Peter Zandi

2024

Patterns of pharmacotherapy for bipolar disorder: A GBC survey

Singh, B., Yocum, A. K., Strawbridge, R., Burdick, K. E., Millett, C. E., Peters, A. T., Sperry, S. H., Fico, G., Vieta, E., Verdolini, N., Godin, O., Leboyer, M., Etain, B., Tso, I. F., Coombes, B. J., McInnis, M. G., Nierenberg, A. A., Young, A. H., Ashton, M. M., Berk, M., & 13 othersWilliams, L. J., Keramatian, K., Yatham, L. N., Overs, B. J., Fullerton, J. M., Roberts, G., Mitchell, P. B., Andreassen, O. A., Andreazza, A. C., Zandi, P. P., Pham, D., Biernacka, J. M. & Frye, M. A., Feb 2024, In: Bipolar Disorders. 26, 1, p. 22-32 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

The Human Phenotype Ontology in 2024: phenotypes around the world

Gargano, M. A., Matentzoglu, N., Coleman, B., Addo-Lartey, E. B., Anagnostopoulos, A. V., Anderton, J., Avillach, P., Bagley, A. M., Bakštein, E., Balhoff, J. P., Baynam, G., Bello, S. M., Berk, M., Bertram, H., Bishop, S., Blau, H., Bodenstein, D. F., Botas, P., Boztug, K., Čady, J., & 156 othersCallahan, T. J., Cameron, R., Carbon, S. J., Castellanos, F., Caufield, J. H., Chan, L. E., Chute, C. G., Cruz-Rojo, J., Dahan-Oliel, N., Davids, J. R., Dieuleveult, M., Souza, V., de Vries, B. B. A., Vries, E., DePaulo, J. R., Derfalvi, B., Dhombres, F., Diaz-Byrd, C., Dingemans, A. J. M., Donadille, B., Duyzend, M., Elfeky, R., Essaid, S., Fabrizzi, C., Fico, G., Firth, H. V., Freudenberg-Hua, Y., Fullerton, J. M., Gabriel, D. L., Gilmour, K., Giordano, J., Goes, F. S., Moses, R. G., Green, I., Griese, M., Groza, T., Gu, W., Guthrie, J., Gyori, B., Hamosh, A., Hanauer, M., Hanušová, K., He, Y., Hegde, H., Helbig, I., Holasová, K., Hoyt, C. T., Huang, S., Hurwitz, E., Jacobsen, J. O. B., Jiang, X., Joseph, L., Keramatian, K., King, B., Knoflach, K., Koolen, D. A., Kraus, M. L., Kroll, C., Kusters, M., Ladewig, M. S., Lagorce, D., Lai, M. C., Lapunzina, P., Laraway, B., Lewis-Smith, D., Li, X., Lucano, C., Majd, M., Marazita, M. L., Martinez-Glez, V., McHenry, T. H., McInnis, M. G., McMurry, J. A., Mihulová, M., Millett, C. E., Mitchell, P. B., Moslerová, V., Narutomi, K., Nematollahi, S., Nevado, J., Nierenberg, A. A., Čajbiková, N. N., Nurnberger, J. I., Ogishima, S., Olson, D., Ortiz, A., Pachajoa, H., Nanclares, G. P., Peters, A., Putman, T., Rapp, C. K., Rath, A., Reese, J., Rekerle, L., Roberts, A. M., Roy, S., Sanders, S. J., Schuetz, C., Schulte, E. C., Schulze, T. G., Schwarz, M., Scott, K., Seelow, D., Seitz, B., Shen, Y., Similuk, M. N., Simon, E. S., Singh, B., Smedley, D., Smith, C. L., Smolinsky, J. T., Sperry, S., Stafford, E., Stefancsik, R., Steinhaus, R., Strawbridge, R., Sundaramurthi, J. C., Talapova, P., Castano, J. A. T., Tesner, P., Thomas, R. H., Thurm, A., Turnovec, M., van Gijn, M. E., Vasilevsky, N. A., Vlčková, M., Walden, A., Wang, K., Wapner, R., Ware, J. S., Wiafe, A. A., Wiafe, S. A., Wiggins, L. D., Williams, A. E., Wu, C., Wyrwoll, M. J., Xiong, H., Yalin, N., Yamamoto, Y., Yatham, L. N., Yocum, A. K., Young, A. H., Yüksel, Z., Zandi, P. P., Zankl, A., Zarante, I., Zvolský, M., Toro, S., Carmody, L. C., Harris, N. L., Munoz-Torres, M. C., Danis, D., Mungall, C. J., Köhler, S., Haendel, M. A. & Robinson, P. N., Jan 5 2024, In: Nucleic acids research. 52, D1, p. D1333-D1346

Research output: Contribution to journal › Article › peer-review

Open Access

Trends in Telepsychiatry and In-Person Psychiatric Care for Depression in an Academic Health System, 2017-2022

Ettman, C. K., Brantner, C. L., Albert, M., Goes, F. S., Mojtabai, R., Spivak, S., Stuart, E. A. & Zandi, P., Feb 1 2024, In: Psychiatric services (Washington, D.C.). 75, 2, p. 178-181 4 p.

