Peter Calabresi

Professor

1989 …2020
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Research Output 1989 2020

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Article
1989

Saccade Preparation Inhibits Reorienting to Recently Attended Locations

Rafal, R. D., Calabresi, P., Brennan, C. W. & Sciolto, T. K., Nov 1989, In : Journal of Experimental Psychology: Human Perception and Performance. 15, 4, p. 673-685 13 p.

Research output: Contribution to journalArticle

Saccades
Mesencephalon
Eye Movements
Nervous System
Reaction Time
1993

Progressive spinal multiple sclerosis

Calabresi, P., Giang, D. W. & Goodman, A. D., 1993, In : Seminars in Neurology. 13, 4, p. 322-332 11 p.

Research output: Contribution to journalArticle

Spinal Cord Diseases
Multiple Sclerosis
Differential Diagnosis
1994

An ultrastructural analysis of human post-infectious (allergic) encephalomyelitis

Calabresi, P. & Powers, J. M., May 1994, In : Acta Neuropathologica. 87, 5, p. 541-544 4 p.

Research output: Contribution to journalArticle

Autoimmune Experimental Encephalomyelitis
Phagocytes
Axons
Encephalomyelitis
Brain

Ekbom's syndrome: Lipomas, ataxia, and neuropathy with MERRF

Calabresi, P., Silvestri, G., DiMauro, S. & Griggs, R. C., 1994, In : Muscle and Nerve. 17, 8, p. 943-945 3 p.

Research output: Contribution to journalArticle

MERRF Syndrome
Lipoma
Deafness
Ataxia
Guanine
1995

Gene-modified cells for the treatment of cancer

Whartenby, K., Abraham, G. N., Calabresi, P., Abboud, C. N., Calabresi, P., Marrogi, A. & Freeman, S. M., 1995, In : Pharmacology and Therapeutics. 66, 1, p. 175-190 16 p.

Research output: Contribution to journalArticle

Genetic Therapy
Genes
Neoplasms
Insertional Mutagenesis
Therapeutics
1996

Cytokine phenotype of human autoreactive T cell clones specific for the immunodominant myelin basic protein peptide (83-99)

Hemmer, B., Vergelli, M., Calabresi, P., Huang, T., McFarland, H. F. & Martin, R., Sep 15 1996, In : Journal of Neuroscience Research. 45, 6, p. 852-862 11 p.

Research output: Contribution to journalArticle

Clone Cells
Cytokines
T-Lymphocytes
Phenotype
Multiple Sclerosis

MRI studies of multiple sclerosis: implications for the natural history of the disease and for monitoring effectiveness of experimental therapies.

McFarland, H. F., Stone, L. A., Calabresi, P., Maloni, H., Bash, C. N. & Frank, J. A., Nov 1996, In : Multiple Sclerosis. 2, 4, p. 198-205 8 p.

Research output: Contribution to journalArticle

Investigational Therapies
Multiple Sclerosis
Magnetic Resonance Imaging
Gadolinium DTPA
Relapsing-Remitting Multiple Sclerosis
1997

A sensitive ELISPOT assay to detect low-frequency human T lymphocytes

McCutcheon, M., Wehner, N., Wensky, A., Kushner, M., Doan, S., Hsiao, L., Calabresi, P., Ha, T., Tran, T. V., Tate, K. M., Winkelhake, J. & Spack, E. G., Dec 29 1997, In : Journal of Immunological Methods. 210, 2, p. 149-166 18 p.

Research output: Contribution to journalArticle

Enzyme-Linked Immunospot Assay
Blood Cells
T-Lymphocytes
Antigens
Cytokines

Association of human herpes virus 6 (HHV-6) with multiple sclerosis: Increased IgM response to HHV-6 early antigen and detection of serum HHV-6 DNA

Soldan, S. S., Berti, R., Salem, N., Secchiero, P., Flamand, L., Calabresi, P., Brennan, M. B., Maloni, H. W., Mcfarland, H. F., Lin, H. C., Patnaik, M. & Jacobson, S., Dec 1997, In : Nature Medicine. 3, 12, p. 1394-1397 4 p.

