Ralph H Hruban

Professor

1984 …2020

Research output per year

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Research Output

1423 Pancreaticoduodenectomies for Pancreatic Cancer: A Single-Institution Experience

Winter, J. M., Cameron, J. L., Campbell, K. A., Arnold, M. A., Chang, D. C., Coleman, J. A., Hodgin, M. B., Sauter, P. K., Hruban, R. H., Riall, T. S., Schulick, R. D., Choti, M. A., Lillemoe, K. D. & Yeo, C. J., Nov 1 2006, In : Journal of Gastrointestinal Surgery. 10, 9, p. 1199-1211 13 p.

Research output: Contribution to journalArticle

17β-estradiol inhibits apoptosis of endothelial cells

Alvarez, R. J., Gips, S. J., Moldovan, N., Wilhide, C. C., Milliken, E. E., Hoang, A. T., Hruban, R. H., Silverman, H. S., Dang, C. V. & Goldschmidt-Clermont, P. J., Aug 18 1997, In : Biochemical and Biophysical Research Communications. 237, 2, p. 372-381 10 p.

Research output: Contribution to journalArticle

23Na MRI combined with contrast-enhanced 1H MRI provides in vivo characterization of infarct healing

Hillenbrand, H. B., Becker, L. C., Kharrazian, R., Hu, K., Rochitte, C. E., Kim, R. J., Chen, E. L., Ertl, G., Hruban, R. H. & Lima, J. A. C., Apr 1 2005, In : Magnetic resonance in medicine. 53, 4, p. 843-850 8 p.

Research output: Contribution to journalArticle

2564 resected periampullary adenocarcinomas at a single institution: Trends over three decades

He, J., Ahuja, N., Makary, M. A., Cameron, J. L., Eckhauser, F. E., Choti, M. A., Hruban, R. H., Pawlik, T. M. & Wolfgang, C. L., Jan 2014, In : HPB. 16, 1, p. 83-90 8 p.

Research output: Contribution to journalArticle

Abdominal Lymphangiomas in Adults

Allen, J. G., Riall, T. S., Cameron, J. L., Askin, F. B., Hruban, R. H. & Campbell, K. A., May 1 2006, In : Journal of Gastrointestinal Surgery. 10, 5, p. 746-751 6 p.

Research output: Contribution to journalArticle

Abdominal schwannomas: review of imaging findings and pathology

Lee, N. J., Hruban, R. H. & Fishman, E. K., Mar 6 2017, (Accepted/In press) In : Abdominal Radiology. p. 1-7 7 p.

Research output: Contribution to journalArticle

Aberrant CpG island methylation in cancer cell lines arises in the primary cancers from which they were derived

Ueki, T., Walter, K. M., Skinner, H., Jaffee, E., Hruban, R. H. & Goggins, M., May 21 2002, In : Oncogene. 21, 13, p. 2114-2117 4 p.

Research output: Contribution to journalArticle

Open Access

Aberrant Hypermethylation Tumor Suppressor Genes in Pancreatic Endocrine Neoplasms

House, M. G., Herman, J. G., Guo, M. Z., Hooker, C. M., Schulick, R. D., Lillemoe, K. D., Cameron, J. L., Hruban, R. H., Maitra, A., Yeo, C. J., Eberlein, T. J. & Pitt, H. A., Sep 1 2003, In : Annals of surgery. 238, 3, p. 423-432 10 p.

Research output: Contribution to journalArticle

Aberrant methylation of CpG islands in intraductal papillary mucinous neoplasms of the pancreas

Sato, N., Ueki, T., Fukushima, N., IacobuzioDonahue, C. A., Yeo, C. J., Cameron, J. L., Hruban, R. H. & Goggins, M., Jan 1 2002, In : Gastroenterology. 123, 1, p. 365-372 8 p.

Research output: Contribution to journalArticle

Aberrant methylation of preproenkephalin and p16 genes in pancreatic intraepithelial neoplasia and pancreatic ductal adenocarcinoma

Fukushima, N., Sato, N., Ueki, T., Rosty, C., Walter, K. M., Wilentz, R. E., Yeo, C. J., Hruban, R. H. & Goggins, M., Jan 1 2002, In : American Journal of Pathology. 160, 5, p. 1573-1581 9 p.

Research output: Contribution to journalArticle

Aberrant methylation of suppressor of cytokine signalling-1 (SOCS-1) gene in pancreatic ductal neoplasms

Fukushima, N., Sato, N., Sahin, F., Su, G. H., Hruban, R. H. & Goggins, M., Jul 21 2003, In : British journal of cancer. 89, 2, p. 338-343 6 p.