Research output: Contribution to journal › Article › peer-review

2023

Association of polygenic score and the involvement of cholinergic and glutamatergic pathways with lithium treatment response in patients with bipolar disorder

Amare, A. T., Thalamuthu, A., Schubert, K. O., Fullerton, J. M., Ahmed, M., Hartmann, S., Papiol, S., Heilbronner, U., Degenhardt, F., Tekola-Ayele, F., Hou, L., Hsu, Y. H., Shekhtman, T., Adli, M., Akula, N., Akiyama, K., Ardau, R., Arias, B., Aubry, J. M., Hasler, R., & 146 othersRichard-Lepouriel, H., Perroud, N., Backlund, L., Bhattacharjee, A. K., Bellivier, F., Benabarre, A., Bengesser, S., Biernacka, J. M., Birner, A., Marie-Claire, C., Cervantes, P., Chen, H. C., Chillotti, C., Cichon, S., Cruceanu, C., Czerski, P. M., Dalkner, N., Del Zompo, M., DePaulo, J. R., Étain, B., Jamain, S., Falkai, P., Forstner, A. J., Frisen, L., Frye, M. A., Gard, S., Garnham, J. S., Goes, F. S., Grigoroiu-Serbanescu, M., Fallgatter, A. J., Stegmaier, S., Ethofer, T., Biere, S., Petrova, K., Schuster, C., Adorjan, K., Budde, M., Heilbronner, M., Kalman, J. L., Kohshour, M. O., Reich-Erkelenz, D., Schaupp, S. K., Schulte, E. C., Senner, F., Vogl, T., Anghelescu, I. G., Arolt, V., Dannlowski, U., Dietrich, D., Figge, C., Jäger, M., Lang, F. U., Juckel, G., Konrad, C., Reimer, J., Schmauß, M., Schmitt, A., Spitzer, C., von Hagen, M., Wiltfang, J., Zimmermann, J., Andlauer, T. F. M., Fischer, A., Bermpohl, F., Ritter, P., Matura, S., Gryaznova, A., Falkenberg, I., Yildiz, C., Kircher, T., Schmidt, J., Koch, M., Gade, K., Trost, S., Haussleiter, I. S., Lambert, M., Rohenkohl, A. C., Kraft, V., Grof, P., Hashimoto, R., Hauser, J., Herms, S., Hoffmann, P., Jiménez, E., Kahn, J. P., Kassem, L., Kuo, P. H., Kato, T., Kelsoe, J., Kittel-Schneider, S., Ferensztajn-Rochowiak, E., König, B., Kusumi, I., Laje, G., Landén, M., Lavebratt, C., Leboyer, M., Leckband, S. G., Tortorella, A., Manchia, M., Martinsson, L., McCarthy, M. J., McElroy, S., Colom, F., Millischer, V., Mitjans, M., Mondimore, F. M., Monteleone, P., Nievergelt, C. M., Nöthen, M. M., Novák, T., O’Donovan, C., Ozaki, N., Pfennig, A., Pisanu, C., Potash, J. B., Reif, A., Reininghaus, E., Rouleau, G. A., Rybakowski, J. K., Schalling, M., Schofield, P. R., Schweizer, B. W., Severino, G., Shilling, P. D., Shimoda, K., Simhandl, C., Slaney, C. M., Squassina, A., Stamm, T., Stopkova, P., Maj, M., Turecki, G., Vieta, E., Veeh, J., Witt, S. H., Wright, A., Zandi, P. P., Mitchell, P. B., Bauer, M., Alda, M., Rietschel, M., McMahon, F. J., Schulze, T. G., Clark, S. R. & Baune, B. T., 2023, (Accepted/In press) In: Molecular psychiatry.

Research output: Contribution to journal › Article › peer-review

Open Access

Classifying and clustering mood disorder patients using smartphone data from a feasibility study

Langholm, C., Breitinger, S., Gray, L., Goes, F., Walker, A., Xiong, A., Stopel, C., Zandi, P., Frye, M. A. & Torous, J., Dec 2023, In: npj Digital Medicine. 6, 1, 238.

Research output: Contribution to journal › Article › peer-review

Open Access

Contributions of circadian clock genes to cell survival in fibroblast models of lithium-responsive bipolar disorder

Mishra, H. K., Wei, H., Rohr, K. E., Ko, I., Nievergelt, C. M., Maihofer, A. X., Shilling, P. D., Alda, M., Berrettini, W. H., Brennand, K. J., Calabrese, J. R., Coryell, W. H., Frye, M., Gage, F., Gershon, E., McInnis, M. G., Nurnberger, J., Oedegaard, K. J., Zandi, P. P., Kelsoe, J. R., & 1 othersMcCarthy, M. J., Sep 2023, In: European Neuropsychopharmacology. 74, p. 1-14 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Corrigendum to “The PHQ-9 item 9 based screening for suicide risk: A validation study of the patient health questionnaire (PHQ)-9 item 9 with the Columbia suicide severity rating scale (C-SSRS)” [J. Affect. Disord. 232 (2018) 34–40, (S0165032717309655), (10.1016/j.jad.2018.02.045)]

Na, P. J., Yaramala, S. R., Kim, J. A., Kim, H., Goes, F. S., Zandi, P. P., Vande Voort, J. L., Sutor, B., Croarkin, P. E. & Bobo, W. V., Feb 15 2023, In: Journal of Affective Disorders. 323, p. 900 1 p.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

Determinants of experience & satisfaction in telehealth psychiatry during the COVID-19 pandemic for patients & providers

Morreale, M., Cohen, I., Van Wert, M., Beccera, A., Miller, L., Narrow, W., Schweizer, B., Straub, J., Zandi, P. & Ruble, A., 2023, In: Frontiers in Psychiatry. 14, 1237249.

