Richard Leigh

Assistant Professor

20102020

Research output per year

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Research Output

2020
2019

Molecular signature of penumbra in acute ischemic stroke: a pilot transcriptomics study

Nadareishvili, Z., Kelley, D., Luby, M., Simpkins, A. N., Leigh, R., Lynch, J. K., Hsia, A. W., Benson, R. T., Johnson, K. R., Hallenbeck, J. M. & Latour, L. L., Apr 1 2019, In : Annals of Clinical and Translational Neurology. 6, 4, p. 817-820 4 p.

Research output: Contribution to journalArticle

Open Access

MRI-based thrombolytic therapy in patients with acute ischemic stroke presenting with a low NIHSS

Majidi, S., Luby, M., Lynch, J. K., Hsia, A. W., Benson, R. T., Kalaria, C. P., Nadareishvili, Z., Latour, L. L. & Leigh, R., Oct 15 2019, In : Neurology. 93, 16, p. e1507-e1513

Research output: Contribution to journalArticle

Neuroimaging of cerebral small vessel disease and age-related cognitive changes

Caunca, M. R., De Leon-Benedetti, A., Latour, L., Leigh, R. & Wright, C. B., Jan 1 2019, In : Frontiers in Aging Neuroscience. 11, JUN, 145.

Research output: Contribution to journalReview article

Open Access

New concept in stroke diagnosis

Ali, E. D., Leigh, R. & Kassab, G. S., Jan 1 2019, In : MCB Molecular and Cellular Biomechanics. 16, 4, p. 225-233 9 p.

Research output: Contribution to journalArticle

Open Access

Post-Stroke Blood-Brain Barrier Disruption and Poor Functional Outcome in Patients Receiving Thrombolytic Therapy

Nadareishvili, Z., Simpkins, A. N., Hitomi, E., Reyes, D. & Leigh, R., Jan 1 2019, In : Cerebrovascular Diseases.

Research output: Contribution to journalArticle

Rapid Apparent Diffusion Coefficient Evolution After Early Revascularization

Hsia, A. W., Luby, M., Cullison, K., Burton, S., Armonda, R., Liu, A. H., Leigh, R., Nadareishvili, Z., Benson, R. T., Lynch, J. K. & Latour, L. L., Aug 1 2019, In : Stroke. 50, 8, p. 2086-2092 7 p.

Research output: Contribution to journalArticle

The Efficacy of IV Tissue Plasminogen Activator for Restoring Cerebral Blood Flow in the Hours Immediately after Administration in Patients with Acute Stroke

on behalf of the NIH Natural History of Stroke Investigators, Mar 1 2019, In : Journal of Neuroimaging. 29, 2, p. 206-210 5 p.

Research output: Contribution to journalArticle

2018

An MRI Hyperintense Acute Reperfusion Marker Is Related to Elevated Peripheral Monocyte Count in Acute Ischemic Stroke

Nadareishvili, Z., Luby, M., Leigh, R., Shah, J., Lynch, J. K., Hsia, A. W., Benson, R. T. & Latour, L. L., Jan 1 2018, In : Journal of Neuroimaging. 28, 1, p. 57-60 4 p.

Research output: Contribution to journalArticle

Blood-ocular barrier disruption in patients with acute stroke

Hitomi, E., Simpkins, A. N., Luby, M., Latour, L. L., John Leigh, R. & Leigh, R., Mar 13 2018, In : Neurology. 90, 11, p. e915-e923

Research output: Contribution to journalArticle

Recurrent thrombolysis of a stuttering lacunar infarction captured on serial MRIs

Naqvi, I., Simpkins, A. N., Cullison, K., Elliott, E., Reyes, D., Leigh, R. & Lynch, J. K., Dec 2018, In : eNeurologicalSci. 13, p. 14-17 4 p.

Research output: Contribution to journalArticle

Open Access

White Matter Hyperintensity-Associated Blood-Brain Barrier Disruption and Vascular Risk Factors

NIH Natural History of Stroke Investigators, Feb 2018, In : Journal of Stroke and Cerebrovascular Diseases. 27, 2, p. 466-471 6 p.

Research output: Contribution to journalArticle

2017

Blood-brain barrier leakage increases with small vessel disease in acute ischemic stroke

On behalf of the STIR/VISTA Imaging Collaboration, Jan 1 2017, In : Neurology. 89, 21, p. 2143-2150 8 p.

