Robert B Scharpf

Assistant Professor

School of Medicine

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3 Similar Profiles

Single Nucleotide Polymorphism Medicine & Life Sciences

DNA Copy Number Variations Medicine & Life Sciences

Genome Medicine & Life Sciences

Genes Chemical Compounds

Neoplasms Medicine & Life Sciences

Blood Platelets Medicine & Life Sciences

Microarrays Chemical Compounds

Genome-Wide Association Study Medicine & Life Sciences

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Research Output 1997 2017

44 Article

Evolution of neoantigen landscape during immune checkpoint blockade in non-small cell lung cancer

Anagnostou, V. , Smith, K. N. , Forde, P. M. , Niknafs, N. , Bhattacharya, R. , White, J. , Zhang, T. , Adleff, V. , Phallen, J. , Wali, N. , Hruban, C. , Guthrie, V. B. , Rodgers, K. , Naidoo, J. , Kang, H. , Sharfman, W. , Georgiades, C. , Verde, F. , Illei, P. , Li, Q. K. & 9 others Gabrielson, E., Brock, M. V., Zahnow, C. A., Baylin, S. B., Scharpf, R. B., Brahmer, J. R., Karchin, R., Pardoll, D. M. & Velculescu, V. E. Mar 1 2017 In : Cancer Discovery. 7, 3, p. 264-276 13 p.

Research output: Contribution to journal › Article

Non-Small Cell Lung Carcinoma

Neoplasms

T-Lymphocytes

Mutation

T-Cell Antigen Receptor

GATA3 frameshift mutation promotes tumor growth in human luminal breast cancer cells and induces transcriptional changes seen in primary GATA3 mutant breast cancers

Gustin, J. P., Miller, J., Farag, M., Marc Rosen, D., Thomas, M., Scharpf, R. B. & Lauring, J. Jan 1 2017 In : Oncotarget. 8, 61, p. 103415-103427 13 p.

Research output: Contribution to journal › Article

Frameshift Mutation

Breast Neoplasms

Mutation

Growth

Neoplasms

Genome-wide association of copy number polymorphisms and kidney function

Li, M., Carey, J., Cristiano, S., Susztak, K., Coresh, J., Boerwinkle, E., Kao, W. H. L., Beaty, T. H., Köttgen, A. & Scharpf, R. B. Jan 1 2017 In : PLoS ONE. 12, 1, e0170815

Research output: Contribution to journal › Article

DNA Copy Number Variations

glomerular filtration rate

renal function

Polymorphism

Glomerular Filtration Rate

The loss of GSTM1 associates with kidney failure and heart failure

Tin, A., Scharpf, R., Estrella, M. M., Yu, B., Grove, M. L., Chang, P. P., Matsushita, K., Köttgen, A., Arking, D. E., Boerwinkle, E., Le, T. H., Coresh, J. & Grams, M. E. Nov 1 2017 In : Journal of the American Society of Nephrology. 28, 11, p. 3345-3352 8 p.

Research output: Contribution to journal › Article

Glutathione Transferase

Renal Insufficiency

Heart Failure

Exome

Whole exome association of rare deletions in multiplex oral cleft families

Fu, J., Beaty, T. H., Scott, A. F., Hetmanski, J., Parker, M. M., Wilson, J. E. B., Marazita, M. L., Mangold, E., Albacha-Hejazi, H., Murray, J. C., Bureau, A., Carey, J., Cristiano, S., Ruczinski, I. & Scharpf, R. B. Jan 1 2017 In : Genetic Epidemiology. 41, 1, p. 61-69 9 p.

Research output: Contribution to journal › Article

Exome

Nucleotides

Genome

DNA