Robert A Casero

Professor

1980 …2020
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Research Output 1980 2020

2020

Pharmacological polyamine catabolism upregulation with methionine salvage pathway inhibition as an effective prostate cancer therapy

Affronti, H. C., Rowsam, A. M., Pellerite, A. J., Rosario, S. R., Long, M. D., Jacobi, J. J., Bianchi-Smiraglia, A., Boerlin, C. S., Gillard, B. M., Karasik, E., Foster, B. A., Moser, M., Wilton, J. H., Attwood, K., Nikiforov, M. A., Azabdaftari, G., Pili, R., Phillips, J. G., Casero, R. A. & Smiraglia, D. J., Dec 1 2020, In : Nature communications. 11, 1, 52.

Research output: Contribution to journalArticle

Open Access
catabolism
Salvaging
methionine
Polyamines
Methionine
2019

DFMO and 5-azacytidine increase M1 macrophages in the tumor microenvironment of murine ovarian cancer

Travers, M., Brown, S. M., Dunworth, M., Holbert, C. E., Wiehagen, K. R., Bachman, K. E., Foley, J. R., Stone, M. L., Baylin, S. B., Casero, R. A. & Zahnow, C., Jan 1 2019, In : Cancer Research. 79, 13, p. 3445-3454 10 p.

Research output: Contribution to journalArticle

Eflornithine
Azacitidine
Tumor Microenvironment
Ovarian Neoplasms
Macrophages

Dual inhibitors of LSD1 and spermine oxidase

Holshouser, S., Dunworth, M., Murray Stewart, T., Peterson, Y. K., Burger, P., Kirkpatrick, J., Chen, H. H., Casero, R. A. & Woster, P. M., Jan 1 2019, In : MedChemComm. 10, 5, p. 778-790 13 p.

Research output: Contribution to journalArticle

Tumors
Monoamine Oxidase
Histone Demethylases
Cells
Neoplasms

Elevation of cellular Mg2+ levels by the Mg2+ transporter, Alr1, supports growth of polyamine-deficient Saccharomyces cerevisiae cells

Hanner, A. S., Dunworth, M., Casero, R. A., MacDiarmid, C. W. & Park, M. H., Jan 1 2019, In : Journal of Biological Chemistry. 294, 45, p. 17131-17142 12 p.

Research output: Contribution to journalArticle

Polyamines
Yeast
Saccharomyces cerevisiae
Growth
Spermidine
2018

Corrigendum to “Structure–activity study for (bis)ureidopropyl- and (bis)thioureidopropyldiamine LSD1 inhibitors with 3-5-3 and 3-6-3 carbon backbone architectures” [Bioorg. Med. Chem. 23 (2015) 1601–1612]

Nowotarski, S. L., Pachaiyappan, B., Holshouser, S. L., Kutz, C. J., Li, Y., Huang, Y., Sharma, S. K., Casero, R. A. & Woster, P. M., Jan 1 2018, (Accepted/In press) In : Bioorganic and Medicinal Chemistry.

Research output: Contribution to journalArticle

Lysine
Carbon
Horseradish Peroxidase
Manuscripts
Peptides

Coupling of the polyamine and iron metabolism pathways in the regulation of proliferation: Mechanistic links to alterations in key polyamine biosynthetic and catabolic enzymes

Lane, D. J. R., Bae, D. H., Siafakas, A. R., Suryo Rahmanto, Y., Al-Akra, L., Jansson, P. J., Casero, R. A. & Richardson, D. R., Jan 1 2018, (Accepted/In press) In : Biochimica et Biophysica Acta - Molecular Basis of Disease.

Research output: Contribution to journalArticle

Polyamines
Iron
Enzymes
Spermine
Spermidine

Curcumin mediates polyamine metabolism and sensitizes gastrointestinal cancer cells to antitumor polyamine-targeted therapies

Murray Stewart, T., Dunworth, M., Lui, Y., Giardiello, F. M., Woster, P. M. & Casero, R. A., Aug 1 2018, In : PLoS One. 13, 8, e0202677.