Research output: Contribution to journalArticle

Early change in stroke size performs best in predicting response to therapy

Simpkins, A. N., Dias, C., Norato, G., Kim, E. & Leigh, R., Oct 1 2017, In : Cerebrovascular Diseases. 44, 3-4, p. 141-149 9 p.

Research output: Contribution to journalArticle

Perfusion Deficits and Association with Clinical Outcome in Patients with Anterior Choroidal Artery Stroke

Alqahtani, S. A., Luby, M., Nadareishvili, Z., Benson, R. T., Hsia, A. W., Leigh, R. & Lynch, J. K., Aug 1 2017, In : Journal of Stroke and Cerebrovascular Diseases. 26, 8, p. 1755-1759 5 p.

Research output: Contribution to journalArticle

Recovery of orthographic processing after stroke: A longitudinal fMRI study

Purcell, J., Sebastian, R., Leigh, R., Jarso, S., Davis, C., Posner, J., Wright, A. & Hillis, A. E., Jul 1 2017, In : Cortex. 92, p. 103-118 16 p.

Research output: Contribution to journalArticle

2016

Imaging active intracerebral hemorrhage after attempted endovascular thrombectomy

Alqahtani, S. A. & Leigh, R., Jun 1 2016, In : JAMA Neurology. 73, 6, p. 754 1 p.

Research output: Contribution to journalComment/debate

Patterns and Implications of Intracranial Arterial Remodeling in Stroke Patients

Qiao, Y., Anwar, Z., Intrapiromkul, J., Liu, L., Zeiler, S. R., Leigh, R., Zhang, Y., Guallar, E. & Wasserman, B. A., Feb 1 2016, In : Stroke. 47, 2, p. 434-440 7 p.

Research output: Contribution to journalArticle

2015

Diagnostic quality and accuracy of low dose 3D-DSA protocols in the evaluation of intracranial aneurysms

Pearl, M. S., Torok, C., Katz, Z., Messina, S. A., Blasco, J., Tamargo, R. J., Huang, J., Leigh, R., Zeiler, S., Radvany, M., Ehtiati, T. & Gailloud, P., May 1 2015, In : Journal of NeuroInterventional Surgery. 7, 5, p. 386-390 5 p.

Research output: Contribution to journalArticle

Diffusion-perfusion mismatch: An opportunity for improvement in cortical function

Motta, M., Ramadan, A., Hillis, A. E., Gottesman, R. F. & Leigh, R., 2015, In : Frontiers in Neurology. 6, JAN, 280.

Research output: Contribution to journalArticle

Simultaneous detection and separation of hyperacute intracerebral hemorrhage and cerebral ischemia using amide proton transfer MRI

Wang, M., Hong, X., Chang, C. F., Li, Q., Ma, B., Zhang, H., Xiang, S., Heo, H. Y., Zhang, Y., Lee, D. H., Jiang, S., Leigh, R., Koehler, R. C., Van Zijl, P. C. M., Wang, J. & Zhou, J., Jul 1 2015, In : Magnetic Resonance in Medicine. 74, 1, p. 42-50 9 p.

Research output: Contribution to journalArticle

2014

Intracranial plaque enhancement in patients with cerebrovascular events on high-spatial-resolution MR images

Qiao, Y., Zeiler, S. R., Mirbagheri, S., Leigh, R., Urrutia, V., Wityk, R. & Wasserman, B. A., 2014, In : Radiology. 271, 2, p. 534-542 9 p.

Research output: Contribution to journalArticle

MRI-guided selection of patients for treatment of acute ischemic stroke

Leigh, R. & Krakauer, J. W., 2014, In : Current Opinion in Neurology. 27, 4, p. 425-433 9 p.

Research output: Contribution to journalArticle

Pediatric hemiplegic migraine: Role of multiple MRI techniques in evaluation of reversible hypoperfusion

Bosemani, T., Burton, V. J., Felling, R. J., Leigh, R., Oakley, C., Poretti, A. & Huisman, T. A., 2014, In : Cephalalgia. 34, 4, p. 311-315 5 p.

