Research Output 1980 2017

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2017

Abnormal grey matter arteriolar cerebral blood volume in schizophrenia measured with 3D inflow-based vascular-space-occupancy MRI at 7T

Hua, J., Brandt, A. S., Lee, S. W., Blair, N. I. S., Wu, Y., Lui, S., Patel, J., Faria, A. V., Lim, I. A. L., Unschuld, P. G., Pekar, J. J., Van Zijl, P. C. M., Ross, C. A. & Margolis, R. L. 2017 In : Schizophrenia Bulletin. 43, 3, p. 620-632 13 p.

Research output: Research - peer-reviewArticle

Blood Vessels
Schizophrenia
Brain
Cerebral Blood Volume
Gray Matter
Hematocrit
Hemodynamics
Cerebrovascular Circulation
Oxygen
Magnetic Resonance Imaging
Image-Guided Biopsy
Amides
Glioma
Protons
Magnetic Resonance Spectroscopy
Cerebral Blood Volume
Photic Stimulation
Magnetic Resonance Imaging
Oxygen
Cerebrovascular Circulation

Background field removal using a region adaptive kernel for quantitative susceptibility mapping of human brain

Fang, J., Bao, L., Li, X., van Zijl, P. C. M. & Chen, Z. Aug 1 2017 In : Journal of Magnetic Resonance. 281, p. 130-140 11 p.

Research output: Research - peer-reviewArticle

brain
magnetic permeability
Brain Mapping
Brain
Tissue

Detection and Quantification of Hydrogen Peroxide in Aqueous Solutions Using Chemical Exchange Saturation Transfer

Ryoo, D., Xu, X., Li, Y., Tang, J. A., Zhang, J., Van Zijl, P. C. M. & Liu, G. Jul 18 2017 In : Analytical Chemistry. 89, 14, p. 7758-7764 7 p.

Research output: Research - peer-reviewArticle

Saturation (materials composition)
Hydrogen Peroxide
Ion exchange
Nuclear magnetic resonance
Magnetic resonance

Detection of dynamic substrate binding using MRI

Yadav, N. N., Yang, X., Li, Y., Li, W., Liu, G. & Van Zijl, P. C. M. Dec 1 2017 In : Scientific Reports. 7, 1, 10138

Research output: Research - peer-reviewArticle

Protons
Magnetic Resonance Imaging
Water
Caffeine
Radio

GlucoCEST magnetic resonance imaging in vivo may be diagnostic of acute renal allograft rejection

Kentrup, D., Bovenkamp, P., Busch, A., Schuette-Nuetgen, K., Pawelski, H., Pavenstädt, H., Schlatter, E., Herrmann, K. H., Reichenbach, J. R., Löffler, B., Heitplatz, B., Van Marck, V., Yadav, N. N., Liu, G., van Zijl, P. C. M., Reuter, S. & Hoerr, V. Sep 1 2017 In : Kidney International. 92, 3, p. 757-764 8 p.

Research output: Research - peer-reviewArticle

Allografts
Magnetic Resonance Imaging
Kidney
Glucose
T-Lymphocytes
Amides
Protons
Stroke
Proteins
Acidosis

Investigation of the contribution of total creatine to the CEST Z-spectrum of brain using a knockout mouse model

Chen, L., Zeng, H., Xu, X., Yadav, N. N., Cai, S., Puts, N. A., Barker, P. B., Li, T., Weiss, R. G., van Zijl, P. C. M. & Xu, J. Dec 1 2017 In : NMR in Biomedicine. 30, 12, e3834

Research output: Research - peer-reviewArticle

Creatine
Knockout Mice
Brain
Phosphocreatine
Guanidine

Magnetization Transfer Contrast and Chemical Exchange Saturation Transfer MRI. Features and analysis of the field-dependent saturation spectrum

van Zijl, P. C. M., Lam, W. W., Xu, J., Knutsson, L. & Stanisz, G. J. 2017 (Accepted/In press) In : NeuroImage.

