearly 5000 women with borderline ovarian tumors in Denmark

Hannibal, C. G., Baandrup, L., Hertzum-Larsen, R., Vang, R., Kurman, R. J., Frederiksen, K. & Kjaer, S. K., Apr 1 2023, In: International Journal of Cancer. 152, 7, p. 1370-1377 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Ten-Year Follow-up of 9-Valent Human Papillomavirus Vaccine: Immunogenicity, Effectiveness, and Safety

Restrepo, J., Herrera, T., Samakoses, R., Reina, J. C., Pitisuttithum, P., Ulied, A., Bekker, L. G., Moreira, E. D., Olsson, S. E., Block, S. L., Hammes, L. S., Laginha, F., Ferenczy, A., Kurman, R., Ronnett, B. M., Stoler, M., Bautista, O., Gallagher, N. E., Salituro, G., Ye, M., & 1 othersLuxembourg, A., Oct 1 2023, In: Pediatrics. 152, 4, e2022060993.

Research output: Contribution to journal › Article › peer-review

2022

Efficacy, immunogenicity, and safety of a quadrivalent HPV vaccine in men: results of an open-label, long-term extension of a randomised, placebo-controlled, phase 3 trial

Goldstone, S. E., Giuliano, A. R., Palefsky, J. M., Lazcano-Ponce, E., Penny, M. E., Cabello, R. E., Moreira, E. D., Baraldi, E., Jessen, H., Ferenczy, A., Kurman, R., Ronnett, B. M., Stoler, M. H., Bautista, O., Das, R., Group, T., Luxembourg, A., Zhou, H. J. & Saah, A., Mar 2022, In: The Lancet Infectious Diseases. 22, 3, p. 413-425 13 p.

Research output: Contribution to journal › Article › peer-review

2020

Intratumoral Heterogeneity Accounts for Apparent Progression of Noninvasive Serous Tumors to Invasive Low-grade Serous Carcinoma: A Study of 30 Low-grade Serous Tumors of the Ovary in 18 Patients with Peritoneal Carcinomatosis

Seidman, J. D., Savage, J., Krishnan, J., Vang, R. & Kurman, R. J., Jan 1 2020, In: International Journal of Gynecological Pathology. 39, 1, p. 43-54 12 p.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Risk of specific types of ovarian cancer after borderline ovarian tumors in Denmark: A nationwide study

Hannibal, C. G., Frederiksen, K., Vang, R., Kurman, R. J. & Kjaer, S. K., Aug 15 2020, In: International Journal of Cancer. 147, 4, p. 990-995 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Two types of primary mucinous ovarian tumors can be distinguished based on their origin

Simons, M., Simmer, F., Bulten, J., Ligtenberg, M. J., Hollema, H., van Vliet, S., de Voer, R. M., Kamping, E. J., van Essen, D. F., Ylstra, B., Schwartz, L. E., Wang, Y., Massuger, L. F., Nagtegaal, I. D. & Kurman, R. J., Apr 1 2020, In: Modern Pathology. 33, 4, p. 722-733 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

2019

Clinicopathologic and Molecular Features of Paired Cases of Metachronous Ovarian Serous Borderline Tumor and Subsequent Serous Carcinoma

Chui, M. H., Xing, D., Zeppernick, F., Wang, Z. Q., Hannibal, C. G., Frederiksen, K., Kjaer, S. K., Cope, L., Kurman, R. J., Shih, I. M., Wang, T. L. & Vang, R., Nov 1 2019, In: American Journal of Surgical Pathology. 43, 11, p. 1462-1472 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

Comprehensive Surgical Staging in Stage 1 Clear Cell and Endometrioid Ovarian Carcinomas: Is it Necessary?

