Robert B Scharpf

Associate Professor

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Single Nucleotide Polymorphism Medicine & Life Sciences
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Neoplasms Medicine & Life Sciences
Genes Chemical Compounds
Genome Medicine & Life Sciences
Genome-Wide Association Study Medicine & Life Sciences
Blood Platelets Medicine & Life Sciences
Microarrays Chemical Compounds

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Research Output 1997 2018

Genome-Wide Association Study of Serum Fructosamine and Glycated Albumin in Adults Without Diagnosed Diabetes: Results From the Atherosclerosis Risk in Communities Study

Loomis, S. J., Li, M., Maruthur, N., Baldridge, A. S., North, K. E., Mei, H., Morrison, A., Carson, A. P., Pankow, J. S., Boerwinkle, E., Scharpf, R. B., Rasmussen-Torvik, L. J., Coresh, J., Duggal, P., Köttgen, A. & Selvin, E., Aug 1 2018, In : Diabetes. 67, 8, p. 1684-1696 13 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Serum Albumin
Single Nucleotide Polymorphism

Integrated Genomic, Epigenomic, and Expression Analyses of Ovarian Cancer Cell Lines

Papp, E., Hallberg, D., Konecny, G. E., Bruhm, D. C., Adleff, V., Noë, M., Kagiampakis, I., Palsgrove, D., Conklin, D., Kinose, Y., White, J. R., Press, M. F., Drapkin, R., Easwaran, H., Baylin, S. B., Slamon, D., Velculescu, V. E. & Scharpf, R. B., Nov 27 2018, In : Cell Reports. 25, 9, p. 2617-2633 17 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Mitogen-Activated Protein Kinase Kinases

Neoadjuvant PD-1 blockade in resectable lung cancer

Forde, P., Chaft, J. E., Smith, K., Anagnostou, V., Cottrell, T. R., Hellmann, M. D., Zahurak, M., Broderick, S., Yang, S. C., Jones, D. R., Battafarano, R. J., Velez, M. J., Rekhtman, N., Olah, Z., Verde, F., Naidoo, J., Marrone, K., Guo, H., Sidhom, J. W., Zhang, J. & 15 othersCaushi, J. X., Chan, H. Y., Scharpf, R. B., White, J., Gabrielson, E., Wang, H., Rosner, G., Rusch, V., Wolchok, J. D., Merghoub, T., Taube, J. M., Velculescu, V. E., Topalian, S., Brahmer, J. & Pardoll, A. M., May 24 2018, In : New England Journal of Medicine. 378, 21, p. 1976-1986 11 p.

Research output: Contribution to journalArticle

Lung Neoplasms
Clone Cells
Non-Small Cell Lung Carcinoma

Direct detection of early-stage cancers using circulating tumor DNA

Phallen, J., Sausen, M., Adleff, V., Leal, A., Hruban, C., White, J., Anagnostou, V., Fiksel, J., Cristiano, S., Papp, E., Speir, S., Reinert, T., Orntoft, M. B. W., Woodward, B. D., Murphy, D., Parpart-Li, S., Riley, D., Nesselbush, M., Sengamalay, N., Georgiadis, A. & 17 othersLi, Q. K., Madsen, M. R., Mortensen, F. V., Huiskens, J., Punt, C., Van Grieken, N., Fijneman, R., Meijer, G., Husain, H., Scharpf, R. B., Diaz, L. A., Jones, S., Angiuoli, S., Ørntoft, T., Nielsen, H. J., Andersen, C. L. & Velculescu, V. E., Aug 16 2017, In : Science Translational Medicine. 9, 403, eaan2415.

Research output: Contribution to journalArticle

Early Detection of Cancer
High-Throughput Nucleotide Sequencing

Evolution of neoantigen landscape during immune checkpoint blockade in non-small cell lung cancer

Anagnostou, V., Smith, K., Forde, P., Niknafs, N., Bhattacharya, R., White, J., Zhang, T., Adleff, V., Phallen, J., Wali, N., Hruban, C., Guthrie, V. B., Rodgers, K., Naidoo, J., Kang, H., Sharfman, W., Georgiades, C. S., Verde, F., Illei, P. B., Li, Q. K. & 9 othersGabrielson, E., Brock, M. V., Zahnow, C., Baylin, S. B., Scharpf, R. B., Brahmer, J., Karchin, R., Pardoll, A. M. & Velculescu, V. E., Mar 1 2017, In : Cancer Discovery. 7, 3, p. 264-276 13 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
T-Cell Antigen Receptor