Robert B Scharpf

Associate Professor

19972020

Research output per year

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Research Output

2020

White blood cell and cell-free DNA analyses for detection of residual disease in gastric cancer

Leal, A., van Grieken, N. C. T., Palsgrove, D. N., Phallen, J., Medina, J. E., Hruban, C., Broeckaert, M. A. M., Anagnostou, V., Adleff, V., Bruhm, D. C., Canzoniero, J. V., Fiksel, J., Nordsmark, M., Warmerdam, F. A. R. M., Verheul, H. M. W., van Spronsen, D. J., Beerepoot, L. V., Geenen, M. M., Portielje, J. E. A., Jansen, E. P. M. & 11 others, van Sandick, J., Meershoek-Klein Kranenbarg, E., van Laarhoven, H. W. M., van der Peet, D. L., van de Velde, C. J. H., Verheij, M., Fijneman, R., Scharpf, R. B., Meijer, G. A., Cats, A. & Velculescu, V. E., Dec 1 2020, In : Nature communications. 11, 1, 525.

Research output: Contribution to journalArticle

Open Access
2019

Detection of de novo copy number deletions from targeted sequencing of trios

Fu, J. M., Leslie, E. J., Scott, A. F., Murray, J. C., Marazita, M. L., Beaty, T. H., Scharpf, R. B. & Ruczinski, I., Feb 15 2019, In : Bioinformatics. 35, 4, p. 571-578 8 p.

Research output: Contribution to journalArticle

Open Access

Detection of rare disease variants in extended pedigrees using RVS

Sherman, T., Fu, J., Scharpf, R. B., Bureau, A. & Ruczinski, I., Jul 15 2019, In : Bioinformatics. 35, 14, p. 2509-2511 3 p., bty976.

Research output: Contribution to journalArticle

Open Access

Dynamics of tumor and immune responses during immune checkpoint blockade in non–small cell lung cancer

Anagnostou, V., Forde, P. M., White, J. R., Niknafs, N., Hruban, C., Naidoo, J., Marrone, K., Ashok Sivakumar, I. K., Bruhm, D. C., Rosner, S., Phallen, J., Leal, A., Adleff, V., Smith, K. N., Cottrell, T. R., Rhymee, L., Palsgrove, D. N., Hann, C. L., Levy, B., Feliciano, J. & 16 others, Georgiades, C., Verde, F., Illei, P., Li, Q. K., Gabrielson, E., Brock, M. V., Isbell, J. M., Sauter, J. L., Taube, J., Scharpf, R. B., Karchin, R., Pardoll, D. M., Chaft, J. E., Hellmann, M. D., Brahmer, J. R. & Velculescu, V. E., Jan 1 2019, In : Cancer Research. 79, 6, p. 1214-1225 12 p.

Research output: Contribution to journalArticle

Open Access

Early noninvasive detection of response to targeted therapy in non–small cell lung cancer

Phallen, J., Leal, A., Woodward, B. D., Forde, P., Naidoo, J., Marrone, K., Brahmer, J., Fiksel, J., Medina, J. E., Cristiano, S., Palsgrove, D. N., Gocke, C., Bruhm, D. C., Keshavarzian, P., Adleff, V., Weihe, E., Anagnostou, V., Scharpf, R. B., Velculescu, V. E. & Husain, H., Jan 1 2019, In : Cancer Research. 79, 6, p. 1204-1213 10 p.

Research output: Contribution to journalArticle

Open Access

Genome-wide cell-free DNA fragmentation in patients with cancer

Cristiano, S., Leal, A., Phallen, J., Fiksel, J., Adleff, V., Bruhm, D. C., Jensen, S. Ø., Medina, J. E., Hruban, C., White, J. R., Palsgrove, D. N., Niknafs, N., Anagnostou, V., Forde, P., Naidoo, J., Marrone, K., Brahmer, J., Woodward, B. D., Husain, H., van Rooijen, K. L. & 16 others, Ørntoft, M. B. W., Madsen, A. H., van de Velde, C. J. H., Verheij, M., Cats, A., Punt, C. J. A., Vink, G. R., van Grieken, N. C. T., Koopman, M., Fijneman, R. J. A., Johansen, J. S., Nielsen, H. J., Meijer, G. A., Andersen, C. L., Scharpf, R. B. & Velculescu, V. E., Jun 20 2019, In : Nature. 570, 7761, p. 385-389 5 p.

