Richard L Huganir

Professor

1979 …2019
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Fingerprint Dive into the research topics where Richard L Huganir is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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AMPA Receptors Medicine & Life Sciences
Phosphorylation Medicine & Life Sciences
Glutamate Receptors Medicine & Life Sciences
Neuronal Plasticity Medicine & Life Sciences
Synapses Medicine & Life Sciences
Neurons Medicine & Life Sciences
N-Methyl-D-Aspartate Receptors Medicine & Life Sciences
Proteins Medicine & Life Sciences

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Research Output 1979 2019

Arc Oligomerization Is Regulated by CaMKII Phosphorylation of the GAG Domain: An Essential Mechanism for Plasticity and Memory Formation

Zhang, W., Chuang, Y. A., Na, Y., Ye, Z., Yang, L., Lin, R., Zhou, J., Wu, J., Qiu, J., Savonenko, A., Leahy, D. J., Huganir, R. L., Linden, D. J. & Worley, P. F., Jul 11 2019, In : Molecular cell. 75, 1, p. 13-25.e5

Research output: Contribution to journalArticle

Calcium-Calmodulin-Dependent Protein Kinase Type 2
Phosphorylation
Retroelements
Hippocampus
Learning

Purkinje cell-specific Grip1/2 knockout mice show increased repetitive self-grooming and enhanced mGluR5 signaling in cerebellum

Mejias, R., Chiu, S-L., Han, M., Rose, R., Gil-Infante, A., Zhao, Y., Huganir, R. L. & Wang, T., Dec 1 2019, In : Neurobiology of Disease. 132, 104602.

Research output: Contribution to journalArticle

Receptor-Interacting Protein Serine-Threonine Kinases
Grooming
Purkinje Cells
Glutamate Receptors
Knockout Mice

BioSITe: A Method for Direct Detection and Quantitation of Site-Specific Biotinylation

Kim, D. I., Cutler, J. A., Na, C-H., Reckel, S., Renuse, S., Madugundu, A. K., Tahir, R., Goldschmidt, H. L., Reddy, K. L., Huganir, R. L., Wu, X., Zachara, N. E., Hantschel, O. & Pandey, A., Feb 2 2018, In : Journal of Proteome Research. 17, 2, p. 759-769 11 p.

Research output: Contribution to journalArticle

Biotinylation
Biotin
Technology
Labeling
Proteins

Identification of long-lived synaptic proteins by proteomic analysis of synaptosome protein turnover

Heo, S., Diering, G. H., Na, C-H., Nirujogi, R. S., Bachman, J. L., Pandey, A. & Huganir, R. L., Apr 17 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 16, p. E3827-E3836

Research output: Contribution to journalArticle

Synaptosomes
Proteomics
Synapses
Proteins
Maintenance

Mitochondrial Stasis Reveals p62-Mediated Ubiquitination in Parkin-Independent Mitophagy and Mitigates Nonalcoholic Fatty Liver Disease

Yamada, T., Murata, D., Adachi, Y., Itoh, K., Kameoka, S., Igarashi, A., Kato, T., Araki, Y., Huganir, R. L., Dawson, T. M., Yanagawa, T., Okamoto, K., Iijima, M. & Sesaki, H., Jan 1 2018, (Accepted/In press) In : Cell Metabolism.

Research output: Contribution to journalArticle

Mitochondrial Degradation
Ubiquitination
Liver
Mitochondria
Cullin Proteins