Research output: Research - peer-reviewArticle

Protons
Water
Magnetic Resonance Spectroscopy
Creatine
Guanidine

Memory performance-related dynamic brain connectivity indicates pathological burden and genetic risk for Alzheimer's disease

Quevenco, F. C., Preti, M. G., Van Bergen, J. M. G., Hua, J., Wyss, M., Li, X., Schreiner, S. J., Steininger, S. C., Meyer, R., Meier, I. B., Brickman, A. M., Leh, S. E., Gietl, A. F., Buck, A., Nitsch, R. M., Pruessmann, K. P., Van Zijl, P. C. M., Hock, C., Van De Ville, D. & Unschuld, P. G. Mar 31 2017 In : Alzheimer's Research and Therapy. 9, 1, 24

Research output: Research - peer-reviewArticle

Alzheimer Disease
Iron
Brain
Apolipoproteins E
Magnetic Resonance Imaging

Predicting IDH mutation status in grade II gliomas using amide proton transfer-weighted (APTw) MRI

Jiang, S., Zou, T., Eberhart, C. G., Villalobos, M. A. V., Heo, H. Y., Zhang, Y., Wang, Y., Wang, X., Yu, H., Du, Y., van Zijl, P. C. M., Wen, Z. & Zhou, J. Sep 1 2017 In : Magnetic Resonance in Medicine. 78, 3, p. 1100-1109 10 p.

Research output: Research - peer-reviewArticle

Isocitrate Dehydrogenase
Amides
Glioma
Protons
Mutation

Subject-specific regional measures of water diffusion are associated with impairment in chronic spinal cord injury

Choe, A. S., Sadowsky, C. L., Smith, S. A., van Zijl, P. C. M., Pekar, J. J. & Belegu, V. Aug 1 2017 In : Neuroradiology. 59, 8, p. 747-758 12 p.

Research output: Research - peer-reviewArticle

Diffusion Tensor Imaging
Spinal Cord Injuries
Water
Wounds and Injuries
Biomarkers
Albumins
Hemoglobins
Erythrocytes
Water
Hemoglobin
2016

15N Heteronuclear Chemical Exchange Saturation Transfer MRI

Zeng, H., Xu, J., Yadav, N. N., McMahon, M. T., Harden, B., Frueh, D. & Van Zijl, P. C. M. Sep 7 2016 In : Journal of the American Chemical Society. 138, 35, p. 11136-11139 4 p.

Research output: Research - peer-reviewArticle

Magnetic resonance imaging
Protons
Water
Molecules
Proton transfer

Applying amide proton transfer-weighted MRI to distinguish pseudoprogression from true progression in malignant gliomas

Ma, B., Blakeley, J. O., Hong, X., Zhang, H., Jiang, S., Blair, L., Zhang, Y., Heo, H. Y., Zhang, M., van Zijl, P. C. M. & Zhou, J. Aug 1 2016 In : Journal of Magnetic Resonance Imaging. 44, 2, p. 456-462 7 p.

Research output: Research - peer-reviewArticle

Amides
Glioma
Protons
Magnetic Resonance Imaging
Research Ethics Committees
Pyramidal Tracts
Brain Stem
White Matter
Diffusion Magnetic Resonance Imaging
Anisotropy
Restless Legs Syndrome
Iron
Brain
Substantia Nigra
Sleep

CEST-MRI detects metabolite levels altered by breast cancer cell aggressiveness and chemotherapy response

Chan, K. W. Y., Jiang, L., Cheng, M., Wijnen, J. P., Liu, G., Huang, P., van Zijl, P. C. M., Mcmahon, M. T. & Glunde, K. 2016 (Accepted/In press) In : NMR in Biomedicine.

Research output: Research - peer-reviewArticle

Chemotherapy
Metabolites
Magnetic resonance imaging
Cells
Breast Neoplasms

CEST theranostics: Label-free MR imaging of anticancer drugs

Li, Y., Chen, H., Xu, J., Yadav, N. N., Chan, K. W. Y., Luo, L., McMahon, M. T., Vogelstein, B., Van Zijl, P. C. M., Zhou, S. & Liu, G. 2016 In : Oncotarget. 7, 6, p. 6369-6378 10 p.

