Peter C Van Zijl

Professor

1980 …2018
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Research Output 1980 2018

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2018

CEST MRI of sepsis-induced acute kidney injury

Liu, J., Han, Z., Chen, G., Li, Y., Zhang, J., Xu, J., van Zijl, P. C. M., Zhang, S. & Liu, G., Aug 1 2018, In : NMR in Biomedicine. 31, 8, e3942

Research output: Contribution to journalArticle

Acute Kidney Injury
Sepsis
Kidney
Lipopolysaccharides
Cerium

Dynamic glucose enhanced MRI of the placenta in a mouse model of intrauterine inflammation

Wu, D., Xu, J., Lei, J., Mclane, M., van Zijl, P. C. & Burd, I., Sep 1 2018, In : Placenta. 69, p. 86-91 6 p.

Research output: Contribution to journalArticle

Placenta
Inflammation
Glucose
Lipopolysaccharides
Area Under Curve

GlucoCEST imaging with on-resonance variable delay multiple pulse (onVDMP) MRI

Xu, X., Xu, J., Chan, K. W. Y., Liu, J., Liu, H., Li, Y., Chen, L., Liu, G. & van Zijl, P. C. M., Jan 1 2018, (Accepted/In press) In : Magnetic Resonance in Medicine.

Research output: Contribution to journalArticle

Protons
Glucose
Vascular Tissue Neoplasms
Heterografts
Glioma

Low cortical iron and high entorhinal cortex volume promote cognitive functioning in the oldest-old

van Bergen, J. M. G., Li, X., Quevenco, F. C., Gietl, A. F., Treyer, V., Leh, S. E., Meyer, R., Buck, A., Kaufmann, P. A., Nitsch, R. M., van Zijl, P. C. M., Hock, C. & Unschuld, P. G., Apr 1 2018, In : Neurobiology of Aging. 64, p. 68-75 8 p.

Research output: Contribution to journalArticle

Entorhinal Cortex
Amyloid Plaques
Cerebrovascular Disorders
Iron
Magnetic Resonance Imaging
Molecular imaging
Molecular Imaging
Reporter Genes
Gene expression
Magnetic resonance imaging

MRI detection of bacterial brain abscesses and monitoring of antibiotic treatment using bacCEST

Liu, J., Bai, R., Li, Y., Staedtke, V., Zhang, S., van Zijl, P. C. M. & Liu, G., Jan 1 2018, (Accepted/In press) In : Magnetic Resonance in Medicine.

Research output: Contribution to journalArticle

Brain Abscess
Anti-Bacterial Agents
Bacterial Infections
Bacteria
Therapeutics

Phenols as Diamagnetic T2-Exchange Magnetic Resonance Imaging Contrast Agents

Zhang, J., Li, Y., Slania, S., Yadav, N. N., Liu, J., Wang, R., Zhang, J., Pomper, M. G., van Zijl, P. C., Yang, X. & Liu, G., Jan 26 2018, In : Chemistry - A European Journal. 24, 6, p. 1259-1263 5 p.

Research output: Contribution to journalArticle

Hole mobility
Chemical modification
Chemical shift
Enzyme activity
Magnetic resonance imaging

Salicylic Acid-Based Polymeric Contrast Agents for Molecular Magnetic Resonance Imaging of Prostate Cancer

Banerjee, S. R., Song, X., Yang, X., Minn, I., Lisok, A., Chen, Y., Bui, A., Chatterjee, S., Chen, J., vanZijl, P. C. M., Mcmahon, M. T. & Pomper, M. G., Jan 1 2018, (Accepted/In press) In : Chemistry - A European Journal.

Research output: Contribution to journalArticle

Salicylic acid
Hole mobility
Imaging techniques
Magnetic resonance
Protons

Separating fast and slow exchange transfer and magnetization transfer using off-resonance variable-delay multiple-pulse (VDMP) MRI

Chen, L., Xu, X., Zeng, H., Chan, K. W. Y., Yadav, N., Cai, S., Schunke, K. J., Faraday, N., van Zijl, P. C. M. & Xu, J., Jan 1 2018, (Accepted/In press) In : Magnetic Resonance in Medicine.