Research output: Contribution to journalArticle

Curcumin
Gastrointestinal Neoplasms
curcumin
Polyamines
polyamines

Distinct immunomodulatory effects of spermine oxidase in colitis induced by epithelial injury or infection

Gobert, A. P., Al-Greene, N. T., Singh, K., Coburn, L. A., Sierra, J. C., Verriere, T. G., Luis, P. B., Schneider, C., Asim, M., Allaman, M. M., Barry, D. P., Cleveland, J. L., Shields, C. E. D., Casero, R. A., Washington, M. K., Piazuelo, M. B. & Wilson, K. T., Jun 5 2018, In : Frontiers in Immunology. 9, JUN, 1242.

Research output: Contribution to journalArticle

Colitis
Spermidine
Citrobacter rodentium
Dextran Sulfate
Polyamines

Efficacy and Safety of Curcumin in Treatment of Intestinal Adenomas in Patients With Familial Adenomatous Polyposis

Cruz-Correa, M., Hylind, L. M., Marrero, J. H., Zahurak, M. L., Murray Stewart, T., Casero, R. A., Montgomery, E. A., Iacobuzio-Donahue, C., Brosens, L. A., Offerhaus, G. J., Umar, A., Rodriguez, L. M. & Giardiello, F. M., Sep 1 2018, In : Gastroenterology. 155, 3, p. 668-673 6 p.

Research output: Contribution to journalArticle

Adenomatous Polyposis Coli
Curcumin
Adenoma
Safety
Polyps

Metabolomic studies identify changes in transmethylation and polyamine metabolism in a brain-specific mouse model of tuberous sclerosis complex

McKenna, J., Kapfhamer, D., Kinchen, J. M., Wasek, B., Dunworth, M., Murray Stewart, T., Bottiglieri, T., Casero, R. A. & Gambello, M. J., Jun 15 2018, In : Human Molecular Genetics. 27, 12, p. 2113-2124 12 p.

Research output: Contribution to journalArticle

Tuberous Sclerosis
Metabolomics
Polyamines
Methylation
Putrescine

N1-Nonyl-1,4-diaminobutane ameliorates brain infarction size in photochemically induced thrombosis model mice

Masuko, T., Takao, K., Samejima, K., Shirahata, A., Igarashi, K., Casero, R. A., Kizawa, Y. & Sugita, Y., Apr 13 2018, In : Neuroscience Letters. 672, p. 118-122 5 p.

Research output: Contribution to journalArticle

Brain Infarction
Putrescine
Thrombosis
Polyamines
Enzyme Inhibitors

Placental polyamine metabolism differs by fetal sex, fetal growth restriction, and preeclampsia

Gong, S., Sovio, U., Aye, I. L., Gaccioli, F., Dopierala, J., Johnson, M. D., Wood, A. M., Cook, E., Jenkins, B. J., Koulman, A., Casero, R. A., Constância, M., Charnock-Jones, D. S. & Smith, G. C., Jul 12 2018, In : JCI insight. 3, 13

Research output: Contribution to journalArticle

Open Access
Polyamines
Fetal Development
Pre-Eclampsia
Placenta
Spermine Synthase

Polyamine catabolism and oxidative damage

Murray Stewart, T., Dunston, T. T., Woster, P. M. & Casero, R. A., Jan 1 2018, In : Journal of Biological Chemistry. 293, 48, p. 18736-18745 10 p.

Research output: Contribution to journalReview article

Polyamines
Yeast
Amines
Homeostasis
Maintenance

Polyamine metabolism and cancer: treatments, challenges and opportunities

Casero, R. A., Murray Stewart, T. & Pegg, A. E., Jan 1 2018, (Accepted/In press) In : Nature Reviews Cancer.

Research output: Contribution to journalArticle

Polyamines
Neoplasms
Therapeutics
Carcinogenesis
Clinical Trials

Polymeric Prodrugs Targeting Polyamine Metabolism Inhibit Zika Virus Replication

Routhu, N. K., Xie, Y., Dunworth, M., Casero, R. A., Oupicky, D. & Byrareddy, S. N., Jan 27 2018, (Accepted/In press) In : Molecular Pharmaceutics.

Research output: Contribution to journalArticle

Prodrugs
Polyamines
Virus Replication
Chikungunya virus
Cell Line

Reduction in polyamine catabolism leads to spermine-mediated airway epithelial injury and induces asthma features

Jain, V., Raina, S., Gheware, A. P., Singh, R., Rehman, R., Negi, V., Murray Stewart, T., Mabalirajan, U., Mishra, A. K., Casero, R. A., Agrawal, A. & Ghosh, B., Oct 1 2018, In : Allergy: European Journal of Allergy and Clinical Immunology. 73, 10, p. 2033-2045 13 p.