Research output: Research - peer-reviewArticle

Pharmaceutical Preparations
Theranostic Nanomedicine
Neoplasms
gemcitabine
Folic Acid Antagonists

Colocalization of cerebral iron with Amyloid beta in Mild Cognitive Impairment

Van Bergen, J. M. G., Li, X., Hua, J., Schreiner, S. J., Steininger, S. C., Quevenco, F. C., Wyss, M., Gietl, A. F., Treyer, V., Leh, S. E., Buck, F., Nitsch, R. M., Pruessmann, K. P., Van Zijl, P. C. M., Hock, C. & Unschuld, P. G. Oct 17 2016 In : Scientific Reports. 6, 35514

Research output: Research - peer-reviewArticle

Apolipoprotein E4
Amyloid
Iron
Cognitive Dysfunction
Brain
Internal Carotid Artery
Hematocrit
Carotid Arteries
In Vitro Techniques

Label-free CEST MRI detection of citicoline-liposome drug delivery in ischemic stroke

Liu, H., Jablonska, A., Li, Y., Cao, S., Liu, D., Chen, H., Van Zijl, P. C. M., Bulte, J. W. M., Janowski, M., Walczak, P. & Liu, G. 2016 In : Theranostics. 6, 10, p. 1588-1600 13 p.

Research output: Research - peer-reviewArticle

Cytidine Diphosphate Choline
Liposomes
Stroke
Pharmaceutical Preparations
6-chloro-3,5-diaminopyrazine-3-carboxamide

Lesion heterogeneity on high-field susceptibility MRI Is associated with multiple sclerosis severity

Harrison, D. M., Li, X., Liu, H., Jones, C. K., Caffo, B., Calabresi, P. A. & Van Zijl, P. Aug 1 2016 In : American Journal of Neuroradiology. 37, 8, p. 1447-1453 7 p.

Research output: Research - peer-reviewArticle

Multiple Sclerosis
Fatigue
Oligodendroglia
Iron
Inflammation

Magnetic susceptibility contrast variations in multiple sclerosis lesions

Li, X., Harrison, D. M., Liu, H., Jones, C. K., Oh, J., Calabresi, P. A. & Van Zijl, P. C. M. Feb 1 2016 In : Journal of Magnetic Resonance Imaging. 43, 2, p. 463-473 11 p.

Research output: Research - peer-reviewArticle

Multiple Sclerosis
Magnetic Resonance Imaging
Masks
Myelin Sheath
Iron
Blood Volume
Brain Neoplasms
Contrast Media
Blood Vessels
Perfusion

On-resonance variable delay multipulse scheme for imaging of fast-exchanging protons and semisolid macromolecules

Xu, J., Chan, K. W. Y., Xu, X., Yadav, N., Liu, G. & van Zijl, P. C. M. 2016 (Accepted/In press) In : Magnetic Resonance in Medicine.

Research output: Research - peer-reviewArticle

Protons
Water
Brain
Gray Matter
Creatine

Proton chemical exchange saturation transfer (CEST) MRS and MRI

Van Zijl, P. C. M. & Sehgal, A. A. 2016 In : eMagRes. 5, 2, p. 1307-1332 26 p.

Research output: Research - peer-reviewArticle

Magnetic resonance imaging
Ion exchange
Protons
Water
Metabolites

Quantitative measurement of cerebral blood volume using velocity-selective pulse trains

Liu, D., Xu, F., Lin, D. D., van Zijl, P. C. M. & Qin, Q. 2016 (Accepted/In press) In : Magnetic Resonance in Medicine.

Research output: Research - peer-reviewArticle

Cerebral Blood Volume
Signal-To-Noise Ratio
Healthy Volunteers
Gray Matter
White Matter

Quantitative susceptibility mapping suggests altered brain iron in premanifest Huntington disease

Van Bergen, J. M. G., Hua, J., Unschuld, P. G., Lim, I. A. L., Jones, C. K., Margolis, R. L., Ross, C. A., Van Zijl, P. C. M. & Li, X. May 1 2016 In : American Journal of Neuroradiology. 37, 5, p. 789-796 8 p.

