Raul Chavez-Valdez

Research output

Research output per year 2005 2011 2012 2019 2021 2022 2023 2024

• 59 Article
• 5 Comment/debate
• 2 Chapter
• 2 Review article
• 1 More
  • 1 Editorial

Research output per year

Research output per year

Search results

• 2024

  Factors affecting early childhood growth in hypoxic-ischemic encephalopathy treated with hypothermia

  Jayakumar, S., Burton, V. J., Perin, J., Asafu-Adjaye, D., Cristofalo, E., Northington, F., Chavez-Valdez, R., Leppert, M., Allen, M. & Gerner, G., 2024, (Accepted/In press) In: Journal of Perinatology.

  Research output: Contribution to journal › Article › peer-review

  • Brain Hypoxia-Ischemia 100%
  • Hypothermia 80%
  • Induced Hypothermia 71%
  • Head 42%
  • Growth 38%

• Quantification of Diffusion Magnetic Resonance Imaging for Prognostic Prediction of Neonatal Hypoxic-Ischemic Encephalopathy

  Onda, K., Chavez-Valdez, R., Graham, E. M., Everett, A. D., Northington, F. J. & Oishi, K., Feb 1 2024, In: Developmental Neuroscience. 46, 1, p. 55-68 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Brain Hypoxia-Ischemia 100%
  • Diffusion Magnetic Resonance Imaging 90%
  • Diffusion Tensor Imaging 58%
  • Anisotropy 29%
  • Edema 20%
• 2023

  Dysregulation of ErbB4 Signaling Pathway in the Dorsal Hippocampus after Neonatal Hypoxia-Ischemia and Late Deficits in PV⁺ Interneurons, Synaptic Plasticity and Working Memory

  Spahic, H., Parmar, P., Miller, S., Emerson, P. C., Lechner, C., St. Pierre, M., Rastogi, N., Nugent, M., Duck, S. A., Kirkwood, A. & Chavez-Valdez, R., Jan 2023, In: International journal of molecular sciences. 24, 1, 508.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • hippocampus 100%
  • ischemia 99%
  • Parvalbumins 87%
  • hypoxia 85%
  • hypothermia 85%

• Evaluating Injury Severity in Neonatal Encephalopathy Using Automated Quantitative Electroencephalography Analysis: A Pilot Study

  Catenaccio, E., Smith, R. J., Chavez-Valdez, R., Burton, V. J., Graham, E., Parkinson, C., Vaidya, D., Tekes, A., Northington, F. J., Everett, A. D., Stafstrom, C. E. & Ritzl, E. K., 2023, (Accepted/In press) In: Developmental Neuroscience.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Brain Diseases 100%
  • Electroencephalography 89%
  • Induced Hypothermia 72%
  • Psychological Power 66%
  • Wounds and Injuries 51%

• Interaction of hydrocortisone and illness severity on head growth in cohort of ELBW infants

  Chen, H., Aziz, K. B., Spahic, H., Miller, S., Guryildirim, M., Sellers, A., Brooks, S., Kilborn, A., Everett, A. D., Northington, F. J., Stafstrom, C. E. & Chavez-Valdez, R., Dec 2023, In: Pediatric research. 94, 6, p. 1958-1965 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Extremely Low Birth Weight Infant 100%
  • Hydrocortisone 60%
  • Head 49%
  • Growth 34%
  • Gestational Age 7%

• Management of Hypoxic-Ischemic Encephalopathy Using Measures Other Than Therapeutic Hypothermia

  Burnsed, J. & Chavez-Valdez, R., Jan 1 2023, Principles of Neonatology. Elsevier, p. 406-420 15 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Brain Hypoxia-Ischemia 100%
  • Induced Hypothermia 95%
  • Brain Diseases 48%
  • Nervous System 20%
  • Consciousness 13%

• Proceedings of the 14th International Newborn Brain Conference: Neuroprotection strategies in the neonate