Research output: Contribution to journal › Article › peer-review

Open Access

Digital Phenotyping for Mood Disorders: Methodology-Oriented Pilot Feasibility Study

Breitinger, S., Gardea-Resendez, M., Langholm, C., Xiong, A., Laivell, J., Stoppel, C., Harper, L., Volety, R., Walker, A., D'Mello, R., Byun, A. J. S., Zandi, P., Goes, F. S., Frye, M. & Torous, J., Dec 29 2023, In: Journal of medical Internet research. 25, p. e47006

Research output: Contribution to journal › Article › peer-review

Open Access

Focal adhesion is associated with lithium response in bipolar disorder: evidence from a network-based multi-omics analysis

Niemsiri, V., Rosenthal, S. B., Nievergelt, C. M., Maihofer, A. X., Marchetto, M. C., Santos, R., Shekhtman, T., Alliey-Rodriguez, N., Anand, A., Balaraman, Y., Berrettini, W. H., Bertram, H., Burdick, K. E., Calabrese, J. R., Calkin, C. V., Conroy, C., Coryell, W. H., DeModena, A., Eyler, L. T., Feeder, S., & 35 othersFisher, C., Frazier, N., Frye, M. A., Gao, K., Garnham, J., Gershon, E. S., Goes, F. S., Goto, T., Harrington, G. J., Jakobsen, P., Kamali, M., Kelly, M., Leckband, S. G., Lohoff, F. W., McCarthy, M. J., McInnis, M. G., Craig, D., Millett, C. E., Mondimore, F., Morken, G., Nurnberger, J. I., Donovan, C. O., Øedegaard, K. J., Ryan, K., Schinagle, M., Shilling, P. D., Slaney, C., Stapp, E. K., Stautland, A., Tarwater, B., Zandi, P. P., Alda, M., Fisch, K. M., Gage, F. H. & Kelsoe, J. R., 2023, (Accepted/In press) In: Molecular psychiatry.

Research output: Contribution to journal › Article › peer-review

Open Access

Genome-wide significant risk loci for mood disorders in the Old Order Amish founder population

Humphries, E. M., Ahn, K., Kember, R. L., Lopes, F. L., Mocci, E., Peralta, J. M., Blangero, J., Glahn, D. C., Goes, F. S., Zandi, P. P., Kochunov, P., Van Hout, C., Shuldiner, A. R., Pollin, T. I., Mitchell, B. D., Bucan, M., Hong, L. E., McMahon, F. J. & Ament, S. A., 2023, (Accepted/In press) In: Molecular psychiatry.

Research output: Contribution to journal › Article › peer-review

Open Access

The miR-124-AMPAR pathway connects polygenic risks with behavioral changes shared between schizophrenia and bipolar disorder

Namkung, H., Yukitake, H., Fukudome, D., Lee, B. J., Tian, M., Ursini, G., Saito, A., Lam, S., Kannan, S., Srivastava, R., Niwa, M., Sharma, K., Zandi, P., Jaaro-Peled, H., Ishizuka, K., Chatterjee, N., Huganir, R. L. & Sawa, A., Jan 18 2023, In: Neuron. 111, 2, p. 220-235.e9

Research output: Contribution to journal › Article › peer-review

Open Access

The prevalence of mental health disorders in people with HIV and the effects on the HIV care continuum

North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD) of the International Epidemiologic Databases to Evaluate AIDS (IeDEA), Feb 1 2023, In: AIDS. 37, 2, p. 259-269 11 p.

Research output: Contribution to journal › Article › peer-review

Translating clinical notes into quantitative measures—a real-world observation on the response to cholinesterase inhibitors or selective serotonin reuptake inhibitors prescribed to outpatients with dementia using electronic medical records

Chotiyanonta, J. S., Onda, K., Nowrangi, M. A., Li, X., Xu, X., Adams, R., Lyketsos, C. G., Zandi, P. & Oishi, K., 2023, In: Frontiers in Pharmacology. 14, 1177026.

Research output: Contribution to journal › Article › peer-review

Open Access

2022

Amygdala and anterior cingulate transcriptomes from individuals with bipolar disorder reveal downregulated neuroimmune and synaptic pathways

Zandi, P. P., Jaffe, A. E., Goes, F. S., Burke, E. E., Collado-Torres, L., Huuki-Myers, L., Seyedian, A., Lin, Y., Seifuddin, F., Pirooznia, M., Ross, C. A., Kleinman, J. E., Weinberger, D. R. & Hyde, T. M., Mar 2022, In: Nature neuroscience. 25, 3, p. 381-389 9 p.

Research output: Contribution to journal › Article › peer-review

Correction: Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patients (Translational Psychiatry, (2021), 11, 1, (606), 10.1038/s41398-021-01702-2)

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Dec 2022, In: Translational psychiatry. 12, 1, 278.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

Correction of depression-associated circadian rhythm abnormalities is associated with lithium response in bipolar disorder

Federoff, M., McCarthy, M. J., Anand, A., Berrettini, W. H., Bertram, H., Bhattacharjee, A., Calkin, C. V., Conroy, C., Coryell, WH., D'Arcangelo, N., DeModena, A., Fisher, C., Feeder, S., Frazier, N., Frye, M. A., Gao, K., Garnham, J., Gershon, E. S., Alliey-Rodriguez, N., Glazer, K., & 29 othersGoes, F., Karberg, T., Harrington, G., Jakobsen, P., Kamali, M., Kelly, M., Leckband, S. G., Lohoff, F., Maihofer, A. X., McInnis, MG., Mondimore, F., Morken, G., Nurnberger, J. I., Oedegaard, K. J., Ritchey, M., Ryan, K., Schinagle, M., Schoeyen, H., Schwebel, C., Shaw, M., Shilling, P. D., Slaney, C., Stautland, A., Tarwater, B., Calabrese, J. R., Alda, M., Nievergelt, C. M., Zandi, P. P. & Kelsoe, J. R., Aug 2022, In: Bipolar Disorders. 24, 5, p. 521-529 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Eating Disorders Working Group of the Psychiatric Genomics Consortium, German Borderline Genomics Consortium, MVP Suicide Exemplar Workgroup & VA Million Veteran Program, Feb 1 2022, In: Biological psychiatry. 91, 3, p. 313-327 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Erratum: Using polygenic scores and clinical data for bipolar disorder patient stratification and lithium response prediction: Machine learning approach (The British Journal of Psychiatry (2022) (1–10) DOI: 10.1192/bjp.2022.28)

