Ralph P Tufano

Professor

19992018
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Research Output 1999 2018

2018

American thyroid association guidelines and statements: Past, present, and future

Sawka, A. M., Carty, S. E., Haugen, B. R., Hennessey, J. V., Kopp, P. A., Pearce, E. N., Sosa, J. A., Tufano, R. P. & Jonklaas, J. Jun 1 2018 In : Thyroid. 28, 6, p. 692-706 15 p.

Research output: Contribution to journalArticle

Practice Guidelines
Thyroid Gland
Guidelines
Advisory Committees
Publications

Are preoperative sestamibi scans useful for identifying ectopic parathyroid glands in patients with expected multigland parathyroid disease?

Karipineni, F., Sahli, Z., Somervell, H., Mathur, A., Prescott, J. D., Tufano, R. P. & Zeiger, M. A. Jan 1 2018 In : Surgery (United States). 163, 1, p. 35-41 7 p.

Research output: Contribution to journalArticle

Parathyroid Diseases
Parathyroid Glands
Hyperparathyroidism
Multiple Endocrine Neoplasia
Lithium
Thyroid Neoplasms
Dissection
Neck
Recurrent Laryngeal Nerve
Parathyroid Glands
Laryngoscopy
Vocal Cords
Thyroid Gland
Incidence
Neck Dissection

Thyroidectomy in patients who have undergone gastric bypass surgery

Goldenberg, D., Ferris, R. L., Shindo, M. L., Shaha, A., Stack, B. & Tufano, R. P. Jan 1 2018 (Accepted/In press) In : Head and Neck.

Research output: Contribution to journalArticle

Gastric Bypass
Thyroidectomy
Hypocalcemia
Morbid Obesity
Bariatric Surgery
2017

Characterizing the operative findings and utility of intraoperative parathyroid hormone (IOPTH) monitoring in patients with normal baseline IOPTH and normohormonal primary hyperparathyroidism

Trinh, G., Noureldine, S. I., Russell, J. O., Agrawal, N., Lopez, M., Prescott, J. D., Zeiger, M. A. & Tufano, R. P. Jan 1 2017 In : Surgery. 161, 1, p. 78-86 9 p.

Research output: Contribution to journalArticle

Primary Hyperparathyroidism
Physiologic Monitoring
Parathyroid Hormone
Reference Values
Parathyroidectomy

Comparative analysis of 2 robotic thyroidectomy procedures: Transoral versus bilateral axillo-breast approach

Chai, Y. J., Kim, H. Y., Kim, H. K., Jun, S. H., Dionigi, G., Anuwong, A., Richmon, J. D. & Tufano, R. P. Jan 1 2017 (Accepted/In press) In : Head and Neck.

Research output: Contribution to journalArticle

Thyroid Nodule
Thyroidectomy
Robotics
Thyroid Neoplasms
Breast

Indications and extent of central neck dissection for papillary thyroid cancer: An American Head and Neck Society Consensus Statement

Agrawal, N., Evasovich, M. R., Kandil, E., Noureldine, S. I., Felger, E. A., Tufano, R. P., Kraus, D. H., Orloff, L. A., Grogan, R., Angelos, P., Stack, B. C., McIver, B. & Randolph, G. W. Jul 1 2017 In : Head and Neck. 39, 7, p. 1269-1279 11 p.

Research output: Contribution to journalArticle

Neck Dissection
Consensus
Neck
Hope
Head and Neck Neoplasms

Intraoperative PTH May Not Be Necessary in the Management of Primary Hyperparathyroidism Even with Only One Positive or Only Indeterminate Preoperative Localization Studies

Najafian, A., Kahan, S., Olson, M. T., Tufano, R. P. & Zeiger, M. A. Feb 21 2017 (Accepted/In press) In : World Journal of Surgery. p. 1-6 6 p.

Research output: Contribution to journalArticle

Primary Hyperparathyroidism
Intraoperative Monitoring
Adenoma
Retrospective Studies
Databases

Neuromonitoring in endoscopic and robotic thyroidectomy

Dionigi, G., Kim, H. Y., Wu, C. W., Lavazza, M., Materazzi, G., Lombardi, C. P., Anuwong, A. & Tufano, R. P. Jun 1 2017 In : Updates in Surgery. 69, 2, p. 171-179 9 p.

