Robert A Casero

Professor

1980 …2018
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Polyamines Medicine & Life Sciences
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Eflornithine Medicine & Life Sciences

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Research Output 1980 2018

Corrigendum to “Structure–activity study for (bis)ureidopropyl- and (bis)thioureidopropyldiamine LSD1 inhibitors with 3-5-3 and 3-6-3 carbon backbone architectures” [Bioorg. Med. Chem. 23 (2015) 1601–1612]

Nowotarski, S. L., Pachaiyappan, B., Holshouser, S. L., Kutz, C. J., Li, Y., Huang, Y., Sharma, S. K., Casero, R. A. & Woster, P. M., Jan 1 2018, (Accepted/In press) In : Bioorganic and Medicinal Chemistry.

Research output: Contribution to journalArticle

Rotary engines
Nitrobenzene
Lysine
Carbon
Unsaturated polymers

Coupling of the polyamine and iron metabolism pathways in the regulation of proliferation: Mechanistic links to alterations in key polyamine biosynthetic and catabolic enzymes

Lane, D. J. R., Bae, D. H., Siafakas, A. R., Suryo Rahmanto, Y., Al-Akra, L., Jansson, P. J., Casero, R. A. & Richardson, D. R., Jan 1 2018, (Accepted/In press) In : Biochimica et Biophysica Acta - Molecular Basis of Disease.

Research output: Contribution to journalArticle

Polyamines
Iron
Enzymes
Spermine
Spermidine

Curcumin mediates polyamine metabolism and sensitizes gastrointestinal cancer cells to antitumor polyamine-targeted therapies

Murray-Stewart, T., Dunworth, M., Lui, Y., Giardiello, F. M., Woster, P. M. & Casero, R. A., Aug 1 2018, In : PloS one. 13, 8, e0202677

Research output: Contribution to journalArticle

Curcumin
Gastrointestinal Neoplasms
curcumin
Polyamines
polyamines

Distinct immunomodulatory effects of spermine oxidase in colitis induced by epithelial injury or infection

Gobert, A. P., Al-Greene, N. T., Singh, K., Coburn, L. A., Sierra, J. C., Verriere, T. G., Luis, P. B., Schneider, C., Asim, M., Allaman, M. M., Barry, D. P., Cleveland, J. L., Shields, C. E. D., Casero, R. A., Washington, M. K., Piazuelo, M. B. & Wilson, K. T., Jun 5 2018, In : Frontiers in Immunology. 9, JUN, 1242

Research output: Contribution to journalArticle

Colitis
Spermidine
Citrobacter rodentium
Dextran Sulfate
Polyamines

Efficacy and Safety of Curcumin in Treatment of Intestinal Adenomas in Patients With Familial Adenomatous Polyposis

Cruz-Correa, M., Hylind, L. M., Marrero, J. H., Zahurak, M. L., Murray-Stewart, T., Casero, R. A., Montgomery, E. A., Iacobuzio-Donahue, C., Brosens, L. A., Offerhaus, G. J., Umar, A., Rodriguez, L. M. & Giardiello, F. M., Sep 1 2018, In : Gastroenterology. 155, 3, p. 668-673 6 p.

Research output: Contribution to journalArticle

Adenomatous Polyposis Coli
Curcumin
Adenoma
Safety
Polyps