Research output: Contribution to journalArticle

Intraductal Papillary Mucinous Neoplasms Arise From Multiple Independent Clones, Each With Distinct Mutations

Fischer, C. G., Beleva Guthrie, V., Braxton, A. M., Zheng, L., Wang, P., Song, Q., Griffin, J. F., Chianchiano, P. E., Hosoda, W., Niknafs, N., Springer, S., Dal Molin, M., Masica, D., Scharpf, R. B., Thompson, E. D., He, J., Wolfgang, C. L., Hruban, R. H., Roberts, N. J., Lennon, A. M. & 3 others, Jiao, Y., Karchin, R. & Wood, L. D., Oct 2019, In : Gastroenterology. 157, 4, p. 1123-1137.e22

Research output: Contribution to journalArticle

2018

Genome-Wide Association Study of Serum Fructosamine and Glycated Albumin in Adults Without Diagnosed Diabetes: Results From the Atherosclerosis Risk in Communities Study

Loomis, S. J., Li, M., Maruthur, N., Baldridge, A. S., North, K. E., Mei, H., Morrison, A., Carson, A. P., Pankow, J. S., Boerwinkle, E., Scharpf, R. B., Rasmussen-Torvik, L. J., Coresh, J., Duggal, P., Köttgen, A. & Selvin, E., Aug 1 2018, In : Diabetes. 67, 8, p. 1684-1696 13 p.

Research output: Contribution to journalArticle

Integrated Genomic, Epigenomic, and Expression Analyses of Ovarian Cancer Cell Lines

Papp, E., Hallberg, D., Konecny, G. E., Bruhm, D. C., Adleff, V., Noë, M., Kagiampakis, I., Palsgrove, D., Conklin, D., Kinose, Y., White, J. R., Press, M. F., Drapkin, R., Easwaran, H., Baylin, S. B., Slamon, D., Velculescu, V. E. & Scharpf, R. B., Nov 27 2018, In : Cell Reports. 25, 9, p. 2617-2633 17 p.

Research output: Contribution to journalArticle

Neoadjuvant PD-1 blockade in resectable lung cancer

Forde, P., Chaft, J. E., Smith, K., Anagnostou, V., Cottrell, T. R., Hellmann, M. D., Zahurak, M., Broderick, S., Yang, S. C., Jones, D. R., Battafarano, R. J., Velez, M. J., Rekhtman, N., Olah, Z., Verde, F., Naidoo, J., Marrone, K., Guo, H., Sidhom, J. W., Zhang, J. & 15 others, Caushi, J. X., Chan, H. Y., Scharpf, R. B., White, J., Gabrielson, E., Wang, H., Rosner, G., Rusch, V., Wolchok, J. D., Merghoub, T., Taube, J. M., Velculescu, V. E., Topalian, S., Brahmer, J. & Pardoll, A. M., May 24 2018, In : New England Journal of Medicine. 378, 21, p. 1976-1986 11 p.

Research output: Contribution to journalArticle

2017

Direct detection of early-stage cancers using circulating tumor DNA

Phallen, J., Sausen, M., Adleff, V., Leal, A., Hruban, C., White, J., Anagnostou, V., Fiksel, J., Cristiano, S., Papp, E., Speir, S., Reinert, T., Orntoft, M. B. W., Woodward, B. D., Murphy, D., Parpart-Li, S., Riley, D., Nesselbush, M., Sengamalay, N., Georgiadis, A. & 17 others, Li, Q. K., Madsen, M. R., Mortensen, F. V., Huiskens, J., Punt, C., Van Grieken, N., Fijneman, R., Meijer, G., Husain, H., Scharpf, R. B., Diaz, L. A., Jones, S., Angiuoli, S., Ørntoft, T., Nielsen, H. J., Andersen, C. L. & Velculescu, V. E., Aug 16 2017, In : Science translational medicine. 9, 403, eaan2415.