Cearns, M., Amare, A. T., Schubert, K. O., Thalamuthu, A., Frank, J., Streit, F., Adli, M., Akula, N., Akiyama, K., Ardau, R., Arias, B., Aubry, J. M., Backlund, L., Bhattacharjee, A. K., Bellivier, F., Benabarre, A., Bengesser, S., Biernacka, J. M., Birner, A., Brichant-Petitjean, C., & 97 othersCervantes, P., Chen, H. C., Chillotti, C., Cichon, S., Cruceanu, C., Czerski, P. M., Dalkner, N., Dayer, A., Degenhardt, F., Zompo, M. D., Depaulo, J. R., Étain, B., Falkai, P., Forstner, A. J., Frisen, L., Frye, M. A., Fullerton, J. M., Gard, S., Garnham, J. S., Goes, F. S., Grigoroiu-Serbanescu, M., Grof, P., Hashimoto, R., Hauser, J., Heilbronner, U., Herms, S., Hoffmann, P., Hofmann, A., Hou, L., Hsu, Y. H., Jamain, S., Jiménez, E., Kahn, J. P., Kassem, L., Kuo, P. H., Kato, T., Kelsoe, J., Kittel-Schneider, S., Kliwicki, S., König, B., Kusumi, I., Laje, G., Landén, M., Lavebratt, C., Leboyer, M., Leckband, S. G., Maj, M., Manchia, M., Martinsson, L., McCarthy, M. J., McElroy, S., Colom, F., Mitjans, M., Mondimore, F. M., Monteleone, P., Nievergelt, C. M., Nöthen, M. M., Novák, T., O'Donovan, C., Ozaki, N., Millischer, V., Papiol, S., Pfennig, A., Pisanu, C., Potash, J. B., Reif, A., Reininghaus, E., Rouleau, G. A., Rybakowski, J. K., Schalling, M., Schofield, P. R., Schweizer, B. W., Severino, G., Shekhtman, T., Shilling, P. D., Shimoda, K., Simhandl, C., Slaney, C. M., Squassina, A., Stamm, T., Stopkova, P., Tekolaayele, F., Tortorella, A., Turecki, G., Veeh, J., Vieta, E., Witt, S. H., Roberts, G., Zandi, P. P., Alda, M., Bauer, M., McMahon, F. J., Mitchell, P. B., Schulze, T. G., Rietschel, M., Clark, S. R. & Baune, B. T., Aug 1 2022, In: British Journal of Psychiatry. 221, 2, p. 494 1 p.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

Exome sequencing in bipolar disorder identifies AKAP11 as a risk gene shared with schizophrenia

Palmer, D. S., Howrigan, D. P., Chapman, S. B., Adolfsson, R., Bass, N., Blackwood, D., Boks, M. P. M., Chen, C. Y., Churchhouse, C., Corvin, A. P., Craddock, N., Curtis, D., Di Florio, A., Dickerson, F., Freimer, N. B., Goes, F. S., Jia, X., Jones, I., Jones, L., Jonsson, L., & 27 othersKahn, R. S., Landén, M., Locke, A. E., McIntosh, A. M., McQuillin, A., Morris, D. W., O’Donovan, M. C., Ophoff, R. A., Owen, M. J., Pedersen, N. L., Posthuma, D., Reif, A., Risch, N., Schaefer, C., Scott, L., Singh, T., Smoller, J. W., Solomonson, M., Clair, D. S., Stahl, E. A., Vreeker, A., Walters, J. T. R., Wang, W., Watts, N. A., Yolken, R., Zandi, P. P. & Neale, B. M., May 2022, In: Nature genetics. 54, 5, p. 541-547 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Investigating the phenotypic and genetic associations between personality traits and suicidal behavior across major mental health diagnoses

Consortium on Lithium Genetics (ConLiGen), PsyCourse, Dec 1 2022, In: European Archives of Psychiatry and Clinical Neuroscience. 272, 8, p. 1611-1620 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

PsychENCODE, Psychosis Endophenotypes International Consortium, The SynGO Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium & Indonesia Schizophrenia Consortium, Apr 21 2022, In: Nature. 604, 7906, p. 502-508 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

National Network of Depression Centers' Recommendations on Harmonizing Clinical Documentation of Electroconvulsive Therapy

Zandi, P. P., Morreale, M., Reti, I. M., Maixner, D. F., McDonald, W. M., Patel, P. D., Achtyes, E., Bhati, M. T., Carr, B. R., Conroy, S. K., Cristancho, M., Dubin, M. J., Francis, A., Glazer, K., Ingram, W., Khurshid, K., McClintock, S. M., Pinjari, O. F., Reeves, K., Rodriguez, N. F., & 10 othersSampson, S., Seiner, S. J., Selek, S., Sheline, Y., Smetana, R. W., Soda, T., Trapp, N. T., Wright, J. H., Husain, M. & Weiner, R. D., Sep 1 2022, In: Journal of ECT. 38, 3, p. 159-164 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Rare variants implicate NMDA receptor signaling and cerebellar gene networks in risk for bipolar disorder

Hasin, N., Riggs, L. M., Shekhtman, T., Ashworth, J., Lease, R., Oshone, R. T., Humphries, E. M., Badner, J. A., Thomson, P. A., Glahn, D. C., Craig, D. W., Edenberg, H. J., Gershon, E. S., McMahon, F. J., Nurnberger, J. I., Zandi, P. P., Kelsoe, J. R., Roach, J. C., Gould, T. D. & Ament, S. A., Sep 2022, In: Molecular psychiatry. 27, 9, p. 3842-3856 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders

iPSYCH, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium & Sex Differences Cross-Disorder Analysis Group of the Psychiatric Genomics Consortium, Jan 1 2022, In: Biological psychiatry. 91, 1, p. 102-117 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Standardizing Electronic Health Record Data on AD/ADRD to Accelerate Health Equity in Prevention, Detection, and Treatment

Lyketsos, C. G., Roberts, S. B., Swift, E. K., Quina, A., Moon, G., Kremer, I., Tariot, P., Fillit, H., Bovenkamp, D. E., Zandi, P. P. & Haaga, J. G., Jul 2022, In: The journal of prevention of Alzheimer's disease. 9, 3, p. 556-560 5 p.