  Abdurajan, S., Ågren, J., Alt, J., Axelin, A., Bäcke, P., Balashova, E., Thernström Blomqvist, Y., Burckhard, Z., Burnsed, J., Cornaz Buros, S., Chavez-Valdez, R., Chen, M., Dickie, J., Dietz, R., Dingman, A., Doucette, L., El-Dib, M., Shibiny, H., Flock, D., Ganal, S., & 32 othersGorse, K., Guo, J., Harrison, S., Herrmann, J., Ionov, O., Jackson, T., Janesko-Feldman, K., Jantzie, L., June, A., Kathiresh, S., Kirtbaya, A., Klein, A., Kochanek, P., Kuter, N., Marlicz, M., Martin, L. J., Matysik, W., Munster, C., Northington, F. J., Quilinan, N., Rais, R., Schöberlein, A., Sharafutdinova, D., Suvorov, M. S. I., Suvorova, J., Szakmar, E., Tiemeier, E., Tran, P., Trigo, N. F., Turnbill, V., Ushakova, L. & Vagni, V., 2023, In: Journal of Neonatal-Perinatal Medicine. 16, s1, p. S21-S31

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Proceedings of the 14th International Newborn Brain Conference: Neonatal Neurocritical Care, seizures, and continuous aEEG and /or EEG monitoring

  Abramsky, R., Acun, C., Alt, J., Aly, H., Arad, N., Baak, L. M., Bakalar, D., Balasingham, T., Bammler, T., Benders, M. J. N. L., Benitez, D., Boni, E., Boylan, G., Campbell, E., Castri, P., Chandrashekar, P., Chavez-Valdez, R., Chen, M., Chiodin, E., Comstock, B., & 92 othersDamien, J., de Vries, L. S., de Vries, L., Dickman, J., Doucette, L., Duckworth, E., Echeverria-Palacio, C., El Jalbout, R., El-Dib, M., Elshibiny, H., Flock, D., Gallagher, A., Gasperoni, E., Glass, H., Harteman, J. C., Harvey-Jones, K., Hazan, I., Heagerty, P., Inder, T., Jantzie, L., Juul, S., Karnati, S., Kute, N., Lacaille, H., Lange, F., Lemmers, P. M. A., Liu, W., Llaguno, N., Magalhães, M., Mambule, I., Marandyuk, B., Marks, K., Martin, L. J., Massaro, A., Mathieson, S., McCaul, M. C., Meehan, C., Meledin, I., Menna, E., Menzato, F., Mintoft, A., Mitra, S., Nakimuli, A., Nanyunya, C., Norris, G., Northington, F. J., Numis, A., O'Reilly, J. J., Ortiz, S., Padiyar, S., Paquette, N., Parmeggiani, L., Patrizi, S., Pavlidis, E., Pellegrin, S., Penn, A. A., Petitpas, L., Pinchefsky, E., Ponta, A., Puthuraya, J. P. S., Rais, R., Robertson, N. J., Rodrigues, D., Salandin, M., Salzbank, J., Sánchez, L., Schalij, N., Serrano-Tabares, C., Shany, E., Staffler, A., Steggerda, S., Tachtsidis, I., Tann, C., Tataranno, M. L., Trabatti, C., Tremblay, J., Tromp, S., Tucker, K., Turnbill, V., Vacher, C. M., van Bel, F., van der Aa, N. E., Van Meurs, K., Van Steenis, A., van Wyk, L., Vannasing, P., Variane, G., Verma, V., Voldal, E., Wagenaar, N., Wu, Y. & Wustoff, C., 2023, In: Journal of Neonatal-Perinatal Medicine. 16, s1, p. S33-S62

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Serum brain injury biomarkers are gestationally and post-natally regulated in non-brain injured neonates