Research output: Contribution to journalArticle

Protons
Brain
Bovine Serum Albumin
Hair
Glutamic Acid

Simultaneous quantitative susceptibility mapping and Flutemetamol-PET suggests local correlation of iron and β-amyloid as an indicator of cognitive performance at high age

van Bergen, J. M. G., Li, X., Quevenco, F. C., Gietl, A. F., Treyer, V., Meyer, R., Buck, A., Kaufmann, P. A., Nitsch, R. M., van Zijl, P. C. M., Hock, C. & Unschuld, P. G., Jul 1 2018, In : NeuroImage. 174, p. 308-316 9 p.

Research output: Contribution to journalArticle

Amyloid Plaques
Amyloid
Iron
Alzheimer Disease
Clinical Pathology

Whole-brain arteriography and venography: Using improved velocity-selective saturation pulse trains

Li, W., Xu, F., Schär, M., Liu, J., Shin, T., Zhao, Y., van Zijl, P. C. M., Wasserman, B. A., Qiao, Y. & Qin, Q., Apr 1 2018, In : Magnetic Resonance in Medicine. 79, 4, p. 2014-2023 10 p.

Research output: Contribution to journalArticle

Phlebography
Angiography
Brain
Veins
Arteries
2017

Abnormal grey matter arteriolar cerebral blood volume in schizophrenia measured with 3D inflow-based vascular-space-occupancy MRI at 7T

Hua, J., Brandt, A. S., Lee, S. W., Blair, N. I. S., Wu, Y., Lui, S., Patel, J., Faria, A. V., Lim, I. A. L., Unschuld, P. G., Pekar, J. J., Van Zijl, P. C. M., Ross, C. A. & Margolis, R. L., 2017, In : Schizophrenia Bulletin. 43, 3, p. 620-632 13 p.

Research output: Contribution to journalArticle

Blood Vessels
Schizophrenia
Brain
Microvessels
Cerebrovascular Circulation
Cerebrovascular Circulation
Hematocrit
Hemodynamics
Oxygen
Magnetic Resonance Imaging

A dextran-based probe for the targeted magnetic resonance imaging of tumours expressing prostate-specific membrane antigen

Liu, G., Banerjee, S. R., Yang, X., Yadav, N., Lisok, A., Jablonska, A., Xu, J., Li, Y., Pomper, M. G. & Van Zijl, P., Dec 1 2017, In : Nature Biomedical Engineering. 1, 12, p. 977-982 6 p.

Research output: Contribution to journalArticle

Dextran
Magnetic resonance
Antigens
Dextrans
Tumors
Image-Guided Biopsy
Amides
Glioma
Protons
Magnetic Resonance Spectroscopy
Photic Stimulation
Cerebrovascular Circulation
Magnetic Resonance Imaging
Cerebral Blood Volume
Oxygen

Background field removal using a region adaptive kernel for quantitative susceptibility mapping of human brain

Fang, J., Bao, L., Li, X., van Zijl, P. C. M. & Chen, Z., Aug 1 2017, In : Journal of Magnetic Resonance. 281, p. 130-140 11 p.

Research output: Contribution to journalArticle

Brain Mapping
brain
Brain
Tissue
magnetic permeability

Characterization of tumor vascular permeability using natural dextrans and CEST MRI

Li, Y., Qiao, Y., Chen, H., Bai, R., Staedtke, V., Han, Z., Xu, J., Chan, K. W. Y., Yadav, N., Bulte, J. W. M., Zhou, S., van Zijl, P. C. M. & Liu, G., Jan 1 2017, (Accepted/In press) In : Magnetic Resonance in Medicine.