Research output: Contribution to journalArticle

Aberrant methylation of the 5′ CpG island of TSLC1 is common in pancreatic ductal adenocarcinoma and is first manifest in high-grade PanINs

Jansen, M., Fukushima, N., Rosty, C., Walter, K., Altink, R., Van Heek, T., Hruban, R., Offerhaus, J. G. & Goggins, M., Jan 1 2002, In : Cancer Biology and Therapy. 1, 3, p. 293-296 4 p.

Research output: Contribution to journalArticle

Open Access

Aberrant microRNA-155 expression is an early event in the multistep progression of pancreatic adenocarcinoma

Ryu, J. K., Hong, S. M., Karikari, C. A., Hruban, R. H., Goggins, M. G. & Maitra, A., Apr 2010, In : Pancreatology. 10, 1, p. 66-73 8 p.

Research output: Contribution to journalArticle

Abnormal air-filled spaces in the lung.

Kuhlman, J. E., Reyes, B. L., Hruban, R. H., Askin, F. B., Zerhouni, E. A., Fishman, E. K. & Siegelman, S. S., Jan 1993, In : Radiographics : a review publication of the Radiological Society of North America, Inc. 13, 1, p. 47-75 29 p.

Research output: Contribution to journalArticle

Abrogation of the Rb/p16 tumor-suppressive pathway in virtually all pancreatic carcinomas

Schutte, M., Hruban, R. H., Geradts, J., Maynard, R., Hilgers, W., Rabindran, S. K., Moskaluk, C. A., Hahn, S. A., Schwarte-Waldhoff, I., Schmiegel, W., Baylin, S. B., Kern, S. E. & Herman, J. G., Sep 2 1997, In : Cancer Research. 57, 15, p. 3126-3130 5 p.

Research output: Contribution to journalArticle

Absence of deleterious palladin mutations in patients with familial pancreatic cancer

Klein, A. P., Borges, M., Griffith, M., Brune, K., Hong, S. M., Omura, N., Hruban, R. H. & Goggins, M., Apr 1 2009, In : Cancer Epidemiology Biomarkers and Prevention. 18, 4, p. 1328-1330 3 p.

Research output: Contribution to journalArticle

Absence of E-cadherin expression distinguishes noncohesive from cohesive pancreatic cancer

Winter, J. M., Ting, A. H., Vilardell, F., Gallmeier, E., Baylin, S. B., Hruban, R. H., Kern, S. E. & Iacobuzio-Donahue, C. A., Jan 15 2008, In : Clinical Cancer Research. 14, 2, p. 412-418 7 p.

Research output: Contribution to journalArticle

Absence of germline BRCA1 mutations in familial pancreatic cancer patients

Axilbund, J. E., Argani, P., Kamiyama, M., Palmisano, E., Raben, M., Borges, M., Brune, K. A., Goggins, M., Hruban, R. H. & Klein, A. P., Jan 2009, In : Cancer Biology and Therapy. 8, 2, p. 131-135 5 p.

Research output: Contribution to journalArticle

Open Access

Absorbable suture improves growth of venous anastomoses

Gillinov, A. M., Lee, A. W., Redmond, J. M., Zehr, K. J., Jackson, L., Davis, E. A., Hruban, R. H., Williams, G. M. & Cameron, D. E., Nov 1992, In : Journal of vascular surgery. 16, 5, p. 769-773 5 p.

Research output: Contribution to journalArticle

Accelerated arteriosclerosis in heart transplant recipients: An immunopathology study of 22 transplanted hearts

Hruban, R. H., Beschorner, W. E., Baumgartner, W. A., Augustine, S. M., Reitz, B. A. & Hutchins, G. M., Jan 1 1991, In : Transplantation proceedings. 23, 1 II, p. 1230-1232 3 p.

Research output: Contribution to journalArticle

Accelerated arteriosclerosis in heart transplant recipients is associated with a T-lymphocyte-mediated endothelialitis

Hruban, R. H., Beschorner, W. E., Baumgartner, W. A., Augustine, S. M., Ren, H., Reitz, B. A. & Hutchins, G. M., Jan 1 1990, In : American Journal of Pathology. 137, 4, p. 871-882 12 p.

Research output: Contribution to journalArticle

Accelerated graft arteriosclerosis in cardiac transplants

Qian, Z., Hu, W., Liu, J., Sanfilippo, F., Hruban, R. H. & Baldwin, W. M., Sep 15 2001, In : Transplantation. 72, 5, p. 900-906 7 p.