  Brooks, S., Friedes, B. D., Northington, F., Graham, E., Tekes, A., Burton, V. J., Gerner, G., Zhu, J., Chavez-Valdez, R., Vaidya, D. & Everett, A. D., Jun 2023, In: Pediatric research. 93, 7, p. 1943-1954 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Brain Injuries 100%
  • Gestational Age 73%
  • Biomarkers 67%
  • Serum 47%
  • Brain-Derived Neurotrophic Factor 29%

• Sexual Dimorphism in the Closure of the Hippocampal Postnatal Critical Period of Synaptic Plasticity after Intrauterine Growth Restriction: Link to Oligodendrocyte and Glial Dysregulation

  Nugent, M., St. Pierre, M., Brown, A., Nassar, S., Parmar, P., Kitase, Y., Duck, S. A., Pinto, C., Jantzie, L., Fung, C. & Chavez-Valdez, R., Oct 1 2023, In: Developmental Neuroscience. 45, 5, p. 234-254 21 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Oligodendroglia 100%
  • Fetal Growth Retardation 99%
  • Neuronal Plasticity 86%
  • Sex Characteristics 85%
  • Neuroglia 80%

• Unbiased Quantitative Single-Cell Morphometric Analysis to Identify Microglia Reactivity in Developmental Brain Injury

  St. Pierre, M., Duck, S. A., Nazareth, M., Fung, C., Jantzie, L. L. & Chavez-Valdez, R., Apr 2023, In: Life. 13, 4, 899.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • brain damage 100%
  • Single-Cell Analysis 82%
  • Developmental 73%
  • Pipeline 70%
  • neuroglia 66%

• Worse Outcomes From HIE Treatment Associated With Extreme Glycemic States

  Chavez-Valdez, R., Aziz, K., Burton, V. J. & Northington, F. J., Oct 1 2023, In: Pediatrics. 152, 4, e2023062521.

  Research output: Contribution to journal › Comment/debate › peer-review
• 2022

  Basal forebrain magnocellular cholinergic systems are damaged in mice following neonatal hypoxia-ischemia

  Northington, F. J., Kratimenos, P., Turnbill, V., Flock, D. L., Asafu-Adjaye, D., Chavez-Valdez, R. & Martin, L. J., Jun 2022, In: Journal of Comparative Neurology. 530, 8, p. 1148-1163 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Basal Forebrain 100%
  • Basal Nucleus of Meynert 98%
  • Choline O-Acetyltransferase 97%
  • Cholinergic Agents 74%
  • Hypoxia 62%

• Challenges and Opportunities in Developmental Brain Injuries

  Chavez-Valdez, R. & Levison, S. W., Sep 1 2022, In: Developmental Neuroscience. 44, 4-5, p. 175-176 2 p.

  Research output: Contribution to journal › Editorial › peer-review

  Open Access

• Clonidine for sedation in infants during therapeutic hypothermia with neonatal encephalopathy: pilot study

  Gauda, E. B., Chavez-Valdez, R., Northington, F. J., Lee, C. K. K., Rudek, M. A., Guglieri-Lopez, B. & Ivaturi, V., Mar 2022, In: Journal of Perinatology. 42, 3, p. 319-327 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Induced Hypothermia 100%
  • Clonidine 91%
  • Brain Diseases 76%
  • Morphine 47%
  • Brain Hypoxia-Ischemia 39%

• Correction to: Clonidine for sedation in infants during therapeutic hypothermia with neonatal encephalopathy: pilot study (Journal of Perinatology, (2022), 42, 3, (319-327), 10.1038/s41372-021-01151-1)

  Gauda, E. B., Chavez-Valdez, R., Northington, F. J., Lee, C. K. K., Rudek, M. A., Guglieri-Lopez, B. & Ivaturi, V., Mar 2022, In: Journal of Perinatology. 42, 3, p. 422 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Perinatology 100%
  • Induced Hypothermia 79%
  • Clonidine 72%
  • Brain Diseases 61%

