Research Output 1989 2018

2018

Advances in multiple sclerosis: from reduced relapses to remedies

Calabresi, P. A. Jan 1 2018 In : The Lancet Neurology. 17, 1, p. 10-12 3 p.

Research output: Contribution to journalComment/debate

Multiple Sclerosis
Recurrence

Dice overlap measures for objects of unknown number: Application to lesion segmentation

Oguz, I., Carass, A., Pham, D. L., Roy, S., Subbana, N., Calabresi, P. A., Yushkevich, P. A., Shinohara, R. T. & Prince, J. L. Jan 1 2018 Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries - 3rd International Workshop, BrainLes 2017, Held in Conjunction with MICCAI 2017, Revised Selected Papers. Springer Verlag, p. 3-14 12 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 10670 LNCS)

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Dice
Overlap
Segmentation
Unknown
Image segmentation

Dimethyl fumarate treatment alters NK cell function in multiple sclerosis

Smith, M. D., Calabresi, P. A. & Bhargava, P. Feb 1 2018 In : European Journal of Immunology. 48, 2, p. 380-383 4 p.

Research output: Contribution to journalLetter

Natural Killer Cells
Multiple Sclerosis
Dimethyl Fumarate

Distinguishing among multiple sclerosis fallers, near-fallers and non-fallers

Fritz, N. E., Eloyan, A., Baynes, M., Newsome, S. D., Calabresi, P. A. & Zackowski, K. M. Jan 1 2018 In : Multiple Sclerosis and Related Disorders. 19, p. 99-104 6 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Walking
Logistic Models
Rehabilitation

Intensity inhomogeneity correction of SD-OCT data using macular flatspace

Lang, A., Carass, A., Jedynak, B. M., Solomon, S. D., Calabresi, P. A. & Prince, J. L. Jan 1 2018 In : Medical Image Analysis. 43, p. 85-97 13 p.

Research output: Contribution to journalArticle

Optical tomography
Optical Coherence Tomography
Retina

Joint intensity fusion image synthesis applied to multiple sclerosis lesion segmentation

Fleishman, G. M., Valcarcel, A., Pham, D. L., Roy, S., Calabresi, P. A., Yushkevich, P., Shinohara, R. T. & Oguz, I. Jan 1 2018 Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries - 3rd International Workshop, BrainLes 2017, Held in Conjunction with MICCAI 2017, Revised Selected Papers. Springer Verlag, p. 43-54 12 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 10670 LNCS)

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Multiple Sclerosis
Image fusion
Image Fusion
Labels
Segmentation

MIMoSA: An Automated Method for Intermodal Segmentation Analysis of Multiple Sclerosis Brain Lesions

Valcarcel, A. M., Linn, K. A., Vandekar, S. N., Satterthwaite, T. D., Muschelli, J., Calabresi, P. A., Pham, D. L., Martin, M. L. & Shinohara, R. T. Jan 1 2018 (Accepted/In press) In : Journal of Neuroimaging.

Research output: Contribution to journalArticle

Multiple Sclerosis
Logistic Models
Brain
Magnetic Resonance Imaging
Benchmarking
2017

Analysis of Agreement of Retinal-Layer Thickness Measures Derived from the Segmentation of Horizontal and Vertical Spectralis OCT Macular Scans

Gonzalez Caldito, N., Antony, B., He, Y., Lang, A., Nguyen, J., Rothman, A., Ogbuokiri, E., Avornu, A., Balcer, L., Frohman, E., Frohman, T. C., Bhargava, P., Prince, J., Calabresi, P. A. & Saidha, S. Dec 15 2017 (Accepted/In press) In : Current Eye Research. p. 1-9 9 p.

Research output: Contribution to journalArticle

Retinaldehyde
Optical Coherence Tomography
Multiple Sclerosis
Nerve Fibers
Ganglia

B-cell depletion - A frontier in monoclonal antibodies for multiple sclerosis

Calabresi, P. A. Jan 19 2017 In : New England Journal of Medicine. 376, 3, p. 280-282 3 p.

