Ray-Whay Yen

Research Associate

1984 …2018
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  • 9 Similar Profiles
Methyltransferases Medicine & Life Sciences
DNA Medicine & Life Sciences
DNA Methylation Medicine & Life Sciences
Methylation Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
CpG Islands Medicine & Life Sciences
Epigenomics Medicine & Life Sciences
Azacitidine Medicine & Life Sciences

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Research Output 1984 2018

DNA Methylation Patterns Separate Senescence from Transformation Potential and Indicate Cancer Risk

Xie, W., Kagiampakis, I., Pan, L., Zhang, Y. W., Murphy, L., Tao, Y., Kong, X., Kang, B., Xia, L., Carvalho, F. L. F., Sen, S., Chiu Yen, R. W., Zahnow, C. A., Ahuja, N., Baylin, S. B. & Easwaran, H. Feb 12 2018 In : Cancer cell. 33, 2, p. 309-321.e5

Research output: Contribution to journalArticle

DNA Methylation
Methylation
Developmental Genes
Neoplasms
Epigenomics

Acetylation Enhances TET2 Function in Protecting against Abnormal DNA Methylation during Oxidative Stress

Zhang, Y. W., Wang, Z., Xie, W., Cai, Y., Xia, L., Easwaran, H., Luo, J., Yen, R. W. C., Li, Y. & Baylin, S. B. Jan 19 2017 In : Molecular Cell. 65, 2, p. 323-335 13 p.

Research output: Contribution to journalArticle

DNA Methylation
Acetylation
Oxidative Stress
5-Methylcytosine
CpG Islands

CHD4 Has Oncogenic Functions in Initiating and Maintaining Epigenetic Suppression of Multiple Tumor Suppressor Genes

Xia, L., Huang, W., Bellani, M., Seidman, M. M., Wu, K., Fan, D., Nie, Y., Cai, Y., Zhang, Y. W., Yu, L. R., Li, H., Zahnow, C. A., Xie, W., Chiu Yen, R. W., Rassool, F. V. & Baylin, S. B. May 8 2017 In : Cancer Cell. 31, 5, p. 653-668.e7

Research output: Contribution to journalArticle

Tumor Suppressor Genes
Epigenomics
DNA Repair
Colorectal Neoplasms
DNA

Critical threshold levels of DNA methyltransferase 1 are required to maintain DNA methylation across the genome in human cancer cells

Cai, Y., Tsai, H. C., Yen, R. W. C., Zhang, Y. W., Kong, X., Wang, W., Xia, L. & Baylin, S. B. Apr 1 2017 In : Genome Research. 27, 4, p. 533-544 12 p.

Research output: Contribution to journalArticle

Methyltransferases
Human Genome
DNA Methylation
DNA
Neoplasms

Epigenetic Therapy Ties MYC Depletion to Reversing Immune Evasion and Treating Lung Cancer

Topper, M. J., Vaz, M., Chiappinelli, K. B., DeStefano Shields, C. E., Niknafs, N., Yen, R. W. C., Wenzel, A., Hicks, J., Ballew, M., Stone, M., Tran, P. T., Zahnow, C. A., Hellmann, M. D., Anagnostou, V., Strissel, P. L., Strick, R., Velculescu, V. E. & Baylin, S. B. Nov 30 2017 In : Cell. 171, 6, p. 1284-1300.e21

Research output: Contribution to journalArticle

Immune Evasion
T-cells
Epigenomics
Non-Small Cell Lung Carcinoma
Lung Neoplasms