• Development of a composite diffusion tensor imaging score correlating with short-term neurological status in neonatal hypoxic–ischemic encephalopathy

  Onda, K., Catenaccio, E., Chotiyanonta, J., Chavez-Valdez, R., Meoded, A., Soares, B. P., Tekes, A., Spahic, H., Miller, S. C., Parker, S. J., Parkinson, C., Vaidya, D. M., Graham, E. M., Stafstrom, C. E., Everett, A. D., Northington, F. J. & Oishi, K., Aug 2 2022, In: Frontiers in Neuroscience. 16, 931360.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Diffusion Tensor Imaging 100%
  • Brain Diseases 84%
  • Induced Hypothermia 46%
  • Anisotropy 43%
  • National Institute of Child Health and Human Development (U.S.) 37%

• Intrauterine Growth Restriction Disrupts the Postnatal Critical Period of Synaptic Plasticity in the Mouse Dorsal Hippocampus in a Model of Hypertensive Disease of Pregnancy

  St. Pierre, M., Rastogi, N., Brown, A., Parmar, P., Lechner, C., Fung, C. & Chavez-Valdez, R., Sep 1 2022, In: Developmental Neuroscience. 44, 4-5, p. 214-232 19 p.

  Research output: Contribution to journal › Article › peer-review

  • Fetal Growth Retardation 100%
  • Neuronal Plasticity 86%
  • Hippocampus 72%
  • Pregnancy 54%
  • polysialyl neural cell adhesion molecule 21%

• Iron supplementation and the risk of bronchopulmonary dysplasia in extremely low gestational age newborns

  Independent Medical Monitor, PENUT Trial Consortium, PENUT Co-Investigators, PENUT Research Coordinators, University of Washington Data Coordinating Center, PENUT Executive Committee & Follow Up Committee, 2022, (Accepted/In press) In: Pediatric research.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Bronchopulmonary Dysplasia 100%
  • Gestational Age 69%
  • Iron 66%
  • Newborn Infant 61%
  • Small Intestine 36%

• Perinatal Inflammatory Biomarkers and Respiratory Disease in Preterm Infants

  Collaco, J. M., McGrath-Morrow, S. A., Griffiths, M., Chavez-Valdez, R., Parkinson, C., Zhu, J., Northington, F. J., Graham, E. M. & Everett, A. D., Jul 2022, In: Journal of Pediatrics. 246, p. 34-39.e3

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Premature Infants 100%
  • Bronchopulmonary Dysplasia 86%
  • Interleukin-8 82%
  • Vascular Endothelial Growth Factor A 74%
  • Biomarkers 67%
• 2021

  Accumulation of PSA-NCAM marks nascent neurodegeneration in the dorsal hippocampus after neonatal hypoxic-ischemic brain injury in mice

  Chavez-Valdez, R., Lechner, C., Emerson, P., Northington, F. J. & Martin, L. J., May 2021, In: Journal of Cerebral Blood Flow and Metabolism. 41, 5, p. 1039-1057 19 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • polysialic acid 100%
  • Neural Cell Adhesion Molecules 84%
  • Brain Injuries 61%
  • Hippocampus 51%
  • Hypoxia 28%
  3 Scopus citations

• Association between Term Equivalent Brain Magnetic Resonance Imaging and 2-Year Outcomes in Extremely Preterm Infants: A Report from the Preterm Erythropoietin Neuroprotection Trial Cohort

  Preterm Erythropoietin Neuroprotection (PENUT) Trial Consortium, Dec 2021, In: Journal of Pediatrics. 239, p. 117-125.e6

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Extremely Premature Infants 100%
  • Erythropoietin 72%
  • Neuroprotection 72%
  • Magnetic Resonance Imaging 45%
  • Brain Injuries 40%

• Intrauterine growth restriction causes abnormal embryonic dentate gyrus neurogenesis in mouse offspring that leads to adult learning and memory deficits