Research output: Contribution to journalEditorial

Murine-Derived Monoclonal Antibodies
CD20 Antigens
Antibodies, Monoclonal, Humanized
Multiple Sclerosis
B-Lymphocytes

Characteristics of morphologic macular abnormalities in neuroimmunology practice

Al-Louzi, O., Sotirchos, E. S., Vidal-Jordana, A., Beh, S. C., Button, J., Ying, H. S., Balcer, L. J., Frohman, E. M., Saidha, S., Calabresi, P. A. & Newsome, S. D. Nov 1 2017 (Accepted/In press) In : Multiple Sclerosis Journal.

Research output: Contribution to journalArticle

Neuromyelitis Optica
Epiretinal Membrane
Optical Coherence Tomography
Multiple Sclerosis
Odds Ratio

CNS-targeted autoimmunity leads to increased influenza mortality in mice

Glenn, J. D., Smith, M. D., Xue, P., Chan-Li, Y., Collins, S., Calabresi, P. A., Horton, M. R. & Whartenby, K. A. 2017 In : Journal of Experimental Medicine. 214, 2, p. 297-307 11 p.

Research output: Contribution to journalArticle

Autoimmune Experimental Encephalomyelitis
Autoimmunity
Human Influenza
Central Nervous System
Lung

Disease-modifying therapies modulate retinal atrophy in multiple sclerosis: A retrospective study

Button, J., Al-Louzi, O., Lang, A., Bhargava, P., Newsome, S. D., Frohman, T., Balcer, L. J., Frohman, E. M., Prince, J., Calabresi, P. A. & Saidha, S. Feb 7 2017 In : Neurology. 88, 6, p. 525-532 8 p.

Research output: Contribution to journalArticle

Optical Coherence Tomography
Multiple Sclerosis
Atrophy
Relapsing-Remitting Multiple Sclerosis
Retrospective Studies

From neurofilament research to multiple sclerosis clinical practice: Where do we stand?

Bodini, B. & Calabresi, P. A. Feb 28 2017 In : Neurology. 88, 9, p. 816-817 2 p.

Research output: Contribution to journalEditorial

Intermediate Filaments
Multiple Sclerosis
Research

Gradient nonlinearity effects on upper cervical spinal cord area measurement from 3D T1-weighted brain MRI acquisitions

Papinutto, N. , Bakshi, R. , Bischof, A. , Calabresi, P. A. , Caverzasi, E. , Constable, R. T. , Datta, E. , Kirkish, G. , Nair, G. , Oh, J. , Pelletier, D. , Pham, D. L. , Reich, D. S. , Rooney, W. , Roy, S. , Schwartz, D. , Shinohara, R. T. , Sicotte, N. L. , Stern, W. A. , Tagge, I. & 3 others Tauhid, S., Tummala, S. & Henry, R. G. 2017 (Accepted/In press) In : Magnetic Resonance in Medicine.

Research output: Contribution to journalArticle

Brain
Multiple Sclerosis
Healthy Volunteers
Cervical Cord

Lineage tracing reveals dynamic changes in oligodendrocyte precursor cells following cuprizone-induced demyelination

Baxi, E. G., Debruin, J., Jin, J., Strasburger, H. J., Smith, M. D., Orthmann-Murphy, J. L., Schott, J. T., Fairchild, A. N., Bergles, D. E. & Calabresi, P. A. 2017 (Accepted/In press) In : GLIA.