Research output: Contribution to journalArticle

DNA Viruses
Viruses
Multiple Sclerosis
Immunoglobulin M
Antigens

Astrocyte-specific expression of human T-cell lymphotropic virus type 1 (HTLV-1) Tax: Induction of tumor necrosis factor alpha and susceptibility to lysis by CD8+ HTLV-1-specific cytotoxic T cells

Méndez, E., Kawanishi, T., Clemens, K., Siomi, H., Soldan, S. S., Calabresi, P., Brady, J. & Jacobson, S., Dec 1997, In : Journal of Virology. 71, 12, p. 9143-9149 7 p.

Research output: Contribution to journalArticle

Primate T-lymphotropic virus 1
Human T-lymphotropic virus 1
astrocytes
taxes
Astrocytes

Characterization of MRI response to treatment with interferon beta-1b: Contrast-enhancing MRI lesion frequency as a primary outcome measure

Stone, L. A., Frank, J. A., Albert, P. S., Bash, C. N., Calabresi, P., Maloni, H. & McFarland, H. F., Sep 1997, In : Neurology. 49, 3, p. 862-869 8 p.

Research output: Contribution to journalArticle

Outcome Assessment (Health Care)
Multiple Sclerosis
Therapeutics
Multicenter Studies
Interferon beta-1b

Increases m soluble VCAM-1 correlate with a decrease in MRI lesions in multiple sclerosis treated with interferon β-1b

Calabresi, P., Tranquill, L. R., Dambrosia, J. M., Stone, L. A., Maloni, H., Bash, C. N., Frank, J. A. & McFarland, H. F., May 1997, In : Annals of Neurology. 41, 5, p. 669-674 6 p.

Research output: Contribution to journalArticle

Vascular Cell Adhesion Molecule-1
Interferons
Multiple Sclerosis
Magnetic Resonance Spectroscopy
Therapeutics

Interferon beta results in immediate reduction of contrast-enhanced MRI lesions in multiple sclerosis patients followed by weekly MRI

Calabresi, P., Stone, L. A., Bash, C. N., Frank, J. A. & McFarland, H. F., May 1997, In : Neurology. 48, 5, p. 1446-1448 3 p.

Research output: Contribution to journalArticle

Interferon-beta
Multiple Sclerosis
Blood-Brain Barrier
Interferon-gamma
Therapeutics

VLA-4 expression on peripheral blood lymphocytes is downregulated after treatment of multiple sclerosis with interferon beta

Calabresi, P., Pelfrey, C. M., Tranquill, L. R., Maloni, H. & McFarland, H. F., Oct 1997, In : Neurology. 49, 4, p. 1111-1116 6 p.

Research output: Contribution to journalArticle

Integrin alpha4beta1
Interferon-beta
Vascular Cell Adhesion Molecule-1
Multiple Sclerosis
Down-Regulation
1998

Cytokine gene expression in cells derived from CSF of multiple sclerosis patients

Calabresi, P., Tranquill, L. R., McFarland, H. F. & Cowan, E. P., Aug 14 1998, In : Journal of Neuroimmunology. 89, 1-2, p. 198-205 8 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Cerebrospinal Fluid
Cytokines
Gene Expression
Interleukin-10

ELI-spot of TH-1 cytokine secreting PBMC's in multiple sclerosis: Correlation with MRI lesions

Calabresi, P., Fields, N. S., Farnon, E. C., Frank, J. A., Bash, C. N., Kawanashi, T., Maloni, H., Jacobson, S. & McFarland, H. F., May 15 1998, In : Journal of Neuroimmunology. 85, 2, p. 212-219 8 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Magnetic Resonance Imaging
Cytokines
Autoimmune Experimental Encephalomyelitis
Interleukin-2

Increased serum levels of soluble CD95 (APO-1/Fas) in relapsing- remitting multiple sclerosis

Zipp, F., Weller, M., Calabresi, P., Frank, J. A., Bash, C. N., Dichgans, J., McFarland, H. F. & Martin, R., Jan 1998, In : Annals of Neurology. 43, 1, p. 116-120 5 p.