Padhy, R. R., Savage, J. & Kurman, R. J., May 1 2019, In: International Journal of Gynecological Pathology. 38, 3, p. 241-246 6 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Genomic landscape and evolutionary trajectories of ovarian cancer precursor lesions

Wu, R. C., Wang, P., Lin, S. F., Zhang, M., Song, Q., Chu, T., Wang, B. G., Kurman, R. J., Vang, R., Kinzler, K., Tomasetti, C., Jiao, Y., Shih, I. M. & Wang, T. L., May 2019, In: Journal of Pathology. 248, 1, p. 41-50 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

23 Scopus citations

Nine-valent HPV vaccine efficacy against related diseases and definitive therapy: comparison with historic placebo population

Giuliano, A. R., Joura, E. A., Garland, S. M., Huh, W. K., Iversen, O. E., Kjaer, S. K., Ferenczy, A., Kurman, R. J., Ronnett, B. M., Stoler, M. H., Bautista, O. M., Moeller, E., Ritter, M., Shields, C. & Luxembourg, A., Jul 2019, In: Gynecologic oncology. 154, 1, p. 110-117 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

22 Scopus citations

2018

Atypical Proliferative (Borderline) Serous Tumor in the Brain: A Case Report

Xing, D., Jenson, E., Zwick, C. A., Rodriguez, F. J. & Kurman, R. J., 2018, In: International Journal of Gynecological Pathology. 37, 1, p. 52-56 5 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Diagnosis of Endometrial Biopsies and Curettings: A Practical Approach, Third Edition

Murdock, T. A., Veras, E. F. T., Kurman, R. & Mazur, M. T., Jan 1 2018, Springer International Publishing. 378 p.

Research output: Book/Report › Book

Evaluation of liquid from the papanicolaou test and other liquid biopsies for the detection of endometrial and ovarian cancers

Wang, Y., Li, L., Douville, C., Cohen, J. D., Yen, T. T., Kinde, I., Sundfelt, K., Kjær, S. K., Hruban, R. H., Shih, I. M., Wang, T. L., Kurman, R. J., Springer, S., Ptak, J., Popoli, M., Schaefer, J., Silliman, N., Dobbyn, L., Tanner, E., Angarita, A., & 17 othersLycke, M., Jochumsen, K., Afsari, B., Danilova, L., Levine, D. A., Jardon, K., Zeng, X., Arseneau, J., Fu, L., Diaz, L. A., Karchin, R., Tomasetti, C., Kinzler, K. W., Vogelstein, B., Fader, A. N., Gilbert, L. & Papadopoulos, N., Aug 1 2018, In: Obstetrical and Gynecological Survey. 73, 8, p. 463-464 2 p.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

2 Scopus citations

Evaluation of liquid from the Papanicolaou test and other liquid biopsies for the detection of endometrial and ovarian cancers

Wang, Y., Li, L., Douville, C., Cohen, J. D., Yen, T. T., Kinde, I., Sundfelt, K., Kjær, S. K., Hruban, R. H., Shih, I. M., Wang, T. L., Kurman, R. J., Springer, S., Ptak, J., Popoli, M., Schaefer, J., Silliman, N., Dobbyn, L., Tanner, E. J., Angarita, A., & 17 othersLycke, M., Jochumsen, K., Afsari, B., Danilova, L., Levine, D. A., Jardon, K., Zeng, X., Arseneau, J., Fu, L., Diaz, L. A., Karchin, R., Tomasetti, C., Kinzler, K. W., Vogelstein, B., Fader, A. N., Gilbert, L. & Papadopoulos, N., Mar 21 2018, In: Science translational medicine. 10, 433, 8793.

Research output: Contribution to journal › Article › peer-review

Open Access

71 Scopus citations

Fallopian tube lesions in women at high risk for ovarian cancer: A multicenter study

Visvanathan, K., Shaw, P., May, B. J., Bahadirli-Talbott, A., Kaushiva, A., Risch, H., Narod, S., Wang, T. L., Parkash, V., Vang, R., Levine, D. A., Soslow, R., Kurman, R. & Shih, I. M., Nov 2018, In: Cancer Prevention Research. 11, 11, p. 697-705 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

24 Scopus citations

Human Papillomavirus Genotypes from Vaginal and Vulvar Intraepithelial Neoplasia in Females 15-26 Years of Age

Garland, S. M., Joura, E. A., Ault, K. A., Bosch, F. X., Brown, D. R., Castellsagué, X., Ferenczy, A., Ferris, D. G., Giuliano, A. R., Hernandez-Avila, M., Huh, W. K., Iversen, O. E., Kjaer, S. K., Kurman, R. J., Luna, J., Monsonego, J., Muñoz, N., Paavonen, J., Pitisuttihum, P., Ronnett, B. M., & 11 othersSteben, M., Stoler, M. H., Wheeler, C. M., Wiley, D. J., Perez, G., Saah, A. J., Luxembourg, A., Li, S., DiNubile, M. J., Wagner, M. & Velicer, C., 2018, In: Obstetrics and gynecology. 132, 2, p. 261-270 10 p.