Research output: Contribution to journal › Article › peer-review

Using polygenic scores and clinical data for bipolar disorder patient stratification and lithium response prediction: machine learning approach

Cearns, M., Amare, A. T., Schubert, K. O., Thalamuthu, A., Frank, J., Streit, F., Adli, M., Akula, N., Akiyama, K., Ardau, R., Arias, B., Aubry, J. M., Backlund, L., Bhattacharjee, A. K., Bellivier, F., Benabarre, A., Bengesser, S., Biernacka, J. M., Birner, A., Brichant-Petitjean, C., & 97 othersCervantes, P., Chen, H. C., Chillotti, C., Cichon, S., Cruceanu, C., Czerski, P. M., Dalkner, N., Dayer, A., Degenhardt, F., Zompo, M. D., Depaulo, J. R., Étain, B., Falkai, P., Forstner, A. J., Frisen, L., Frye, M. A., Fullerton, J. M., Gard, S., Garnham, J. S., Goes, F. S., Grigoroiu-Serbanescu, M., Grof, P., Hashimoto, R., Hauser, J., Heilbronner, U., Herms, S., Hoffmann, P., Hofmann, A., Hou, L., Hsu, Y. H., Jamain, S., Jiménez, E., Kahn, J. P., Kassem, L., Kuo, P. H., Kato, T., Kelsoe, J., Kittel-Schneider, S., Kliwicki, S., König, B., Kusumi, I., Laje, G., Landén, M., Lavebratt, C., Leboyer, M., Leckband, S. G., Maj, M., Manchia, M., Martinsson, L., McCarthy, M. J., McElroy, S., Colom, F., Mitjans, M., Mondimore, F. M., Monteleone, P., Nievergelt, C. M., Nöthen, M. M., Novák, T., O'Donovan, C., Ozaki, N., Millischer, V., Papiol, S., Pfennig, A., Pisanu, C., Potash, J. B., Reif, A., Reininghaus, E., Rouleau, G. A., Rybakowski, J. K., Schalling, M., Schofield, P. R., Schweizer, B. W., Severino, G., Shekhtman, T., Shilling, P. D., Shimoda, K., Simhandl, C., Slaney, C. M., Squassina, A., Stamm, T., Stopkova, P., Tekola-Ayele, F., Tortorella, A., Turecki, G., Veeh, J., Vieta, E., Witt, S. H., Roberts, G., Zandi, P. P., Alda, M., Bauer, M., McMahon, F. J., Mitchell, P. B., Schulze, T. G., Rietschel, M., Clark, S. R. & Baune, B. T., Apr 9 2022, In: British Journal of Psychiatry. 220, 4, p. 219-228 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2021

A 7 Tesla Amygdalar-Hippocampal Shape Analysis of Lithium Response in Bipolar Disorder

Athey, T. L., Ceritoglu, C., Tward, D. J., Kutten, K. S., DePaulo, J. R., Glazer, K., Goes, F. S., Kelsoe, J. R., Mondimore, F., Nievergelt, C. M., Rootes-Murdy, K., Zandi, P. P., Ratnanather, J. T. & Mahon, P. B., Feb 16 2021, In: Frontiers in Psychiatry. 12, 614010.

Research output: Contribution to journal › Article › peer-review

Open Access

A learning algorithm for predicting mental health symptoms and substance use

Fojo, A. T., Lesko, C. R., Benke, K. S., Chander, G., Lau, B., Moore, R. D., Zandi, P. P. & Zeger, S. L., Feb 2021, In: Journal of Psychiatric Research. 134, p. 22-29 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Association of Attention-Deficit/Hyperactivity Disorder and Depression Polygenic Scores with Lithium Response: A Consortium for Lithium Genetics Study

Coombes, B. J., Millischer, V., Batzler, A., Larrabee, B., Hou, L., Papiol, S., Heilbronner, U., Adli, M., Akiyama, K., Akula, N., Amare, A. T., Ardau, R., Arias, B., Aubry, J. M., Backlund, L., Bauer, M., Baune, B. T., Bellivier, F., Benabarre, A., Bengesser, S., & 88 othersBhattacharjee, A. K., Cervantes, P., Chen, H. C., Chillotti, C., Cichon, S., Clark, S. R., Colom, F., Cruceanu, C., Czerski, P. M., Dalkner, N., Degenhardt, F., Zompo, M. D., Raymond DePaulo, J., Étain, B., Falkai, P., Ferensztajn-Rochowiak, E., Forstner, A. J., Frisen, L., Gard, S., Garnham, J. S., Goes, F. S., Grigoroiu-Serbanescu, M., Grof, P., Hashimoto, R., Hauser, J., Herms, S., Hoffmann, P., Jamain, S., Jiménez, E., Kahn, J. P., Kassem, L., Kato, T., Kelsoed, J. R., Kittel-Schneider, S., König, B., Kuo, P. H., Kusumi, I., Landén, G. L. M., Lavebratt, C., Leboyer, M., Leckband, S. G., Maj, M., Manchia, M., Martinsson, L., McCarthy, M. J., McElroy, S. L., Mitchell, P. B., Mitjans, M., Mondimore, F. M., Monteleone, P., Nievergelt, C. M., Nöthen, M. M., Novák, T., O'Donovan, C., Osby, U., Ozaki, N., Pfennig, A., Pisanu, C., Potash, J. B., Reif, A., Reininghaus, E., Rietschel, M., Rouleau, G. A., Rybakowski, J. K., Schalling, M., Schofield, P. R., Schuberti, K. O., Schweizer, B. W., Severino, G., Shekhtman, T., Shilling, P. D., Shimoda, K., Simhandl, C., Slaney, C. M., Squassina, A., Stamm, T., Stopkova, P., Tortorella, A., Turecki, G., Vieta, E., Witt, S. H., Zandi, P. P., Fullerton, J. M., Alda, M., Frye, M. A., Schulze, T. G., McMahon, F. J. & Biernacka, J. M., Dec 1 2021, In: Complex Psychiatry. 7, 3-4, p. 80-89 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Association of polygenic score for major depression with response to lithium in patients with bipolar disorder

