Rebecca F Gottesman

Professor

20032019
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Research Output 2003 2019

2019

ApoB, small-dense LDL-C, Lp(a), LpPLA2 activity, and cognitive change

Pokharel, Y., Mouhanna, F., Nambi, V., Virani, S. S., Hoogeveen, R., Alonso, A., Heiss, G., Coresh, J., Mosley, T., Gottesman, R. F., Ballantyne, C. M. & Power, M. C., May 28 2019, In : Neurology. 92, 22, p. e2580-e2593

Research output: Contribution to journalArticle

1-Alkyl-2-acetylglycerophosphocholine Esterase
Apolipoproteins B
LDL Cholesterol
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Lipoproteins

A prospective study of serum metabolites and risk of ischemic stroke

Sun, D., Tiedt, S., Yu, B., Jian, X., Gottesman, R. F., Mosley, T. H., Boerwinkle, E., Dichgans, M. & Fornage, M., Apr 16 2019, In : Neurology. 92, 16, p. e1890-e1898

Research output: Contribution to journalArticle

Open Access
Stroke
Prospective Studies
Serum
Dicarboxylic Acids
Metabolomics

Association between white matter hyperintensities, cortical volumes, and late-onset epilepsy

Johnson, E., Krauss, G., Lee, A. K., Schneider, A. L. C., Kucharska-Newton, A. M., Huang, J., Jack, C. R. & Gottesman, R. F., Feb 26 2019, In : Neurology. 92, 9, p. e988-e995

Research output: Contribution to journalArticle

Epilepsy
Atherosclerosis
White Matter
Confidence Intervals
Survival Analysis

Association of Atrial Fibrillation With White Matter Disease

Shao, I. Y., Power, M. C., Mosley, T., Jack, C., Gottesman, R. F., Chen, L. Y., Norby, F. L., Soliman, E. Z. & Alonso, A., Apr 1 2019, In : Stroke. 50, 4, p. 989-991 3 p.

Research output: Contribution to journalArticle

Leukoencephalopathies
Atrial Fibrillation
Linear Models
Social Adjustment
Anisotropy

Association of Brain Magnetic Resonance Imaging Signs With Cognitive Outcomes in Persons With Nonimpaired Cognition and Mild Cognitive Impairment

Wu, A., Sharrett, A. R., Gottesman, R. F., Power, M. C., Mosley, T. H., Jack, C. R., Knopman, D. S., Windham, B. G., Gross, A. L. & Coresh, J., May 3 2019, In : JAMA network open. 2, 5, p. e193359

Research output: Contribution to journalArticle

Open Access
Cognition
Dementia
Magnetic Resonance Imaging
Brain
Alzheimer Disease

Association of Midlife Hypertension with Late-Life Hearing Loss

Reed, N., Huddle, M. G., Betz, J. F., Power, M. C., Pankow, J. S., Gottesman, R. F., Richey Sharrett, A., Mosley, T. H., Lin, F. & Deal, J. A., Jan 1 2019, (Accepted/In press) In : Otolaryngology - Head and Neck Surgery (United States).

Research output: Contribution to journalArticle

Hearing Loss
Epidemiology
Blood Pressure
Hypertension
Hearing

Association of midlife to late-life blood pressure patterns with incident dementia

Walker, K., Sharrett, A. R., Wu, A., Schneider, A. L. C., Albert, M., Lutsey, P. L., Bandeen Roche, K. J., Coresh, J., Gross, A. L., Windham, B. G., Knopman, D. S., Power, M. C., Rawlings, A. M., Mosley, T. H. & Gottesman, R. F., Aug 13 2019, In : JAMA - Journal of the American Medical Association. 322, 6, p. 535-545 11 p.

Research output: Contribution to journalArticle

Dementia
Blood Pressure
Hypertension
Hypotension
Odds Ratio

Association of sickle cell trait with measures of cognitive function and dementia in African Americans

Chen, N., Caruso, C., Alonso, A., Derebail, V. K., Kshirsagar, A. V., Sharrett, A. R., Key, N. S., Gottesman, R. F., Grove, M. L., Bressler, J., Boerwinkle, E., Windham, B. G., Mosley, T. H. & Hyacinth, H. I., Sep 1 2019, In : eNeurologicalSci. 16, 100201.

Research output: Contribution to journalArticle

Open Access
Sickle Cell Trait
African Americans
Cognition
Dementia
Incidence

Associations of echocardiographic features with stroke in those without atrial fibrillation

Johansen, M., Lin, M., Nazarian, S. & Gottesman, R. F., Feb 26 2019, In : Neurology. 92, 9, p. e924-e932

Research output: Contribution to journalArticle

Atrial Fibrillation
Stroke
Logistic Models
Telemetry
Mitral Valve

Atrial Fibrillation and Brain Magnetic Resonance Imaging Abnormalities

Berman, J. P., Norby, F. L., Mosley, T., Soliman, E. Z., Gottesman, R. F., Lutsey, P. L., Alonso, A. & Chen, L. Y., Apr 1 2019, In : Stroke. 50, 4, p. 783-788 6 p.