Research output: Contribution to journalReview article

Thyroidectomy
Robotics
Paralysis
Laryngeal Nerves
Vagus Nerve Stimulation

Online and call center referral for endocrine surgical pathology within institutions

Dhillon, V. K., Al Khadem, M. G., Tufano, R. P. & Russell, J. O. 2017 (Accepted/In press) In : Laryngoscope.

Research output: Contribution to journalArticle

Surgical Pathology
Referral and Consultation
Otolaryngology
Neck
Thyroid Gland

Postoperative IPTH compared with IPTH gradient as predictors of post-thyroidectomy hypocalcemia

Al Khadem, M. G., Rettig, E. M., Dhillon, V. K., Russell, J. O. & Tufano, R. P. 2017 (Accepted/In press) In : Laryngoscope.

Research output: Contribution to journalArticle

Hypocalcemia
Thyroidectomy
Parathyroid Hormone
Area Under Curve
Odds Ratio

Preoperative information for thyroid surgery

Dhillon, V. K., Russell, J. O., Al Khadem, M. G. & Tufano, R. P. 2017 In : Gland Surgery. 6, 5, p. 482-487 6 p.

Research output: Contribution to journalReview article

Thyroid Gland
Informed Consent
Technology
Intraoperative Monitoring
Thyroidectomy

RAS Mutations, and RET/PTC and PAX8/PPAR-gamma Chromosomal Rearrangements Are Also Prevalent in Benign Thyroid Lesions: Implications Thereof and A Systematic Review

Najafian, A., Noureldine, S., Azar, F., Atallah, C., Trinh, G., Schneider, E. B., Tufano, R. P. & Zeiger, M. A. Jan 1 2017 In : Thyroid. 27, 1, p. 39-48 10 p.

Research output: Contribution to journalReview article

Factor IX
PPAR gamma
Thyroid Gland
Mutation
Neoplasms
Recurrent Laryngeal Nerve
Thyroidectomy
Dissection

Transoral endoscopic thyroidectomy via a vestibular approach: why and how?

Dionigi, G., Chai, Y. J., Tufano, R. P., Anuwong, A. & Kim, H. Y. Oct 16 2017 (Accepted/In press) In : Endocrine. p. 1-5 5 p.

Research output: Contribution to journalArticle

Thyroidectomy
Neck
Neoplasm Metastasis
Goiter
Robotics

Transoral robotic thyroidectomy: a preclinical feasibility study using the da Vinci Xi platform

Russell, J. O., Noureldine, S. I., Al Khadem, M. G., Chaudhary, H. A., Day, A. T., Kim, H. Y., Tufano, R. P. & Richmon, J. D. Feb 2 2017 (Accepted/In press) In : Journal of Robotic Surgery. p. 1-6 6 p.

Research output: Contribution to journalArticle

Thyroidectomy
Feasibility Studies
Robotics
Cadaver
Thyroid Gland

Transoral thyroidectomy: Why is it needed?

Dionigi, G., Lavazza, M., Wu, C. W., Sun, H., Liu, X. L., Tufano, R. P., Kim, H. Y., Richmon, J. D. & Anuwong, A. Jun 1 2017 In : Gland Surgery. 6, 3, p. 272-276 5 p.

Research output: Contribution to journalReview article

Thyroidectomy
Thyroid Gland
Nodular Goiter
Insufflation
Endoscopes

Transoral thyroidectomy: advantages and limitations

Dionigi, G., Tufano, R. P., Russell, J., Kim, H. Y., Piantanida, E. & Anuwong, A. Apr 21 2017 (Accepted/In press) In : Journal of Endocrinological Investigation. p. 1-5 5 p.

Research output: Contribution to journalArticle

Thyroidectomy
Thyroid Gland
Nodular Goiter
Endoscopes
Cicatrix

Transoral thyroidectomy and parathyroidectomy – A North American series of robotic and endoscopic transoral approaches to the central neck

Russell, J. O., Clark, J., Noureldine, S. I., Anuwong, A., Al Khademh, M. G., Yub Kim, H., Dhillon, V. K., Dionigi, G., Tufano, R. P. & Richmon, J. D. Aug 1 2017 In : Oral Oncology. 71, p. 75-80 6 p.