  Brown, A. S., Wieben, M., Murdock, S., Chang, J., Dizon, M. L. V., Pierre, M. S., Chavez-Valdez, R., Dorsky, R. I. & Fung, C. M., Sep 1 2021, In: eNeuro. 8, 5, ENEURO.0062-21.2021.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Fetal Growth Retardation 100%
  • Dentate Gyrus 99%
  • Memory Disorders 96%
  • Neurogenesis 96%
  • Learning 66%

• Later cooling within 6 h and temperatures outside 33–34 °C are not associated with dysfunctional autoregulation during hypothermia for neonatal encephalopathy

  Gilmore, M. M., Tekes, A., Perin, J., Parkinson, C., Spahic, H., Chavez-Valdez, R., Northington, F. J. & Lee, J. K., Jan 2021, In: Pediatric research. 89, 1, p. 223-230 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Hypothermia 100%
  • Brain Diseases 91%
  • Homeostasis 70%
  • Temperature 68%
  • Brain Injuries 46%
  1 Scopus citations

• Sex specific correlation between GABAergic disruption in the dorsal hippocampus and flurothyl seizure susceptibility after neonatal hypoxic-ischemic brain injury

  Lechner, C. R., McNally, M. A., St. Pierre, M., Felling, R. J., Northington, F. J., Stafstrom, C. E. & Chavez-Valdez, R., Jan 2021, In: Neurobiology of Disease. 148, 105222.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Flurothyl 100%
  • Brain Injuries 56%
  • Hippocampus 46%
  • Seizures 45%
  • Hypoxia 34%

• The Impact of Erythropoietin on Short- and Long-Term Kidney-Related Outcomes in Neonates of Extremely Low Gestational Age. Results of a Multicenter, Double-Blind, Placebo-Controlled Randomized Clinical Trial

  the PENUT Trial Consortium, 2021, (Accepted/In press) In: Journal of Pediatrics.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Erythropoietin 100%
  • Placebos 65%
  • Randomized Controlled Trials 64%
  • Blood Pressure 60%
  • Gestational Age 54%
  1 Scopus citations

• Therapeutic Hypothermia Modulates the Relationships Between Indicators of Severity of Neonatal Hypoxic Ischemic Encephalopathy and Serum Biomarkers

  Chavez-Valdez, R., Miller, S., Spahic, H., Vaidya, D., Parkinson, C., Dietrick, B., Brooks, S., Gerner, G. J., Tekes, A., Graham, E. M., Northington, F. J. & Everett, A. D., Nov 2 2021, In: Frontiers in Neurology. 12, 748150.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Brain Hypoxia-Ischemia 100%
  • Induced Hypothermia 95%
  • Biomarkers 50%
  • Glial Fibrillary Acidic Protein 46%
  • Serum 35%

• Transfusions and neurodevelopmental outcomes in extremely low gestation neonates enrolled in the PENUT Trial: a randomized clinical trial

  for the PENUT Consortium, PENUT Site PIs, Non-Author Participants, PENUT Consortium Co-investigators, PENUT Research Coordinators, University of Washington Data Coordinating Center, PENUT Executive Committee & PENUT Medical Monitor, Jul 2021, In: Pediatric research. 90, 1, p. 109-116 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Erythropoietin 100%
  • Erythrocyte Transfusion 88%
  • Newborn Infant 72%
  • Randomized Controlled Trials 64%
  • Pregnancy 57%
  4 Scopus citations

• Wavelet Autoregulation Monitoring Identifies Blood Pressures Associated With Brain Injury in Neonatal Hypoxic-Ischemic Encephalopathy

  Liu, X., Tekes, A., Perin, J., Chen, M. W., Soares, B. P., Massaro, A. N., Govindan, R. B., Parkinson, C., Chavez-Valdez, R., Northington, F. J., Brady, K. M. & Lee, J. K., Apr 28 2021, In: Frontiers in Neurology. 12, 662839.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Brain Hypoxia-Ischemia 100%
  • Brain Injuries 74%
  • Homeostasis 56%
  • Hemoglobins 49%
  • Blood Pressure 49%
• 2020

