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Ray-Whay Yen

Research Associate

1984 …2019
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Methyltransferases Medicine & Life Sciences
DNA Methylation Medicine & Life Sciences
DNA Medicine & Life Sciences
Methylation Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
CpG Islands Medicine & Life Sciences
Epigenomics Medicine & Life Sciences
Genes Medicine & Life Sciences

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Research Output 1984 2019

Aging-like Spontaneous Epigenetic Silencing Facilitates Wnt Activation, Stemness, and Braf V600E -Induced Tumorigenesis

Tao, Y., Kang, B., Petkovich, D. A., Bhandari, Y. R., In, J., Stein-O'Brien, G., Kong, X., Xie, W., Zachos, N., Maegawa, S., Vaidya, H., Brown, S., Chiu Yen, R. W., Shao, X., Thakor, J., Lu, Z., Cai, Y., Zhang, Y., Mallona, I., Peinado, M. A. & 6 others, Zahnow, C. A., Ahuja, N., Fertig, E., Issa, J. P., Baylin, S. B. & Easwaran, H., Feb 11 2019, In : Cancer cell. 35, 2, p. 315-328.e6

Research output: Contribution to journal › Article

Epigenomics
Organoids
Colon
Carcinogenesis
Clustered Regularly Interspaced Short Palindromic Repeats

Defining UHRF1 Domains that Support Maintenance of Human Colon Cancer DNA Methylation and Oncogenic Properties

Kong, X., Chen, J., Xie, W., Brown, S. M., Cai, Y., Wu, K., Fan, D., Nie, Y., Yegnasubramanian, S., Tiedemann, R. L., Tao, Y., Yen, R-W., Topper, M. J., Zahnow, C., Easwaran, H., Rothbart, S. B., Xia, L. & Baylin, S. B., Apr 15 2019, In : Cancer cell. 35, 4, p. 633-648.e7

Research output: Contribution to journal › Article

DNA Methylation
Colonic Neoplasms
Colorectal Neoplasms
Ubiquitin-Protein Ligases
Tumor Suppressor Genes

DNA Methylation Patterns Separate Senescence from Transformation Potential and Indicate Cancer Risk

Xie, W., Kagiampakis, I., Pan, L., Zhang, Y., Murphy, L., Tao, Y., Kong, X., Kang, B., Xia, L., Carvalho, F. L. F., Sen, S., Yen, R-W., Zahnow, C., Ahuja, N., Baylin, S. B. & Easwaran, H., Feb 12 2018, In : Cancer Cell. 33, 2, p. 309-321.e5

Research output: Contribution to journal › Article

DNA Methylation
Methylation
Developmental Genes
Neoplasms
Epigenomics

Acetylation Enhances TET2 Function in Protecting against Abnormal DNA Methylation during Oxidative Stress

Zhang, Y., Wang, Z., Xie, W., Cai, Y., Xia, L., Easwaran, H., Luo, J., Yen, R-W., Li, Y. & Baylin, S. B., Jan 19 2017, In : Molecular Cell. 65, 2, p. 323-335 13 p.

Research output: Contribution to journal › Article

DNA Methylation
Acetylation
Oxidative Stress
5-Methylcytosine
CpG Islands

CHD4 Has Oncogenic Functions in Initiating and Maintaining Epigenetic Suppression of Multiple Tumor Suppressor Genes

Xia, L., Huang, W., Bellani, M., Seidman, M. M., Wu, K., Fan, D., Nie, Y., Cai, Y., Zhang, Y., Yu, L. R., Li, H., Zahnow, C., Xie, W., Yen, R-W., Rassool, F. V. & Baylin, S. B., May 8 2017, In : Cancer Cell. 31, 5, p. 653-668.e7

Research output: Contribution to journal › Article

Tumor Suppressor Genes
Epigenomics
DNA Repair
Colorectal Neoplasms
DNA