Research output: Contribution to journalArticle

Parathyroidectomy
Thyroidectomy
Robotics
Neck
Thyroid Gland

Utility of preoperative fine needle aspiration in parotid lesions

Eytan, D. F., Yin, L. X., Maleki, Z., Koch, W. M., Tufano, R. P., Eisele, D. W., Boahene, K. D. O., Fakhry, C., Bishop, J. A., Westra, W. H. & Gourin, C. G. 2017 (Accepted/In press) In : Laryngoscope.

Research output: Contribution to journalArticle

Fine Needle Biopsy
Neck Dissection
Medical Records
Decision Making
Cohort Studies
2016

Active surveillance for papillary thyroid microcarcinoma: New challenges and opportunities for the health care system

Haser, G. C. , Tuttle, R. M. , Su, H. K. , Alon, E. E. , Bergman, D. , Bernet, V. , Brett, E. , Cobin, R. , Dewey, E. H. , Doherty, G. , Dos Reis, L. L. , Harris, J. , Klopper, J. , Lee, S. L. , Levine, R. A. , Lepore, S. J. , Likhterov, I. , Lupo, M. A. , Machac, J. , Mechanick, J. I. & 12 others Mehra, S., Milas, M., Orloff, L. A., Randolph, G., Revenson, T. A., Roberts, K. J., Ross, D. S., Rowe, M. E., Smallridge, R. C., Terris, D., Tufano, R. P. & Urken, M. L. 2016 In : Endocrine Practice. 22, 5, p. 62-611 550 p.

Research output: Contribution to journalReview article

Delivery of Health Care
Thyroid Gland
Quality of Life
Psychology
Papillary Thyroid Microcarcinoma

Assessment of vocal fold function using transcutaneous laryngeal ultrasonography and flexible laryngoscopy

Kandil, E., Deniwar, A., Noureldine, S. I., Hammad, A. Y., Mohamed, H., Al-Qurayshi, Z. & Tufano, R. P. Jan 1 2016 In : JAMA Otolaryngology - Head and Neck Surgery. 142, 1, p. 74-78 5 p.

Research output: Contribution to journalArticle

Laryngoscopy
Vocal Cords
Ultrasonography
Thyroid Gland
Tertiary Care Centers

Association between magnesium disorders and hypocalcemia following thyroidectomy

Nellis, J. C., Tufano, R. P. & Gourin, C. G. Sep 1 2016 In : Otolaryngology - Head and Neck Surgery. 155, 3, p. 402-410 9 p.

Research output: Contribution to journalArticle

Hypocalcemia
Thyroidectomy
Magnesium
Costs and Cost Analysis
Length of Stay

Cetuximab activity in dysplastic lesions of the upper aerodigestive tract

Khan, Z., Epstein, J. B., Marur, S., Gillespie, M. B., Feldman, L., Tsai, H. L., Zhang, Z., Wang, H., Sciubba, J., Ferris, R., Grandis, J. R., Gibson, M., Koch, W., Tufano, R., Westra, W., Tsottles, N., Ozawa, H., Chung, C. & Califano, J. A. Feb 1 2016 In : Oral Oncology. 53, p. 60-66 7 p.

Research output: Contribution to journalArticle

Observation
Therapeutics
Nonparametric Statistics
Phase II Clinical Trials
Cetuximab

Corrigendum to "Cetuximab activity in dysplastic lesions of the upper aerodigestive tract" [Oral Oncol. 53 (2016) 60-66]

Khan, Z., Epstein, J. B., Marur, S., Boyd Gillespie, M., Feldman, L., Tsai, H. L., Zhang, Z., Wang, H., Sciubba, J., Ferris, R. L., Grandis, J. R., Gibson, M., Koch, W., Tufano, R., Westra, W., Tsottles, N., Ozawa, H., Chung, C. H. & Califano, J. A. 2016 (Accepted/In press) In : Oral Oncology.