  Head ultrasound resistive indices are associated with brain injury on diffusion tensor imaging magnetic resonance imaging in neonates with hypoxic-ischemic encephalopathy

  Snyder, E. J., Perin, J., Chavez-Valdez, R., Northington, F. J., Lee, J. K. & Tekes, A., 2020, In: Journal of computer assisted tomography. 44, 5, p. 687-691 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Brain Hypoxia-Ischemia 100%
  • Diffusion Tensor Imaging 87%
  • Brain Injuries 74%
  • Induced Hypothermia 63%
  • Head 56%
  1 Scopus citations
• 2019

  An Inhibitor of the Mitochondrial Permeability Transition Pore Lacks Therapeutic Efficacy Following Neonatal Hypoxia Ischemia in Mice

  Fang, J., Chavez-Valdez, R., Flock, D. L., Avaritt, O., Saraswati, M., Robertson, C., Martin, L. J. & Northington, F. J., May 15 2019, In: Neuroscience. 406, p. 202-211 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • mitochondrial permeability transition pore 100%
  • Hypoxia 57%
  • Ischemia 54%
  • Brain Injuries 46%
  • Calcium 33%
  5 Scopus citations

• Calbindin-1 Expression in the Hippocampus following Neonatal Hypoxia-Ischemia and Therapeutic Hypothermia and Deficits in Spatial Memory

  Goffigan-Holmes, J., Sanabria, D., Diaz, J., Flock, D. & Chavez-Valdez, R., Jul 1 2019, In: Developmental Neuroscience. 40, 5-6, p. 508-522 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Calbindin 1 100%
  • Induced Hypothermia 81%
  • Spatial Memory 72%
  • Hippocampus 52%
  • Hypoxia 51%
  4 Scopus citations

• Evidence for sexual dimorphism in the response to TLR3 activation in the developing neonatal mouse brain: A pilot study

  Chavez-Valdez, R., Mottahedin, A., Stridh, L., Yellowhair, T. R., Jantzie, L. L., Northington, F. J. & Mallard, C., 2019, In: Frontiers in Physiology. 10, MAR, 306.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Poly I-C 100%
  • Sex Characteristics 81%
  • Brain 42%
  • Thalamus 17%
  • Chemokines 16%
  6 Scopus citations

• Repurposing azithromycin for neuroprotection in neonates

  Chavez-Valdez, R., Oct 1 2019, In: Pediatric research. 86, 4, p. 423-424 2 p.

  Research output: Contribution to journal › Comment/debate › peer-review

• Seizure Susceptibility Correlates with Brain Injury in Male Mice Treated with Hypothermia after Neonatal Hypoxia-Ischemia

  McNally, M. A., Chavez-Valdez, R., Felling, R. J., Flock, D. L., Northington, F. J. & Stafstrom, C. E., Jul 1 2019, In: Developmental Neuroscience. 40, 5-6, p. 576-585 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Hypothermia 100%
  • Brain Injuries 92%
  • Induced Hypothermia 79%
  • Hypoxia 75%
  • Seizures 74%
  2 Scopus citations

• The Role of Diffusion Tensor Imaging in Detecting Hippocampal Injury Following Neonatal Hypoxic-Ischemic Encephalopathy

  Salas, J., Reddy, N., Orru, E., Carson, K. A., Chavez-Valdez, R., Burton, V. J., Stafstrom, C. E., Northington, F. J. & Huisman, T. A. G. M., Mar 1 2019, In: Journal of Neuroimaging. 29, 2, p. 252-259 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Brain Hypoxia-Ischemia 100%
  • Diffusion Tensor Imaging 87%
  • Wounds and Injuries 37%
  • Newborn Infant 14%
  • Anisotropy 7%
  4 Scopus citations
• 2018