Research output: Contribution to journalArticle

Cuprizone
Oligodendroglia
Demyelinating Diseases
Stem Cells
Corpus Callosum

Longitudinal multiple sclerosis lesion segmentation: Resource and challenge

Carass, A. , Roy, S. , Jog, A. , Cuzzocreo, J. L. , Magrath, E. , Gherman, A. , Button, J. , Nguyen, J. , Prados, F. , Sudre, C. H. , Jorge Cardoso, M. , Cawley, N. , Ciccarelli, O. , Wheeler-Kingshott, C. A. M. , Ourselin, S. , Catanese, L. , Deshpande, H. , Maurel, P. , Commowick, O. , Barillot, C. & 26 others Tomas-Fernandez, X., Warfield, S. K., Vaidya, S., Chunduru, A., Muthuganapathy, R., Krishnamurthi, G., Jesson, A., Arbel, T., Maier, O., Handels, H., Iheme, L. O., Unay, D., Jain, S., Sima, D. M., Smeets, D., Ghafoorian, M., Platel, B., Birenbaum, A., Greenspan, H., Bazin, P. L., Calabresi, P. A., Crainiceanu, C. M., Ellingsen, L. M., Reich, D. S., Prince, J. L. & Pham, D. L. Mar 1 2017 In : NeuroImage. 148, p. 77-102 26 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Research Personnel
Research
Datasets

Longitudinal multiple sclerosis lesion segmentation data resource

Carass, A., Roy, S., Jog, A., Cuzzocreo, J. L., Magrath, E., Gherman, A., Button, J., Nguyen, J., Bazin, P. L., Calabresi, P. A., Crainiceanu, C. M., Ellingsen, L. M., Reich, D. S., Prince, J. L. & Pham, D. L. Jun 1 2017 In : Data in Brief. 12, p. 346-350 5 p.

Research output: Contribution to journalArticle

multiple sclerosis
resources
segmentation
website
expert

Multiple Sclerosis Lesion Segmentation Using Joint Label Fusion

Dong, M., Oguz, I., Subbana, N., Calabresi, P., Shinohara, R. T. & Yushkevich, P. 2017 Patch-Based Techniques in Medical Imaging - 3rd International Workshop, Patch-MI 2017 Held in Conjunction with MICCAI 2017, Proceedings. Springer Verlag, Vol. 10530 LNCS, p. 138-145 8 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 10530 LNCS)

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Multiple Sclerosis
Atlas
Labels
Fusion
Fusion reactions

Neuropsychiatric syndromes of multiple sclerosis

Murphy, R., O'Donoghue, S., Counihan, T., McDonald, C., Calabresi, P. A., Ahmed, M. A. S., Kaplin, A. & Hallahan, B. Aug 1 2017 In : Journal of Neurology, Neurosurgery and Psychiatry. 88, 8, p. 697-708 12 p.

Research output: Contribution to journalReview article

Multiple Sclerosis
Neuroimaging
Signs and Symptoms
Disease Progression
Mental Health
Optical Coherence Tomography
Multiple Sclerosis
Neurodegenerative Diseases
Biomarkers
Technology
Relapsing-Remitting Multiple Sclerosis
Randomized Controlled Trials
Magnetic Resonance Imaging
Odds Ratio
Brain

Quantitative measures of walking and strength provide insight into brain corticospinal tract pathology in multiple sclerosis

Fritz, N. E., Keller, J., Calabresi, P. A. & Zackowski, K. M. 2017 In : NeuroImage: Clinical. 14, p. 490-498 9 p.

Research output: Contribution to journalArticle

Pyramidal Tracts
Multiple Sclerosis
Walking
Pathology
Brain

Retinal architecture and melanopsin-mediated pupillary response characteristics: A putative pathophysiologic signature for the retino-hypothalamic tract in multiple sclerosis

Meltzer, E., Sguigna, P. V., Subei, A., Beh, S., Kildebeck, E., Conger, D., Conger, A., Lucero, M., Frohman, B. S., Frohman, A. N., Saidha, S., Galetta, S., Calabresi, P. A., Rennaker, R., Frohman, T. C., Kardon, R. H., Balcer, L. J. & Frohman, E. M. May 1 2017 In : JAMA Neurology. 74, 5, p. 574-582 9 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Constriction
Optical Coherence Tomography
Light
Retina

Retinal degeneration in primary-progressive multiple sclerosis: A role for cortical lesions?