Research output: Research - peer-reviewArticle

Huntington Disease
Iron
Brain
Caudate Nucleus
Putamen

Quantitative Susceptibility Mapping Using Structural Feature Based Collaborative Reconstruction (SFCR) in the Human Brain

Bao, L., Li, X., Cai, C., Chen, Z. & Van Zijl, P. C. M. Sep 1 2016 In : IEEE Transactions on Medical Imaging. 35, 9, p. 2040-2050 11 p., 7438877

Research output: Research - peer-reviewArticle

Brain
Supine Position
Artifacts
Noise
Anatomy

Quantitative theory for the longitudinal relaxation time of blood water

Li, W., Grgac, K., Huang, A., Yadav, N., Qin, Q. & van Zijl, P. C. M. Jul 1 2016 In : Magnetic Resonance in Medicine. 76, 1, p. 270-281 12 p.

Research output: Research - peer-reviewArticle

Water
Methemoglobin
Hemoglobins
Hematocrit
Albumins

Screening CEST contrast agents using ultrafast CEST imaging

Xu, X., Yadav, N. N., Song, X., McMahon, M. T., Jerschow, A., Van Zijl, P. C. M. & Xu, J. Apr 1 2016 In : Journal of Magnetic Resonance. 265, p. 224-229 6 p.

Research output: Research - peer-reviewArticle

Contrast Media
Screening
Imaging techniques
screening
saturation

Susceptibility tensor imaging (STI) of the brain

Li, W., Liu, C., Duong, T. Q., van Zijl, P. C. M. & Li, X. 2016 (Accepted/In press) In : NMR in Biomedicine.

Research output: Research - peer-reviewArticle

Tensors
Brain
Imaging techniques
Anisotropy
Neuroimaging

Velocity-selective-inversion prepared arterial spin labeling

Qin, Q. & van Zijl, P. C. M. Oct 1 2016 In : Magnetic Resonance in Medicine. 76, 4, p. 1136-1148 13 p.

Research output: Research - peer-reviewArticle

Fourier Analysis
Cerebrovascular Circulation
Signal-To-Noise Ratio
Gray Matter
Healthy Volunteers
2015

Age-related changes in anterior cingulate cortex glutamate in schizophrenia: A 1H MRS Study at 7Tesla

Brandt, A. S., Unschuld, P. G., Pradhan, S., Lim, I. A. L., Churchill, G., Harris, A. D., Hua, J., Barker, P. B., Ross, C. A., van Zijl, P. C. M., Edden, R. A. E. & Margolis, R. L. Dec 25 2015 (Accepted/In press) In : Schizophrenia Research.

Research output: Research - peer-reviewArticle

Gyrus Cinguli
Glutamic Acid
Schizophrenia
Magnetic Resonance Spectroscopy
Glutamine
Cognition
Multiple Sclerosis
Magnetic Resonance Imaging
White Matter
Odds Ratio

Biophysical characterization of human protamine-1 as a responsive CEST MR contrast agent

Oskolkov, N., Bar-Shir, A., Chan, K. W. Y., Song, X., Van Zijl, P. C. M., Bulte, J. W. M., Gilad, A. A. & McMahon, M. T. 2015 In : ACS Macro Letters. 4, 1, p. 34-38 5 p.

Research output: Research - peer-reviewArticle

Protamines
Contrast Media
Arginine
Heparin
Phosphorylation
Blood Volume
Blood-Brain Barrier
Brain Neoplasms
Glucose
Area Under Curve

Family income, parental education and brain structure in children and adolescents

Noble, K. G. , Houston, S. M. , Brito, N. H. , Bartsch, H. , Kan, E. , Kuperman, J. M. , Akshoomoff, N. , Amaral, D. G. , Bloss, C. S. , Libiger, O. , Schork, N. J. , Murray, S. S. , Casey, B. J. , Chang, L. , Ernst, T. M. , Frazier, J. A. , Gruen, J. R. , Kennedy, D. N. , Van Zijl, P. , Mostofsky, S. & 5 others Kaufmann, W. E., Kenet, T., Dale, A. M., Jernigan, T. L. & Sowell, E. R. Apr 28 2015 In : Nature Neuroscience. 18, 5, p. 773-778 6 p.