  Cerebral Autoregulation and Conventional and Diffusion Tensor Imaging Magnetic Resonance Imaging in Neonatal Hypoxic-Ischemic Encephalopathy

  Carrasco, M., Perin, J., Jennings, J. M., Parkinson, C., Gilmore, M. M., Chavez-Valdez, R., Massaro, A. N., Koehler, R. C., Northington, F. J., Tekes, A. & Lee, J. K., May 2018, In: Pediatric Neurology. 82, p. 36-43 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Brain Hypoxia-Ischemia 100%
  • Diffusion Tensor Imaging 87%
  • Arterial Pressure 62%
  • Homeostasis 56%
  • Magnetic Resonance Imaging 51%
  12 Scopus citations

• Delayed injury of hippocampal interneurons after neonatal hypoxia-ischemia and therapeutic hypothermia in a murine model

  Chavez-Valdez, R., Emerson, P., Goffigan-Holmes, J., Kirkwood, A., Martin, L. J. & Northington, F. J., Aug 2018, In: Hippocampus. 28, 8, p. 617-630 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Induced Hypothermia 100%
  • Interneurons 85%
  • Hypoxia 63%
  • Ischemia 60%
  • Parvalbumins 39%
  14 Scopus citations

• Neonatal encephalopathy

  Chavez-Valdez, R. & Diaz, J., Jan 1 2018, The 5-Minute Pediatric Consult, 8th Edition. Wolters Kluwer Health, p. 634-635 2 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
• 2017

  Optimizing Cerebral Autoregulation May Decrease Neonatal Regional Hypoxic-Ischemic Brain Injury

  Lee, J. K., Poretti, A., Perin, J., Huisman, T. A. G. M., Parkinson, C., Chavez-Valdez, R., O'Connor, M., Reyes, M., Armstrong, J., Jennings, J. M., Gilmore, M. M., Koehler, R. C., Northington, F. J. & Tekes, A., Jul 1 2017, In: Developmental Neuroscience. 39, 1-4, p. 248-256 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Brain Injuries 100%
  • Asphyxia 78%
  • Homeostasis 75%
  • Brain Hypoxia-Ischemia 66%
  • Blood Pressure 65%
  36 Scopus citations

• Relationships between cerebral autoregulation and markers of kidney and liver injury in neonatal encephalopathy and therapeutic hypothermia

  Lee, J. K., Perin, J., Parkinson, C., O'Connor, M., Gilmore, M. M., Reyes, M., Armstrong, J., Jennings, J. M., Northington, F. J. & Chavez-Valdez, R., Aug 1 2017, In: Journal of Perinatology. 37, 8, p. 938-942 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Induced Hypothermia 100%
  • Brain Diseases 76%
  • Homeostasis 59%
  • Aspartate Aminotransferases 54%
  • Blood Pressure 51%
  8 Scopus citations

• Sex-specific associations between cerebrovascular blood pressure autoregulation and cardiopulmonary injury in neonatal encephalopathy and therapeutic hypothermia

  Chavez-Valdez, R., O'Connor, M., Perin, J., Reyes, M., Armstrong, J., Parkinson, C., Gilmore, M., Jennings, J., Northington, F. J. & Lee, J. K., May 1 2017, In: Pediatric research. 81, 5, p. 759-766 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Induced Hypothermia 100%
  • Brain Diseases 76%
  • Arterial Pressure 65%
  • Homeostasis 59%
  • Blood Pressure 51%
  9 Scopus citations

• Therapeutic Hypothermia Provides Variable Protection against Behavioral Deficits after Neonatal Hypoxia-Ischemia: A Potential Role for Brain-Derived Neurotrophic Factor