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Jun 1 2021, In: Molecular psychiatry. 26, 6, p. 2457-2470 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium & Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Apr 1 2021, In: Molecular psychiatry. 26, 4, p. 1286-1298 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Characterisation of age and polarity at onset in bipolar disorder

Kalman, J. L., Loohuis, L. M. O., Vreeker, A., McQuillin, A., Stahl, E. A., Ruderfer, D., Grigoroiu-Serbanescu, M., Panagiotaropoulou, G., Ripke, S., Bigdeli, T. B., Stein, F., Meller, T., Meinert, S., Pelin, H., Streit, F., Papiol, S., Adams, M. J., Adolfsson, R., Adorjan, K., Agartz, I., & 153 othersAminoff, S. R., Anderson-Schmidt, H., Andreassen, O. A., Ardau, R., Aubry, J. M., Balaban, C., Bass, N., Baune, B. T., Bellivier, F., Benabarre, A., Bengesser, S., Berrettini, W. H., Boks, M. P., Bromet, E. J., Brosch, K., Budde, M., Byerley, W., Cervantes, P., Chillotti, C., Cichon, S., Clark, S. R., Comes, A. L., Corvin, A., Coryell, W., Craddock, N., Craig, D. W., Croarkin, P. E., Cruceanu, C., Czerski, P. M., Dalkner, N., Dannlowski, U., Degenhardt, F., Del Zompo, M., Depaulo, J. R., Djurovic, S., Edenberg, H. J., Al Eissa, M., Elvsåshagen, T., Etain, B., Fanous, A. H., Fellendorf, F., Fiorentino, A., Forstner, A. J., Frye, M. A., Fullerton, J. M., Gade, K., Garnham, J., Gershon, E., Gill, M., Goes, F. S., Gordon-Smith, K., Grof, P., Guzman-Parra, J., Hahn, T., Hasler, R., Heilbronner, M., Heilbronner, U., Jamain, S., Jimenez, E., Jones, I., Jones, L., Jonsson, L., Kahn, R. S., Kelsoe, J. R., Kennedy, J. L., Kircher, T., Kirov, G., Kittel-Schneider, S., Klöhn-Saghatolislam, F., Knowles, J. A., Kranz, T. M., Lagerberg, T. V., Landen, M., Lawson, W. B., Leboyer, M., Li, Q. S., Maj, M., Malaspina, D., Manchia, M., Mayoral, F., McElroy, S. L., McInnis, M. G., McIntosh, A. M., Medeiros, H., Melle, I., Milanova, V., Mitchell, P. B., Monteleone, P., Monteleone, A. M., Nöthen, M. M., Novak, T., Nurnberger, J. I., O'Brien, N., O'Connell, K. S., O'Donovan, C., O'Donovan, M. C., Opel, N., Ortiz, A., Owen, M. J., Pålsson, E., Pato, C., Pato, M. T., Pawlak, J., Pfarr, J. K., Pisanu, C., Potash, J. B., Rapaport, M. H., Reich-Erkelenz, D., Reif, A., Reininghaus, E., Repple, J., Richard-Lepouriel, H., Rietschel, M., Ringwald, K., Roberts, G., Rouleau, G., Schaupp, S., Scheftner, W. A., Schmitt, S., Schofield, P. R., Schubert, K. O., Schulte, E. C., Schweizer, B., Senner, F., Severino, G., Sharp, S., Slaney, C., Smeland, O. B., Sobell, J. L., Squassina, A., Stopkova, P., Strauss, J., Tortorella, A., Turecki, G., Twarowska-Hauser, J., Veldic, M., Vieta, E., Vincent, J. B., Xu, W., Zai, C. C., Zandi, P. P., Di Florio, A., Smoller, J. W., Biernacka, J. M., McMahon, F. J., Alda, M., Müller-Myhsok, B., Koutsouleris, N., Falkai, P., Freimer, N. B., Andlauer, T. F. M., Schulze, T. G. & Ophoff, R. A., Dec 11 2021, In: British Journal of Psychiatry. 219, 6, p. 659-669 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Circadian rhythms in bipolar disorder patient-derived neurons predict lithium response: preliminary studies

The Pharmacogenomics of Bipolar Disorder Study, Jul 2021, In: Molecular psychiatry. 26, 7, p. 3383-3394 12 p.

Research output: Contribution to journal › Article › peer-review

Clinical predictors of non-response to lithium treatment in the Pharmacogenomics of Bipolar Disorder (PGBD) study

Lin, Y., Maihofer, A. X., Stapp, E., Ritchey, M., Alliey-Rodriguez, N., Anand, A., Balaraman, Y., Berrettini, W. H., Bertram, H., Bhattacharjee, A., Calkin, C. V., Conroy, C., Coryell, W., D'Arcangelo, N., DeModena, A., Biernacka, J. M., Fisher, C., Frazier, N., Frye, M., Gao, K., & 33 othersGarnham, J., Gershon, E., Glazer, K., Goes, F. S., Goto, T., Karberg, E., Harrington, G., Jakobsen, P., Kamali, M., Kelly, M., Leckband, S. G., Lohoff, F. W., Stautland, A., McCarthy, M. J., McInnis, M. G., Mondimore, F., Morken, G., Nurnberger, J. I., Oedegaard, K. J., Syrstad, V. E. G., Ryan, K., Schinagle, M., Schoeyen, H., Andreassen, O. A., Shaw, M., Shilling, P. D., Slaney, C., Tarwater, B., Calabrese, J. R., Alda, M., Nievergelt, C. M., Zandi, P. P. & Kelsoe, J. R., Dec 2021, In: Bipolar Disorders. 23, 8, p. 821-831 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patients

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Dec 2021, In: Translational psychiatry. 11, 1, 606.

