Rachel Green

2024

B. subtilis MutS2 splits stalled ribosomes into subunits without mRNA cleavage

Park, E. N., Mackens-Kiani, T., Berhane, R., Esser, H., Erdenebat, C., Burroughs, A. M., Berninghausen, O., Aravind, L., Beckmann, R., Green, R. & Buskirk, A. R., Feb 15 2024, In: EMBO Journal. 43, 4, p. 484-506 23 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2023

Bursting translation on single mRNAs in live cells

Livingston, N. M., Kwon, J., Valera, O., Saba, J. A., Sinha, N. K., Reddy, P., Nelson, B., Wolfe, C., Ha, T., Green, R., Liu, J. & Wu, B., Jul 6 2023, In: Molecular cell. 83, 13, p. 2276-2289.e11

Research output: Contribution to journal › Article › peer-review

Open Access

RNF14-dependent atypical ubiquitylation promotes translation-coupled resolution of RNA-protein crosslinks

Zhao, S., Cordes, J., Caban, K. M., Götz, M. J., Mackens-Kiani, T., Veltri, A. J., Sinha, N. K., Weickert, P., Kaya, S., Hewitt, G., Nedialkova, D. D., Fröhlich, T., Beckmann, R., Buskirk, A. R., Green, R. & Stingele, J., Dec 7 2023, In: Molecular cell. 83, 23, p. 4290-4303.e9

Research output: Contribution to journal › Article › peer-review

Open Access

Saving ribosomal proteins for later

Black, J. J. & Green, R., Nov 2023, In: Nature cell biology. 25, 11, p. 1568-1569 2 p.

Research output: Contribution to journal › Article › peer-review

Structural characterization of mRNA-tRNA translocation intermediates

Agirrezabala, X., Liao, H. Y., Schreiner, E., Fu, J., Ortiz-Meoz, R. F., Schulten, K., Green, R. & Frank, J., Oct 6 2023, Novel Developments in Cryo-EM of Biological Molecules: Resolution in Time and State Space. Taylor and Francis, p. 87-107 21 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

The Myxobacterial Antibiotic Myxovalargin: Biosynthesis, Structural Revision, Total Synthesis, and Molecular Characterization of Ribosomal Inhibition

Koller, T. O., Scheid, U., Kösel, T., Herrmann, J., Krug, D., Boshoff, H. I. M., Beckert, B., Evans, J. C., Schlemmer, J., Sloan, B., Weiner, D. M., Via, L. E., Moosa, A., Ioerger, T. R., Graf, M., Zinshteyn, B., Abdelshahid, M., Nguyen, F., Arenz, S., Gille, F., & 13 othersSiebke, M., Seedorf, T., Plettenburg, O., Green, R., Warnke, A. L., Ullrich, J., Warrass, R., Barry, C. E., Warner, D. F., Mizrahi, V., Kirschning, A., Wilson, D. N. & Müller, R., Jan 18 2023, In: Journal of the American Chemical Society. 145, 2, p. 851-863 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2022

Distinct elongation stalls during translation are linked with distinct pathways for mRNA degradation

Veltri, A. J., D'orazio, K. N., Lessen, L. N., Loll-Krippleber, R., Brown, G. W. & Green, R., Jul 2022, In: eLife. 11, e76038.

Research output: Contribution to journal › Article › peer-review

Open Access

Evolutionarily conserved inhibitory uORFs sensitize Hox mRNA translation to start codon selection stringency

Ivanov, I. P., Saba, J. A., Fan, C. M., Wang, J., Firth, A. E., Cao, C., Green, R. & Dever, T. E., Mar 1 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 9, e2117226119.

Research output: Contribution to journal › Article › peer-review

Open Access

Ribosome collisions induce mRNA cleavage and ribosome rescue in bacteria

Saito, K., Kratzat, H., Campbell, A., Buschauer, R., Burroughs, A. M., Berninghausen, O., Aravind, L., Green, R., Beckmann, R. & Buskirk, A. R., Mar 17 2022, In: Nature. 603, 7901, p. 503-508 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2021

A small molecule that induces translational readthrough of CFTR nonsense mutations by eRF1 depletion

Sharma, J., Du, M., Wong, E., Mutyam, V., Li, Y., Chen, J., Wangen, J., Thrasher, K., Fu, L., Peng, N., Tang, L., Liu, K., Mathew, B., Bostwick, R. J., Augelli-Szafran, C. E., Bihler, H., Liang, F., Mahiou, J., Saltz, J., Rab, A., & 10 othersHong, J., Sorscher, E. J., Mendenhall, E. M., Coppola, C. J., Keeling, K. M., Green, R., Mense, M., Suto, M. J., Rowe, S. M. & Bedwell, D. M., Dec 1 2021, In: Nature communications. 12, 1, 4358.