Research output: Contribution to journalArticle

Cetuximab

Endoscopic retroauricular thyroidectomy: preliminary results

Byeon, H. K., Holsinger, F. C., Tufano, R. P., Park, J. H., Sim, N. S., Kim, W. S., Choi, E. C. & Koh, Y. W. Jan 1 2016 In : Surgical Endoscopy and Other Interventional Techniques. 30, 1, p. 355-365 11 p.

Research output: Contribution to journalArticle

Thyroidectomy
Rhytidoplasty
Conversion to Open Surgery
Intraoperative Complications
Robotics

Evaluation of the effect of diagnostic molecular testing on the surgical decision-making process for patients with thyroid nodules

Noureldine, S. I., Najafian, A., Han, P. A., Olson, M. T., Genther, D. J., Schneider, E. B., Prescott, J. D., Agrawal, N., Mathur, A., Zeiger, M. A. & Tufano, R. P. Jul 1 2016 In : JAMA Otolaryngology - Head and Neck Surgery. 142, 7, p. 676-682 7 p.

Research output: Contribution to journalArticle

Molecular Diagnostic Techniques
Thyroid Nodule
Decision Making
Referral and Consultation
Peer Review

Gene expression classifier testing and the surgical decision-making process for patients with thyroid nodules - Reply

Noureldine, S. I., Zeiger, M. A. & Tufano, R. P. Aug 1 2016 In : JAMA Otolaryngology - Head and Neck Surgery. 142, 8, p. 807 1 p.

Research output: Contribution to journalLetter

Thyroid Nodule
Decision Making
Gene Expression

Improving the adoption of thyroid cancer clinical practice guidelines

Likhterov, I. , Tuttle, R. M. , Haser, G. C. , Su, H. K. , Bergman, D. , Alon, E. E. , Bernet, V. , Brett, E. , Cobin, R. , Dewey, E. H. , Doherty, G. , Dos Reis, L. L. , Klopper, J. , Lee, S. L. , Lupo, M. A. , Machac, J. , Mechanick, J. I. , Milas, M. , Orloff, L. , Randolph, G. & 6 others Ross, D. S., Rowe, M. E., Smallridge, R., Terris, D., Tufano, R. P. & Urken, M. L. 2016 (Accepted/In press) In : Laryngoscope.

Research output: Contribution to journalArticle

Thyroid Neoplasms
Practice Guidelines
Point-of-Care Systems
Patient Care Management
Guideline Adherence

New recommendations for extent of thyroidectomy and active surveillance for the treatment of differentiated thyroid cancer

Tufano, R. P., Shindo, M. & Shaha, A. R. Jul 1 2016 In : JAMA Otolaryngology - Head and Neck Surgery. 142, 7, p. 625-626 2 p.

Research output: Contribution to journalShort survey

Thyroidectomy
Thyroid Neoplasms

Recurrent laryngeal nerve injury with incomplete loss of electromyography signal during monitored thyroidectomy—evaluation and outcome

Wu, C. W., Hao, M., Tian, M., Dionigi, G., Tufano, R. P., Kim, H. Y., Jung, K. Y., Liu, X., Sun, H., Lu, I. C., Chang, P. Y. & Chiang, F. Y. Feb 17 2016 (Accepted/In press) In : Langenbeck's Archives of Surgery. p. 1-9 9 p.

Research output: Contribution to journalArticle

Recurrent Laryngeal Nerve Injuries
Recurrent Laryngeal Nerve
Thyroidectomy
Electromyography
Paralysis
Thyroid Nodule
Neck Dissection
Cell Biology
Decision Making

Thyroidectomy vs active surveillance for subcentimeter papillary thyroid cancers - The cost conundrum

Kandil, E., Noureldine, S. I. & Tufano, R. P. Jan 1 2016 In : JAMA Otolaryngology - Head and Neck Surgery. 142, 1, p. 9-10 2 p.

