Philip Chun Wong

Professor

1990 …2018
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Research Output 1990 2018

Reversible induction of TDP-43 granules in cortical neurons after traumatic injury

Wiesner, D., Tar, L., Linkus, B., Chandrasekar, A., olde Heuvel, F., Dupuis, L., Tsao, W., Wong, P. C., Ludolph, A. & Roselli, F. Jan 1 2018 In : Experimental Neurology. 299, p. 15-25 11 p.

Research output: Contribution to journalArticle

Amyotrophic Lateral Sclerosis
Neurons
Wounds and Injuries
Pathology
Stab Wounds

An LHX1-Regulated Transcriptional Network Controls Sleep/Wake Coupling and Thermal Resistance of the Central Circadian Clockworks

Bedont, J. L., LeGates, T. A., Buhr, E., Bathini, A., Ling, J. P., Bell, B., Wu, M. N., Wong, P. C., Van Gelder, R. N., Mongrain, V., Hattar, S. & Blackshaw, S. Jan 9 2017 In : Current Biology. 27, 1, p. 128-136 9 p.

Research output: Contribution to journalArticle

vasoactive intestinal peptide
Suprachiasmatic Nucleus
Gene Regulatory Networks
Vasoactive Intestinal Peptide
sleep

Challenges and advances in gene therapy approaches for neurodegenerative disorders

Donde, A., Wong, P. C. & Chen, L. L. Jun 1 2017 In : Current Gene Therapy. 17, 3, p. 187-193 7 p.

Research output: Contribution to journalReview article

Antisense Oligonucleotides
Neurodegenerative Diseases
Genetic Therapy
Spinal Muscular Atrophy
United States Food and Drug Administration

Cryptic exon incorporation occurs in Alzheimer’s brain lacking TDP-43 inclusion but exhibiting nuclear clearance of TDP-43

Sun, M., Bell, W., LaClair, K. D., Ling, J. P., Han, H., Kageyama, Y., Pletnikova, O., Troncoso, J. C., Wong, P. C. & Chen, L. L. Mar 22 2017 (Accepted/In press) In : Acta Neuropathologica. p. 1-9 9 p.

Research output: Contribution to journalArticle

Intranuclear Inclusion Bodies
Exons
Alzheimer Disease
Brain
TDP-43 Proteinopathies

Tdp-43 cryptic exons are highly variable between cell types

Jeong, Y. H., Ling, J. P., Lin, S. Z., Donde, A. N., Braunstein, K. E., Majounie, E., Traynor, B. J., LaClair, K. D., Lloyd, T. E. & Wong, P. C. Feb 2 2017 In : Molecular Neurodegeneration. 12, 1, 13

Research output: Contribution to journalArticle

Exons
TDP-43 Proteinopathies
Inclusion Body Myositis
Neurons
Skeletal Muscle Fibers