Research output: Contribution to journal › Article › peer-review

Open Access

Correction: Investigating rare pathogenic/likely pathogenic exonic variation in bipolar disorder (Molecular Psychiatry, (2021), 26, 9, (5239-5250), 10.1038/s41380-020-01006-9)

Jia, X., Goes, F. S., Locke, A. E., Palmer, D., Wang, W., Cohen-Woods, S., Genovese, G., Jackson, A. U., Jiang, C., Kvale, M., Mullins, N., Nguyen, H., Pirooznia, M., Rivera, M., Ruderfer, D. M., Shen, L., Thai, K., Zawistowski, M., Zhuang, Y., Abecasis, G., & 56 othersAkil, H., Bergen, S., Burmeister, M., Chapman, S., DelaBastide, M., Juréus, A., Kang, H. M., Kwok, P. Y., Li, J. Z., Levy, S. E., Monson, E. T., Moran, J., Sobell, J., Watson, S., Willour, V., Zöllner, S., Adolfsson, R., Blackwood, D., Boehnke, M., Breen, G., Corvin, A., Craddock, N., DiFlorio, A., Hultman, C. M., Landen, M., Lewis, C., McCarroll, S. A., Richard McCombie, W., McGuffin, P., McIntosh, A., McQuillin, A., Morris, D., Myers, R. M., O’Donovan, M., Ophoff, R., Boks, M., Kahn, R., Ouwehand, W., Owen, M., Pato, C., Pato, M., Posthuma, D., Potash, J. B., Reif, A., Sklar, P., Smoller, J., Sullivan, P. F., Vincent, J., Walters, J., Neale, B., Purcell, S., Risch, N., Schaefer, C., Stahl, E. A., Zandi, P. P. & Scott, L. J., Sep 2021, In: Molecular psychiatry. 26, 9, p. 5251 1 p.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

Cross-species Association between Telomere Length and Glucocorticoid Exposure

Lee, R. S., Zandi, P. P., Santos, A., Aulinas, A., Carey, J. L., Webb, S. M., McCaul, M. E., Resmini, E. & Wand, G. S., Dec 1 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 12, p. E5124-E5135

Research output: Contribution to journal › Article › peer-review

Open Access

De novo variation in bipolar disorder

Goes, F. S., Pirooznia, M., Tehan, M., Zandi, P. P., McGrath, J., Wolyniec, P., Nestadt, G. & Pulver, A. E., Aug 2021, In: Molecular psychiatry. 26, 8, p. 4127-4136 10 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Developing Treatments for Alzheimer’s and Related Disorders with Precision Medicine: A Vision

Avramopoulos, D., Kapogiannis, D., Leoutsakos, J. M., Lyketsos, C. G., Mahairaki, V., Nowrangi, M., Oishi, K., Oh, E. S., Rosenberg, P. B., Samus, Q., Smith, G. S., Witwer, K., Yasar, S. & Zandi, P. P., 2021, Advances in Experimental Medicine and Biology. Springer, p. 395-402 8 p. (Advances in Experimental Medicine and Biology; vol. 1339).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

HUNT All-In Psychiatry, Jun 2021, In: Nature genetics. 53, 6, p. 817-829 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

HLA-DRB1 and HLA-DQB1 genetic diversity modulates response to lithium in bipolar affective disorders

Le Clerc, S., Lombardi, L., Baune, B. T., Amare, A. T., Schubert, K. O., Hou, L., Clark, S. R., Papiol, S., Cearns, M., Heilbronner, U., Degenhardt, F., Tekola-Ayele, F., Hsu, Y. H., Shekhtman, T., Adli, M., Akula, N., Akiyama, K., Ardau, R., Arias, B., Aubry, J. M., & 103 othersBacklund, L., Bhattacharjee, A. K., Bellivier, F., Benabarre, A., Bengesser, S., Biernacka, J. M., Birner, A., Brichant-Petitjean, C., Cervantes, P., Chen, H. C., Chillotti, C., Cichon, S., Cruceanu, C., Czerski, P. M., Dalkner, N., Dayer, A., Del Zompo, M., DePaulo, J. R., Étain, B., Jamain, S., Falkai, P., Forstner, A. J., Frisen, L., Frye, M. A., Fullerton, J. M., Gard, S., Garnham, J. S., Goes, F. S., Grigoroiu-Serbanescu, M., Grof, P., Hashimoto, R., Hauser, J., Herms, S., Hoffmann, P., Jiménez, E., Kahn, J. P., Kassem, L., Kuo, P. H., Kato, T., Kelsoe, J. R., Kittel-Schneider, S., Ferensztajn-Rochowiak, E., König, B., Kusumi, I., Laje, G., Landén, M., Lavebratt, C., Leckband, S. G., Tortorella, A., Manchia, M., Martinsson, L., McCarthy, M. J., McElroy, S. L., Colom, F., Millischer, V., Mitjans, M., Mondimore, F. M., Monteleone, P., Nievergelt, C. M., Nöthen, M. M., Novák, T., O’Donovan, C., Ozaki, N., Ösby, U., Pfennig, A., Potash, J. B., Reif, A., Reininghaus, E., Rouleau, G. A., Rybakowski, J. K., Schalling, M., Schofield, P. R., Schweizer, B. W., Severino, G., Shilling, P. D., Shimoda, K., Simhandl, C., Slaney, C. M., Pisanu, C., Squassina, A., Stamm, T., Stopkova, P., Maj, M., Turecki, G., Vieta, E., Veeh, J., Witt, S. H., Wright, A., Zandi, P. P., Mitchell, P. B., Bauer, M., Alda, M., Rietschel, M., McMahon, F. J., Schulze, T. G., Spadoni, J. L., Boukouaci, W., Richard, J. R., Le Corvoisier, P., Barrau, C., Zagury, J. F., Leboyer, M. & Tamouza, R., Dec 2021, In: Scientific reports. 11, 1, 17823.