Research output: Contribution to journalArticle

Accuracy of apparent diffusion coefficient in differentiating pancreatic neuroendocrine tumour from intrapancreatic accessory spleen

Pandey, A., Pandey, P., Ghasabeh, M. A., Varzaneh, F. N., Khoshpouri, P., Shao, N., Pour, M. Z., Fouladi, D. F., Hruban, R. H., O'Broin-Lennon, A. M. & Kamel, I. R., Nov 13 2017, (Accepted/In press) In : European Radiology. p. 1-8 8 p.

Research output: Contribution to journalArticle

Acinar cell carcinoma of the pancreas: Clinical and cytomorphologic characteristics

Toll, A. D., Hruban, R. H. & Ali, S. Z., Jun 26 2013, In : Korean Journal of Pathology. 47, 2, p. 93-99 7 p.

Research output: Contribution to journalReview article

Acinar cell carcinoma with prominent intraductal growth pattern: Case report and review of the literature

Toll, A. D., Mitchell, D., Yeo, C. J., Hruban, R. H. & Witkiewicz, A. K., Dec 1 2011, In : International journal of surgical pathology. 19, 6, p. 795-799 5 p.

Research output: Contribution to journalReview article

Acinar cell cystadenoma of the pancreas a benign neoplasm or non-neoplastic ballooning of acinar and ductal epithelium?

Singhi, A. D., Norwood, S., Liu, T. C., Sharma, R., Wolfgang, C. L., Schulick, R. D., Zeh, H. J. & Hruban, R. H., Sep 1 2013, In : American Journal of Surgical Pathology. 37, 9, p. 1329-1335 7 p.

Research output: Contribution to journalArticle

Acinar cells contribute to the molecular heterogeneity of pancreatic intraepithelial neoplasia

Zhu, L., Shi, G., Schmidt, C. M., Hruban, R. H. & Konieczny, S. F., Jul 2007, In : American Journal of Pathology. 171, 1, p. 263-273 11 p.

Research output: Contribution to journalArticle

A "clearer" View of Pancreatic Pathology: A Review of Tissue Clearing and Advanced Microscopy Techniques

Hong, S. M., Noë, M., Hruban, C. A., Thompson, E., Wood, L. D. & Hruban, R. H., Jan 1 2018, (Accepted/In press) In : Advances in Anatomic Pathology.

Research output: Contribution to journalArticle

A Combination of Molecular Markers and Clinical Features Improve the Classification of Pancreatic Cysts

Springer, S., Wang, Y., Dal Molin, M., Masica, D. L., Jiao, Y., Kinde, I., Blackford, A., Raman, S. P., Wolfgang, C. L., Tomita, T., Niknafs, N., Douville, C., Ptak, J., Dobbyn, L., Allen, P. J., Klimstra, D. S., Schattner, M. A., Schmidt, C. M., Yip-Schneider, M., Cummings, O. W. & 47 others, Brand, R. E., Zeh, H. J., Singhi, A. D., Scarpa, A., Salvia, R., Malleo, G., Zamboni, G., Falconi, M., Jang, J. Y., Kim, S. W., Kwon, W., Hong, S. M., Song, K. B., Kim, S. C., Swan, N., Murphy, J., Geoghegan, J., Brugge, W., Fernandez-Del Castillo, C., Mino-Kenudson, M., Schulick, R., Edil, B. H., Adsay, V., Paulino, J., Van Hooft, J., Yachida, S., Nara, S., Hiraoka, N., Yamao, K., Hijioka, S., Van Der Merwe, S., Goggins, M., Canto, M. I., Ahuja, N., Hirose, K., Makary, M., Weiss, M. J., Cameron, J., Pittman, M., Eshleman, J. R., Diaz, L. A., Papadopoulos, N., Kinzler, K. W., Karchin, R., Hruban, R. H., Vogelstein, B. & Lennon, A. M., Nov 2015, In : Gastroenterology. 149, 6, p. 1501-1510 10 p.

Research output: Contribution to journalArticle

A comparison of flow cytometric and absorption cytometric DNA values as prognostic indicators for pancreatic carcinoma

Bose, K. K., Allison, D. C., Hruban, R. H., Piantadosi, S., Zahurak, M., Dooley, W. C., Lin, P. & Cameron, J. L., Feb 1 1993, In : Cancer. 71, 3, p. 691-700 10 p.