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

2017

A nationwide study of ovarian serous borderline tumors in Denmark 1978–2002. Risk of recurrence, and development of ovarian serous carcinoma

Hannibal, C. G., Vang, R., Junge, J., Frederiksen, K., Kurman, R. J. & Kjaer, S. K., Jan 1 2017, In: Gynecologic oncology. 144, 1, p. 174-180 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

25 Scopus citations

Final efficacy, immunogenicity, and safety analyses of a nine-valent human papillomavirus vaccine in women aged 16–26 years: a randomised, double-blind trial

Huh, W. K., Joura, E. A., Giuliano, A. R., Iversen, O. E., de Andrade, R. P., Ault, K. A., Bartholomew, D., Cestero, R. M., Fedrizzi, E. N., Hirschberg, A. L., Mayrand, M. H., Ruiz-Sternberg, A. M., Stapleton, J. T., Wiley, D. J., Ferenczy, A., Kurman, R., Ronnett, B. M., Stoler, M. H., Cuzick, J., Garland, S. M., & 8 othersKjaer, S. K., Bautista, O. M., Haupt, R., Moeller, E., Ritter, M., Roberts, C. C., Shields, C. & Luxembourg, A., Nov 11 2017, In: The Lancet. 390, 10108, p. 2143-2159 17 p.

Research output: Contribution to journal › Article › peer-review

162 Scopus citations

High grade serous ovarian carcinomas originate in the fallopian tube

Labidi-Galy, S. I., Papp, E., Hallberg, D., Niknafs, N., Adleff, V., Noe, M., Bhattacharya, R., Novak, M., Jones, S., Phallen, J., Hruban, C. A., Hirsch, M. S., Lin, D. I., Schwartz, L., Maire, C. L., Tille, J. C., Bowden, M., Ayhan, A., Wood, L. D., Scharpf, R. B., & 6 othersKurman, R., Wang, T. L., Shih, I. M., Karchin, R., Drapkin, R. & Velculescu, V. E., Dec 1 2017, In: Nature communications. 8, 1, 1093.

Research output: Contribution to journal › Article › peer-review

Open Access

215 Scopus citations

Long-term behavior of serous borderline tumors subdivided into atypical proliferative tumors and noninvasive low-grade carcinomas: A population-based clinicopathologic study of 942 cases

Vang, R., Hannibal, C. G., Junge, J., Frederiksen, K., Kjaer, S. K. & Kurman, R. J., May 1 2017, In: American Journal of Surgical Pathology. 41, 6, p. 725-737 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

27 Scopus citations

Molecular analysis of high-grade serous ovarian carcinoma with and without associated serous tubal intra-epithelial carcinoma

Ducie, J., Dao, F., Considine, M., Olvera, N., Shaw, P. A., Kurman, R. J., Shih, I. M., Soslow, R. A., Cope, L. & Levine, D. A., Dec 1 2017, In: Nature communications. 8, 1, 990.

Research output: Contribution to journal › Article › peer-review

Open Access

65 Scopus citations

Parity, infertility, oral contraceptives, and hormone replacement therapy and the risk of ovarian serous borderline tumors: A nationwide case-control study

Rasmussen, E. L. K., Hannibal, C. G., Dehlendorff, C., Baandrup, L., Junge, J., Vang, R., Kurman, R. J. & Kjaer, S. K., Mar 1 2017, In: Gynecologic oncology. 144, 3, p. 571-576 6 p.

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

PD-L1 expression in human placentas and gestational trophoblastic diseases

Veras, E., Kurman, R. J., Wang, T. L. & Shih, I. M., 2017, In: International Journal of Gynecological Pathology. 36, 2, p. 146-153 8 p.