Research output: Contribution to journalArticle

Spermine
Polyamines
Asthma
Epithelial Cells
Apoptosis

Targeting the aryl hydrocarbon receptor/polyamine biosynthesis axis of evil for cancer therapy

Casero, R. A., Oct 1 2018, In : Journal of Clinical Investigation. 128, 10, p. 4254-4256 3 p.

Research output: Contribution to journalReview article

Aryl Hydrocarbon Receptors
Polyamines
Neoplasms
Therapeutics
Growth
2017

Activation of endoplasmic reticulum stress response by enhanced polyamine catabolism is important in the mediation of cisplatin-induced acute kidney injury

Zahedi, K., Barone, S., Destefano-Shields, C., Brooks, M., Murray Stewart, T., Dunworth, M., Li, W., Doherty, J. R., Hall, M. A., Smith, R. D., Cleveland, J. L., Casero, R. A. & Soleimani, M., Sep 1 2017, In : PLoS One. 12, 9, e0184570.

Research output: Contribution to journalArticle

cisplatin
Endoplasmic Reticulum Stress
Polyamines
polyamines
Acute Kidney Injury

Biochemical evaluation of the anticancer potential of the polyamine-based nanocarrier Nano 11047

Murray Stewart, T., Ferrari, E., Xie, Y., Yu, F., Marton, L. J., Oupicky, D. & Casero, R. A., Apr 1 2017, In : PLoS One. 12, 4, e0175917.

Research output: Contribution to journalArticle

Polyamines
polyamines
Metabolism
Tumors
metabolism

Correction: Biochemical evaluation of the anticancer potential of the polyamine-based nanocarrier Nano11047 (PLoS ONE (2017) 12:4 (e0175917) DOI: 10.1371/journal.pone.0175917)

Murray-Stewart, T., Ferrari, E., Xie, Y., Yu, F., Marton, L. J., Oupicky, D. & Casero, R. A., May 1 2017, In : PLoS One. 12, 5, e0178102.

Research output: Contribution to journalComment/debate

Polyamines
polyamines
Isomers
Molecules
4-iodo-2,5-dimethoxyphenylisopropylamine

Elucidating the Structure of N1-Acetylisoputreanine: A Novel Polyamine Catabolite in Human Urine

Fitzgerald, B. L., Mahapatra, S., Farmer, D. K., McNeil, M. R., Casero, R. A. & Belisle, J. T., Jul 31 2017, In : ACS Omega. 2, 7, p. 3921-3930 10 p.

Research output: Contribution to journalArticle

Polyamines
Metabolites
Lactams
Liquid chromatography
Biomarkers

Self-immolative nanoparticles for simultaneous delivery of microRNA and targeting of polyamine metabolism in combination cancer therapy

Xie, Y., Murray Stewart, T., Wang, Y., Yu, F., Li, J., Marton, L. J., Casero, R. A. & Oupický, D., Jan 28 2017, In : Journal of Controlled Release. 246, p. 110-119 10 p.

Research output: Contribution to journalArticle

Polyamines
MicroRNAs
Nanoparticles
Neoplasms
Antineoplastic Combined Chemotherapy Protocols

Targeting hexokinase 2 inhibition promotes radiosensitization in HPV16 E7-induced cervical cancer and suppresses tumor growth

Liu, Y., Murray Stewart, T., Casero, R. A., Kagiampakis, I., Jin, L., Jiawen, Z., Huihui, W., Che, Q., Huan, T., Ke, J., Feizhou, J., Fangyuan, W. & Wan, X., Jun 1 2017, In : International Journal of Oncology. 50, 6, p. 2011-2023 13 p.

Research output: Contribution to journalArticle

Hexokinase
Uterine Cervical Neoplasms
Glycolysis
Growth
Neoplasms
2016

Arginase 2 deletion leads to enhanced M1 macrophage activation and upregulated polyamine metabolism in response to Helicobacter pylori infection

Hardbower, D. M., Asim, M., Murray Stewart, T., Casero, R. A., Verriere, T., Lewis, N. D., Chaturvedi, R., Piazuelo, M. B. & Wilson, K. T., Apr 13 2016, (Accepted/In press) In : Amino Acids. p. 1-14 14 p.

