Peter V Johnston

Assistant Professor

1984 …2019
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Research Output 1984 2019

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Article
2019

Intravascular Stem Cell Bioreactor for Prevention of Adverse Remodeling After Myocardial Infarction

Johnston, P. V., Hwang, C-W., Bogdan, V., Mills, K. J., Eggan, E. R., Leszczynska, A., Wu, K. C-C., Herzka, D., Brinker, J. A., Schulman, S. P., Banerjee, M., Florea, V., Natsumeda, M., Tompkins, B., Balkan, W., Hare, J. M., Tomaselli, G. F., Weiss, R. G. & Gerstenblith, G., Aug 6 2019, In : Journal of the American Heart Association. 8, 15, p. e012351

Research output: Contribution to journalArticle

Open Access
Bioreactors
Stem Cells
Myocardial Infarction
Placebos
Stroke Volume
2018

Molecular Imaging of CXCL12 Promoter-driven HSV1-TK Reporter Gene Expression

Alon, L., Kraitchman, D., Schar, M., Cortez, A., Yadav, N. N., Krimins, R., Johnston, P. V., Mcmahon, M. T., Van Zijl, P. C., Nimmagadda, S., Pomper, M. G., Bulte, J. W. & Gilad, A. A., Mar 1 2018, In : Biotechnology and Bioprocess Engineering. 23, 2, p. 208-217 10 p.

Research output: Contribution to journalArticle

Molecular imaging
Molecular Imaging
Reporter Genes
Gene expression
Magnetic resonance imaging

Not All Stem Cells Are Created Equal

Johnston, P. V., Duckers, H. J., Raval, A. N., Cook, T. D. & Pepine, C. J., Sep 28 2018, In : Circulation Research. 123, 8, p. 944-946 3 p.

Research output: Contribution to journalArticle

Bone Marrow Cells
Regeneration
Stem Cells
Heart Failure
Clinical Trials

The CardiAMP Heart Failure trial: A randomized controlled pivotal trial of high-dose autologous bone marrow mononuclear cells using the CardiAMP cell therapy system in patients with post–myocardial infarction heart failure: Trial rationale and study design

Raval, A. N., Cook, T. D., Duckers, H. J., Johnston, P. V., Traverse, J. H., Abraham, W. T., Altman, P. A. & Pepine, C. J., Jul 1 2018, In : American Heart Journal. 201, p. 141-148 8 p.

Research output: Contribution to journalArticle

Cell- and Tissue-Based Therapy
Bone Marrow Cells
Infarction
Randomized Controlled Trials
Heart Failure
2016
Photoplethysmography
Valsalva Maneuver
Ventricular Pressure
Fingers
Blood Pressure
2015

Stem cell impregnated nanofiber stent sleeve for on-stent production and intravascular delivery of paracrine factors

Hwang, C-W., Johnston, P. V., Gerstenblith, G., Weiss, R. G., Tomaselli, G. F., Bogdan, V. E., Panigrahi, A., Leszczynska, A. & Xia, Z., 2015, In : Biomaterials. 52, 1, p. 318-326 9 p.

Research output: Contribution to journalArticle

Nanofibers
Stents
Stem cells
Stem Cells
Mesenchymal Stromal Cells
2014

Does transendocardial injection of mesenchymal stem cells improve myocardial function locally or globally? An analysis from the percutaneous stem cell injection delivery effects on neomyogenesis (POSEIDON) randomized trial

Suncion, V. Y., Ghersin, E., Fishman, J. E., Zambrano, J. P., Karantalis, V., Mandel, N., Nelson, K. H., Gerstenblith, G., Difede Velazquez, D. L., Breton, E., Sitammagari, K., Schulman, I. H., Taldone, S. N., Williams, A. R., Sanina, C., Johnston, P. V., Brinker, J. A., Altman, P., Mushtaq, M., Trachtenberg, B. & 8 others, Mendizabal, A. M., Tracy, M., Da Silva, J., McNiece, I. K., Lardo, A. C., George, R. T., Hare, J. M. & Heldman, A. W., 2014, In : Circulation Research. 114, 8, p. 1292-1301 10 p.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Stem Cells
Injections
Cicatrix
Cardiomyopathies
Mesenchymal Stromal Cells
Capsules
Swine
X-Rays
Magnetic Resonance Imaging

