Robert Weatherholtz

2024

Streptococcus pneumoniae serotype 3 population structure in the era of conjugate vaccines, 2001–2018

Cella, E., Sutcliffe, C. G., Grant, L. R., Tso, C., Weatherholtz, R. C., Littlepage, S., Becenti, L., Jubair, M., Simons, B. C., Harker-Jones, M., Reid, R., Yazzie, D., Santosham, M., O'brien, K. L., Hammitt, L. L. & Azarian, T., Mar 1 2024, In: Microbial genomics. 10, 3, 001196.

Research output: Contribution to journal › Article › peer-review

Open Access

2022

Carriage prevalence and genomic epidemiology of Staphylococcus aureus among Native American children and adults in the Southwestern USA

Cella, E., Sutcliffe, C. G., Tso, C., Paul, E., Ritchie, N., Colelay, J., Denny, E., Grant, L. R., Weatherholtz, R. C., Hammitt, L. L. & Azarian, T., 2022, In: Microbial genomics. 8, 5, 000806.

Research output: Contribution to journal › Article › peer-review

Open Access

Evaluation of indoor PM_2.5 concentrations in a Native American Community: a pilot study

Ji, N., Rule, A. M., Weatherholtz, R., Crosby, L., Bunnell, J. E., Orem, B., Reid, R., Santosham, M., Hammitt, L. L. & O’Brien, K. L., Jul 2022, In: Journal of Exposure Science and Environmental Epidemiology. 32, 4, p. 554-562 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2020

Frequency-dependent selection can forecast evolution in Streptococcus pneumoniae

Azarian, T., Martinez, P. P., Arnold, B. J., Qiu, X., Grant, L. R., Corander, J., Fraser, C., Croucher, N. J., Hammitt, L. L., Reid, R., Santosham, M., Weatherholtz, R. C., Bentley, S. D., O’Brien, K. L., Lipsitch, M. & Hanage, W. P., Oct 22 2020, In: PLoS biology. 18, 10, e3000878.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

High burden of staphylococcus aureus among native American individuals on the White Mountain Apache Tribal Lands

Sutcliffe, C. G., Grant, L. R., Reid, A., Douglass, G., Brown, L. B., Kellywood, K., Weatherholtz, R. C., Hubler, R., Quintana, A., Close, R., McAuley, J. B., Santosham, M., O’Brien, K. L. & Hammitt, L. L., Mar 1 2020, In: Open Forum Infectious Diseases. 7, 3, ofaa061.

Research output: Contribution to journal › Article › peer-review

Open Access

2019

Association of laboratory methods, colonization density, and age with detection of streptococcus pneumoniae in the nasopharynx

Sutcliffe, C. G., Grant, L. R., Cloessner, E., Klugman, K. P., Vidal, J. E., Reid, R., Colelay, J., Weatherholtz, R. C., Chochua, S., Jacobs, M. R., Santosham, M., O'Brien, K. L. & Hammitt, L. L., Dec 31 2019, In: American journal of epidemiology. 188, 12, p. 2110-2119 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Efficacy, safety and immunogenicity of a pneumococcal protein-based vaccine co-administered with 13-valent pneumococcal conjugate vaccine against acute otitis media in young children: A phase IIb randomized study

Hammitt, L. L., Campbell, J. C., Borys, D., Weatherholtz, R. C., Reid, R., Goklish, N., Moulton, L. H., Traskine, M., Song, Y., Swinnen, K., Santosham, M. & O'Brien, K. L., Dec 3 2019, In: Vaccine. 37, 51, p. 7482-7492 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

The burden of Staphylococcus aureus among Native Americans on the Navajo Nation

Sutcliffe, C. G., Grant, L. R., Reid, A., Douglass, G. K., Weatherholtz, R. C., Hubler, R., Quintana, A., Reid, R., Yazzie, D., Santosham, M., O’Brien, K. L. & Hammitt, L. L., Mar 2019, In: PloS one. 14, 3, e0213207.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

2018

The impact of serotype-specific vaccination on phylodynamic parameters of Streptococcus pneumoniae and the pneumococcal pan-genome