  Diaz, J., Abiola, S., Kim, N., Avaritt, O., Flock, D., Yu, J., Northington, F. J. & Chavez-Valdez, R., Jul 1 2017, In: Developmental Neuroscience. 39, 1-4, p. 257-272 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Induced Hypothermia 100%
  • Brain-Derived Neurotrophic Factor 85%
  • Hypoxia 63%
  • Ischemia 60%
  • Prosencephalon 31%
  22 Scopus citations
• 2016

  Endoplasmic reticulum pathology and stress response in neurons precede programmed necrosis after neonatal hypoxia-ischemia

  Chavez-Valdez, R., Flock, D. L., Martin, L. J. & Northington, F. J., Feb 1 2016, In: International Journal of Developmental Neuroscience. 48, p. 58-70 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Endoplasmic Reticulum Stress 100%
  • Endoplasmic Reticulum 85%
  • necrostatin-1 85%
  • Hypoxia 70%
  • Necrosis 69%
  34 Scopus citations

• Lipopolysaccharide exposure during the early postnatal period adversely affects the structure and function of the developing rat carotid body

  Master, Z. R., Porzionato, A., Kesavan, K., Mason, A., Chavez-Valdez, R., Shirahata, M. & Gauda, E. B., Sep 2016, In: Journal of applied physiology. 121, 3, p. 816-827 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Carotid Body 100%
  • Lipopolysaccharides 63%
  • Newborn Infant 34%
  • Premature Infants 28%
  • Inflammation 26%
  16 Scopus citations

• Mechanisms of modulation of cytokine release by human cord blood monocytes exposed to high concentrations of caffeine

  Chavez-Valdez, R., Ahlawat, R., Wills-Karp, M. & Gauda, E. B., Jul 1 2016, In: Pediatric research. 80, 1, p. 101-109 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Caffeine 100%
  • Fetal Blood 94%
  • Monocytes 79%
  • Cytokines 59%
  • Phosphoric Diester Hydrolases 49%
  9 Scopus citations
• 2015

  Acute paraplegia in a preterm infant with cerebral sinovenous thrombosis

  Hobbs, J., Tekes, A., Klein, J., Lemmon, M., Felling, R. J. & Chavez-Valdez, R., Jun 28 2015, In: Journal of Perinatology. 35, 6, p. 460-462 3 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Intracranial Thrombosis 100%
  • Premature Infants 72%
  • Spinal Cord 61%
  • Infarction 46%
  • Heart Arrest 18%

• A pilot cohort study of cerebral autoregulation and 2-year neurodevelopmental outcomes in neonates with hypoxic-ischemic encephalopathy who received therapeutic hypothermia

  Burton, V. J., Gerner, G., Cristofalo, E., Chung, S. E., Jennings, J. M., Parkinson, C., Koehler, R. C., Chavez-Valdez, R., Johnston, M. V., Northington, F. J. & Lee, J. K., Oct 20 2015, In: BMC neurology. 15, 1, 209.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Brain Hypoxia-Ischemia 100%
  • Induced Hypothermia 95%
  • Newborn Infant 59%
  • Homeostasis 56%
  • Cohort Studies 52%
  39 Scopus citations

• Correction: Hypoxia-ischemia and therapeutic hypothermia in the neonatal mouse brain - A longitudinal study

  Burnsed, J. C., Chavez-Valdez, R., Hossain, M. S., Kesavan, K., Martin, L. J. & Zhang, J., May 26 2015, In: PloS one. 10, 5, e0129406.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access
  2 Scopus citations

• Hypoxia-ischemia and therapeutic hypothermia in the neonatal mouse brain - A longitudinal study

  Burnsed, J. C., Chavez-Valdez, R., Hossain, M. S., Kesavan, K., Martin, L. J., Zhang, J. & Northington, F. J., Mar 16 2015, In: PloS one. 10, 3, e0118889.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Induced Hypothermia 100%
  • longitudinal studies 97%
  • hypothermia 94%
  • ischemia 89%
  • hypoxia 74%
  38 Scopus citations