Research output: Contribution to journal › Article › peer-review

60 Scopus citations

Steroid hormone synthesis by the ovarian stroma surrounding epithelial ovarian tumors: A potential mechanism in ovarian tumorigenesis

Blanco, L. Z., Kuhn, E., Morrison, J. C., Bahadirli-Talbott, A., Smith-Sehdev, A. & Kurman, R. J., Apr 1 2017, In: Modern Pathology. 30, 4, p. 563-576 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

21 Scopus citations

2016

CCNE1 amplification and centrosome number abnormality in serous tubal intraepithelial carcinoma: Further evidence supporting its role as a precursor of ovarian high-grade serous carcinoma

Kuhn, E., Wang, T. L., Doberstein, K., Bahadirli-Talbott, A., Ayhan, A., Sehdev, A. S., Drapkin, R., Kurman, R. J. & Shih, I. M., Oct 1 2016, In: Modern Pathology. 29, 10, p. 1254-1261 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

41 Scopus citations

Diagnostic potential of tumor DNA from ovarian cyst fluid

Wang, Y., Sundfeldt, K., Mateoiu, C., Shih, I. M., Kurman, R. J., Schaefer, J., Silliman, N., Kinde, I., Springer, S., Foote, M., Kristjansdottir, B., James, N., Kinzler, K. W., Papadopoulos, N., Diaz, L. A. & Vogelstein, B., Jul 15 2016, In: eLife. 5, 2016JULY, e15175.

Research output: Contribution to journal › Article › peer-review

Open Access

21 Scopus citations

Molecular alterations of TP53 are a defining feature of ovarian high-grade serous carcinoma: A rereview of cases lacking tp53 mutations in the cancer genome atlas ovarian study

Vang, R., Levine, D. A., Soslow, R. A., Zaloudek, C., Shih, I. M. & Kurman, R. J., Jan 1 2016, In: International Journal of Gynecological Pathology. 35, 1, p. 48-55 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

78 Scopus citations

Seromucinous tumors of the ovary. What's in a name?

Kurman, R. J. & Shih, I. M., Jan 1 2016, In: International Journal of Gynecological Pathology. 35, 1, p. 78-81 4 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

35 Scopus citations

The dualistic model of ovarian carcinogenesis revisited, revised, and expanded

Kurman, R. J. & Shih, I. M., Apr 1 2016, In: American Journal of Pathology. 186, 4, p. 733-747 15 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

404 Scopus citations

2015

Clonality analysis of combined Brenner and mucinous tumours of the ovary reveals their monoclonal origin

Wang, Y., Wu, R. C., Shwartz, L. E., Haley, L., Lin, M. T., Shih, I. M. & Kurman, R. J., Oct 1 2015, In: Journal of Pathology. 237, 2, p. 146-151 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

26 Scopus citations

Gestational trophoblastic disease

Shih, I. M., Mazur, M. T. & Kurman, R. J., Jan 21 2015, Sternberg's Diagnostic Surgical Pathology: Sixth Edition. Wolters Kluwer Health Adis (ESP), Vol. 2-2.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

2 Scopus citations

Loss of ALDH1A1 expression is an early event in the pathogenesis of ovarian high-grade serous carcinoma

Chui, M. H., Wang, Y., Wu, R. C., Seidman, J., Kurman, R. J., Wang, T. L. & Shih, I. M., Mar 1 2015, In: Modern Pathology. 28, 3, p. 437-445 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Scopus citations

Molecular analysis of ovarian mucinous carcinoma reveals different cell of origins

Wang, Y., Shwartz, L. E., Anderson, D., Lin, M. T., Haley, L., Wu, R. C., Vang, R., Shih, I. M. & Kurman, R. J., 2015, In: Oncotarget. 6, 26, p. 22949-22958 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Re: Article by Natalie Banet and Robert J. Kurman: Two types of ovarian cortical inclusion cysts: Proposed origin and possible role in ovarian serous carcinogenesis; Int. J. Gynecol. Pathol. 2015;34:3-8

Kurman, R. J. & Banet, N., Apr 22 2015, In: International Journal of Gynecological Pathology. 34, 3, p. 304-305 2 p.

Research output: Contribution to journal › Letter › peer-review

1 Scopus citations

Two types of ovarian cortical inclusion cysts: Proposed origin and possible role in ovarian serous carcinogenesis

Banet, N. & Kurman, R. J., Jan 14 2015, In: International Journal of Gynecological Pathology. 34, 1, p. 3-8 6 p.

