Ray-Whay Yen

Research Associate

School of Medicine

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Methyltransferases Medicine & Life Sciences

DNA Medicine & Life Sciences

DNA Methylation Medicine & Life Sciences

Methylation Medicine & Life Sciences

Neoplasms Medicine & Life Sciences

CpG Islands Medicine & Life Sciences

Epigenomics Medicine & Life Sciences

Azacitidine Medicine & Life Sciences

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Research Output 1984 2018

26 Article

DNA Methylation Patterns Separate Senescence from Transformation Potential and Indicate Cancer Risk

Xie, W., Kagiampakis, I., Pan, L., Zhang, Y. W., Murphy, L., Tao, Y., Kong, X., Kang, B., Xia, L., Carvalho, F. L. F., Sen, S., Chiu Yen, R. W., Zahnow, C. A., Ahuja, N., Baylin, S. B. & Easwaran, H. Feb 12 2018 In : Cancer cell. 33, 2, p. 309-321.e5

Research output: Contribution to journal › Article

DNA Methylation

Methylation

Developmental Genes

Neoplasms

Epigenomics

Acetylation Enhances TET2 Function in Protecting against Abnormal DNA Methylation during Oxidative Stress

Zhang, Y. W., Wang, Z., Xie, W., Cai, Y., Xia, L., Easwaran, H., Luo, J., Yen, R. W. C., Li, Y. & Baylin, S. B. Jan 19 2017 In : Molecular Cell. 65, 2, p. 323-335 13 p.

Research output: Contribution to journal › Article

DNA Methylation

Acetylation

Oxidative Stress

5-Methylcytosine

CpG Islands

CHD4 Has Oncogenic Functions in Initiating and Maintaining Epigenetic Suppression of Multiple Tumor Suppressor Genes

Xia, L., Huang, W., Bellani, M., Seidman, M. M., Wu, K., Fan, D., Nie, Y., Cai, Y., Zhang, Y. W., Yu, L. R., Li, H., Zahnow, C. A., Xie, W., Chiu Yen, R. W., Rassool, F. V. & Baylin, S. B. May 8 2017 In : Cancer Cell. 31, 5, p. 653-668.e7

Research output: Contribution to journal › Article

Tumor Suppressor Genes

Epigenomics

DNA Repair

Colorectal Neoplasms

DNA

Critical threshold levels of DNA methyltransferase 1 are required to maintain DNA methylation across the genome in human cancer cells

Cai, Y., Tsai, H. C., Yen, R. W. C., Zhang, Y. W., Kong, X., Wang, W., Xia, L. & Baylin, S. B. Apr 1 2017 In : Genome Research. 27, 4, p. 533-544 12 p.

Research output: Contribution to journal › Article

Methyltransferases

Human Genome

DNA Methylation

DNA

Neoplasms

Epigenetic Therapy Ties MYC Depletion to Reversing Immune Evasion and Treating Lung Cancer

Topper, M. J., Vaz, M., Chiappinelli, K. B., DeStefano Shields, C. E., Niknafs, N., Yen, R. W. C., Wenzel, A., Hicks, J., Ballew, M., Stone, M., Tran, P. T., Zahnow, C. A., Hellmann, M. D., Anagnostou, V., Strissel, P. L., Strick, R., Velculescu, V. E. & Baylin, S. B. Nov 30 2017 In : Cell. 171, 6, p. 1284-1300.e21

Research output: Contribution to journal › Article

Immune Evasion

T-cells

Epigenomics

Non-Small Cell Lung Carcinoma

Lung Neoplasms