Research output: Contribution to journalArticle

Atrial Fibrillation
Magnetic Resonance Imaging
Brain
Odds Ratio
Cerebral Infarction

Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function (Nature Communications, (2018), 9, 1, (2098), 10.1038/s41467-018-04362-x)

Davies, G., Lam, M., Harris, S. E., Trampush, J. W., Luciano, M., Hill, W. D., Hagenaars, S. P., Ritchie, S. J., Marioni, R. E., Fawns-Ritchie, C., Liewald, D. C. M., Okely, J. A., Ahola-Olli, A. V., Barnes, C. L. K., Bertram, L., Bis, J. C., Burdick, K. E., Christoforou, A., DeRosse, P., Djurovic, S. & 202 others, Espeseth, T., Giakoumaki, S., Giddaluru, S., Gustavson, D. E., Hayward, C., Hofer, E., Ikram, M. A., Karlsson, R., Knowles, E., Lahti, J., Leber, M., Li, S., Mather, K. A., Melle, I., Morris, D., Oldmeadow, C., Palviainen, T., Payton, A., Pazoki, R., Petrovic, K., Reynolds, C. A., Sargurupremraj, M., Scholz, M., Smith, J. A., Smith, A. V., Terzikhan, N., Thalamuthu, A., Trompet, S., van der Lee, S. J., Ware, E. B., Windham, B. G., Wright, M. J., Yang, J., Yu, J., Ames, D., Amin, N., Amouyel, P., Andreassen, O. A., Armstrong, N. J., Assareh, A. A., Attia, J. R., Attix, D., Avramopoulos, D., Bennett, D. A., Böhmer, A. C., Boyle, P. A., Brodaty, H., Campbell, H., Cannon, T. D., Cirulli, E. T., Congdon, E., Conley, E. D., Corley, J., Cox, S. R., Dale, A. M., Dehghan, A., Dick, D., Dickinson, D., Eriksson, J. G., Evangelou, E., Faul, J. D., Ford, I., Freimer, N. A., Gao, H., Giegling, I., Gillespie, N. A., Gordon, S. D., Gottesman, R. F., Griswold, M. E., Gudnason, V., Harris, T. B., Hartmann, A. M., Hatzimanolis, A., Heiss, G., Holliday, E. G., Joshi, P. K., Kähönen, M., Kardia, S. L. R., Karlsson, I., Kleineidam, L., Knopman, D. S., Kochan, N. A., Konte, B., Kwok, J. B., Le Hellard, S., Lee, T., Lehtimäki, T., Li, S. C., Lill, C. M., Liu, T., Koini, M., London, E., Longstreth, W. T., Lopez, O. L., Loukola, A., Luck, T., Lundervold, A. J., Lundquist, A., Lyytikäinen, L. P., Martin, N. G., Montgomery, G. W., Murray, A. D., Need, A. C., Noordam, R., Nyberg, L., Ollier, W., Papenberg, G., Pattie, A., Polasek, O., Poldrack, R. A., Psaty, B. M., Reppermund, S., Riedel-Heller, S. G., Rose, R. J., Rotter, J. I., Roussos, P., Rovio, S. P., Saba, Y., Sabb, F. W., Sachdev, P. S., Satizabal, C. L., Schmid, M., Scott, R. J., Scult, M. A., Simino, J., Slagboom, P. E., Smyrnis, N., Soumaré, A., Stefanis, N. C., Stott, D. J., Straub, R. E., Sundet, K., Taylor, A. M., Taylor, K. D., Tzoulaki, I., Tzourio, C., Uitterlinden, A., Vitart, V., Voineskos, A. N., Kaprio, J., Wagner, M., Wagner, H., Weinhold, L., Wen, K. H., Widen, E., Yang, Q., Zhao, W., Adams, H. H. H., Arking, D., Bilder, R. M., Bitsios, P., Boerwinkle, E., Chiba-Falek, O., Corvin, A., De Jager, P. L., Debette, S., Donohoe, G., Elliott, P., Fitzpatrick, A. L., Gill, M., Glahn, D. C., Hägg, S., Hansell, N. K., Hariri, A. R., Ikram, M. K., Jukema, J. W., Vuoksimaa, E., Keller, M. C., Kremen, W. S., Launer, L., Lindenberger, U., Palotie, A., Pedersen, N. L., Pendleton, N., Porteous, D. J., Räikkönen, K., Raitakari, O. T., Ramirez, A., Reinvang, I., Rudan, I., Dan Rujescu, R., Schmidt, R., Schmidt, H., Schofield, P. W., Schofield, P. R., Starr, J. M., Steen, V. M., Trollor, J. N., Turner, S. T., Van Duijn, C. M., Villringer, A., Weinberger, D., Weir, D. R., Wilson, J. F., Malhotra, A., McIntosh, A. M., Gale, C. R., Seshadri, S., Mosley, T. H., Bressler, J., Lencz, T. & Deary, I. J., Dec 1 2019, In : Nature communications. 10, 1, 2068.