Research output: Contribution to journalArticle

A compendium of potential biomarkers of pancreatic cancer

Harsha, H. C., Kandasamy, K., Ranganathan, P., Rani, S., Ramabadran, S., Gollapudi, S., Balakrishnan, L., Dwivedi, S. B., Telikicherla, D., Selvan, L. D. N., Goel, R., Mathivanan, S., Marimuthu, A., Kashyap, M., Vizza, R. F., Mayer, R. J., DeCaprio, J. A., Srivastava, S., Hanash, S. M., Hruban, R. H. & 1 others, Pandey, A., Apr 1 2009, In : PLoS medicine. 6, 4, e1000046.

Research output: Contribution to journalArticle

Activated epidermal growth factor receptor as a novel target in pancreatic cancer therapy

Harsha, H. C., Jimeno, A., Molina, H., Mlhalas, A. B., Goggins, M. G., Hruban, R. H., Schulick, R. D., Kamath, U., Maitra, A., Hidalgo, M. & Pandey, A., Nov 1 2008, In : Journal of proteome research. 7, 11, p. 4651-4658 8 p.

Research output: Contribution to journalArticle

Acute myelofibrosis. Immunohistochemical study of four cases and comparison with acute megakaryocytic leukemia

Hruban, R. H., Kuhajda, F. P. & Mann, R. B., Jan 1 1987, In : American journal of clinical pathology. 88, 5, p. 578-588 11 p.

Research output: Contribution to journalArticle

Acute pulmonary hemorrhage CT evaluation

Marasco, W. J., Fishman, E. K., Kuhlman, J. E. & Hruban, R. H., Jan 1 1993, In : Clinical Imaging. 17, 1, p. 77-80 4 p.

Research output: Contribution to journalArticle

ACVR1B (ALK4, activin receptor type 1B) gene mutations in pancreatic carcinoma

Su, G. H., Bansal, R., Murphy, K. M., Montgomery, E., Yeo, C. J., Hruban, R. H. & Kern, S. E., Mar 13 2001, In : Proceedings of the National Academy of Sciences of the United States of America. 98, 6, p. 3254-3257 4 p.

Research output: Contribution to journalArticle

Added value of apparent diffusion coefficient in distinguishing between serous and mucin-producing pancreatic cystic neoplasms

Pandey, P., Pandey, A., Shao, N., Varzaneh, F. N., Ghasabeh, M. A., Zharghampour, M., Khoshpouri, P., Fouladi, D., Eng, J., O'Broin-Lennon, A. M., Canto, M., Hruban, R. H. & Kamel, I. R., Jan 1 2019, In : European Radiology.

Research output: Contribution to journalArticle

Adenocarcinoma of the ampulla of Vater: A 28-year experience

Talamini, M. A., Moesinger, R. C., Pitt, H. A., Sohn, T. A., Hruban, R. H., Lillemoe, K. D., Yeo, C. J. & Cameron, J. L., Dec 1 1997, In : Annals of surgery. 225, 5, p. 590-600 11 p.

Research output: Contribution to journalArticle

Adenocarcinoma of the Duodenum: Factors Influencing Long-Term Survival

Sohn, T. A., Lillemoe, K. D., Cameron, J. L., Pitt, H. A., Kaufman, H. S., Hruban, R. H. & Yeo, C. J., Jan 1 1998, In : Journal of Gastrointestinal Surgery. 2, 1, p. 79-87 9 p.

Research output: Contribution to journalArticle

Adenocarcinoma of the hepatopancreatic ampulla in a domestic cat

Haines, V. L., Brown, P. R., Hruban, R. H. & Huso, D. L., Jul 1996, In : Veterinary pathology. 33, 4, p. 439-441 3 p.

Research output: Contribution to journalArticle

Adenocarcinoma of the pancreas

Hruban, R. H. & Klimstra, D. S., Nov 1 2014, In : Seminars in Diagnostic Pathology. 31, 6, p. 443-451 9 p.

Research output: Contribution to journalArticle

Adenocarcinoma of the pancreas: Factors influencing outcome after pancreaticoduodenectomy - The Johns Hopkins experience

Yeo, C. J., Hruban, R. H., Kern, S. E., Abrams, R. A., Gkochow, L. B., Griffin, C. A. & Cameron, J. L., Dec 1 1994, In : Cancer Bulletin. 46, 6, p. 504-510 7 p.

Research output: Contribution to journalReview article

Adenosquamous carcinoma of the pancreas harbors KRAS2, DPC4 and TP53 molecular alterations similar to pancreatic ductal adenocarcinoma

Brody, J. R., Costantino, C. L., Potoczek, M., Cozzitorto, J., McCue, P., Yeo, C. J., Hruban, R. H. & Witkiewicz, A. K., May 1 2009, In : Modern Pathology. 22, 5, p. 651-659 9 p.