Research output: Contribution to journal › Article › peer-review

Open Access

Investigating rare pathogenic/likely pathogenic exonic variation in bipolar disorder

Jia, X., Goes, F. S., Locke, A. E., Palmer, D., Wang, W., Cohen-Woods, S., Genovese, G., Jackson, A. U., Jiang, C., Kvale, M., Mullins, N., Nguyen, H., Pirooznia, M., Rivera, M., Ruderfer, D. M., Shen, L., Thai, K., Zawistowski, M., Zhuang, Y., Abecasis, G., & 56 othersAkil, H., Bergen, S., Burmeister, M., Chapman, S., DelaBastide, M., Juréus, A., Kang, H. M., Kwok, P. Y., Li, J. Z., Levy, S. E., Monson, E. T., Moran, J., Sobell, J., Watson, S., Willour, V., Zöllner, S., Adolfsson, R., Blackwood, D., Boehnke, M., Breen, G., Corvin, A., Craddock, N., DiFlorio, A., Hultman, C. M., Landen, M., Lewis, C., McCarroll, S. A., Richard McCombie, W., McGuffin, P., McIntosh, A., McQuillin, A., Morris, D., Myers, R. M., O’Donovan, M., Ophoff, R., Boks, M., Kahn, R., Ouwehand, W., Owen, M., Pato, C., Pato, M., Posthuma, D., Potash, J. B., Reif, A., Sklar, P., Smoller, J., Sullivan, P. F., Vincent, J., Walters, J., Neale, B., Purcell, S., Risch, N., Schaefer, C., Stahl, E. A., Zandi, P. P. & Scott, L. J., Sep 2021, In: Molecular psychiatry. 26, 9, p. 5239-5250 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Methylomic and transcriptomic predictors of one-month exposure to cortisol in healthy individuals

Lee, R. S., Zandi, P. P., Lin, Y., Seifuddin, F., Benke, K. S., McCaul, M. E., Reitz, K. & Wand, G. S., 2021, In: Stress. 24, 6, p. 840-848 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Neuronal and glial 3D chromatin architecture informs the cellular etiology of brain disorders

The PsychENCODE Consortium, Dec 1 2021, In: Nature communications. 12, 1, 3968.

Research output: Contribution to journal › Article › peer-review

Open Access

2020

Defining major depressive disorder cohorts using the EHR: Multiple phenotypes based on ICD-9 codes and medication orders

Ingram, W. M., Baker, A. M., Bauer, C. R., Brown, J. P., Goes, F. S., Larson, S. & Zandi, P. P., Jun 2020, In: Neurology Psychiatry and Brain Research. 36, p. 18-26 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Development of the national network of depression centers mood outcomes program: A multisite platform for measurement-based care

Zandi, P. P., Wang, Y. H., Patel, P. D., Katzelnick, D., Turvey, C. L., Wright, J. H., Ajilore, O., Coryell, W., Schneck, C. D., Guille, C., Saunders, E. F. H., Lazarus, S. A., Cuellar, V. A., Selvaraj, S., Dill Rinvelt, P., Greden, J. F. & Raymond DePaulo, J., May 2020, In: Psychiatric Services. 71, 5, p. 456-464 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

Host–parasite interaction associated with major mental illness

Kano, S. I., Hodgkinson, C. A., Jones-Brando, L., Eastwood, S., Ishizuka, K., Niwa, M., Choi, E. Y., Chang, D. J., Chen, Y., Velivela, S. D., Leister, F., Wood, J., Chowdari, K., Ducci, F., Caycedo, D. A., Heinz, E., Newman, E. R., Cascella, N., Mortensen, P. B., Zandi, P. P., & 6 othersDickerson, F., Nimgaonkar, V., Goldman, D., Harrison, P. J., Yolken, R. H. & Sawa, A., Jan 1 2020, In: Molecular psychiatry. 25, 1, p. 194-205 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

International Consortium on the Genetics of Electroconvulsive Therapy and Severe Depressive Disorders (Gen-ECT-ic)

Soda, T., McLoughlin, D. M., Clark, S. R., Oltedal, L., Kessler, U., Haavik, J., Bousman, C., Smith, D. J., Bioque, M., Clements, C. C., Loo, C., Vila-Rodriguez, F., Minelli, A., Mickey, B. J., Milev, R., Docherty, A. R., Langan Martin, J., Achtyes, E. D., Arolt, V., Redlich, R., & 37 othersDannlowski, U., Cardoner, N., Clare, E., Craddock, N., Di Florio, A., Dmitrzak-Weglarz, M., Forty, L., Gordon-Smith, K., Husain, M., Ingram, W. M., Jones, L., Jones, I., Juruena, M., Kirov, G., Landén, M., Müller, D. J., Nordensköld, A., Pålsson, E., Paul, M., Permoda, A., Pliszka, B., Rea, J., Schubert, K. O., Sonnen, J. A., Soria, V., Stageman, W., Takamiya, A., Urretavizacaya, M., Watson, S., Zavorotny, M., Young, A. H., Vieta, E., Rybakowski, J. K., Gennarelli, M., Zandi, P. P., Sullivan, P. F. & Baune, B. T., Oct 1 2020, In: European Archives of Psychiatry and Clinical Neuroscience. 270, 7, p. 921-932 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

lncRNAKB, a knowledgebase of tissue-specific functional annotation and trait association of long noncoding RNA

Seifuddin, F., Singh, K., Suresh, A., Judy, J. T., Chen, Y. C., Chaitankar, V., Tunc, I., Ruan, X., Li, P., Chen, Y., Cao, H., Lee, R. S., Goes, F. S., Zandi, P. P., Jafri, M. S. & Pirooznia, M., Dec 1 2020, In: Scientific Data. 7, 1, 326.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Peter Zandi

Research output

Search results