Azarian, T., Grant, L. R., Arnold, B. J., Hammitt, L. L., Reid, R., Santosham, M., Weatherholtz, R., Goklish, N., Thompson, C. M., Bentley, S. D., O’Brien, K. L., Hanage, W. P. & Lipsitch, M., Apr 2018, In: PLoS pathogens. 14, 4, e1006966.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Scopus citations

Water quality, availability, and acute gastroenteritis on the Navajo Nation - A pilot case-control study

Grytdal, S. P., Weatherholtz, R., Esposito, D. H., Campbell, J., Reid, R., Gregoricus, N., Schneeberger, C., Lusk, T. S., Xiao, L., Garrett, N., Bopp, C., Hammitt, L. L., Vinjé, J., Hill, V. R., O'Brien, K. L. & Hall, A. J., Dec 2018, In: Journal of Water and Health. 16, 6, p. 1018-1028 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

2017

Association of pneumococcal protein antigen serology with age and antigenic profile of colonizing isolates

Azarian, T., Grant, L. R., Georgieva, M., Hammitt, L. L., Reid, R., Bentley, S. D., Goldblatt, D., Santosham, M., Weatherholtz, R., Burbidge, P., Goklish, N., Thompson, C. M., Hanage, W. P., O'Brien, K. L. & Lipsitch, M., 2017, In: Journal of Infectious Diseases. 215, 5, p. 713-722 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

Identifying transmission routes of Streptococcus pneumoniae and sources of acquisitions in high transmission communities

Althouse, B. M., Hammitt, L. L., Grant, L., Wagner, B. G., Reid, R., Larzelere-Hinton, F., Weatherholtz, R., Klugman, K. P., Rodgers, G. L., O'Brien, K. L. & Hu, H., Oct 1 2017, In: Epidemiology and infection. 145, 13, p. 2750-2758 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

19 Scopus citations

Norovirus and sapovirus epidemiology and strain characteristics among navajo and apache infants

Grant, L. R., O'Brien, K. L., Weatherholtz, R. C., Reid, R., Goklish, N., Santosham, M., Parashar, U. & Vinjé, J., Jan 2017, In: PloS one. 12, 1, e0169491.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

2016

Impact of the 13-valent pneumococcal conjugate vaccine on pneumococcal carriage among American Indians

Grant, L. R., Hammitt, L. L., O'Brien, S. E., Jacobs, M. R., Donaldson, C., Weatherholtz, R. C., Reid, R., Santosham, M. & O'Brien, K. L., Aug 1 2016, In: Pediatric Infectious Disease Journal. 35, 8, p. 907-914 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

25 Scopus citations

Relating Pneumococcal Carriage among Children to Disease Rates among Adults before and after the Introduction of Conjugate Vaccines

Weinberger, D. M., Grant, L. R., Weatherholtz, R. C., Warren, J. L., O'Brien, K. L. & Hammitt, L. L., Jun 1 2016, In: American journal of epidemiology. 183, 11, p. 1055-1062 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

19 Scopus citations

2015

Efficacy of motavizumab for the prevention of respiratory syncytial virus disease in healthy Native American infants: A phase 3 randomised double-blind placebo-controlled trial

O'Brien, K. L., Chandran, A., Weatherholtz, R., Jafri, H. S., Griffin, M. P., Bellamy, T., Millar, E. V., Jensen, K. M., Harris, B. S., Reid, R., Moulton, L. H., Losonsky, G. A., Karron, R. A., Santosham, M., Donaldson, C., Eick-Cost, A., Perilla, M., Campbell, J., VanDeReit, D., Brown, L. B., & 6 othersGloyd, P. W., Seby, M., Brown, M. A., Candelaria, D., Foti, J. L. & Overturf, G., Dec 1 2015, In: The Lancet Infectious Diseases. 15, 12, p. 1398-1408 11 p.