Research output: Contribution to journalArticle

Arginase
Macrophage Activation
Macrophages
Polyamines
Helicobacter Infections

Decrease in acrolein toxicity based on the decline of polyamine oxidases

Uemura, T., Nakamura, M., Sakamoto, A., Suzuki, T., Dohmae, N., Terui, Y., Tomitori, H., Casero, R. A., Kashiwagi, K. & Igarashi, K., Oct 1 2016, In : International Journal of Biochemistry and Cell Biology. 79, p. 151-157 7 p.

Research output: Contribution to journalArticle

Acrolein
Toxicity
Oxidoreductases
Cells
Transfection

Epigenetic silencing of miR-124 prevents spermine oxidase regulation: implications for Helicobacter pylori-induced gastric cancer

Murray Stewart, T., Sierra, J. C., Piazuelo, M. B., Mera, R. M., Chaturvedi, R., Bravo, L. E., Correa, P., Schneider, B. G., Wilson, K. T. & Casero, R. A., Apr 4 2016, (Accepted/In press) In : Oncogene.

Research output: Contribution to journalArticle

Epigenomics
Helicobacter pylori
Stomach Neoplasms
Gastritis
DNA Damage
DNA Methylation
Epigenomics
Histones
Co-Repressor Proteins
Neoplasms

Largazole Analogues Embodying Radical Changes in the Depsipeptide Ring: Development of a More Selective and Highly Potent Analogue

Almaliti, J., Al-Hamashi, A. A., Negmeldin, A. T., Hanigan, C. L., Perera, L., Pflum, M. K. H., Casero, R. A. & Tillekeratne, L. M. V., Dec 8 2016, In : Journal of Medicinal Chemistry. 59, 23, p. 10642-10660 19 p.

Research output: Contribution to journalArticle

Depsipeptides
Thiazoles
Histone Deacetylase Inhibitors
Histone Deacetylases
largazole

MOF Acetylates the Histone Demethylase LSD1 to Suppress Epithelial-to-Mesenchymal Transition

Luo, H., Shenoy, A. K., Li, X., Jin, Y., Jin, L., Cai, Q., Tang, M., Liu, Y., Chen, H., Reisman, D., Wu, L., Seto, E., Qiu, Y., Dou, Y., Casero, R. A. & Lu, J., Jun 21 2016, In : Cell Reports. 15, 12, p. 2665-2678 14 p.

Research output: Contribution to journalArticle

Histone Demethylases
Epithelial-Mesenchymal Transition
Tumors
Acetylation
Histones

Reduction of Murine Colon Tumorigenesis Driven by Enterotoxigenic Bacteroides fragilis Using Cefoxitin Treatment

Destefano Shields, C. E., Van Meerbeke, S. W., Housseau, F., Wang, H., Huso, D. L., Casero, R. A., O'Hagan, H. M. & Sears, C. L., Jul 1 2016, In : Journal of Infectious Diseases. 214, 1, p. 122-129 8 p.

Research output: Contribution to journalArticle

Cefoxitin
Bacteroides fragilis
Colon
Carcinogenesis
Interleukin-17

Targeting polyamine metabolism for cancer therapy and prevention

Tracy, R. M. S., Woster, P. M. & Casero, R. A., 2016, In : Biochemical Journal. 473, 19, p. 2937-2953 17 p.

Research output: Contribution to journalReview article

Polyamines
Metabolism
Chemotherapy
Neoplasms
Drug Therapy
2015

Increased Helicobacter pylori-associated gastric cancer risk in the Andean region of Colombia is mediated by spermine oxidase

Chaturvedi, R., De Sablet, T., Asim, M., Piazuelo, M. B., Barry, D. P., Verriere, T. G., Sierra, J. C., Hardbower, D. M., Delgado, A. G., Schneider, B. G., Israel, D. A., Romero-Gallo, J., Nagy, T. A., Morgan, D. R., Murray Stewart, T., Bravo, L. E., Peek, R. M., Fox, J. G., Woster, P. M., Casero, R. A. & 2 others, Correa, P. & Wilson, K. T., Jun 27 2015, In : Oncogene. 34, 26, p. 3429-3440 12 p.