Research output: Contribution to journalArticle

Evolution of neoantigen landscape during immune checkpoint blockade in non-small cell lung cancer

Anagnostou, V., Smith, K., Forde, P., Niknafs, N., Bhattacharya, R., White, J., Zhang, T., Adleff, V., Phallen, J., Wali, N., Hruban, C., Guthrie, V. B., Rodgers, K., Naidoo, J., Kang, H., Sharfman, W., Georgiades, C. S., Verde, F., Illei, P. B., Li, Q. K. & 9 others, Gabrielson, E., Brock, M. V., Zahnow, C., Baylin, S. B., Scharpf, R. B., Brahmer, J., Karchin, R., Pardoll, A. M. & Velculescu, V. E., Mar 1 2017, In : Cancer Discovery. 7, 3, p. 264-276 13 p.

Research output: Contribution to journalArticle

GATA3 frameshift mutation promotes tumor growth in human luminal breast cancer cells and induces transcriptional changes seen in primary GATA3 mutant breast cancers

Gustin, J. P., Miller, J., Farag, M., Marc Rosen, D., Thomas, M., Scharpf, R. B. & Lauring, J., Jan 1 2017, In : Oncotarget. 8, 61, p. 103415-103427 13 p.

Research output: Contribution to journalArticle

Genome-wide association of copy number polymorphisms and kidney function

Li, M., Carey, J., Cristiano, S., Susztak, K., Coresh, J., Boerwinkle, E., Kao, W. H. L., Beaty, T. L., Köttgen, A. & Scharpf, R. B., Jan 1 2017, In : PLoS One. 12, 1, e0170815.

Research output: Contribution to journalArticle

High grade serous ovarian carcinomas originate in the fallopian tube

Labidi-Galy, S. I., Papp, E., Hallberg, D., Niknafs, N., Adleff, V., Noe, M., Bhattacharya, R., Novak, M., Jones, S., Phallen, J., Hruban, C. A., Hirsch, M. S., Lin, D. I., Schwartz, L., Maire, C. L., Tille, J. C., Bowden, M., Ayhan, A., Wood, L. D., Scharpf, R. B. & 6 others, Kurman, R. J., Wang, T-L., Shih, I. M., Karchin, R., Drapkin, R. & Velculescu, V. E., Dec 1 2017, In : Nature Communications. 8, 1, 1093.

Research output: Contribution to journalArticle

The loss of GSTM1 associates with kidney failure and heart failure

Tin, A., Scharpf, R. B., Estrella, M. M., Yu, B., Grove, M. L., Chang, P. P., Matsushita, K., Köttgen, A., Arking, D., Boerwinkle, E., Le, T. H., Coresh, J. & Grams, M., Nov 1 2017, In : Journal of the American Society of Nephrology. 28, 11, p. 3345-3352 8 p.

Research output: Contribution to journalArticle

Whole exome association of rare deletions in multiplex oral cleft families

Fu, J., Beaty, T. L., Scott, A. F., Hetmanski, J., Parker, M. M., Wilson, J. E. B., Marazita, M. L., Mangold, E., Albacha-Hejazi, H., Murray, J. C., Bureau, A., Carey, J., Cristiano, S., Ruczinski, I. & Scharpf, R. B., Jan 1 2017, In : Genetic Epidemiology. 41, 1, p. 61-69 9 p.

Research output: Contribution to journalArticle

2016

Hemizygous deletion on chromosome 3p26.1 is associated with heavy smoking among African American subjects in the COPDGene study

Begum, F., Ruczinski, I., Hokanson, J. E., Lutz, S. M., Parker, M. M., Cho, M. H., Hetmanski, J. B., Scharpf, R. B., Crapo, J. D., Silverman, E. K. & Beaty, T. H., Oct 2016, In : PloS one. 11, 10, e0164134.