Research output: Contribution to journalComment/debate

Open Access
document markup languages
HTML
Genetic Loci
loci
lists

Author response: Association of orthostatic hypotension with incident dementia, stroke, and cognitive decline

Rawlings, A. M. & Gottesman, R. F., Apr 9 2019, In : Neurology. 92, 15, 1 p.

Research output: Contribution to journalArticle

Orthostatic Hypotension
Dementia
Stroke
Cognitive Dysfunction

Chronic Systemic Inflammation Is Associated With Symptoms of Late-Life Depression: The ARIC Study

Sonsin-Diaz, N., Gottesman, R. F., Fracica, E., Walston, J. D., Windham, B. G., Knopman, D. S. & Walker, K. A., Jan 1 2019, In : American Journal of Geriatric Psychiatry.

Research output: Contribution to journalArticle

C-Reactive Protein
Depression
Inflammation
Epidemiologic Studies
Confidence Intervals

Cognitive Reserve in Midlife is not Associated with Amyloid-β Deposition in Late-Life

Rawlings, A. M., Sharrett, A. R., Mosley, T. H., Wong, D. F., Knopman, D. S. & Gottesman, R. F., Jan 1 2019, In : Journal of Alzheimer's Disease. 68, 2, p. 517-521 5 p.

Research output: Contribution to journalArticle

Cognitive Reserve
Amyloid
Positron-Emission Tomography
Cognition
Dementia
Delirium
Cardiopulmonary Bypass
Arterial Pressure
Homeostasis
Randomized Controlled Trials

Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting

Chauhan, G., Adams, H. H. H., Satizabal, C. L., Bis, J. C., Teumer, A., Sargurupremraj, M., Hofer, E., Trompet, S., Hilal, S., Smith, A. V., Jian, X., Malik, R., Traylor, M., Pulit, S. L., Amouyel, P., Mazoyer, B., Zhu, Y. C., Kaffashian, S., Schilling, S., Beecham, G. W. & 130 others, Montine, T. J., Schellenberg, G. D., Kjartansson, O., Guonason, V., Knopman, D. S., Griswold, M. E., Windham, B. G., Gottesman, R. F., Mosley, T. H., Schmidt, R., Saba, Y., Schmidt, H., Takeuchi, F., Yamaguchi, S., Nabika, T., Kato, N., Rajan, K. B., Aggarwal, N. T., De Jager, P. L., Evans, D. A., Psaty, B. M., Rotter, J. I., Rice, K., Lopez, O. L., Liao, J., Chen, C., Cheng, C. Y., Wong, T. Y., Ikram, M. K., Van Der Lee, J. S., Amin, N., Chouraki, V., DeStefano, A. L., Aparicio, H. J., Romero, J. R., Maillard, P., DeCarli, C., Wardlaw, J. M., Del Valdes Hernandez, M. C., Luciano, M., Liewald, D., Deary, I. J., Starr, J. M., Bastin, M. E., Maniega, S. M., Slagboom, P. E., Beekman, M., Deelen, J., Uh, H. W., Lemmens, R., Brodaty, H., Wright, M. J., Ames, D., Boncoraglio, G. B., Hopewell, J. C., Beecham, A. H., Blanton, S. H., Wright, C. B., Sacco, R. L., Wen, W., Thalamuthu, A., Armstrong, N. J., Chong, E., Schofield, P. R., Kwok, J. B., Van der Grond, J., Stott, D. J., Ford, I., Jukema, J. W., Vernooij, M. W., Hofman, A., Uitterlinden, A. G., Van der Lugt, A., Wittfeld, K., Grabe, H. J., Hosten, N., Von Sarnowski, B., Volker, U., Levi, C., Jimenez-Conde, J., Sharma, P., Sudlow, C. L. M., Rosand, J., Woo, D., Cole, J. W., Meschia, J. F., Slowik, A., Thijs, V., Lindgren, A., Melander, O., Grewal, R. P., Rundek, T., Rexrode, K., Rothwell, P. M., Arnett, D. K., Jern, C., Johnson, J. A., Benavente, O. R., Wasssertheil-Smoller, S., Lee, J. M., Wong, Q., Mitchell, B. D., Rich, S. S., McArdle, P. F., Geerlings, M. I., Van der Graaf, Y., De Bakker, P. I. W., Asselbergs, F. W., Srikanth, V., Thomson, R., McWhirter, R., Moran, C., Callisaya, M., Phan, T., Rutten-Jacobs, L. C. A., Bevan, S., Tzourio, C., Mather, K. A., Sachdev, P. S., Van Duijn, C. M., Worrall, B. B., Dichgans, M., Kittner, S. J., Markus, H. S., Ikram, M. A., Fornage, M., Launer, L. J., Seshadri, S., Longstreth, W. T. & Debette, S., Jan 29 2019, In : Neurology. 92, 5, p. E486-E503

Research output: Contribution to journalArticle

Open Access
Life Style
Brain
Population
Genome-Wide Association Study
Blood Pressure

High-Sensitive Troponin T, Natriuretic Peptide, and Cognitive Change

Pokharel, Y., Mouhanna, F., Schneider, A. L. C., Rawlings, A. M., Knopman, D. S., Nambi, V., Virani, S. S., Hoogeveen, R. C., Alonso, A., Heiss, G., Coresh, J., Mosley, T., Gottesman, R. F., Selvin, E., Ballantyne, C. & Power, M. C., Jan 1 2019, (Accepted/In press) In : Journal of the American Geriatrics Society.