Research output: Contribution to journal › Article › peer-review

Open Access

Live-cell imaging reveals kinetic determinants of quality control triggered by ribosome stalling

Goldman, D. H., Livingston, N. M., Movsik, J., Wu, B. & Green, R., Apr 15 2021, In: Molecular cell. 81, 8, p. 1830-1840.e8

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Mechanisms that ensure speed and fidelity in eukaryotic translation termination

Lawson, M. R., Lessen, L. N., Wang, J., Prabhakar, A., Corsepius, N. C., Green, R. & Puglisi, J. D., Aug 20 2021, In: Science. 373, 6557, p. 876-882 7 p.

Research output: Contribution to journal › Article › peer-review

Ribosome states signal RNA quality control

D'Orazio, K. N. & Green, R., Apr 1 2021, In: Molecular cell. 81, 7, p. 1372-1383 12 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

Translational control of stem cell function

Saba, J. A., Liakath-Ali, K., Green, R. & Watt, F. M., Oct 2021, In: Nature Reviews Molecular Cell Biology. 22, 10, p. 671-690 20 p.

Research output: Contribution to journal › Review article › peer-review

Translational repression of NMD targets by GIGYF2 and EIF4E2

Zinshteyn, B., Sinha, N. K., Enam, S. U., Koleske, B. & Green, R., Oct 19 2021, In: PLoS genetics. 17, 10 October, e1009813.

Research output: Contribution to journal › Article › peer-review

Open Access

Yeast translation elongation factor eEF3 promotes late stages of tRNA translocation

Ranjan, N., Pochopien, A. A., Chih-Chien Wu, C., Beckert, B., Blanchet, S., Green, R., V Rodnina, M. & Wilson, D. N., Mar 15 2021, In: EMBO Journal. 40, 6, e106449.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

2020

Bifunctional nitrone-conjugated secondary metabolite targeting the ribosome

Bachmann, B. O., Wilson, D. N., Limbrick, E. M., Graf, M., Derewacz, D. K., Nguyen, F., Spraggins, J. M., Wieland, M., Ynigez-Gutierrez, A. E., Reisman, B. J., Zinshteyn, B., McCulloch, K. M., Iverson, T. M. & Green, R., Oct 28 2020, In: Journal of the American Chemical Society. 142, 43, p. 18369-18377 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

EDF1 coordinates cellular responses to ribosome collisions

Sinha, N. K., Ordureau, A., Best, K. M., Saba, J. A., Zinshteyn, B., Sundaramoorthy, E., Fulzele, A., Garshott, D. M., Denk, T., Thoms, M., Paulo, J. A., Harper, J. W., Bennett, E. J., Beckmann, R. & Green, R., Aug 2020, In: eLife. 9, p. 1-84 84 p., e58828.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Scopus citations

GIGYF2 and 4EHP Inhibit Translation Initiation of Defective Messenger RNAs to Assist Ribosome-Associated Quality Control

Hickey, K. L., Dickson, K., Cogan, J. Z., Replogle, J. M., Schoof, M., D'Orazio, K. N., Sinha, N. K., Hussmann, J. A., Jost, M., Frost, A., Green, R., Weissman, J. S. & Kostova, K. K., Sep 17 2020, In: Molecular cell. 79, 6, p. 950-962.e6

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Make or break: the ribosome as a regulator of mRNA decay

Veltri, A. J., D’Orazio, K. N. & Green, R., Mar 1 2020, In: Cell Research. 30, 3, p. 195-196 2 p.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

Molecular mechanism of translational stalling by inhibitory codon combinations and poly(A) tracts

Tesina, P., Lessen, L. N., Buschauer, R., Cheng, J., Wu, C. C. C., Berninghausen, O., Buskirk, A. R., Becker, T., Beckmann, R. & Green, R., Feb 3 2020, In: EMBO Journal. 39, 3, e103365.