Research output: Contribution to journalArticle

Adjuvant chemoradiation therapy for adenocarcinoma of the distal pancreas

Redmond, K. J., Wolfgang, C. L., Sugar, E. A., Ahn, J., Nathan, H., Laheru, D., Edil, B. H., Choti, M. A., Pawlik, T. M., Hruban, R. H., Cameron, J. L. & Herman, J. M., Dec 1 2010, In : Annals of Surgical Oncology. 17, 12, p. 3112-3119 8 p.

Research output: Contribution to journalArticle

Adjuvant Chemoradiotherapy After Pancreatic Resection for Invasive Carcinoma Associated With Intraductal Papillary Mucinous Neoplasm of the Pancreas

Swartz, M. J., Hsu, C. C., Pawlik, T. M., Winter, J., Hruban, R. H., Guler, M., Schulick, R. D., Cameron, J. L., Laheru, D. A., Wolfgang, C. L. & Herman, J. M., Mar 1 2010, In : International Journal of Radiation Oncology Biology Physics. 76, 3, p. 839-844 6 p.

Research output: Contribution to journalArticle

Adjuvant Concurrent Chemoradiation for Adenocarcinoma of the Distal Common Bile Duct

Hughes, M. A., Frassica, D. A., Yeo, C. J., Riall, T. S., Lillemoe, K. D., Cameron, J. L., Donehower, R. C., Laheru, D. A., Hruban, R. H. & Abrams, R. A., May 1 2007, In : International Journal of Radiation Oncology Biology Physics. 68, 1, p. 178-182 5 p.

Research output: Contribution to journalArticle

Adjuvant concurrent chemoradiation for node-positive adenocarcinoma of the duodenum

Swartz, M. J., Hughes, M. A., Frassica, D. A., Herman, J., Yeo, C. J., Riall, T. S., Lillemoe, K. D., Cameron, J. L., Donehower, R. C., Laheru, D. A., Hruban, R. H. & Abrams, R. A., Mar 1 2007, In : Archives of surgery. 142, 3, p. 285-288 4 p.

Research output: Contribution to journalArticle

A draft map of the human proteome

Kim, M. S., Pinto, S. M., Getnet, D., Nirujogi, R. S., Manda, S. S., Chaerkady, R., Madugundu, A. K., Kelkar, D. S., Isserlin, R., Jain, S., Thomas, J. K., Muthusamy, B., Leal-Rojas, P., Kumar, P., Sahasrabuddhe, N. A., Balakrishnan, L., Advani, J., George, B., Renuse, S., Selvan, L. D. N. & 52 others, Patil, A. H., Nanjappa, V., Radhakrishnan, A., Prasad, S., Subbannayya, T., Raju, R., Kumar, M., Sreenivasamurthy, S. K., Marimuthu, A., Sathe, G. J., Chavan, S., Datta, K. K., Subbannayya, Y., Sahu, A., Yelamanchi, S. D., Jayaram, S., Rajagopalan, P., Sharma, J., Murthy, K. R., Syed, N., Goel, R., Khan, A. A., Ahmad, S., Dey, G., Mudgal, K., Chatterjee, A., Huang, T. C., Zhong, J., Wu, X., Shaw, P. G., Freed, D., Zahari, M. S., Mukherjee, K. K., Shankar, S., Mahadevan, A., Lam, H., Mitchell, C. J., Shankar, S. K., Satishchandra, P., Schroeder, J. T., Sirdeshmukh, R., Maitra, A., Leach, S. D., Drake, C. G., Halushka, M. K., Prasad, T. S. K., Hruban, R. H., Kerr, C. L., Bader, G. D., Iacobuzio-Donahue, C. A., Gowda, H. & Pandey, A., Jan 1 2014, In : Nature. 509, 7502, p. 575-581 7 p.

Research output: Contribution to journalArticle

Adult pancreatic hemangioma: Case report and literature review

Mundinger, G. S., Gust, S., Micchelli, S. T., Fishman, E. K., Hruban, R. H. & Wolfgang, C. L., Dec 1 2009, In : Gastroenterology Research and Practice. 839730.

Research output: Contribution to journalArticle

Advancements in pancreatic neuroendocrine tumors

Sadaria, M. R., Hruban, R. H. & Edil, B. H., Sep 4 2013, In : Expert Review of Gastroenterology and Hepatology. 7, 5, p. 477-490 14 p.

Research output: Contribution to journalReview article