Intracoronary cardiosphere-derived cells after myocardial infarction: Evidence of therapeutic regeneration in the final 1-year results of the CADUCEUS trial (CArdiosphere-derived aUtologous stem CElls to reverse ventricular dysfunction)

Malliaras, K., Makkar, R. R., Smith, R. R., Cheng, K., Wu, E., Bonow, R. O., Marbán, L., Mendizabal, A., Cingolani, E., Johnston, P. V., Gerstenblith, G., Schuleri, K. H., Lardo, A. C. & Marbán, E., Jan 21 2014, In : Journal of the American College of Cardiology. 63, 2, p. 110-122 13 p.

Research output: Contribution to journalArticle

Ventricular Dysfunction
Regeneration
Stem Cells
Cicatrix
Myocardial Infarction
2012

Comparison of allogeneic vs autologous bone marrow-derived mesenchymal stem cells delivered by transendocardial injection in patients with ischemic cardiomyopathy: The POSEIDON randomized trial

Hare, J. M., Fishman, J. E., Gerstenblith, G., DiFede Velazquez, D. L., Zambrano, J. P., Suncion, V. Y., Tracy, M., Ghersin, E., Johnston, P. V., Brinker, J. A., Breton, E., Davis Sproul, J., Schulman, I. H., Byrnes, J., Mendizabal, A. M., Lowery, M. H., Rouy, D., Altman, P., Wong Po Foo, C., Ruiz, P. & 4 others, Amador, A., Da Silva, J., McNiece, I. K. & Heldman, A. W., Dec 12 2012, In : Journal of the American Medical Association. 308, 22, p. 2369-2379 11 p.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Cardiomyopathies
Bone Marrow
Injections
Heart Failure
Photoplethysmography
Valsalva Maneuver
Ventricular Pressure
Fingers
Pulse

Intracoronary cardiosphere-derived cells for heart regeneration after myocardial infarction (CADUCEUS): A prospective, randomised phase 1 trial

Makkar, R. R., Smith, R. R., Cheng, K., Malliaras, K., Thomson, L. E. J., Berman, D., Czer, L. S. C., Marbán, L., Mendizabal, A., Johnston, P. V., Russell, S. D., Schuleri, K. H., Lardo, A. C., Gerstenblith, G. & Marbán, E., Mar 2012, In : The Lancet. 379, 9819, p. 895-904 10 p.

Research output: Contribution to journalArticle

Regeneration
Myocardial Infarction
Stroke Volume
Cicatrix
Heart Neoplasms
2011

Subacute stent thrombosis owing to complete clopidogrel resistance successfully managed with prasugrel

Flaherty, M. P., Johnston, P. V. & Rade, J. J., Jul 2011, In : Journal of Invasive Cardiology. 23, 7, p. 300-304 5 p.

Research output: Contribution to journalArticle

clopidogrel
Stents
Thrombosis
Arteries
Purinergic P1 Receptors
2009

Engraftment, differentiation, and functional benefits of autologous cardiosphere-derived cells in porcine ischemic cardiomyopathy

Johnston, P. V., Sasano, T., Mills, K., Evers, R., Lee, S. T., Smith, R. R., Lardo, A. C., Lai, S., Steenbergen, C. J., Gerstenblith, G., Lange, R. & Marbán, E., Sep 2009, In : Circulation. 120, 12, p. 1075-1083 9 p.

Research output: Contribution to journalArticle

Cardiomyopathies
Swine
Infarction
Nitroglycerin
Left Ventricular Dysfunction

Kidney-derived stromal cells modulate dendritic and T cell responses

Huang, Y., Johnston, P. V., Zhang, B., Zakari, A., Chowdhry, T., Smith, R. R., Marbán, E., Rabb, H. & Womer, K. L., Apr 2009, In : Journal of the American Society of Nephrology. 20, 4, p. 831-841 11 p.