Research output: Contribution to journalArticle

Identifying a Deletion Affecting Total Lung Capacity Among Subjects in the COPDGene Study Cohort

Begum, F., Ruczinski, I., Li, S., Silverman, E. K., Cho, M. H., Lynch, D. A., Curran-Everett, D., Crapo, J., Scharpf, R. B., Parker, M. M., Hetmanski, J. B. & Beaty, T. H., Jan 1 2016, In : Genetic epidemiology. 40, 1, p. 81-88 8 p.

Research output: Contribution to journalArticle

2015

A genome-wide study of inherited deletions identified two regions associated with nonsyndromic isolated oral clefts

Younkin, S. G., Scharpf, R. B., Schwender, H., Parker, M. M., Scott, A. F., Marazita, M. L., Beaty, T. H. & Ruczinski, I., Jan 1 2015, In : Birth Defects Research Part A - Clinical and Molecular Teratology. 103, 4, p. 276-283 8 p.

Research output: Contribution to journalArticle

Clinical implications of genomic alterations in the tumour and circulation of pancreatic cancer patients

Sausen, M., Phallen, J., Adleff, V., Jones, S., Leary, R. J., Barrett, M. T., Anagnostou, V., Parpart-Li, S., Murphy, D., Li, Q. K., Hruban, C. A., Scharpf, R. B., White, J. R., O'Dwyer, P. J., Allen, P. J., Eshleman, J., Thompson, C. B., Klimstra, D. S., Linehan, D. C., Maitra, A. & 6 others, Hruban, R. H., Diaz, L. A., Von Hoff, D. D., Johansen, J. S., Drebin, J. A. & Velculescu, V. E., Jul 7 2015, In : Nature Communications. 6, 7686.

Research output: Contribution to journalArticle

NDRG1 links p53 with proliferation-mediated centrosome homeostasis and genome stability

Croessmann, S., Wong, H. Y., Zabransky, D. J., Chu, D., Mendonca, J., Sharmaa, A., Mohseni, M., Rosen, D. M., Scharpf, R. B., Cidado, J., Cochran, R. L., Parsons, H. A., Dalton, W. B., Erlanger, B., Button, B., Cravero, K., Kyker-Snowman, K., Beaver, J. A., Kachhap, S., Hurley, P. J. & 2 others, Lauring, J. & Park, B. H., Sep 15 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 37, p. 11583-11588 6 p.

Research output: Contribution to journalArticle

The genomic landscape of response to EGFR blockade in colorectal cancer

Bertotti, A., Papp, E., Jones, S., Adleff, V., Anagnostou, V., Lupo, B., Sausen, M., Phallen, J., Hruban, C. A., Tokheim, C., Niknafs, N., Nesselbush, M., Lytle, K., Sassi, F., Cottino, F., Migliardi, G., Zanella, E. R., Ribero, D., Russolillo, N., Mellano, A. & 15 others, Muratore, A., Paraluppi, G., Salizzoni, M., Marsoni, S., Kragh, M., Lantto, J., Cassingena, A., Li, Q. K., Karchin, R., Scharpf, R., Sartore-Bianchi, A., Siena, S., Diaz, L. A., Trusolino, L. & Velculescu, V. E., Oct 8 2015, In : Nature. 526, 7572, p. 263-267 5 p.

Research output: Contribution to journalArticle

2014

A genome-wide study of de novo deletions identifies a candidate locus for non-syndromic isolated cleft lip/palate risk

Younkin, S. G., Scharpf, R. B., Schwender, H., Parker, M. M., Scott, A. F., Marazita, M. L., Beaty, T. H. & Ruczinski, I., Feb 14 2014, In : BMC genetics. 15, 24.