Petracca, M., Cordano, C., Cellerino, M., Button, J., Krieger, S., Vancea, R., Ghassemi, R., Farrell, C., Miller, A., Calabresi, P. A., Lublin, F. & Inglese, M. 2017 In : Multiple Sclerosis. 23, 1, p. 43-50 8 p.

Research output: Contribution to journalArticle

Chronic Progressive Multiple Sclerosis
Retinal Degeneration
Ganglia
Nerve Fibers
Visual Pathways

Retrograde trans-synaptic visual pathway degeneration in multiple sclerosis: A case series

Al-Louzi, O., Button, J., Newsome, S. D., Calabresi, P. A. & Saidha, S. Jun 1 2017 In : Multiple Sclerosis. 23, 7, p. 1035-1039 5 p.

Research output: Contribution to journalArticle

Retrograde Degeneration
Visual Pathways
Ganglia
Multiple Sclerosis
Nervous System

Thalamus segmentation using multi-modal feature classification: Validation and pilot study of an age-matched cohort

Glaister, J., Carass, A., NessAiver, T., Stough, J. V., Saidha, S., Calabresi, P. A. & Prince, J. L. Sep 1 2017 In : NeuroImage. 158, p. 430-440 11 p.

Research output: Contribution to journalArticle

Validation Studies
Thalamus
Diffusion Tensor Imaging
Atlases
Multiple Sclerosis

The NAIMS cooperative pilot project: Design, implementation and future directions

on behalf of the NAIMS Cooperative Steering Committee Oct 1 2017 (Accepted/In press) In : Multiple Sclerosis Journal.

Research output: Contribution to journalArticle

North America
Multiple Sclerosis
Magnetic Resonance Imaging
Multicenter Studies
Direction compound

Therapeutic Application of Monoclonal Antibodies in Multiple Sclerosis

Orthmann-Murphy, J. L. & Calabresi, P. A. Jan 1 2017 In : Clinical Pharmacology and Therapeutics. 101, 1, p. 52-64 13 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Monoclonal Antibodies
Therapeutics
Central Nervous System
Immunomodulation

Towards topological correct segmentation of macular OCT from cascaded FCNs

He, Y., Carass, A., Yun, Y., Zhao, C., Jedynak, B. M., Solomon, S. D., Saidha, S., Calabresi, P. A. & Prince, J. L. 2017 Fetal, Infant and Ophthalmic Medical Image Analysis - International Workshop, FIFI 2017 and 4th International Workshop, OMIA 2017 Held in Conjunction with MICCAI 2017, Proceedings. Springer Verlag, Vol. 10554 LNCS, p. 202-209 8 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 10554 LNCS)

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Optical Coherence Tomography
Optical tomography
Retina
Segmentation
Topology
2016

20/40 or better visual acuity after optic neuritis: Not as good as we once thought?

Sabadia, S. B., Nolan, R. C., Galetta, K. M., Narayana, K. M., Wilson, J. A., Calabresi, P. A., Frohman, E. M., Galetta, S. L. & Balcer, L. J. 2016 In : Journal of Neuro-Ophthalmology. 36, 4, p. 369-376 8 p.

Research output: Contribution to journalArticle

Optic Neuritis
Visual Acuity
Nerve Fibers
Ganglia
Quality of Life

Adapted resistance training improves strength in eight weeks in individuals with multiple sclerosis

Keller, J. L., Fritz, N., Chiang, C. C., Jiang, A., Thompson, T., Cornet, N., Newsome, S. D., Calabresi, P. A. & Zackowski, K. Jan 29 2016 In : Journal of Visualized Experiments. 2016, 107, e53449

Research output: Contribution to journalArticle

Resistance Training
Multiple Sclerosis
Education
Hip
Direction compound

Author Response

Sotirchos, E. S. & Calabresi, P. A. Sep 27 2016 In : Neurology. 87, 13, p. 1424 1 p.