Research output: Contribution to journalArticle

Relapsing-Remitting Multiple Sclerosis
Neutralizing Antibodies
Interferons
Fas Ligand Protein
Serum

Phase 1 trial of transforming growth factor beta 2 in chronic progressive MS

Calabresi, P., Fields, N. S., Maloni, H. W., Hanham, A., Carlino, J., Moore, J., Levin, M. C., Dhib-Jalbut, S., Tranquill, L. R., Austin, H., McFarland, H. F. & Racke, M. K., 1998, In : Neurology. 51, 1, p. 289-292 4 p.

Research output: Contribution to journalArticle

Chronic Progressive Multiple Sclerosis
Transforming Growth Factors
Transforming Growth Factor beta
Multiple Sclerosis
Autoimmune Experimental Encephalomyelitis
1999

Chemokines in chronic progressive neurological diseases: HTLV-1 associated myelopathy and multiple sclerosis

Calabresi, P., Martin, R. & Jacobson, S., 1999, In : Journal of NeuroVirology. 5, 1, p. 102-108 7 p.

Research output: Contribution to journalArticle

Human T-lymphotropic virus 1
Chemokine Receptors
Spinal Cord Diseases
Chemokines
Multiple Sclerosis
2000

Induction of a non-encephalitogenic type 2 T helper-cell autoimmune response in multiple sclerosis after administration of an altered peptide ligand in a placebo-controlled, randomized phase II trial

Kappos, L., Comi, G., Panitch, H., Oger, J., Antel, J., Conlon, P., Steinman, L., Comi, G., Kappos, L., Oger, J., Panitch, H., Rae-Grant, A., Castaldo, J., Calabresi, P., Guarnaccia, J. B., Mills, P., Johnson, G., Calabresi, P. A., Pozzilli, C., Bastianello, S. & 31 others, Giugni, E., Witjas, T., Cozzone, P., Pelletier, J., Pöhlau, D., Przuntek, H., Hoffmann, V., Bever, C., Katz, E., Clanet, M., Berry, I., Brassat, D., Brunet, I., Edan, G., Duquette, P., Radue, E. W., Schött, D., Lienert, C., Taksaoui, A., Rodegher, M., Filippi, M., Evans, A., Bourgouin, P., Zijdenbos, A., Salem, S., Ling, N., Alleva, D., Johnson, E., Gaur, A., Crowe, P. & Liu, X. J., 2000, In : Nature Medicine. 6, 10, p. 1176-1182 7 p.

Research output: Contribution to journalArticle

Th2 Cells
Autoimmunity
Multiple Sclerosis
Placebos
Ligands
2001

T lymphocytes conditioned with Interferon β induce membrane and soluble VCAM on human brain endothelial cells

Calabresi, P., Prat, A., Biernacki, K., Rollins, J. & Antel, J. P., Apr 2 2001, In : Journal of Neuroimmunology. 115, 1-2, p. 161-167 7 p.

Research output: Contribution to journalArticle

Vascular Cell Adhesion Molecule-1
Interferons
Endothelial Cells
T-Lymphocytes
Membranes
2002

An open-label trial of combination therapy with interferon β-1a and oral methotrexate in MS

Calabresi, P., Wilterdink, J. L., Rogg, J. M., Mills, P., Webb, A. & Whartenby, K., Jan 22 2002, In : Neurology. 58, 2, p. 314-317 4 p.

Research output: Contribution to journalArticle

Methotrexate
Interferons
Gadolinium
Nausea
Therapeutics

Chemokine receptor expression on MBP-reactive T cells: CXCR6 is a marker of IFNγ-producing effector cells

Calabresi, P., Yun, S. H., Allie, R. & Whartenby, K., 2002, In : Journal of Neuroimmunology. 127, 1-2, p. 96-105 10 p.

Research output: Contribution to journalArticle

Myelin Basic Protein
Chemokine Receptors
T-Lymphocytes
Cell Line
Tetanus Toxoid

Comparative study of the presence of Chlamydia pneumoniae in cerebrospinal fluid of patients with clinically definite and monosymptomatic multiple sclerosis

Sriram, S., Yao, S. Y., Stratton, C., Calabresi, P., Mitchell, W., Ikejima, H. & Yamamoto, Y., Nov 2002, In : Clinical and Diagnostic Laboratory Immunology. 9, 6, p. 1332-1337 6 p.