Research output: Contribution to journalArticle

The roles of occipitotemporal cortex in reading, spelling, and naming

Sebastian, R., Gomez, Y., Leigh, R., Davis, C., Newhart, M. & Hillis, A. E., 2014, In : Cognitive Neuropsychology. 31, 5-6, p. 511-528 18 p.

Research output: Contribution to journalArticle

2013

6p25 microdeletion: White matter abnormalities in an adult patient

Vernon, H. J., Bytyci Telegrafi, A., Batista, D., Owegi, M. & Leigh, R., Jul 2013, In : American Journal of Medical Genetics, Part A. 161, 7, p. 1686-1689 4 p.

Research output: Contribution to journalArticle

Acute stroke imaging research roadmap II

Wintermark, M., Albers, G. W., Broderick, J. P., Demchuk, A. M., Fiebach, J. B., Fiehler, J., Grotta, J. C., Houser, G., Jovin, T. G., Lees, K. R., Lev, M. H., Liebeskind, D. S., Luby, M., Muir, K. W., Parsons, M. W., Von Kummer, R., Wardlaw, J. M., Wu, O., Yoo, A. J., Alexandrov, A. V. & 47 others, Alger, J. R., Aviv, R. I., Bammer, R., Baron, J. C., Calamante, F., Campbell, B. C. V., Carpenter, T. C., Christensen, S., Copen, W. A., Derdeyn, C. P., Haley, E. C., Khatri, P., Kudo, K., Lansberg, M. G., Latour, L. L., Lee, T. Y., Leigh, R., Lin, W., Lyden, P., Mair, G., Menon, B. K., Michel, P., Mikulik, R., Nogueira, R. G., Ostergaard, L., Pedraza, S., Riedel, C. H., Rowley, H. A., Sanelli, P. C., Sasaki, M., Saver, J. L., Schaefer, P. W., Schellinger, P. D., Tsivgoulis, G., Wechsler, L. R., White, P. M., Zaharchuk, G., Zaidat, O. O., Davis, S. M., Donnan, G. A., Furlan, A. J., Hacke, W., Kang, D. W., Kidwell, C., Thijs, V. N., Thomalla, G. & Warach, S. J., Sep 2013, In : Stroke. 44, 9, p. 2628-2639 12 p.

Research output: Contribution to journalArticle

Distinct mechanisms and timing of language recovery after stroke

Jarso, S., Li, M., Faria, A., Davis, C., Leigh, R., Sebastian, R., Tsapkini, K., Mori, S. & Hillis, A. E., 2013, In : Cognitive Neuropsychology. 30, 7-8, p. 454-475 22 p.

Research output: Contribution to journalArticle

2012

Arrival Time Correction for Dynamic Susceptibility Contrast MR Permeability Imaging in Stroke Patients

Leigh, R., Jen, S. S., Varma, D. D., Hillis, A. E. & Barker, P. B., Dec 20 2012, In : PLoS One. 7, 12, e52656.

Research output: Contribution to journalArticle

Asyntactic comprehension, working memory, and acute ischemia in Broca's area versus angular gyrus

Newhart, M., Trupe, L. A., Gomez, Y., Cloutman, L., Molitoris, J. J., Davis, C., Leigh, R., Gottesman, R. F., Race, D. & Hillis, A. E., Nov 2012, In : Cortex. 48, 10, p. 1288-1297 10 p.

Research output: Contribution to journalArticle

Reperfusion of specific cortical areas is associated with improvement in distinct forms of hemispatial neglect

Khurshid, S., Trupe, L. A., Newhart, M., Davis, C., Molitoris, J. J., Medina, J., Leigh, R. & Hillis, A. E., May 2012, In : Cortex. 48, 5, p. 530-539 10 p.

Research output: Contribution to journalArticle

2011

Detecting penumbral ischemic brain tissue with SWI

Leigh, R. & Barker, P. B., Jan 1 2011, Clinical MR Neuroimaging: Physiological and Functional Techniques, Second Edition. Cambridge University Press, p. 286-287 2 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Formal education, socioeconomic status, and the severity of aphasia after stroke

González-Fernández, M., Davis, C., Molitoris, J. J., Newhart, M., Leigh, R. & Hillis, A. E., Nov 2011, In : Archives of Physical Medicine and Rehabilitation. 92, 11, p. 1809-1813 5 p.

Research output: Contribution to journalArticle