Research output: Contribution to journalArticle

Characterization of the genomic architecture and mutational spectrum of a small cell prostate carcinoma

Scott, A. F., Mohr, D. W., Ling, H., Scharpf, R. B., Zhang, P. & Liptak, G. S., Jan 1 2014, In : Genes. 5, 2, p. 366-384 19 p.

Research output: Contribution to journalArticle

Copy number polymorphisms near SLC2A9 are associated with serum uric acid concentrations

Scharpf, R. B., Mireles, L., Yang, Q., Köttgen, A., Ruczinski, I., Susztak, K., Halper-Stromberg, E., Tin, A., Cristiano, S., Chakravarti, A., Boerwinkle, E., Fox, C. S., Coresh, J. & Linda Kao, W. H., Jul 9 2014, In : BMC genetics. 15, 81.

Research output: Contribution to journalArticle

Detecting Disease Variants in Case-Parent Trio Studies Using the Bioconductor Software Package trio

Schwender, H., Li, Q., Neumann, C., Taub, M. A., Younkin, S. G., Berger, P., Scharpf, R. B., Beaty, T. H. & Ruczinski, I., Sep 1 2014, In : Genetic epidemiology. 38, 6, p. 516-522 7 p.

Research output: Contribution to journalArticle

MACROD2 overexpression mediates estrogen independent growth and tamoxifen resistance in breast cancers

Mohseni, M., Cidado, J., Croessmann, S., Cravero, K., Cimino-Mathews, A., Wong, H. Y., Scharpf, R., Zabransky, D. J., Abukhdeir, A. M., Garay, J. P., Wang, G. M., Beaver, J. A., Cochran, R. L., Blair, B. G., Rosen, D. M., Erlanger, B., Argani, P., Hurley, P. J., Lauring, J. & Park, B. H., Dec 9 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 49, p. 17606-17611 6 p.

Research output: Contribution to journalArticle

2012

Detectable clonal mosaicism from birth to old age and its relationship to cancer

Laurie, C. C., Laurie, C. A., Rice, K., Doheny, K. F., Zelnick, L. R., McHugh, C. P., Ling, H., Hetrick, K. N., Pugh, E. W., Amos, C., Wei, Q., Wang, L. E., Lee, J. E., Barnes, K. C., Hansel, N. N., Mathias, R., Daley, D., Beaty, T. H., Scott, A. F., Ruczinski, I. & 53 others, Scharpf, R. B., Bierut, L. J., Hartz, S. M., Landi, M. T., Freedman, N. D., Goldin, L. R., Ginsburg, D., Li, J., Desch, K. C., Strom, S. S., Blot, W. J., Signorello, L. B., Ingles, S. A., Chanock, S. J., Berndt, S. I., Le Marchand, L., Henderson, B. E., Monroe, K. R., Heit, J. A., De Andrade, M., Armasu, S. M., Regnier, C., Lowe, W. L., Hayes, M. G., Marazita, M. L., Feingold, E., Murray, J. C., Melbye, M., Feenstra, B., Kang, J. H., Wiggs, J. L., Jarvik, G. P., McDavid, A. N., Seshan, V. E., Mirel, D. B., Crenshaw, A., Sharopova, N., Wise, A., Shen, J., Crosslin, D. R., Levine, D. M., Zheng, X., Udren, J. I., Bennett, S., Nelson, S. C., Gogarten, S. M., Conomos, M. P., Heagerty, P., Manolio, T., Pasquale, L. R., Haiman, C. A., Caporaso, N. & Weir, B. S., Jun 1 2012, In : Nature genetics. 44, 6, p. 642-650 9 p.

Research output: Contribution to journalArticle

Fast detection of de novo copy number variants from SNP arrays for case-parent trios

Scharpf, R. B., Beaty, T. H., Schwender, H., Younkin, S. G., Scott, A. F. & Ruczinski, I., Dec 12 2012, In : BMC Bioinformatics. 13, 1, 330.