Research output: Contribution to journal › Article › peer-review

90 Scopus citations

2014

Correction: Nasopharyngeal carriage and transmission of streptococcus pneumoniae in American Indian households after a decade of pneumococcal conjugate vaccine use (PLoS ONE (2014) 9, 1 (e79578) DOI: 10.1371/journal.pone. 0079578)

Mosser, J. F., Grant, L. R., Millar, E., Weatherholtz, R. C. & Jackson, D. M., Mar 26 2014, In: PloS one. 9, 3, e93878.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

4 Scopus citations

Erratum: Season drivers of pneumococcal disease incidence: Impact of bacterial carriage and viral activity (Clinical Infectious Diseases (2014) 58 (188-94))

Weinberger, D. M., Grant, L. R., Steiner, C. A., Weatherholtz, R., Santosham, M., Viboud, C. & O'Brien, K. L., Mar 2014, In: Clinical Infectious Diseases. 58, 6, p. 908 1 p.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

Nasopharyngeal carriage and transmission of Streptococcus pneumoniae in American Indian households after a decade of pneumococcal conjugate vaccine use

Mosser, J. F., Grant, L. R., Millar, E. V., Weatherholtz, R. C., Jackson, D. M., Beall, B., Craig, M. J., Reid, R., Santosham, M. & O'Brien, K. L., Jan 17 2014, In: PloS one. 9, 1, e79578.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Scopus citations

Seasonal drivers of pneumococcal disease incidence: Impact of bacterial carriage and viral activity

Weinberger, D. M., Grant, L. R., Steiner, C. A., Weatherholtz, R., Santosham, M., Viboud, C. & O'Brien, K. L., Jan 15 2014, In: Clinical Infectious Diseases. 58, 2, p. 188-194 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

49 Scopus citations

2013

A prospective study of agents associated with acute respiratory infection among young american indian children

Bhat, N., Tokarz, R., Jain, K., Haq, S., Weatherholtz, R., Chandran, A., Karron, R., Reid, R., Santosham, M., O'Brien, K. L. & Lipkin, W. I., Aug 2013, In: Pediatric Infectious Disease Journal. 32, 8, p. e324-e333

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

Comparative Immunogenicity of 7 and 13-Valent Pneumococcal Conjugate Vaccines and the Development of Functional Antibodies to Cross-Reactive Serotypes

Grant, L. R., O'Brien, S. E., Burbidge, P., Haston, M., Zancolli, M., Cowell, L., Johnson, M., Weatherholtz, R. C., Reid, R., Santosham, M., O'Brien, K. L. & Goldblatt, D., Sep 23 2013, In: PloS one. 8, 9, e74906.

Research output: Contribution to journal › Article › peer-review

Open Access

48 Scopus citations

Lack of nonspecific protection against all-cause nonrotavirus gastroenteritis by vaccination with orally administered rotavirus vaccine

Grant, L., Watt, J., Moulton, L., Weatherholtz, R., Reid, R., Santosham, M. & O'Brien, K., Jun 2013, In: Journal of pediatric gastroenterology and nutrition. 56, 6, p. 635-640 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Serotype-Specific Changes in Invasive Pneumococcal Disease after Pneumococcal Conjugate Vaccine Introduction: A Pooled Analysis of Multiple Surveillance Sites

Feikin, D. R., Kagucia, E. W., Loo, J. D., Link-Gelles, R., Puhan, M. A., Cherian, T., Levine, O. S., Whitney, C. G., O'Brien, K. L., Moore, M. R., Feikin, D. R., Link-Gelles, R., Cherian, T., Adegbola, R. A., Agocs, M., Ampofo, K., Andrews, N., Barton, T., Benito, J., Broome, C. V., & 79 othersBruce, M. G., Bulkow, L. R., Byington, C. L., Camou, T., Cook, H., Cotter, S., Dagan, R., de Wals, P., Deceuninck, G., Denham, B., Edwards, G., Eskola, J., Fitzgerald, M., Galanakis, E., Garcia-Gabarrot, G., Garcia-Garcia, J. J., Gene, A., Gomez, B., Heffernan, H., Hennessy, T. W., Heuberger, S., Hilty, M., Ingels, H., Jayasinghe, S., Kagucia, E. W., Kellner, J. D., Klein, N. P., Kormann-Klement, A., Kozakova, J., Krause, V., Kriz, P., Lambertsen, L., Lepoutre, A., Levine, O. S., Lipsitch, M., Loo, J. D., Lopez-Vega, M., Lovgren, M., Maraki, S., Mason, E. O., McIntyre, P. B., Menzies, R., Messina, A., Miller, E., Mintegi, S., Moore, M. R., Motlova, J., Moulton, L. H., Mühlemann, K., Muñoz-Almagro, C., O'Brien, K. L., Murdoch, D. R., Park, D. E., Puhan, M. A., Reingold, A. L., Sa-Leao, R., Sanyal, A., Smith, P. G., Spanjaard, L., Techasaensiri, C., Thompson, R. E., Thoon, K. C., Tyrrell, G. J., Valentiner-Branth, P., van der Ende, A., Vanderkooi, O. G., van der Linden, M. P. G., Varon, E., Verhaegen, J., Vestrheim, D. F., Vickers, I., von Gottberg, A., von Kries, R., Waight, P., Weatherholtz, R., Weiss, S., Whitney, C. G., Yee, A. & Zaidi, A. K. M., Sep 2013, In: PLoS medicine. 10, 9, e1001517.