Research output: Contribution to journalLetter

Combined registration and motion correction of longitudinal retinal OCT data

Lang, A., Carass, A., Al-Louzi, O., Bhargava, P., Solomon, S. D., Calabresi, P. A. & Prince, J. L. 2016 Medical Imaging 2016: Image Processing. SPIE, Vol. 9784, 97840X

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Optical tomography
Optical Coherence Tomography
tomography
Thickness measurement
Eye movements

Differentiating neuromyelitis optica from other causes of longitudinally extensive transverse myelitis on spinal magnetic resonance imaging

Pekcevik, Y., Mitchell, C. H., Mealy, M. A., Orman, G., Lee, I. H., Newsome, S. D., Thompson, C. B., Pardo, C. A., Calabresi, P. A., Levy, M. & Izbudak, I. 2016 In : Multiple Sclerosis. 22, 3, p. 302-311 10 p.

Research output: Contribution to journalArticle

Transverse Myelitis
Neuromyelitis Optica
Magnetic Resonance Imaging
Spinal Cord
Brain

How global MS prevalence is changing: A retrospective chart review in the United Arab Emirates

Schiess, N., Huether, K., Fatafta, T., Fitzgerald, K. C., Calabresi, P. A., Blair, I., Alsaadi, T. & Szolics, M. Sep 1 2016 In : Multiple Sclerosis and Related Disorders. 9, p. 73-79 7 p.

Research output: Contribution to journalArticle

United Arab Emirates
Multiple Sclerosis
Middle East
Incidence
Age of Onset

Increased TNFR1 expression and signaling in injured peripheral nerves of mice with reduced BACE1 activity

Liu, L., Fissel, J. A., Tasnim, A., Borzan, J., Gocke, A., Calabresi, P. A. & Farah, M. H. Sep 1 2016 In : Neurobiology of Disease. 93, p. 21-27 7 p.

Research output: Contribution to journalArticle

Tumor Necrosis Factor Receptors
Peripheral Nerves
Enzymes
Macrophages
Knockout Mice

Intensity inhomogeneity correction of macular OCT using N3 and retinal flatspace

Lang, A., Carass, A., Jedynak, B. M., Solomon, S. D., Calabresi, P. A. & Prince, J. L. Jun 15 2016 2016 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2016 - Proceedings. IEEE Computer Society, Vol. 2016-June, p. 197-200 4 p. 7493243

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Optical tomography
Optical Coherence Tomography
Magnetic resonance imaging
Retina
Imaging techniques

Is my MS patient failing treatment?

Butzkueven, H. & Calabresi, P. A. Jul 12 2016 In : Neurology. 87, 2, p. 124-125 2 p.

Research output: Contribution to journalEditorial

Therapeutics

Lesion heterogeneity on high-field susceptibility MRI Is associated with multiple sclerosis severity

Harrison, D. M., Li, X., Liu, H., Jones, C. K., Caffo, B., Calabresi, P. A. & Van Zijl, P. Aug 1 2016 In : American Journal of Neuroradiology. 37, 8, p. 1447-1453 7 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Fatigue
Oligodendroglia
Iron
Inflammation

Magnetic susceptibility contrast variations in multiple sclerosis lesions

Li, X., Harrison, D. M., Liu, H., Jones, C. K., Oh, J., Calabresi, P. A. & Van Zijl, P. C. M. Feb 1 2016 In : Journal of Magnetic Resonance Imaging. 43, 2, p. 463-473 11 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Magnetic Resonance Imaging
Masks
Myelin Sheath
Iron

Metabolomics in multiple sclerosis

Bhargava, P. & Calabresi, P. A. Apr 1 2016 In : Multiple Sclerosis. 22, 4, p. 451-460 10 p.