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

2014

A genetically engineered ovarian cancer mouse model based on fallopian tube transformation mimics human high-grade serous carcinoma development

Sherman-Baust, C. A., Kuhn, E., Valle, B. L., Shih, I. M., Kurman, R. J., Wang, T. L., Amano, T., Ko, M. S., Miyoshi, I., Araki, Y., Lehrmann, E., Zhang, Y., Becker, K. G. & Morin, P. J., Jul 2014, In: Journal of Pathology. 233, 3, p. 228-237 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

81 Scopus citations

A nationwide study of serous "borderline" ovarian tumors in Denmark 1978-2002: Centralized pathology review and overall survival compared with the general population

Hannibal, C. G., Vang, R., Junge, J., Frederiksen, K., Kjaerbye-Thygesen, A., Andersen, K. K., Tabor, A., Kurman, R. J. & Kjaer, S. K., Aug 2014, In: Gynecologic oncology. 134, 2, p. 267-273 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

40 Scopus citations

BRAF mutation is associated with a specific cell type with features suggestive of senescence in ovarian serous borderline (atypical proliferative) tumors

Zeppernick, F., Ardighieri, L., Hannibal, C. G., Vang, R., Junge, J., Kjaer, S. K., Zhang, R., Kurman, R. J. & Shih, I. M., 2014, In: American Journal of Surgical Pathology. 38, 12, p. 1603-1611 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

36 Scopus citations

Characterization of the immune cell repertoire in the normal fallopian tube

Ardighieri, L., Lonardi, S., Moratto, D., Facchetti, F., Shih, I. M., Vermi, W. & Kurman, R. J., 2014, In: International Journal of Gynecological Pathology. 33, 6, p. 581-591 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Scopus citations

Discovery of a cell: Reflections on the checkered history of intermediate trophoblast and update on its nature and pathologic manifestations

Kurman, R. J. & Shih, I. M., Jul 2014, In: International Journal of Gynecological Pathology. 33, 4, p. 339-347 9 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

13 Scopus citations

Erratum: Trophoblastic disease (International Journal of Gynecology and Obstetrics (2012) 119 (S130-S136))

Ngan, H. Y. S., Kohorn, E. I., Cole, L. A., Kurman, R. J., Kim, S. J., Lurain, J. R., Seckl, M. J., Sasaki, S. & Soper, J. T., Apr 2014, In: International Journal of Gynecology and Obstetrics. 125, 1, p. 93 1 p.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

Evaluation of microinvasion and lymph node involvement in ovarian serous borderline/atypical proliferative serous tumors: A morphologic and immunohistochemical analysis of 37 cases

Maniar, K. P., Wang, Y., Visvanathan, K., Shih, I. M. & Kurman, R. J., 2014, In: American Journal of Surgical Pathology. 38, 6, p. 743-755 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

19 Scopus citations

Ki-67 index as an ancillary tool in the differential diagnosis of proliferative endometrial lesions with secretory change

Gurda, G. T., Baras, A. S. & Kurman, R. J., Mar 1 2014, In: International Journal of Gynecological Pathology. 33, 2, p. 114-119 6 p.

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Mutational analysis of BRAF and KRAS in ovarian serous borderline (atypical proliferative) tumours and associated peritoneal implants

Ardighieri, L., Zeppernick, F., Hannibal, C. G., Vang, R., Cope, L., Junge, J., Kjaer, S. K., Kurman, R. J. & Shih, I. M., Jan 2014, In: Journal of Pathology. 232, 1, p. 16-22 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

38 Scopus citations

New views of ovarian carcinoma types: How will this change practice?

Köbel, M., Kurman, R. J. & Seidman, J. D., Jan 1 2014, Controversies in the Management of Gynecological Cancers. Springer London, p. 29-38 10 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

2 Scopus citations

Origin and pathogenesis of pelvic (Ovarian, Tubal, and Primary Peritoneal) serous carcinoma

Nik, N. N., Vang, R., Shih, I. M. & Kurman, R. J., 2014, In: Annual Review of Pathology: Mechanisms of Disease. 9, p. 27-45 19 p.

Research output: Contribution to journal › Article › peer-review

100 Scopus citations

Pathologic features associated with resolution of complex atypical hyperplasia and grade 1 endometrial adenocarcinoma after progestin therapy

Gunderson, C. C., Dutta, S., Fader, A. N., Maniar, K. P., Nasseri-Nik, N., Bristow, R. E., Diaz-Montes, T. P., Palermo, R. & Kurman, R. J., Jan 2014, In: Gynecologic oncology. 132, 1, p. 33-37 5 p.

Research output: Contribution to journal › Article › peer-review