Robert A Casero

Professor

1980 …2019
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Fingerprint Dive into the research topics where Robert A Casero is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 2 Similar Profiles
Polyamines Medicine & Life Sciences
Spermine Medicine & Life Sciences
Spermidine Chemical Compounds
Acetyltransferases Chemical Compounds
Cells Chemical Compounds
Ornithine Decarboxylase Medicine & Life Sciences
Eflornithine Medicine & Life Sciences
Growth Medicine & Life Sciences

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Research Output 1980 2019

DFMO and 5-azacytidine increase M1 macrophages in the tumor microenvironment of murine ovarian cancer

Travers, M., Brown, S. M., Dunworth, M., Holbert, C. E., Wiehagen, K. R., Bachman, K. E., Foley, J. R., Stone, M. L., Baylin, S. B., Casero, R. A. & Zahnow, C., Jan 1 2019, In : Cancer Research. 79, 13, p. 3445-3454 10 p.

Research output: Contribution to journalArticle

Eflornithine
Azacitidine
Tumor Microenvironment
Ovarian Neoplasms
Macrophages

Dual inhibitors of LSD1 and spermine oxidase

Holshouser, S., Dunworth, M., Murray Stewart, T., Peterson, Y. K., Burger, P., Kirkpatrick, J., Chen, H. H., Casero, R. A. & Woster, P. M., Jan 1 2019, In : MedChemComm. 10, 5, p. 778-790 13 p.

Research output: Contribution to journalArticle

Tumors
Monoamine Oxidase
Histone Demethylases
Cells
Neoplasms

Elevation of cellular Mg2+ levels by the Mg2+ transporter, Alr1, supports growth of polyamine-deficient Saccharomyces cerevisiae cells

Hanner, A. S., Dunworth, M., Casero, R. A., MacDiarmid, C. W. & Park, M. H., Jan 1 2019, In : Journal of Biological Chemistry. 294, 45, p. 17131-17142 12 p.

Research output: Contribution to journalArticle

Polyamines
Yeast
Saccharomyces cerevisiae
Growth
Spermidine

Corrigendum to “Structure–activity study for (bis)ureidopropyl- and (bis)thioureidopropyldiamine LSD1 inhibitors with 3-5-3 and 3-6-3 carbon backbone architectures” [Bioorg. Med. Chem. 23 (2015) 1601–1612]

Nowotarski, S. L., Pachaiyappan, B., Holshouser, S. L., Kutz, C. J., Li, Y., Huang, Y., Sharma, S. K., Casero, R. A. & Woster, P. M., Jan 1 2018, (Accepted/In press) In : Bioorganic and Medicinal Chemistry.

Research output: Contribution to journalArticle

Lysine
Carbon
Horseradish Peroxidase
Manuscripts
Peptides

Coupling of the polyamine and iron metabolism pathways in the regulation of proliferation: Mechanistic links to alterations in key polyamine biosynthetic and catabolic enzymes

Lane, D. J. R., Bae, D. H., Siafakas, A. R., Suryo Rahmanto, Y., Al-Akra, L., Jansson, P. J., Casero, R. A. & Richardson, D. R., Jan 1 2018, (Accepted/In press) In : Biochimica et Biophysica Acta - Molecular Basis of Disease.

Research output: Contribution to journalArticle

Polyamines
Iron
Enzymes
Spermine
Spermidine