Research output: Contribution to journalArticle

Watchful Waiting
Thyroidectomy
Thyroid Neoplasms
Patient Selection
Carcinoma

Thyroid lymphoma: Differential diagnosis and management

Noureldine, S. I., Kandil, E. & Tufano, R. P. Jan 1 2016 Thyroid Cancer: A Case-Based Approach. Springer International Publishing, p. 403-410 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Lymphoma
Thyroid Gland
Differential Diagnosis

Transoral endoscopic thyroidectomy via vestibular approach: Operative steps and video

Dionigi, G., Bacuzzi, A., Lavazza, M., Inversini, D., Pappalardo, V., Boni, L., Rausei, S., Barczynski, M., Tufano, R. P., Kim, H. Y. & Anuwong, A. 2016 In : Gland Surgery. 5, 6, p. 625-627 3 p.

Research output: Contribution to journalArticle

Thyroidectomy
Thyroid Gland
Nodular Goiter
Insufflation
Endoscopes
2015

American Thyroid Association Statement on Surgical Application of Molecular Profiling for Thyroid Nodules: Current Impact on Perioperative Decision Making

Ferris, R. L., Baloch, Z., Bernet, V., Chen, A., Fahey, T. J., Ganly, I., Hodak, S. P., Kebebew, E., Patel, K. N., Shaha, A., Steward, D. L., Tufano, R. P., Wiseman, S. M. & Carty, S. E. Jul 1 2015 In : Thyroid. 25, 7, p. 760-768 9 p.

Research output: Contribution to journalArticle

Thyroid Nodule
Routine Diagnostic Tests
Decision Making
Thyroid Gland
Unnecessary Procedures

Association of Hashimoto's thyroiditis and thyroid cancer

Noureldine, S. I. & Tufano, R. P. Jan 12 2015 In : Current Opinion in Oncology. 27, 1, p. 21-25 5 p.

Research output: Contribution to journalArticle

Hashimoto Disease
Thyroid Neoplasms
Thyroid Gland
Lymphoma
Thyroidectomy

Database and registry research in thyroid cancer: Striving for a new and improved national thyroid cancer database

Mehra, S. , Tuttle, R. M. , Milas, M. , Orloff, L. , Bergman, D. , Bernet, V. , Brett, E. , Cobin, R. , Doherty, G. , Judson, B. L. , Klopper, J. , Lee, S. , Lupo, M. , Machac, J. , Mechanick, J. I. , Randolph, G. , Ross, D. S. , Smallridge, R. , Terris, D. , Tufano, R. & 5 others Alon, E., Clain, J., Dosreis, L., Scherl, S. & Urken, M. L. Feb 1 2015 In : Thyroid. 25, 2, p. 157-168 12 p.

Research output: Contribution to journalArticle

Thyroid Neoplasms
Registries
Databases
Research
Neoplasms

Detection of somatic mutations and HPV in the saliva and plasma of patients with head and neck squamous cell carcinomas

Wang, Y. , Springer, S. , Mulvey, C. L. , Silliman, N. , Schaefer, J. , Sausen, M. , James, N. , Rettig, E. M. , Guo, T. , Pickering, C. R. , Bishop, J. A. , Chung, C. H. , Califano, J. A. , Eisele, D. W. , Fakhry, C. , Gourin, C. G. , Ha, P. K. , Kang, H. , Kiess, A. , Koch, W. M. & 12 others Myers, J. N., Quon, H., Richmon, J. D., Sidransky, D., Tufano, R. P., Westra, W. H., Bettegowda, C., Diaz, L. A., Papadopoulos, N., Kinzler, K. W., Vogelstein, B. & Agrawal, N. Jun 24 2015 In : Science Translational Medicine. 7, 293, 293ra104

Research output: Contribution to journalArticle

Saliva
Mutation
DNA
Neoplasms
Mouth

Effect of gene expression classifier molecular testing on the surgical decision-making process for patients with thyroid nodules

Noureldine, S. I., Olson, M. T., Agrawal, N., Prescott, J. D., Zeiger, M. A. & Tufano, R. P. Dec 1 2015 In : JAMA Otolaryngology - Head and Neck Surgery. 141, 12, p. 1082-1088 7 p.