Research output: Contribution to journal › Article › peer-review

Open Access

29 Scopus citations

Nuclease-mediated depletion biases in ribosome footprint profiling libraries

Zinshteyn, B., Wangen, J. R., Boyang, H. U. A. & Green, R., Oct 2020, In: RNA. 26, 10, p. 1481-1488 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Puromycin reactivity does not accurately localize translation at the subcellular level

Enam, S. U., Zinshteyn, B., Goldman, D. H., Cassani, M., Livingston, N. M., Seydoux, G. & Green, R., Aug 2020, In: eLife. 9, p. 1-34 34 p., e60303.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

Ribosome Collisions Trigger General Stress Responses to Regulate Cell Fate

Wu, C. C. C., Peterson, A., Zinshteyn, B., Regot, S. & Green, R., Jul 23 2020, In: Cell. 182, 2, p. 404-416.e14

Research output: Contribution to journal › Article › peer-review

Open Access

21 Scopus citations

Ribosome recycling is not critical for translational coupling in E. Coli

Saito, K., Green, R. & Buskirk, A. R., Sep 2020, In: eLife. 9, p. 1-37 37 p., e59974.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Stop codon context influences genome-wide stimulation of termination codon readthrough by aminoglycosides

Wangen, J. R. & Green, R., Jan 2020, In: eLife. 9, e52611.

Research output: Contribution to journal › Article › peer-review

Open Access

27 Scopus citations

Translational initiation in E. Coli occurs at the correct sites genome-wide in the absence of mrna-rrna base-pairing

Saito, K., Green, R. & Buskirk, A. R., Feb 2020, In: eLife. 9, e55002.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

2019

Assaying RNA structure with LASER-Seq

Zinshteyn, B., Chan, D., England, W., Feng, C., Green, R. & Spitale, R. C., Jan 10 2019, In: Nucleic acids research. 47, 1, p. 43-55 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

17 Scopus citations

A systematically-revised ribosome profiling method for bacteria reveals pauses at single-codon resolution

Mohammad, F., Green, R. & Buskirk, A. R., Feb 2019, In: eLife. 8, e42591.

Research output: Contribution to journal › Article › peer-review

Open Access

35 Scopus citations

High-Resolution Ribosome Profiling Defines Discrete Ribosome Elongation States and Translational Regulation during Cellular Stress

Wu, C. C. C., Zinshteyn, B., Wehner, K. A. & Green, R., Mar 7 2019, In: Molecular cell. 73, 5, p. 959-970.e5

Research output: Contribution to journal › Article › peer-review

Open Access

67 Scopus citations

Ribosome queuing enables non-AUG translation to be resistant to multiple protein synthesis inhibitors

Kearse, M. G., Goldman, D. H., Choi, J., Nwaezeapu, C., Liang, D., Green, K. M., Goldstrohm, A. C., Todd, P. K., Green, R. & Wilusz, J. E., Jul 2019, In: Genes and Development. 33, 13-14, p. 871-885 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

The endonuclease cue2 cleaves mRNAs at stalled ribosomes during no go decay

D’Orazio, K. N., Wu, C. C. C., Sinha, N., Loll-Krippleber, R., Brown, G. W. & Green, R., Jun 2019, In: eLife. 8, e49117.

Research output: Contribution to journal › Article › peer-review

Open Access

51 Scopus citations

2018

An evolutionarily conserved ribosome-rescue pathway maintains epidermal homeostasis

Liakath-Ali, K., Mills, E. W., Sequeira, I., Lichtenberger, B. M., Pisco, A. O., Sipilä, K. H., Mishra, A., Yoshikawa, H., Wu, C. C. C., Ly, T., Lamond, A. I., Adham, I. M., Green, R. & Watt, F. M., Apr 19 2018, In: Nature. 556, 7701, p. 376-380 5 p.

