Robert B Scharpf

Associate Professor

19972019
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Fingerprint Dive into the research topics where Robert B Scharpf is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 2 Similar Profiles
Single Nucleotide Polymorphism Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
DNA Copy Number Variations Medicine & Life Sciences
Genome Medicine & Life Sciences
Genome-Wide Association Study Medicine & Life Sciences
DNA Medicine & Life Sciences
Software Medicine & Life Sciences
Genes Medicine & Life Sciences

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Research Output 1997 2019

Detection of de novo copy number deletions from targeted sequencing of trios

Fu, J. M., Leslie, E. J., Scott, A. F., Murray, J. C., Marazita, M. L., Beaty, T. L., Scharpf, R. B. & Ruczinski, I., Feb 15 2019, In : Bioinformatics. 35, 4, p. 571-578 8 p.

Research output: Contribution to journalArticle

Open Access
Formal methods
Deletion
Sequencing
Scalability
Minimum Distance

Detection of rare disease variants in extended pedigrees using RVS

Sherman, T., Fu, J., Scharpf, R. B., Bureau, A. & Ruczinski, I., Jul 15 2019, In : Bioinformatics. 35, 14, p. 2509-2511 3 p., bty976.

Research output: Contribution to journalArticle

Open Access
Pedigree
Rare Diseases
Software
Linkage
Bioinformatics

Dynamics of tumor and immune responses during immune checkpoint blockade in non–small cell lung cancer

Anagnostou, V., Forde, P. M., White, J. R., Niknafs, N., Hruban, C., Naidoo, J., Marrone, K., Ashok Sivakumar, I. K., Bruhm, D. C., Rosner, S., Phallen, J., Leal, A., Adleff, V., Smith, K. N., Cottrell, T. R., Rhymee, L., Palsgrove, D. N., Hann, C. L., Levy, B., Feliciano, J. & 16 others, Georgiades, C., Verde, F., Illei, P., Li, Q. K., Gabrielson, E., Brock, M. V., Isbell, J. M., Sauter, J. L., Taube, J., Scharpf, R. B., Karchin, R., Pardoll, D. M., Chaft, J. E., Hellmann, M. D., Brahmer, J. R. & Velculescu, V. E., Jan 1 2019, In : Cancer Research. 79, 6, p. 1214-1225 12 p.

Research output: Contribution to journalArticle

Open Access
Non-Small Cell Lung Carcinoma
DNA
Neoplasms
Therapeutics
Confidence Intervals

Early noninvasive detection of response to targeted therapy in non–small cell lung cancer

Phallen, J., Leal, A., Woodward, B. D., Forde, P., Naidoo, J., Marrone, K., Brahmer, J., Fiksel, J., Medina, J. E., Cristiano, S., Palsgrove, D. N., Gocke, C., Bruhm, D. C., Keshavarzian, P., Adleff, V., Weihe, E., Anagnostou, V., Scharpf, R. B., Velculescu, V. E. & Husain, H., Jan 1 2019, In : Cancer Research. 79, 6, p. 1204-1213 10 p.

Research output: Contribution to journalArticle

Open Access
Non-Small Cell Lung Carcinoma
DNA
Neoplasms
Circulating Neoplastic Cells
Therapeutics

Genome-wide cell-free DNA fragmentation in patients with cancer

Cristiano, S., Leal, A., Phallen, J., Fiksel, J., Adleff, V., Bruhm, D. C., Jensen, S. Ø., Medina, J. E., Hruban, C., White, J. R., Palsgrove, D. N., Niknafs, N., Anagnostou, V., Forde, P., Naidoo, J., Marrone, K., Brahmer, J., Woodward, B. D., Husain, H., van Rooijen, K. L. & 16 others, Ørntoft, M. B. W., Madsen, A. H., van de Velde, C. J. H., Verheij, M., Cats, A., Punt, C. J. A., Vink, G. R., van Grieken, N. C. T., Koopman, M., Fijneman, R. J. A., Johansen, J. S., Nielsen, H. J., Meijer, G. A., Andersen, C. L., Scharpf, R. B. & Velculescu, V. E., Jun 20 2019, In : Nature. 570, 7761, p. 385-389 5 p.

Research output: Contribution to journalLetter

DNA Fragmentation
Genome
DNA
Neoplasms
Bile Duct Neoplasms