Research output: Contribution to journalArticle

Colombia
Helicobacter pylori
Stomach Neoplasms
DNA Damage
Stomach

Mammalian polyamine catabolism

Murray Stewart, T. & Casero, R. A., Jan 1 2015, Polyamines: A Universal Molecular Nexus for Growth, Survival, and Specialized Metabolism. Springer Japan, p. 61-76 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Polyamines
Spermidine
Oxidation
Spermine
Poisons

Metabolism links bacterial biofilms and colon carcinogenesis

Johnson, C. H., Dejea, C. M., Edler, D., Hoang, L. T., Santidrian, A. F., Felding, B. H., Ivanisevic, J., Cho, K., Wick, E. C., Hechenbleikner, E. M., Uritboonthai, W., Goetz, L., Casero, R. A., Pardoll, A. M., White, J. R., Patti, G. J., Sears, C. L. & Siuzdak, G., Jun 2 2015, In : Cell Metabolism. 21, 6, p. 891-897 7 p.

Research output: Contribution to journalArticle

Biofilms
Colon
Carcinogenesis
Colonic Neoplasms
Neoplasms

Structure-activity study for (bis)ureidopropyl- and (bis)thioureidopropyldiamine LSD1 inhibitors with 3-5-3 and 3-6-3 carbon backbone architectures

Nowotarski, S. L., Pachaiyappan, B., Holshouser, S. L., Kutz, C. J., Li, Y., Huang, Y., Sharma, S. K., Casero, R. A. & Woster, P. M., Apr 1 2015, In : Bioorganic and Medicinal Chemistry. 23, 7, p. 1601-1612 12 p.

Research output: Contribution to journalArticle

Lysine
Carbon
Tumors
Tumor Suppressor Genes
Thiourea
2014

Activation of EGFR and ERBB2 by helicobacter pylori results in survival of gastric epithelial cells with DNA damage

Chaturvedi, R., Asim, M., Piazuelo, M. B., Yan, F., Barry, D. P., Sierra, J. C., Delgado, A. G., Hill, S., Casero, R. A., Bravo, L. E., Dominguez, R. L., Correa, P., Polk, D. B., Washington, M. K., Rose, K. L., Schey, K. L., Morgan, D. R., Peek, R. M. & Wilson, K. T., 2014, In : Gastroenterology. 146, 7

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Helicobacter pylori
DNA Damage
Stomach
Epithelial Cells

A selective phenelzine analogue inhibitor of histone demethylase LSD1

Prusevich, P., Kalin, J. H., Ming, S. A., Basso, M., Givens, J., Li, X., Hu, J., Taylor, M. S., Cieniewicz, A. M., Hsiao, P. Y., Huang, R., Roberson, H., Adejola, N., Avery, L. B., Casero, R. A., Taverna, S. D., Qian, J., Tackett, A. J., Ratan, R. R., McDonald, O. G. & 2 others, Feinberg, A. P. & Cole, P. A., Jun 20 2014, In : ACS Chemical Biology. 9, 6, p. 1284-1293 10 p.

Research output: Contribution to journalArticle

Histone Demethylases
Phenelzine
Lysine
Monoamine Oxidase
Methylation

Polyamine catabolism in carcinogenesis: Potential targets for chemotherapy and chemoprevention

Battaglia, V., DeStefano Shields, C., Murray Stewart, T. & Casero, R. A., 2014, In : Amino Acids. 46, 3, p. 511-519 9 p.

Research output: Contribution to journalArticle

Chemotherapy
Chemoprevention
Polyamines
Spermidine
Spermine

Proximal tubule epithelial cell specific ablation of the spermidine/spermine N1-acetyltransferase gene reduces the severity of renal ischemia/reperfusion injury

Zahedi, K., Barone, S., Wang, Y., Murray Stewart, T., Roy-Chaudhury, P., Smith, R. D., Casero, R. A. & Soleimani, M., Nov 12 2014, In : PLoS One. 9, 11, e110161.

Research output: Contribution to journalArticle

proximal tubules
acetyltransferases
Acetyltransferases
Spermidine
Spermine

Spermine oxidase is a regulator of macrophage host response to Helicobacter pylori: Enhancement of antimicrobial nitric oxide generation by depletion of spermine

Chaturvedi, R., Asim, M., Barry, D. P., Frye, J. W., Casero, R. A. & Wilson, K. T., 2014, In : Amino Acids. 46, 3, p. 531-542 12 p.