Research output: Contribution to journalArticle

Natriuretic Peptides
Troponin T
Brain Natriuretic Peptide
Dementia
Verbal Learning

Impaired lung function, lung disease, and risk of incident dementia

Lutsey, P. L., Chen, N., Mirabelli, M. C., Lakshminarayan, K., Knopman, D. S., Vossel, K. A., Gottesman, R. F., Mosley, T. H. & Alonso, A., Jan 1 2019, In : American journal of respiratory and critical care medicine. 199, 11, p. 1385-1396 12 p.

Research output: Contribution to journalArticle

Lung Diseases
Dementia
Lung
Obstructive Lung Diseases
Odds Ratio

Lower carotid revascularization rates after stroke in racial/ethnic minority-serving US hospitals

Faigle, R., Cooper, L. A. & Gottesman, R. F., Jun 4 2019, In : Neurology. 92, 23, p. e2653-e2660

Research output: Contribution to journalArticle

Stroke
Carotid Endarterectomy
Carotid Arteries
Logistic Models
Confidence Intervals

Midlife Systemic Inflammation Is Associated With Frailty in Later Life: The ARIC Study

Walker, K. A., Walston, J. D., Gottesman, R. F., Kucharska-Newton, A., Palta, P. & Windham, B. G., Feb 15 2019, In : The journals of gerontology. Series A, Biological sciences and medical sciences. 74, 3, p. 343-349 7 p.

Research output: Contribution to journalArticle

C-Reactive Protein
Inflammation
Odds Ratio
Confidence Intervals
Leukocyte Count

Migraine Age of Onset and Association With Ischemic Stroke in Late Life: 20 Years Follow-Up in ARIC

Androulakis, X. M., Sen, S., Kodumuri, N., Zhang, T., Grego, J., Rosamond, W., Gottesman, R. F., Shahar, E. & Peterlin, B. L., Jan 1 2019, (Accepted/In press) In : Headache.

Research output: Contribution to journalArticle

Migraine Disorders
Age of Onset
Atherosclerosis
Stroke
Epilepsy

Neural correlates of domain-specific cognitive decline: The ARIC-NCS Study

Schneider, A. L. C., Senjem, M. L., Wu, A., Gross, A. L., Knopman, D. S., Gunter, J. L., Schwarz, C. G., Mosley, T. H., Gottesman, R. F., Sharrett, A. R. & Jack, C. R., Mar 5 2019, In : Neurology. 92, 10, p. e1051-e1063

Research output: Contribution to journalArticle

Atherosclerosis
Executive Function
Brain
Confidence Intervals
Language

Neurovascular and Cognitive Dysfunction in Hypertension

Iadecola, C. & Gottesman, R. F., Mar 29 2019, In : Circulation research. 124, 7, p. 1025-1044 20 p.

Research output: Contribution to journalArticle

Open Access
Hypertension
Dementia
Alzheimer Disease
Pathology
Neuroimaging

Patients with stroke and psychiatric comorbidities have lower carotid revascularization rates

Bongiorno, D. M., Daumit, G. L., Gottesman, R. F. & Faigle, R., May 28 2019, In : Neurology. 92, 22, p. e2514-e2521

Research output: Contribution to journalArticle

Carotid Endarterectomy
Carotid Arteries
Psychiatry
Comorbidity
Stroke

Plasma Metabolites Associated with Brain MRI Measures of Neurodegeneration in Older Adults in the Atherosclerosis Risk in Communities⁻Neurocognitive Study (ARIC-NCS)

Li, D., Misialek, J. R., Jack, C. R., Mielke, M. M., Knopman, D., Gottesman, R. F., Mosley, T. & Alonso, A., Apr 9 2019, In : International journal of molecular sciences. 20, 7

Research output: Contribution to journalArticle

Open Access
arteriosclerosis
Sphingomyelins
metabolites
Magnetic resonance
Metabolites

Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes (Nature Genetics, (2018), 50, 4, (524-537), 10.1038/s41588-018-0058-3)

AFGen Consortium, Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, International Genomics of Blood Pressure (iGEN-BP) Consortium, INVENT Consortium, STARNET, BioBank Japan Cooperative Hospital Group, COMPASS Consortium, EPIC-CVD Consortium, EPIC-InterAct Consortium, International Stroke Genetics Consortium (ISGC), METASTROKE Consortium, Neurology Working Group of the CHARGE Consortium, NINDS Stroke Genetics Network (SiGN), UK Young Lacunar DNA Study & MEGASTROKE Consortium, Jan 1 2019, In : Nature genetics.