Research output: Research - peer-reviewArticle

Education
Brain
Aptitude
Executive Function
Vulnerable Populations

Label-free in vivo molecular imaging of underglycosylated mucin-1 expression in tumour cells

Song, X., Airan, R. D., Arifin, D. R., Bar-Shir, A., Kadayakkara, D. K., Liu, G., Gilad, A. A., Van Zijl, P. C. M., McMahon, M. T. & Bulte, J. W. M. Mar 30 2015 In : Nature Communications. 6, 6719

Research output: Research - peer-reviewArticle

Molecular imaging
Mucin-1
Labels
Tumors
Cells

Large-scale genomics unveil polygenic architecture of human cortical surface area

Chen, C. H. , Peng, Q. , Schork, A. J. , Lo, M. T. , Fan, C. C. , Wang, Y. , Desikan, R. S. , Bettella, F. , Hagler, D. J. , Westlye, L. T. , Kremen, W. S. , Jernigan, T. L. , Le Hellard, S. , Steen, V. M. , Espeseth, T. , Huentelman, M. , Håberg, A. K. , Agartz, I. , Djurovic, S. , Andreassen, O. A. & 86 others Schork, N., Dale, A. M., McCabe, C., Chang, L., Akshoomoff, N., Newman, E., Ernst, T., Van Zijl, P., Kuperman, J., Murray, S., Bloss, C., Appelbaum, M., Gamst, A., Thompson, W., Bartsch, H., Weiner, M., Aisen, P., Petersen, R., Jack, C. R., Jagust, W., Trojanowki, J. Q., Toga, A. W., Beckett, L., Green, R. C., Saykin, A. J., Morris, J., Shaw, L. M., Khachaturian, Z., Sorensen, G., Carrillo, M., Kuller, L., Raichle, M., Paul, S., Davies, P., Fillit, H., Hefti, F., Holtzman, D., Mesulman, M. M., Potter, W., Snyder, P. J., Schwartz, A., Montine, T., Thomas, R. G., Donohue, M., Walter, S., Gessert, D., Sather, T., Jiminez, G., Harvey, D., Bernstein, M., Fox, N., Thompson, P., Schuff, N., DeCarli, C., Borowski, B., Gunter, J., Senjem, M., Vemuri, P., Jones, D., Kantarci, K., Ward, C., Koeppe, R. A., Foster, N., Reiman, E. M., Chen, K., Mathis, C., Landau, S., Cairns, N. J., Householder, E., Taylor-Reinwald, L., Lee, V. M. Y., Korecka, M., Figurski, M., Crawford, K., Neu, S., Foroud, T. M., Potkin, S., Shen, L., Faber, K., Kim, S., Nho, K., Thal, L., Frank, R., Buckholtz, N., Albert, M. & Hsiao, J. Jul 20 2015 In : Nature Communications. 6, 7549

Research output: Research - peer-reviewArticle

Polymorphism
Nucleotides
Genomics
Single Nucleotide Polymorphism
polymorphism
Liposomes
Magnetic resonance
Polyethylene glycols
Demonstrations
Imaging techniques
Amides
Protons
Magnetic Resonance Imaging
Brain
Gray Matter
Oxygenation
Magnetic resonance imaging
Blood
Tissue
Oxygen
Noise
Glioblastoma
Principal Component Analysis
Protons
Neoplasms

Optical coherence tomography reflects brain atrophy in multiple sclerosis: A four-year study

Saidha, S., Al-Louzi, O., Ratchford, J. N., Bhargava, P., Oh, J., Newsome, S. D., Prince, J. L., Pham, D., Roy, S., Van Zijl, P., Balcer, L. J., Frohman, E. M., Reich, D. S., Crainiceanu, C. & Calabresi, P. A. Nov 1 2015 In : Annals of Neurology. 78, 5, p. 801-813 13 p.

Research output: Research - peer-reviewArticle

Optical Coherence Tomography
Multiple Sclerosis
Atrophy
Brain
Ganglia
reproducibility
Magnetic Resonance Imaging
Outcome Assessment (Health Care)
biomarkers
clinical trials