Research output: Contribution to journalArticle

Disease control
Cerebrospinal fluid
Chlamydophila pneumoniae
Multiple Sclerosis
Cerebrospinal Fluid

Considerations in the treatment of relapsing-remitting multiple sclerosis

Calabresi, P., Apr 23 2002, In : Neurology. 58, 8 SUPPL. 5

Research output: Contribution to journalArticle

Relapsing-Remitting Multiple Sclerosis
Interferons
Therapeutics
Pharmaceutical Preparations
Recurrence

Impaired renal function in progressive multiple sclerosis

Calabresi, P., Austin, H., Racke, M. K., Goodman, A., Choyke, P., Maloni, H. & McFarland, H. F., Dec 10 2002, In : Neurology. 59, 11, p. 1799-1801 3 p.

Research output: Contribution to journalArticle

Glomerular Filtration Rate
Multiple Sclerosis
Kidney
2003

Erratum: The voltage-gated Kv1.3 K+ channel in effector memory T cells as new target for MS (Journal of Clinical Investigation (2003) 111 (1703-1713))

Wulff, H., Calabresi, P., Allie, R., Yun, S., Pennington, M., Beeton, C. & Chandy, K. G., Jul 2003, In : Journal of Clinical Investigation. 112, 2, p. 298 1 p.

Research output: Contribution to journalArticle

Voltage-Gated Potassium Channels
T-Lymphocytes

Kinetics of CCR7 expression differ between primary activation and effector memory states of TH1 and TH2 cells

Calabresi, P., Allie, R., Mullen, K. M., Yun, S. H., Georgantas, R. W. & Whartenby, K., Jun 2003, In : Journal of Neuroimmunology. 139, 1-2, p. 58-65 8 p.

Research output: Contribution to journalArticle

Cell Line
T-Lymphocytes
T-Cell Antigen Receptor
Autoimmune Diseases
Lymph Nodes

The utility of MRI in suspected MS: Report of the therapeutics and technology assessment subcommittee of the American Academy of Neurology

Frohman, E. M., Goodin, D. S., Calabresi, P., Corboy, J. R., Coyle, P. K., Filippi, M., Frank, J. A., Galetta, S. L., Grossman, R. I., Hawker, K., Kachuck, N. J., Levin, M. C., Phillips, J. T., Racke, M. K., Rivera, V. M. & Stuart, W. H., Sep 9 2003, In : Neurology. 61, 5, p. 602-611 10 p.

Research output: Contribution to journalArticle

Biomedical Technology Assessment
Gadolinium
Therapeutics
Magnetic Resonance Imaging
Prospective Studies

The voltage-gated Kv1.3 K+ channel in effector memory T cells as new target for MS

Wulff, H., Calabresi, P., Allie, R., Yun, S., Pennington, M., Beeton, C. & Chandy, K. G., Jun 2003, In : Journal of Clinical Investigation. 111, 11, p. 1703-1713 11 p.

Research output: Contribution to journalArticle

Voltage-Gated Potassium Channels
T-Lymphocytes
Myelin Sheath
Phenotype
Sea Anemones
2004

Cytokines and other inflammatory mediators of axonal injury

Calabresi, P., Apr 2004, In : Advanced Studies in Medicine. 4, 4 B

Research output: Contribution to journalArticle

Cytokines
Multiple Sclerosis
T-Lymphocytes
Wounds and Injuries
Central Nervous System

Diagnosis and management of multiple sclerosis

Calabresi, P., Nov 15 2004, In : American Family Physician. 70, 10, p. 1935-1944 10 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Fatigue
Spinal Cord
Urinary Bladder
Vitamin B 12 Deficiency

Interferon-β-1b slows progression of atrophy in RRMS: Three-year follow-up in NAb- and NAb+ patients

Frank, J. A., Richert, N., Bash, C., Stone, L., Calabresi, P., Lewis, B., Stone, R., Howard, T. & McFarland, H. F., Mar 9 2004, In : Neurology. 62, 5, p. 719-725 7 p.