Research output: Contribution to journalArticle

Thyroid Nodule
Decision Making
Gene Expression
Referral and Consultation
Case Management

Electrophysiologic monitoring correlates of recurrent laryngeal nerve heat thermal injury in a porcine model

Lin, Y. C., Dionigi, G., Randolph, G. W., Lu, I. C., Chang, P. Y., Tsai, S. Y., Kim, H. Y., Lee, H. Y., Tufano, R. P., Sun, H., Liu, X., Chiang, F. Y. & Wu, C. W. Aug 1 2015 In : Laryngoscope. 125, 8, p. E283-E290

Research output: Contribution to journalArticle

Recurrent Laryngeal Nerve
Swine
Hot Temperature
Recurrent Laryngeal Nerve Injuries
Wounds and Injuries

Ethical responsibilities of caring for patients with incidental thyroid nodules

Tufano, R. P., Noureldine, S. I. & Angelos, P. May 1 2015 In : Thyroid. 25, 5, p. 467-468 2 p.

Research output: Contribution to journalArticle

Medical Ethics
Thyroid Nodule
Incidental Findings

Impact of positional changes in neural monitoring endotracheal tube on amplitude and latency of electromyographic response in monitored thyroid surgery: Results from the Porcine Experiment

Kim, H. Y., Tufano, R. P., Randolph, G., Barczyński, M., Wu, C. W., Chiang, F. Y., Liu, X., Masuoka, H., Miyauchi, A., Park, S. Y., Kwak, H. Y., Lee, H. Y. & Dionigi, G. 2015 (Accepted/In press) In : Head and Neck.

Research output: Contribution to journalArticle

Electromyography
Reaction Time
Thyroid Gland
Swine
Recurrent Laryngeal Nerve Injuries

Incidental thyroid nodules and thyroid cancer: Considerations before determining management

Tufano, R. P., Noureldine, S. I. & Angelos, P. Jun 1 2015 In : JAMA Otolaryngology - Head and Neck Surgery. 141, 6, p. 566-572 7 p.

Research output: Contribution to journalArticle

Thyroid Nodule
Thyroid Neoplasms
Aptitude
Incidence
Diagnostic Imaging

Management of recurrent/persistent nodal disease in patients with differentiated thyroid cancer: A critical review of the risks and benefits of surgical intervention versus active surveillance

Tufano, R. P., Clayman, G., Heller, K. S., Inabnet, W. B., Kebebew, E., Shaha, A., Steward, D. L. & Tuttle, R. M. Jan 1 2015 In : Thyroid. 25, 1, p. 15-27 13 p.

Research output: Contribution to journalArticle

Thyroid Neoplasms
Consensus
Decision Making
Morbidity
Physicians

Management of recurrent and persistent metastatic lymph nodes in well-differentiated thyroid cancer: A multifactorial decision-making guide for the thyroid cancer care collaborative

Urken, M. L., Milas, M., Randolph, G. W., Tufano, R., Bergman, D., Bernet, V., Brett, E. M., Brierley, J. D., Cobin, R., Doherty, G., Klopper, J., Lee, S., Machac, J., Mechanick, J. I., Orloff, L. A., Ross, D., Smallridge, R. C., Terris, D. J., Clain, J. B. & Tuttle, M. Apr 1 2015 In : Head and Neck. 37, 4, p. 605-614 10 p.

Research output: Contribution to journalArticle

Thyroid Neoplasms
Decision Making
Lymph Nodes
Data Display
Hypoparathyroidism

Recurrent laryngeal nerve safety parameters of the Harmonic Focus during thyroid surgery: Porcine model using continuous monitoring

Wu, C. W., Chai, Y. J. U., Dionigi, G., Chiang, F. Y., Liu, X., Sun, H., Randolph, G. W., Tufano, R. P. & Kim, H. Y. U. Dec 1 2015 In : Laryngoscope. 125, 12, p. 2838-2845 8 p.

Research output: Contribution to journalArticle

Recurrent Laryngeal Nerve
Electromyography
Thyroid Gland
Swine
Safety

Regarding "limiting the risks of radiation exposure in diagnostic imaging"

Aygun, N., Noureldine, S. I. & Tufano, R. P. May 1 2015 In : Surgery. 157, 5, p. 962-963 2 p.

Research output: Contribution to journalArticle

Radiation Dosage
Radiation Protection
Diagnostic Imaging
Radiation Exposure