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Directed hydroxyl radical probing reveals Upf1 binding to the 80S ribosomal e site rRNA at the L1 stalk

Schuller, A. P., Zinshteyn, B., Enam, S. U. & Green, R., Feb 28 2018, In: Nucleic acids research. 46, 4, p. 2060-2073 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

Roadblocks and resolutions in eukaryotic translation

Schuller, A. P. & Green, R., Aug 1 2018, In: Nature Reviews Molecular Cell Biology. 19, 8, p. 526-541 16 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

67 Scopus citations

Translation elongation and recoding in eukaryotes

Dever, T. E., Dinman, J. D. & Green, R., Aug 1 2018, In: Cold Spring Harbor Perspectives in Biology. 10, 8, a032649.

Research output: Contribution to journal › Article › peer-review

Open Access

46 Scopus citations

2017

Can multidrug-resistant candida auris be reliably identified in clinical microbiology laboratories?

Mizusawa, M., Miller, H., Green, R., Lee, R., Durante, M., Perkins, R., Hewitt, C., Simner, P. J., Carroll, K. C., Hayden, R. T. & Zhang, S. X., Feb 2017, In: Journal of clinical microbiology. 55, 2, p. 638-640 3 p.

Research output: Contribution to journal › Short survey › peer-review

Open Access

127 Scopus citations

Corrigendum: Rapid generation of hypomorphic mutations

Arthur, L. L., Chung, J. J., Janakirama, P., Keefer, K. M., Kolotilin, I., Pavlovic-Djuranovic, S., Chalker, D. L., Grbic, V., Green, R., Menassa, R., True, H. L., Skeath, J. B. & Djuranovic, S., Feb 16 2017, In: Nature communications. 8, p. 14705 1 p., 14705.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

eIF5A Functions Globally in Translation Elongation and Termination

Schuller, A. P., Wu, C. C. C., Dever, T. E., Buskirk, A. R. & Green, R., Apr 20 2017, In: Molecular cell. 66, 2, p. 194-205.e5

Research output: Contribution to journal › Article › peer-review

Open Access

142 Scopus citations

Inhibition of Eukaryotic Translation by the Antitumor Natural Product Agelastatin A

McClary, B., Zinshteyn, B., Meyer, M., Jouanneau, M., Pellegrino, S., Yusupova, G., Schuller, A., Reyes, J. C. P., Lu, J., Guo, Z., Ayinde, S., Luo, C., Dang, Y., Romo, D., Yusupov, M., Green, R. & Liu, J. O., May 18 2017, In: Cell Chemical Biology. 24, 5, p. 605-613.e5

Research output: Contribution to journal › Article › peer-review

Open Access

25 Scopus citations

Not just Salk

Greider, C., Hopkins, N., Steitz, J., Amon, A., Asai, D., Barres, B., Bass, B., Bassler, B., Birgeneau, R., Bjorkman, P., Botchan, M., Brugge, J., Cech, T., Colwell, R., Craig, N., Delange, T., Eisen, M., Gottesman, S., Green, R., Handelsman, J., & 17 othersKimble, J., King, M. C., Lehmann, R., Marder, E., Mullins, D., O’Shea, E., Schmid, S., Seydoux, G., Spradling, A., Storz, G., Szostak, J., Telesnitsky, A., Tilghman, S., Tjian, R., Vale, R., Wolberger, C. & Zakian, V., Sep 15 2017, In: Science. 357, 6356, p. 1105-1106 2 p.

Research output: Contribution to journal › Letter › peer-review

1 Scopus citations

Precision genome editing using synthesis-dependent repair of Cas9-induced DNA breaks

Paix, A., Folkmann, A., Goldman, D. H., Kulaga, H., Grzelak, M. J., Rasoloson, D., Paidemarry, S., Green, R., Reed, R. R. & Seydoux, G., Dec 12 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 50, p. E10745-E10754

Research output: Contribution to journal › Article › peer-review

Open Access

65 Scopus citations

Rapid generation of hypomorphic mutations

Arthur, L. L., Chung, J. J., Jankirama, P., Keefer, K. M., Kolotilin, I., Pavlovic-Djuranovic, S., Chalker, D. L., Grbic, V., Green, R., Menassa, R., True, H. L., Skeath, J. B. & Djuranovic, S., Jan 20 2017, In: Nature communications. 8, 14112.

Research output: Contribution to journal › Article › peer-review

Open Access