Research output: Contribution to journalArticle

Relapsing-Remitting Multiple Sclerosis
Neutralizing Antibodies
Interferons
Atrophy
Brain

Kv1.3-blocking 5-phenylalkoxypsoralens: A new class of immunomodulators

Vennekamp, J., Wulff, H., Beeton, C., Calabresi, P., Grissmer, S., Hänsel, W. & Chandy, K. G., Jun 2004, In : Molecular Pharmacology. 65, 6, p. 1364-1374 11 p.

Research output: Contribution to journalArticle

Immunologic Factors
T-Lymphocytes
Kv1.3 Potassium Channel
Kv1.2 Potassium Channel
Calcium-Activated Potassium Channels

Neurodegeneration and neuroprotection in multiple sclerosis

Greenstein, J. I. & Calabresi, P., Apr 2004, In : Advanced Studies in Medicine. 4, 4 B

Research output: Contribution to journalArticle

Multiple Sclerosis
Neuroprotection
2005
Autoimmune Diseases of the Nervous System
Neural Pathways
Baltimore
Cell Movement
B-Lymphocytes

Anti-α4 integrin therapy for multiple sclerosis: Mechanisms and rationale

Rice, G. P. A., Hartung, H. P. & Calabresi, P., Apr 26 2005, In : Neurology. 64, 8, p. 1336-1342 7 p.

Research output: Contribution to journalArticle

Integrins
Multiple Sclerosis
Integrin alpha4beta1
Cell Movement
Therapeutics

Bystander modulation of chemokine receptor expression on peripheral blood T lymphocytes mediated by glatiramer therapy

Allie, R., Hu, L., Mullen, K. M., Dhib-Jalbut, S. & Calabresi, P., Jun 2005, In : Archives of Neurology. 62, 6, p. 889-894 6 p.

Research output: Contribution to journalArticle

Chemokine Receptors
T-Lymphocytes
Multiple Sclerosis
Therapeutics
Cytokines

IL-6 induces regionally selective spinal cord injury in patients with the neuroinflammatory disorder transverse myelitis

Kaplin, A. I., Deshpande, D. M., Scott, E., Krishnan, C., Carmen, J. S., Shats, I., Martinez, T., Drummond, J., Dike, S., Pletnikov, M., Keswani, S. C., Moran, T. H., Pardo-Villamizar, C. A., Calabresi, P. & Kerr, D. A., Oct 2005, In : Journal of Clinical Investigation. 115, 10, p. 2731-2741 11 p.

Research output: Contribution to journalArticle

Transverse Myelitis
Spinal Cord Injuries
Interleukin-6
Poly(ADP-ribose) Polymerases
Demyelinating Diseases

Inhibition of FLT3 signaling targets DCs to ameliorate autoimmune disease

Whartenby, K., Calabresi, P., McCadden, E., Nguyen, B., Kardian, D., Wang, T., Mosse, C., Pardoll, A. M. & Small, D., Nov 15 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 46, p. 16741-16746 6 p.

Research output: Contribution to journalArticle

Dendritic Cells
Autoimmune Diseases
T-Lymphocytes
Antigen-Presenting Cells
Autoimmune Experimental Encephalomyelitis

Interferon-β-1a induces increases in vascular cell adhesion molecule: Implications for its mode of action in multiple sclerosis

Graber, J., Zhan, M., Ford, D., Kursch, F., Francis, G., Bever, C., Panitch, H., Calabresi, P. & Dhib-Jalbut, S., Apr 2005, In : Journal of Neuroimmunology. 161, 1-2, p. 169-176 8 p.

Research output: Contribution to journalArticle

Vascular Cell Adhesion Molecule-1
Interferons
Multiple Sclerosis
Therapeutics

Multiple sclerosis: Approaches to early diagnosis and new treatment options

Calabresi, P., Jul 2005, In : Advanced Studies in Medicine. 5, 7, p. 368-375 8 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Early Diagnosis
Signs and Symptoms
Therapeutics
Expert Testimony

Neurodegeneration and neuroprotection in multiple sclerosis

Calabresi, P. & Greenstein, J. I., Apr 2005, In : Advanced Studies in Medicine. 5, 4 D

Research output: Contribution to journalArticle

Multiple Sclerosis
Neuroprotection

Optimization of the safety and efficacy of interferon beta 1b and azathioprine combination therapy in multiple sclerosis

Pulicken, M., Bash, C. N., Costello, K., Said, A., Cuffari, C., Wilterdink, J. L., Rogg, J. M., Mills, P. & Calabresi, P., Apr 2005, In : Multiple Sclerosis. 11, 2, p. 169-174 6 p.