Research output: Contribution to journalArticle

Metabolomics
Multiple Sclerosis
Precision Medicine
Demyelinating Diseases
Genomics

Multiple Sclerosis

Schiess, N. & Calabresi, P. A. Aug 1 2016 In : Seminars in Neurology. 36, 4, p. 350-356 7 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Immunomodulation
Neurology
Cognition
Differential Diagnosis

Outer retinal changes following acute optic neuritis

Al-Louzi, O. A., Bhargava, P., Newsome, S. D., Balcer, L. J., Frohman, E. M., Crainiceanu, C., Calabresi, P. A. & Saidha, S. 2016 In : Multiple Sclerosis. 22, 3, p. 362-372 11 p.

Research output: Contribution to journalArticle

Optic Neuritis
Ganglia
Optical Coherence Tomography
Nerve Fibers
Multiple Sclerosis

Pain, cognition and quality of life associate with structural measures of brain volume loss in multiple sclerosis

Fritz, N. E., Roy, S., Keller, J., Prince, J., Calabresi, P. A. & Zackowski, K. M. Oct 14 2016 In : NeuroRehabilitation. 39, 4, p. 535-544 10 p.

Research output: Contribution to journalArticle

Cognition
Multiple Sclerosis
Quality of Life
Pain
Brain

Phenytoin in acute optic neuritis: neuroprotective or not?

Saidha, S. & Calabresi, P. A. Mar 1 2016 In : The Lancet Neurology. 15, 3, p. 233-235 3 p.

Research output: Contribution to journalComment/debate

Voltage-Gated Sodium Channel Blockers
Optic Neuritis
Phenytoin
Neuroprotective Agents
Outcome Assessment (Health Care)
Myelin Proteins
Oligodendroglia
Neurology
Rats
Assays

Retinal thickness measured with optical coherence tomography and risk of disability worsening in multiple sclerosis: A cohort study

Martinez-Lapiscina, E. H. , Arnow, S. , Wilson, J. A. , Saidha, S. , Preiningerova, J. L. , Oberwahrenbrock, T. , Brandt, A. U. , Pablo, L. E. , Guerrieri, S. , Gonzalez, I. , Outteryck, O. , Mueller, A. K. , Albrecht, P. , Chan, W. , Lukas, S. , Balk, L. J. , Fraser, C. , Frederiksen, J. L. , Resto, J. , Frohman, T. & 23 others Cordano, C., Zubizarreta, I., Andorra, M., Sanchez-Dalmau, B., Saiz, A., Bermel, R., Klistorner, A., Petzold, A., Schippling, S., Costello, F., Aktas, O., Vermersch, P., Oreja-Guevara, C., Comi, G., Leocani, L., Garcia-Martin, E., Paul, F., Havrdova, E., Frohman, E., Balcer, L. J., Green, A. J., Calabresi, P. A. & Villoslada, P. May 1 2016 In : The Lancet Neurology. 15, 6, p. 574-584 11 p.

Research output: Contribution to journalArticle

Optical Coherence Tomography
Optic Neuritis
Multiple Sclerosis
Cohort Studies
Nerve Fibers

Safety and immunologic effects of high-vs low-dose cholecalciferol in multiple sclerosis

Sotirchos, E. S., Bhargava, P., Eckstein, C., Van Haren, K., Baynes, M., Ntranos, A., Gocke, A., Steinman, L., Mowry, E. M. & Calabresi, P. A. Jan 26 2016 In : Neurology. 86, 4, p. 382-390 9 p.

Research output: Contribution to journalArticle

Cholecalciferol
Multiple Sclerosis
T-Lymphocytes
Safety
Interleukin-17

Simultaneous segmentation of retinal surfaces and microcystic macular edema in SDOCT volumes

Antony, B. J., Lang, A., Swingle, E. K., Al-Louzi, O., Carass, A., Solomon, S., Calabresi, P. A., Saidha, S. & Prince, J. L. 2016 Medical Imaging 2016: Image Processing. SPIE, Vol. 9784, 97841C

Research output: Chapter in Book/Report/Conference proceedingConference contribution

edema
Macular Edema
Optical tomography
Optical Coherence Tomography
Imaging techniques