Philip Chun Wong


1990 …2018
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Amyloid Precursor Protein Secretases Medicine & Life Sciences
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Motor Neurons Medicine & Life Sciences
Amyotrophic Lateral Sclerosis Medicine & Life Sciences
Mutation Medicine & Life Sciences
Intermediate Filaments Medicine & Life Sciences

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Research Output 1990 2018

Reversible induction of TDP-43 granules in cortical neurons after traumatic injury

Wiesner, D., Tar, L., Linkus, B., Chandrasekar, A., olde Heuvel, F., Dupuis, L., Tsao, W., Wong, P. C., Ludolph, A. & Roselli, F., Jan 1 2018, In : Experimental Neurology. 299, p. 15-25 11 p.

Research output: Contribution to journalArticle

Amyotrophic Lateral Sclerosis
Wounds and Injuries
Stab Wounds

An LHX1-Regulated Transcriptional Network Controls Sleep/Wake Coupling and Thermal Resistance of the Central Circadian Clockworks

Bedont, J. L., LeGates, T. A., Buhr, E., Bathini, A., Ling, J. P., Bell, B., Wu, M. N., Wong, P. C., Van Gelder, R. N., Mongrain, V., Hattar, S. & Blackshaw, S., Jan 9 2017, In : Current Biology. 27, 1, p. 128-136 9 p.

Research output: Contribution to journalArticle

vasoactive intestinal peptide
Suprachiasmatic Nucleus
Gene Regulatory Networks
Vasoactive Intestinal Peptide

Challenges and advances in gene therapy approaches for neurodegenerative disorders

Donde, A., Wong, P. C. & Chen, L. L., Jun 1 2017, In : Current Gene Therapy. 17, 3, p. 187-193 7 p.

Research output: Contribution to journalReview article

Antisense Oligonucleotides
Neurodegenerative Diseases
Genetic Therapy
Spinal Muscular Atrophy
United States Food and Drug Administration

Cryptic exon incorporation occurs in Alzheimer’s brain lacking TDP-43 inclusion but exhibiting nuclear clearance of TDP-43

Sun, M., Bell, W., LaClair, K. D., Ling, J. P., Han, H., Kageyama, Y., Pletnikova, O., Troncoso, J. C., Wong, P. C. & Chen, L. L., Mar 22 2017, (Accepted/In press) In : Acta Neuropathologica. p. 1-9 9 p.

Research output: Contribution to journalArticle

Intranuclear Inclusion Bodies
Alzheimer Disease
TDP-43 Proteinopathies

Tdp-43 cryptic exons are highly variable between cell types

Jeong, Y. H., Ling, J. P., Lin, S. Z., Donde, A. N., Braunstein, K. E., Majounie, E., Traynor, B. J., LaClair, K. D., Lloyd, T. E. & Wong, P. C., Feb 2 2017, In : Molecular Neurodegeneration. 12, 1, 13.

Research output: Contribution to journalArticle

TDP-43 Proteinopathies
Inclusion Body Myositis
Skeletal Muscle Fibers