Research output: Contribution to journalArticle

Stromal Cells
Dendritic Cells
T-Lymphocytes
Kidney
Cell Lineage
2007

Beyond Low-Density Lipoprotein Cholesterol. Defining the Role of Low-Density Lipoprotein Heterogeneity in Coronary Artery Disease

Mudd, J. O., Borlaug, B. A., Johnston, P. V., Kral, B. G., Rouf, R., Blumenthal, R. S. & Kwiterovich, P. O., Oct 30 2007, In : Journal of the American College of Cardiology. 50, 18, p. 1735-1741 7 p.

Research output: Contribution to journalArticle

LDL Lipoproteins
LDL Cholesterol
Apolipoproteins B
Coronary Artery Disease
Particle Size
2004

Mycotic aortocoronary saphenous vein graft aneurysm presenting with unstable angina pectoris

Hirsch, G. A., Johnston, P. V., Conte, J. V. & Achuff, S. C., Oct 2004, In : Annals of Thoracic Surgery. 78, 4, p. 1456-1458 3 p.

Research output: Contribution to journalArticle

Unstable Angina
Saphenous Vein
Aneurysm
Infected Aneurysm
Transplants
1999

Tedisamil in a chronic canine model of atrial flutter

Fischbach, P. S., Johnston, P. V., Friedrichs, G. S. & Lucchesi, B. R., Aug 1999, In : Journal of Cardiovascular Pharmacology. 34, 2, p. 212-218 7 p.

Research output: Contribution to journalArticle

Atrial Flutter
Canidae
Dogs
Potassium Channels
tedisamil
1997

Scatter factor/hepatocyte growth factor expression enhances human glioblastoma tumorigenicity and growth

Laterra, J. J., Rosen, E., Nam, M., Ranganathan, S., Fielding, K. & Johnston, P. V., Jun 27 1997, In : Biochemical and Biophysical Research Communications. 235, 3, p. 743-747 5 p.

Research output: Contribution to journalArticle

Hepatocyte Growth Factor
Glioblastoma
Growth
Gene transfer
Heterografts

Scatter factor/hepatocyte growth factor gene transfer enhances glioma growth and angiogenesis in vivo

Laterra, J. J., Nam, M., Rosen, E., Rao, J. S., Lamszus, K., Goldberg, I. D. & Johnston, P. V., Apr 1997, In : Laboratory Investigation. 76, 4, p. 565-577 13 p.

Research output: Contribution to journalArticle

Hepatocyte Growth Factor
Glioma
Growth
Genes
Proto-Oncogene Proteins c-met
1996

Delivery of human fibroblast growth factor-1 gene to brain by modified rat brain endothelial cells

Johnston, P. V., Nam, M., Hossain, M. A., Indurti, R. R., Mankowski, J. L., Wilson, M. A. A. & Laterra, J. J., Oct 1996, In : Journal of Neurochemistry. 67, 4, p. 1643-1652 10 p.

Research output: Contribution to journalArticle

Fibroblast Growth Factor 1
Fibroblast Growth Factors
Endothelial cells
Rats
Brain

Endothelial cell-based cytokine gene delivery inhibits 9L glioma growth in vivo

Nam, M., Johnston, P. V., Lal, B., Indurti, R., Wilson, M. A. A. & Laterra, J. J., Aug 26 1996, In : Brain Research. 731, 1-2, p. 161-170 10 p.

Research output: Contribution to journalArticle

Glioma
Endothelial Cells
Cytokines
Interleukin-2
Growth

Scatter factor enhances glioma malignancy

Nam, M. J., Johnston, P. V., Rosen, E. M. & Laterra, J. J., 1996, In : FASEB Journal. 10, 3

Research output: Contribution to journalArticle

Hepatocyte Growth Factor
Glioma
Neoplasms
cells
Proto-Oncogene Proteins c-met
1985

Alteration in membrane fluidity of cerebral capillary endothelial cells (CEC) by chronic dietary fat manipulation

Brown, M. L., Johnston, P. V., Schwartz, H. M. & Lange, D. G., 1985, In : Federation proceedings. 44, 6

Research output: Contribution to journalArticle

Membrane Fluidity
Dietary Fats
Endothelial Cells
1984
Dietary Fats
Adenosine
Endothelial Cells