Research output: Contribution to journalComment/debate

Open Access
Genome-Wide Association Study
Stroke

Refining Prediction of Atrial Fibrillation-Related Stroke Using the P2-CHA2DS2-VASc Score

Maheshwari, A., Norby, F. L., Roetker, N. S., Soliman, E. Z., Koene, R. J., Rooney, M. R., O'Neal, W. T., Shah, A. M., Claggett, B. L., Solomon, S. D., Alonso, A., Gottesman, R. F., Heckbert, S. R. & Chen, L. Y., Jan 8 2019, In : Circulation. 139, 2, p. 180-191 12 p.

Research output: Contribution to journalArticle

Atrial Fibrillation
Stroke
Atherosclerosis
Electrocardiography
Hospital Records

Serum magnesium and calcium levels in relation to ischemic stroke: Mendelian randomization study

Larsson, S. C., Traylor, M., Burgess, S., Boncoraglio, G. B., Jern, C., Michaëlsson, K., Markus, H. S., Malik, R., Chauhan, G., Sargurupremraj, M., Okada, Y., Mishra, A., Rutten-Jacobs, L., Giese, A. K., Van Der Laan, S. W., Gretarsdottir, S., Anderson, C. D., Chong, M., Adams, H. H. H., Ago, T. & 237 others, Almgren, P., Amouyel, P., Ay, H., Bartz, R. M., Benavente, O. R., Bevan, S., Brown, R. D., Butterworth, A. S., Carrera, C., Carty, C. L., Chasman, D. I., Chen, W. M., Cole, J. W., Correa, A., Cotlarciuc, I., Cruchaga, C., Danesh, J., De Bakker, P. I. W., Destefano, A. L., Hoed, M. D., Duan, Q., Engelter, S. T., Falcone, G. J., Gottesman, R. F., Grewal, R. P., Gudnason, V., Gustafsson, S., Haessler, J., Harris, T. B., Hassan, A., Havulinna, A. S., Heckbert, S. R., Holliday, E. G., Howard, G., Hsu, F. C., Hyacinth, H. I., Ikram, M. A., Ingelsson, E., Irvin, M. R., Jian, X., Jiménez-Conde, J., Johnson, J. A., Jukema, J. W., Kanai, M., Keene, K. L., Kissela, B. M., Kleindorfer, D. O., Kooperberg, C., Kubo, M., Lange, L. A., Langefeld, C. D., Langenberg, C., Launer, L. J., Lee, J. M., Lemmens, R., Leys, D., Lewis, C. M., Lin, W. Y., Lindgren, A. G., Lorentzen, E., Magnusson, P. K., Maguire, J., Manichaikul, A., McArdle, P. F., Meschia, J. F., Mitchell, B. D., Mosley, T. H., Nalls, M. A., Ninomiya, T., O'Donnell, M. J., Psaty, B. M., Pulit, S. L., Rannikmäe, K., Reiner, A. P., Rexrode, K. M., Rice, K., Rich, S. S., Ridker, P. M., Rost, N. S., Rothwell, P. M., Rotter, J. I., Rundek, T., Sacco, R. L., Sakaue, S., Sale, M. M., Salomaa, V., Sapkota, B. R., Schmidt, R., Schmidt, C. O., Schminke, U., Sharma, P., Slowik, A., Sudlow, C. L. M., Tanislav, C., Tatlisumak, T., Taylor, K. D., Thijs, V. N. S., Thorleifsson, G., Thorsteinsdottir, U., Tiedt, S., Trompet, S., Tzourio, C., Van Duijn, C. M., Walters, M., Wareham, N. J., Wassertheil-Smoller, S., Wilson, J. G., Wiggins, K. L., Yang, Q., Yusuf, S., Amin, N., Aparicio, H. S., Arnett, D. K., Attia, J., Beiser, A. S., Berr, C., Buring, J. E., Bustamante, M., Caso, V., Cheng, Y. C., Choi, S. H., Chowhan, A., Cullell, N., Dartigues, J. F., Delavaran, H., Delgado, P., Dörr, M., Engström, G., Ford, I., Gurpreet, W. S., Hamsten, A., Heitsch, L., Hozawa, A., Ibanez, L., Ilinca, A., Ingelsson, M., Iwasaki, M., Jackson, R. D., Jood, K., Jousilahti, P., Kaffashian, S., Kalra, L., Kamouchi, M., Kitazono, T., Kjartansson, O., Kloss, M., Koudstaal, P. J., Krupinski, J., Labovitz, D. L., Laurie, C. C., Levi, C. R., Li, L., Lind, L., Lindgren, C. M., Lioutas, V., Liu, Y. M., Lopez, O. L., Makoto, H., Martinez-Majander, N., Matsuda, K., Minegishi, N., Montaner, J., Morris, A. P., Muiño, E., Müller-Nurasyid, M., Norrving, B., Ogishima, S., Parati, E. A., Peddareddygari, L. R., Pedersen, N. L., Pera, J., Perola, M., Pezzini, A., Pileggi, S., Rabionet, R., Riba-Llena, I., Ribasés, M., Romero, J. R., Roquer, J., Rudd, A. G., Sarin, A. P., Sarju, R., Sarnowski, C., Sasaki, M., Satizabal, C. L., Satoh, M., Sattar, N., Sawada, N., Sibolt, G., Sigurdsson, Á., Smith, A., Sobue, K., Soriano-Tárraga, C., Stanne, T., Stine, O. C., Stott, D. J., Strauch, K., Takai, T., Tanaka, H., Tanno, K., Teumer, A., Tomppo, L., Torres-Aguila, N. P., Touze, E., Tsugane, S., Uitterlinden, A. G., Valdimarsson, E. M., Van Der Lee, S. J., Völzke, H., Wakai, K., Weir, D., Williams, S. R., Wolfe, C. D. A., Wong, Q., Xu, H., Yamaji, T., Sanghera, D. K., Melander, O., Strbian, D., Fernandez-Cadenas, I., Longstreth, W. T., Rolfs, A., Hata, J., Woo, D., Rosand, J., Pare, G., Hopewell, J. C., Saleheen, D., Stefansson, K., Worrall, B. B., Kittner, S. J., Seshadri, S., Fornage, M., Howson, J. M. M., Kamatani, Y., Debette, S. & Dichgans, M., Feb 26 2019, In : Neurology. 92, 9, p. E944-E950