Research output: Contribution to journalArticle

Spermine
Macrophages
Helicobacter pylori
Nitric Oxide
Nitric Oxide Synthase

Synthesis and biological evaluation of largazole analogues with modified surface recognition cap groups

Bhansali, P., Hanigan, C. L., Perera, L., Casero, R. A. & Tillekeratne, L. M. V., Oct 30 2014, In : European Journal of Medicinal Chemistry. 86, p. 528-541 14 p.

Research output: Contribution to journalArticle

Acetylation
Histones
Histone Deacetylase Inhibitors
Colorectal Neoplasms
Growth
Polyamines
Myeloid Cells
Cadherins
Acute Myeloid Leukemia
Histones
2013

Histone deacetylase inhibition overcomes drug resistance through a miRNA-dependent mechanism

Murray Stewart, T., Hanigan, C. L., Woster, P. M., Marton, L. J. & Casero, R. A., Oct 2013, In : Molecular Cancer Therapeutics. 12, 10, p. 2088-2099 12 p.

Research output: Contribution to journalArticle

Histone Deacetylases
Polyamines
MicroRNAs
Drug Resistance
Spermine

Loss of LSD1 (lysine-specific demethylase 1) suppresses growth and alters gene expression of human colon cancer cells in a p53- and DNMT1 (DNA methyltransferase 1)-independent manner

Jin, L., Hanigan, C. L., Wu, Y., Wang, W., Park, B. H., Woster, P. M. & Casero, R. A., Jan 15 2013, In : Biochemical Journal. 449, 2, p. 459-468 10 p.

Research output: Contribution to journalArticle

Methyltransferases
Gene expression
Colonic Neoplasms
Lysine
Cells

Pentamines as substrate for human spermine oxidase

Takao, K., Shirahata, A., Samejima, K., Casero, R. A., Igarashi, K. & Sugita, Y., Mar 2013, In : Biological and Pharmaceutical Bulletin. 36, 3, p. 407-411 5 p.

Research output: Contribution to journalArticle

pentamine
Spermine
tetramethylenedisulfotetramine
Polyamines
Nitrogen

Polyamines and cancer: implications for chemotherapy and chemoprevention.

Nowotarski, S. L., Woster, P. M. & Casero, R. A., 2013, In : Expert Reviews in Molecular Medicine. 15

Research output: Contribution to journalArticle

Chemoprevention
Polyamines
Drug Therapy
Neoplasms
Clinical Trials
Eflornithine
Chemoprevention
Polyamines
Thymidine
Colonic Neoplasms
2012

Hepatocyte-specific ablation of spermine/spermidine-N1-acetyltransferase gene reduces the severity of CCL4-induced acute liver injury

Zahedi, K., Barone, S. L., Xu, J., Steinberg, N., Schuster, R., Lentsch, A. B., Amlal, H., Wang, J., Casero, R. A. & Soleimani, M., Sep 1 2012, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 303, 5

Research output: Contribution to journalArticle

Spermine
Hepatocytes
Liver
Wounds and Injuries
Genes

Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia

Schenk, T., Chen, W. C., Göllner, S., Howell, L., Jin, L., Hebestreit, K., Klein, H. U., Popescu, A. C., Burnett, A., Mills, K., Casero, R. A., Marton, L., Woster, P., Minden, M. D., Dugas, M., Wang, J. C. Y., Dick, J. E., Müller-Tidow, C., Petrie, K. & Zelent, A., Apr 2012, In : Nature Medicine. 18, 4, p. 605-611 7 p.

Research output: Contribution to journalArticle

Tretinoin
Acute Myeloid Leukemia
Tranylcypromine
Myeloid Cells
Therapeutics

Knockdown of ornithine decarboxylase antizyme 1 causes loss of uptake regulation leading to increased N 1, N 11-bis(ethyl) norspermine (BENSpm) accumulation and toxicity in NCI H157 lung cancer cells

Fraser, A. V., Goodwin, A. C., Hacker-Prietz, A., Sugar, E., Woster, P. M. & Casero, R. A., Feb 2012, In : Amino Acids. 42, 2-3, p. 529-538 10 p.

Research output: Contribution to journalArticle

Polyamines
Toxicity
Lung Neoplasms
Cells
Ornithine Decarboxylase