Research output: Contribution to journalArticle

2011

A multilevel model to address batch effects in copy number estimation using SNP arrays

Scharpf, R. B., Ruczinski, I., Carvalho, B., Doan, B., Chakravarti, A. & Irizarry, R. A., Jan 1 2011, In : Biostatistics. 12, 1, p. 33-50 18 p.

Research output: Contribution to journalArticle

Influence of Diabetes Mellitus Type 2 and Prolonged Estrogen Exposure on Risk of Breast Cancer Among Women in Armenia

Khachatryan, L., Scharpf, R. & Kagan, S., Dec 1 2011, In : Health care for women international. 32, 11, p. 953-971 19 p.

Research output: Contribution to journalArticle

Performance assessment of copy number microarray platforms using a spike-in experiment

Halper-Stromberg, E., Frelin, L., Ruczinski, I., Scharpf, R., Jie, C., Carvalho, B., Hao, H., Hetrick, K., Jedlicka, A., Dziedzic, A., Doheny, K., Scott, A. F., Baylin, S., Pevsner, J., Spencer, F. & Irizarry, R. A., Apr 1 2011, In : Bioinformatics. 27, 8, p. 1052-1060 9 p., btr106.

Research output: Contribution to journalArticle

Using the r package crlmm for genotyping and copy number estimation

Scharpf, R. B., Irizarry, R. A., Ritchie, M. E., Carvalho, B. & Ruczinski, I., Jan 1 2011, In : Journal of Statistical Software. 40, 12, p. 1-32 32 p.

Research output: Contribution to journalArticle

Open Access
2010

Cross-platform comparison of two pancreatic cancer phenotypes

Scharpf, R. B., Iacobuzio-Donahue, C. A., Cope, L., Ruczinski, I., Garrett-Mayer, E., Lakkur, S., Campagna, D. & Parmigiani, G., Dec 30 2010, In : Cancer Informatics. 9, p. 257-264 8 p.

Research output: Contribution to journalArticle

R classes and methods for SNP array data.

Scharpf, R. B. & Ruczinski, I., 2010, In : Methods in molecular biology (Clifton, N.J.). 593, p. 67-79 13 p.

Research output: Contribution to journalArticle

Tackling the widespread and critical impact of batch effects in high-throughput data

Leek, J. T., Scharpf, R. B., Bravo, H. C., Simcha, D., Langmead, B., Johnson, W. E., Geman, D., Baggerly, K. & Irizarry, R. A., Oct 14 2010, In : Nature Reviews Genetics. 11, 10, p. 733-739 7 p.

Research output: Contribution to journalReview article

2009

A Bayesian model for cross-study differential gene expression

Scharpf, R. B., Tjelmeland, H., Parmigiani, G. & Nobel, A. B., Dec 1 2009, In : Journal of the American Statistical Association. 104, 488, p. 1295-1310 16 p.

Research output: Contribution to journalArticle

Genome-wide association study of blood pressure and hypertension

Levy, D., Ehret, G. B., Rice, K., Verwoert, G. C., Launer, L. J., Dehghan, A., Glazer, N. L., Morrison, A. C., Johnson, A. D., Aspelund, T., Aulchenko, Y., Lumley, T., Köttgen, A., Vasan, R. S., Rivadeneira, F., Eiriksdottir, G., Guo, X., Arking, D. E., Mitchell, G. F., Mattace-Raso, F. U. S. & 24 others, Smith, A. V., Taylor, K., Scharpf, R. B., Hwang, S. J., Sijbrands, E. J. G., Bis, J., Harris, T. B., Ganesh, S. K., O'Donnell, C. J., Hofman, A., Rotter, J. I., Coresh, J., Benjamin, E. J., Uitterlinden, A. G., Heiss, G., Fox, C. S., Witteman, J. C. M., Boerwinkle, E., Wang, T. J., Gudnason, V., Larson, M. G., Chakravarti, A., Psaty, B. M. & Van Duijn, C. M., Jun 1 2009, In : Nature genetics. 41, 6, p. 677-687 11 p.