Research output: Contribution to journalArticle

Open Access
Random Allocation
Magnesium
Stroke
Calcium
Serum

Stroke Incidence and Survival in American Indians, Blacks, and Whites: The Strong Heart Study and Atherosclerosis Risk in Communities Study

Muller, C. J., Alonso, A., Forster, J., Vock, D. M., Zhang, Y., Gottesman, R. F., Rosamond, W., Longstreth, W. T. & MacLehose, R. F., Jun 18 2019, In : Journal of the American Heart Association. 8, 12, p. e010229

Research output: Contribution to journalArticle

Open Access
North American Indians
Atherosclerosis
Stroke
Survival
Incidence

Systemic inflammation during midlife and cognitive change over 20 years: The ARIC Study

Walker, K. A., Gottesman, R. F., Wu, A., Knopman, D. S., Gross, A. L., Mosley, T. H., Selvin, E. & Windham, B. G., Mar 12 2019, In : Neurology. 92, 11, p. e1256-e1267

Research output: Contribution to journalArticle

Inflammation
C-Reactive Protein
Biomarkers
Confidence Intervals
Executive Function

The association of late-life diabetes status and hyperglycemia with incident mild cognitive impairment and dementia: The ARIC study

Rawlings, A. M., Sharrett, A. R., Albert, M., Coresh, J., Windham, B. G., Power, M. C., Knopman, D. S., Walker, K., Burgard, S., Mosley, T. H., Gottesman, R. F. & Selvin, E., Jan 1 2019, In : Diabetes care. 42, 7, p. 1248-1264 17 p.

Research output: Contribution to journalArticle

Hyperglycemia
Dementia
Atherosclerosis
Fructosamine
Biomarkers

Understanding Atrial Cardiopathy: an Under-Recognized Contributor to Cardioembolic Stroke

Johansen, M., De Vasconcellos, H. D. & Gottesman, R. F., Jul 1 2019, In : Current Treatment Options in Neurology. 21, 7, 32.

Research output: Contribution to journalReview article

Stroke
Atrial Fibrillation
Therapeutics
Explosions
Secondary Prevention
Open Access
Multilevel Analysis
Cerebral Hemorrhage
Palliative Care
Moving and Lifting Patients

Vascular dysfunction—The disregarded partner of Alzheimer's disease

Sweeney, M. D., Montagne, A., Sagare, A. P., Nation, D. A., Schneider, L. S., Chui, H. C., Harrington, M. G., Pa, J., Law, M., Wang, D. J. J., Jacobs, R. E., Doubal, F. N., Ramirez, J., Black, S. E., Nedergaard, M., Benveniste, H., Dichgans, M., Iadecola, C., Love, S., Bath, P. M. & 49 others, Markus, H. S., Salman, R. A., Allan, S. M., Quinn, T. J., Kalaria, R. N., Werring, D. J., Carare, R. O., Touyz, R. M., Williams, S. C. R., Moskowitz, M. A., Katusic, Z. S., Lutz, S. E., Lazarov, O., Minshall, R. D., Rehman, J., Davis, T. P., Wellington, C. L., González, H. M., Yuan, C., Lockhart, S. N., Hughes, T. M., Chen, C. L. H., Sachdev, P., O'Brien, J. T., Skoog, I., Pantoni, L., Gustafson, D. R., Biessels, G. J., Wallin, A., Smith, E. E., Mok, V., Wong, A., Passmore, P., Barkof, F., Muller, M., Breteler, M. M. B., Román, G. C., Hamel, E., Seshadri, S., Gottesman, R. F., van Buchem, M. A., Arvanitakis, Z., Schneider, J. A., Drewes, L. R., Hachinski, V., Finch, C. E., Toga, A. W., Wardlaw, J. M. & Zlokovic, B. V., Jan 1 2019, In : Alzheimer's and Dementia. 15, 1, p. 158-167 10 p.