Research output: Contribution to journalArticle

Azathioprine
Multiple Sclerosis
Magnetic Resonance Imaging
Safety
Leukopenia

Targeting effector memory T cells with a selective peptide inhibitor of Kv1.3 channels for therapy of autoimmune diseases

Beeton, C., Pennington, M. W., Wulff, H., Singh, S., Nugent, D., Crossley, G., Khaytin, I., Calabresi, P., Chen, C. Y., Gutman, G. A. & Chandy, K. G., Apr 2005, In : Molecular Pharmacology. 67, 4, p. 1369-1381 13 p.

Research output: Contribution to journalArticle

Autoimmune Diseases
T-Lymphocytes
Peptides
Sea Anemones
Voltage-Gated Potassium Channels

The voltage-gated potassium channel Kv1.3 is highly expressed on inflammatory infiltrates in multiple sclerosis brain

Rus, H., Pardo-Villamizar, C. A., Hu, L., Darrah, E., Cudrici, C., Niculescu, T., Niculescu, F., Mullen, K. M., Allie, R., Guo, L., Wulff, H., Beeton, C., Judge, S. I. V., Kerr, D. A., Knaus, H. G., Chandy, K. G. & Calabresi, P., Aug 2 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 31, p. 11094-11099 6 p.

Research output: Contribution to journalArticle

Voltage-Gated Potassium Channels
Multiple Sclerosis
Brain
T-Lymphocytes
Cerebrospinal Fluid
2006

Cleavage of cystatin C in the cerebrospinal fluid of patients with multiple sclerosis

Irani, D. N., Anderson, C., Gundry, R., Cotter, R. J., Moore, S., Kerr, D. A., McArthur, J. C., Sacktor, N., Pardo-Villamizar, C. A., Jones, M., Calabresi, P. & Nath, A., Feb 2006, In : Annals of Neurology. 59, 2, p. 237-247 11 p.

Research output: Contribution to journalArticle

Cystatin C
Multiple Sclerosis
Cerebrospinal Fluid
Transverse Myelitis
Virus Diseases

Granzyme B mediates neurotoxicity through a G-protein-coupled receptor

Wang, T., Allie, R., Conant, K., Haughey, N., Turchan-Chelowo, J., Hahn, K., Rosen, A., Steiner, J., Keswani, S., Jones, M., Calabresi, P. & Nath, A., Jun 2006, In : FASEB Journal. 20, 8

Research output: Contribution to journalArticle

Granzymes
neurotoxicity
G-Protein-Coupled Receptors
T-cells
T-lymphocytes

Immune reconstitution inflammatory syndrome in the CNS of HIV-infected patients

Venkataramana, A., Pardo-Villamizar, C. A., McArthur, J. C., Kerr, D. A., Irani, D. N., Griffin, J. W., Burger, P., Reich, D. S., Calabresi, P. & Nath, A., Aug 2006, In : Neurology. 67, 3, p. 383-388 6 p.

Research output: Contribution to journalArticle

Immune Reconstitution Inflammatory Syndrome
HIV
Adrenal Cortex Hormones
Neurologic Manifestations
Cryptococcal Meningitis

Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases

Beeton, C., Wulff, H., Standifer, N. E., Azam, P., Mullen, K. M., Pennington, M. W., Kolski-Andreaco, A., Wei, E., Grino, A., Counts, D. R., Wang, P. H., LeeHealey, C. J., Andrews, B. S., Sankaranarayanan, A., Homerick, D., Roeck, W. W., Tehranzadeh, J., Stanhope, K. L., Zimin, P., Havel, P. J. & 6 others, Griffey, S., Knaus, H. G., Nepom, G. T., Gutman, G. A., Calabresi, P. & Chandy, K. G., Nov 14 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 46, p. 17414-17419 6 p.

Research output: Contribution to journalArticle

Autoimmune Diseases
T-Lymphocytes
Immunological Synapses
Type 1 Diabetes Mellitus
Kv1.3 Potassium Channel