Research output: Contribution to journal › Article › peer-review

Open Access

305 Scopus citations

2012

Efficacy of a pentavalent human-bovine reassortant rotavirus vaccine against rotavirus gastroenteritis among American Indian children

Grant, L. R., Watt, J. P., Weatherholtz, R. C., Moulton, L. H., Reid, R., Santosham, M. & O'Brien, K. L., Feb 2012, In: Pediatric Infectious Disease Journal. 31, 2, p. 184-188 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

Epidemiologic and clinical features of other enteric viruses associated with acute gastroenteritis in American Indian infants

Grant, L., Vinjé, J., Parashar, U., Watt, J., Reid, R., Weatherholtz, R., Santosham, M., Gentsch, J. & O'Brien, K., Jul 2012, In: Journal of Pediatrics. 161, 1, p. 110-115.e1

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Impact of more than a decade of pneumococcal conjugate vaccine use on carriage and invasive potential in native American communities

Scott, J. R., Millar, E. V., Lipsitch, M., Moulton, L. H., Weatherholtz, R., Perilla, M. J., Jackson, D. M., Beall, B., Craig, M. J., Reid, R., Santosham, M. & O'Brien, K. L., Jan 15 2012, In: Journal of Infectious Diseases. 205, 2, p. 280-288 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

79 Scopus citations

2011

Detection of G3P[3] and G3P[9] rotavirus strains in American Indian children with evidence of gene reassortment between human and animal rotaviruses

Grant, L., Esona, M., Gentsch, J., Watt, J., Reid, R., Weatherholtz, R., Santosham, M., Parashar, U. & O'Brien, K., Jul 2011, In: Journal of Medical Virology. 83, 7, p. 1288-1299 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

30 Scopus citations

2010

Invasive pneumococcal disease a decade after pneumococcal conjugate vaccine use in an american indian population at high risk for disease

Weatherholtz, R., Millar, E. V., Moulton, L. H., Reid, R., Rudolph, K., Santosham, M. & O'Brien, K. L., May 1 2010, In: Clinical Infectious Diseases. 50, 9, p. 1238-1246 9 p.

Research output: Contribution to journal › Article › peer-review

63 Scopus citations

2008

Randomized, controlled trial efficacy of pneumococcal conjugate vaccine against otitis media among navajo and white mountain apache infants

O'Brien, K. L., David, A. B., Chandran, A., Moulton, L. H., Reid, R., Weatherholtz, R. & Santosham, M., Jan 2008, In: Pediatric Infectious Disease Journal. 27, 1, p. 71-73 3 p.

Research output: Contribution to journal › Article › peer-review

Open Access

46 Scopus citations

2007

Contributions of Native Americans to the global control of infectious diseases

Santosham, M., Reid, R., Chandran, A., Millar, E. V., Watt, J. P., Weatherholtz, R., Donaldson, C., Croll, J., Moulton, L. H., Thompson, C. M., Siber, G. R. & O'Brien, K. L., Mar 22 2007, In: Vaccine. 25, 13, p. 2366-2374 9 p.