Research output: Contribution to journalShort survey

Blood Vessels
Alzheimer Disease
Biomarkers
Cerebrovascular Circulation
Brain Diseases

White matter hyperintensities in vascular contributions to cognitive impairment and dementia (VCID): Knowledge gaps and opportunities

Alber, J., Alladi, S., Bae, H. J., Barton, D. A., Beckett, L. A., Bell, J. M., Berman, S. E., Biessels, G. J., Black, S. E., Bos, I., Bowman, G. L., Brai, E., Brickman, A. M., Callahan, B. L., Corriveau, R. A., Fossati, S., Gottesman, R. F., Gustafson, D. R., Hachinski, V., Hayden, K. M. & 33 others, Helman, A. M., Hughes, T. M., Isaacs, J. D., Jefferson, A. L., Johnson, S. C., Kapasi, A., Kern, S., Kwon, J. C., Kukolja, J., Lee, A., Lockhart, S. N., Murray, A., Osborn, K. E., Power, M. C., Price, B. R., Rhodius-Meester, H. F. M., Rondeau, J. A., Rosen, A. C., Rosene, D. L., Schneider, J. A., Scholtzova, H., Shaaban, C. E., Silva, N. C. B. S., Snyder, H. M., Swardfager, W., Troen, A. M., van Veluw, S. J., Vemuri, P., Wallin, A., Wellington, C., Wilcock, D. M., Xie, S. X. & Hainsworth, A. H., Jan 1 2019, In : Alzheimer's and Dementia: Translational Research and Clinical Interventions. 5, p. 107-117 11 p.

Research output: Contribution to journalShort survey

Open Access
Blood Vessels
Dementia
Alzheimer Disease
Cognitive Dysfunction
White Matter
2018

Adjudication of Transient Ischemic Attack and Stroke in the Multi-Ethnic Study of Atherosclerosis

Longstreth, W. T., Gasca, N. C., Gottesman, R. F., Pearce, J. B. & Sacco, R. L., Jan 11 2018, (Accepted/In press) In : Neuroepidemiology. p. 23-28 6 p.

Research output: Contribution to journalArticle

Transient Ischemic Attack
Atherosclerosis
Stroke
Research Personnel
Observational Studies

Arterial stiffness and dementia pathology: Atherosclerosis Risk in Communities (ARIC)-PET Study

Hughes, T. M., Wagenknecht, L. E., Craft, S., Mintz, A., Heiss, G., Palta, P., Wong, D. F., Zhou, Y., Knopman, D., Mosley, T. H. & Gottesman, R. F., Apr 3 2018, In : Neurology. 90, 14, p. e1248-e1256

Research output: Contribution to journalArticle

Vascular Stiffness
Cerebral Small Vessel Diseases
Dementia
Atherosclerosis
Pathology

Association between Midlife Risk Factors and Late-Onset Epilepsy: Results from the Atherosclerosis Risk in Communities Study

Johnson, E., Krauss, G., Lee, A. K., Schneider, A. L. C., Dearborn, J. L., Kucharska-Newton, A. M., Huang, J., Alonso, A. & Gottesman, R. F., Nov 1 2018, In : JAMA Neurology. 75, 11, p. 1375-1382 8 p.

Research output: Contribution to journalArticle

Epilepsy
Atherosclerosis
Dementia
Life Style
Stroke

Association of atrial fibrillation with cognitive decline and dementia over 20 years: The ARIC-NCS (Atherosclerosis Risk in Communities Neurocognitive Study)

Chen, L. Y., Norby, F. L., Gottesman, R. F., Mosley, T. H., Soliman, E. Z., Agarwal, S. K., Loehr, L. R., Folsom, A. R., Coresh, J. & Alonso, A., Mar 20 2018, In : Journal of the American Heart Association. 7, 6, e007301.

Research output: Contribution to journalArticle

Atrial Fibrillation
Dementia
Atherosclerosis
Stroke
Cognitive Dysfunction

Association of Hospitalization, Critical Illness, and Infection with Brain Structure in Older Adults

Walker, K. A., Gottesman, R. F., Wu, A., Knopman, D. S., Mosley, T. H., Alonso, A., Kucharska-Newton, A. & Brown, C., Jan 1 2018, (Accepted/In press) In : Journal of the American Geriatrics Society.