Research output: Contribution to journalArticle

Multiple loci associated with indices of renal function and chronic kidney disease

Köttgen, A., Glazer, N. L., Dehghan, A., Hwang, S. J., Katz, R., Li, M., Yang, Q., Gudnason, V., Launer, L. J., Harris, T. B., Smith, A. V., Arking, D. E., Astor, B. C., Boerwinkle, E., Ehret, G. B., Ruczinski, I., Scharpf, R. B., Ida Chen, Y. D., De Boer, I. H., Haritunians, T. & 19 others, Lumley, T., Sarnak, M., Siscovick, D., Benjamin, E. J., Levy, D., Upadhyay, A., Aulchenko, Y. S., Hofman, A., Rivadeneira, F., Uitterlinden, A. G., Van Duijn, C. M., Chasman, D. I., Paré, G., Ridker, P. M., Kao, W. H. L., Witteman, J. C., Coresh, J., Shlipak, M. G. & Fox, C. S., Jun 1 2009, In : Nature genetics. 41, 6, p. 712-717 6 p.

Research output: Contribution to journalArticle

Processing and analyzing Affymetrix SNP chips with Bioconductor

Carvalho, B., Irizarry, R. A., Scharpf, R. B. & Carey, V. J., Nov 24 2009, In : Statistics in Biosciences. 1, 2, p. 160-180 21 p.

Research output: Contribution to journalReview article

Rejoinder

Scharpf, R. B., Tjelmeland., H., Parmigiani., G. & Nobel, A. B., Dec 1 2009, In : Journal of the American Statistical Association. 104, 488, p. 1318-1323 6 p.

Research output: Contribution to journalArticle

2008

Hidden Markov models for the assessment of chromosomal alterations using high-throughput SNP arrays

Scharpf, R. B., Parmigiani, G., Pevsner, J. & Ruczinski, I., Jun 1 2008, In : Annals of Applied Statistics. 2, 2, p. 687-713 27 p.

Research output: Contribution to journalArticle

2007

Pre-processing Agilent microarray data

Zahurak, M., Parmigiani, G., Yu, W., Scharpf, R. B., Berman, D., Schaeffer, E., Shabbeer, S. & Cope, L., May 1 2007, In : BMC Bioinformatics. 8, 142.

Research output: Contribution to journalArticle

SNPchip: R classes and methods for SNP array data

Scharpf, R. B., Ting, J. C., Pevsner, J. & Ruczinski, I., Mar 1 2007, In : Bioinformatics. 23, 5, p. 627-628 2 p.

Research output: Contribution to journalArticle

When should one subtract background fluorescence in 2-color microarrays?

Scharpf, R. B., Iacobuzio-Donahue, C. A., Sneddon, J. B. & Parmigiani, G., Oct 1 2007, In : Biostatistics. 8, 4, p. 695-707 13 p.

Research output: Contribution to journalArticle

2005

Regulation of platelet granule exocytosis by S-nitrosylation

Morrell, C. N., Matsushita, K., Chiles, K., Scharpf, R. B., Yamakuchi, M., Mason, R. J. A., Bergmeier, W., Mankowski, J. L., Baldwin, W. M., Faraday, N. & Lowenstein, C. J., Mar 8 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 10, p. 3782-3787 6 p.

Research output: Contribution to journalArticle

2004

Platelet gene polymorphisms and cardiac risk assessment in vascular surgical patients

Faraday, N., Martinez, E. A., Scharpf, R. B., Kasch-Semenza, L., Dorman, T., Pronovost, P. J., Perler, B., Gerstenblith, G., Bray, P. F. & Fleisher, L. A., Dec 1 2004, In : Anesthesiology. 101, 6, p. 1291-1297 7 p.

Research output: Contribution to journalArticle

2003

Statistical modeling and visualization of molecular profiles in cancer

Scharpf, R., Garrett, E. S., Hu, J. & Parmigiani, G., Mar 1 2003, In : BioTechniques. 34, 3 SUPPL., p. S22-S29

Research output: Contribution to journalArticle