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Effect of pneumococcal conjugate vaccine on nasopharyngeal colonization among immunized and unimmunized children in a community-randomized trial

O'Brien, K. L., Millar, E. V., Zell, E. R., Bronsdon, M., Weatherholtz, R., Reid, R., Becenti, J., Kvamme, S., Whitney, C. G. & Santosham, M., 2007, In: Journal of Infectious Diseases. 196, 8, p. 1211-1220 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

185 Scopus citations

Predictors of pneumococcal conjugate vaccine immunogenicity among infants and toddlers in an American Indian PnCRM7 efficacy trial

O'Brien, K. L., Moïsi, J., Moulton, L. H., Madore, D., Eick, A., Reid, R., Weatherholtz, R., Millar, E., Hu, D., Hackell, J., Kohberger, R., Siber, G. & Santosham, M., Jul 1 2007, In: Journal of Infectious Diseases. 196, 1, p. 104-114 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

27 Scopus citations

2006

Evaluation of the indirect effects of a pneumococcal vaccine in a community-randomized study

Moulton, L. H., O'Brien, K. L., Reid, R., Weatherholtz, R., Santosham, M. & Siber, G. R., Aug 1 2006, In: Journal of biopharmaceutical statistics. 16, 4, p. 453-462 10 p.

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

2004

Epidemiology of invasive Streptococcus pneumoniae among Navajo children in the era before use of conjugate pneumococcal vaccines, 1989-1996

O'Brien, K. L., Shaw, J., Weatherholtz, R., Reid, R., Watt, J., Croll, J., Dagan, R., Parkinson, A. J. & Santosham, M., Aug 1 2004, In: American journal of epidemiology. 160, 3, p. 270-278 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

44 Scopus citations

Safety and immunogenicity of two octavalent pneumococcal conjugate vaccines in American Indian infants

Eick, A., Croll, J., Weatherholtz, R., Croll, L. & Santosham, M., Mar 12 2004, In: Vaccine. 22, 9-10, p. 1260-1264 5 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

2003

Efficacy and safety of seven-valent conjugate pneumococcal vaccine in American Indian children: Group randomised trial

O'Brien, K. L., Moulton, L. H., Reid, R., Weatherholtz, R., Oski, J., Brown, L., Kumar, G., Parkinson, A., Hu, D., Hackell, J., Chang, I., Kohberger, R., Siber, G. & Santosham, M., Aug 2 2003, In: Lancet. 362, 9381, p. 355-361 7 p.

Research output: Contribution to journal › Article › peer-review

314 Scopus citations

2002

Respiratory syncytial virus infection in Navajo and White Mountain Apache children.

Bockova, J., O'Brien, K. L., Oski, J., Croll, J., Reid, R., Weatherholtz, R. C., Santosham, M. & Karron, R. A., Aug 2002, In: Pediatrics. 110, 2 Pt 1, p. e20

Research output: Contribution to journal › Article › peer-review

38 Scopus citations

2001

Design of a group-randomized Streptococcus pneumoniae vaccine trial

Moulton, L. H., O'Brien, K. L., Kohberger, R., Chang, I., Reid, R., Weatherholtz, R., Hackell, J. G., Siber, G. R. & Santosham, M., 2001, In: Controlled clinical trials. 22, 4, p. 438-452 15 p.

Research output: Contribution to journal › Article › peer-review

48 Scopus citations

2000

Estimation of the indirect effect of Haemophilus influenzae type b conjugate vaccine in an American Indian population

Moulton, L. H., Chung, S. E., Croll, J., Reid, R., Weatherholtz, R. C. & Santosham, M., 2000, In: International journal of epidemiology. 29, 4, p. 753-756 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

51 Scopus citations

1994

Postlicensure effectiveness of the Haemophilus influenzae type b polysaccharide-Neisseria meningitidis outer-membrane protein complex conjugate vaccine among Navajo children

Harrison, L. H., Tajkowski, C., Croll, J., Reid, R., Hu, D., Brenneman, G., Weatherholtz, R. C. & Santosham, M., Oct 1994, In: The Journal of pediatrics. 125, 4, p. 571-576 6 p.

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Robert Weatherholtz

Research output

Search results