Research output: Contribution to journalArticle

Critical Illness
Hospitalization
Confidence Intervals
Brain
Infection

Association of left ventricular hypertrophy with cognitive decline and dementia risk over 20 years: The Atherosclerosis Risk In Communities–Neurocognitive Study (ARIC-NCS)

Norby, F. L., Chen, L. Y., Soliman, E. Z., Gottesman, R. F., Mosley, T. H. & Alonso, A., Oct 1 2018, In : American Heart Journal. 204, p. 58-67 10 p.

Research output: Contribution to journalArticle

Left Ventricular Hypertrophy
Dementia
Atherosclerosis
Cognition
Cognitive Dysfunction

Association of orthostatic hypotension with incident dementia, stroke, and cognitive decline

Rawlings, A. M., Juraschek, S. P., Heiss, G., Hughes, T., Meyer, M. L., Selvin, E., Sharrett, A. R., Windham, B. G. & Gottesman, R. F., Aug 21 2018, In : Neurology. 91, 8, p. e759-e768

Research output: Contribution to journalArticle

Orthostatic Hypotension
Dementia
Stroke
Blood Pressure
Confidence Intervals

Associations of echocardiography markers and vascular brain lesions: The ARIC study

Johansen, M., Shah, A. M., Lirette, S. T., Griswold, M., Mosley, T. H., Solomon, S. D. & Gottesman, R. F., Dec 1 2018, In : Journal of the American Heart Association. 7, 24, e008992.

Research output: Contribution to journalArticle

Blood Vessels
Echocardiography
Atherosclerosis
Odds Ratio
Confidence Intervals

Atrial cardiopathy and the risk of ischemic stroke in the chs (cardiovascular health study)

Kamel, H., Bartz, T. M., Elkind, M. S. V., Okin, P. M., Thacker, E. L., Patton, K. K., Stein, P. K., De Filippi, C. R., Gottesman, R. F., Heckbert, S. R., Kronmal, R. A., Soliman, E. Z. & Longstreth, W. T., Apr 1 2018, In : Stroke. 49, 4, p. 980-986 7 p.

Research output: Contribution to journalArticle

Atrial Fibrillation
Stroke
Myocardial Infarction
Health
Brain Natriuretic Peptide

Carotid intima-media thickness and silent brain infarctions in a biracial cohort: The atherosclerosis risk in communities (ARIC) Study

Caughey, M. C., Qiao, Y., Windham, B. G., Gottesman, R. F., Mosley, T. H. & Wasserman, B. A., Jul 16 2018, In : American Journal of Hypertension. 31, 8, p. 869-875 7 p.

Research output: Contribution to journalArticle

Brain Infarction
Carotid Intima-Media Thickness
Common Carotid Artery
Atherosclerosis
Confidence Intervals

Cerebral Small Vessel, But Not Large Vessel Disease, Is Associated With Impaired Cerebral Autoregulation During Cardiopulmonary Bypass: A Retrospective Cohort Study

Nomura, Y., Faegle, R., Hori, D., Al-Qamari, A., Nemeth, A. J., Gottesman, R. F., Yenokyan, G., Brown, C. & Hogue, C. W., Dec 1 2018, In : Anesthesia and Analgesia. 127, 6, p. 1314-1322 9 p.

Research output: Contribution to journalArticle

Cardiopulmonary Bypass
Homeostasis
Cohort Studies
Retrospective Studies
Cerebrovascular Circulation

Cerebrovascular Alterations in Alzheimer Disease

Iadecola, C. & Gottesman, R. F., Aug 3 2018, In : Circulation Research. 123, 4, p. 406-408 3 p.

Research output: Contribution to journalArticle

Blood-Brain Barrier
Blood Vessels
Dementia
Alzheimer Disease
Neurons

Cognitive impairment and intracranial atherosclerotic stenosis in general population

Suri, M. F. K., Zhou, J., Qiao, Y., Chu, H., Qureshi, A. I., Mosley, T., Gottesman, R. F., Wruck, L., Sharrett, A. R., Alonso, A. & Wasserman, B. A., Apr 3 2018, In : Neurology. 90, 14, p. e1240-e1247

Research output: Contribution to journalArticle

Pathologic Constriction
Dementia
Population
Atherosclerosis
Odds Ratio

Comorbid Psychiatric Disease Is Associated With Lower Rates of Thrombolysis in Ischemic Stroke

Bongiorno, D. M., Daumit, G. L., Gottesman, R. F. & Faigle, R., Mar 1 2018, In : Stroke. 49, 3, p. 738-740 3 p.

Research output: Contribution to journalArticle

Psychiatry
Stroke
Bipolar Disorder
Psychotic Disorders
Schizophrenia

Exome Chip Analysis Identifies Low-Frequency and Rare Variants in MRPL38 for White Matter Hyperintensities on Brain Magnetic Resonance Imaging

neuroCHARGE Working Group, Aug 1 2018, In : Stroke. 49, 8, p. 1812-1819 8 p.

Research output: Contribution to journalArticle

Exome
Magnetic Resonance Imaging
Brain
Meta-Analysis
Cerebral Small Vessel Diseases