Research output: Contribution to journalArticle

Capillary Permeability
Dextrans
Neoplasms
Injections
Permeability

Consensus statement on current and emerging methods for the diagnosis and evaluation of cerebrovascular disease

Donahue, M. J. , Achten, E. , Cogswell, P. M. , De Leeuw, F. E. , Derdeyn, C. P. , Dijkhuizen, R. M. , Fan, A. P. , Ghaznawi, R. , Heit, J. J. , Ikram, M. A. , Jezzard, P. , Jordan, L. C. , Jouvent, E. , Knutsson, L. , Leigh, R. , Liebeskind, D. S. , Lin, W. , Okell, T. W. , Qureshi, A. I. , Stagg, C. J. & 8 others van Osch, M. J. P., van Zijl, P. C. M., Watchmaker, J. M., Wintermark, M., Wu, O., Zaharchuk, G., Zhou, J. & Hendrikse, J., Jan 1 2017, (Accepted/In press) In : Journal of Cerebral Blood Flow and Metabolism.

Research output: Contribution to journalArticle

Cerebrovascular Disorders
Stroke
Cerebrovascular Circulation
Tissue Survival
Developed Countries

Detection and Quantification of Hydrogen Peroxide in Aqueous Solutions Using Chemical Exchange Saturation Transfer

Ryoo, D., Xu, X., Li, Y., Tang, J. A., Zhang, J., Van Zijl, P. C. M. & Liu, G., Jul 18 2017, In : Analytical Chemistry. 89, 14, p. 7758-7764 7 p.

Research output: Contribution to journalArticle

Saturation (materials composition)
Hydrogen Peroxide
Ion exchange
Nuclear magnetic resonance
Magnetic resonance

Detection of dynamic substrate binding using MRI

Yadav, N. N., Yang, X., Li, Y., Li, W., Liu, G. & Van Zijl, P. C. M., Dec 1 2017, In : Scientific Reports. 7, 1, 10138

Research output: Contribution to journalArticle

Protons
Magnetic Resonance Imaging
Water
Caffeine
Radio

GlucoCEST magnetic resonance imaging in vivo may be diagnostic of acute renal allograft rejection

Kentrup, D., Bovenkamp, P., Busch, A., Schuette-Nuetgen, K., Pawelski, H., Pavenstädt, H., Schlatter, E., Herrmann, K. H., Reichenbach, J. R., Löffler, B., Heitplatz, B., Van Marck, V., Yadav, N. N., Liu, G., van Zijl, P. C. M., Reuter, S. & Hoerr, V., Sep 1 2017, In : Kidney International. 92, 3, p. 757-764 8 p.

Research output: Contribution to journalArticle

Allografts
Magnetic Resonance Imaging
Kidney
Glucose
T-Lymphocytes

Imaging the physiological evolution of the ischemic penumbra in acute ischemic stroke

Leigh, R., Knutsson, L., Zhou, J. & van Zijl, P. C. M., Jan 1 2017, (Accepted/In press) In : Journal of Cerebral Blood Flow and Metabolism.

Research output: Contribution to journalArticle

Cerebrovascular Circulation
Stroke
Infarction
Ischemia
Perfusion
Amides
Protons
Stroke
Proteins
Acidosis

Investigation of the contribution of total creatine to the CEST Z-spectrum of brain using a knockout mouse model

Chen, L., Zeng, H., Xu, X., Yadav, N. N., Cai, S., Puts, N. A., Barker, P. B., Li, T., Weiss, R. G., van Zijl, P. C. M. & Xu, J., Dec 1 2017, In : NMR in Biomedicine. 30, 12, e3834

Research output: Contribution to journalArticle

Creatine
Knockout Mice
Brain
Phosphocreatine
Guanidine

Magnetization Transfer Contrast and Chemical Exchange Saturation Transfer MRI. Features and analysis of the field-dependent saturation spectrum

van Zijl, P. C. M., Lam, W. W., Xu, J., Knutsson, L. & Stanisz, G. J., 2017, (Accepted/In press) In : NeuroImage.

Research output: Contribution to journalArticle

Protons
Water
Magnetic Resonance Spectroscopy
Creatine
Guanidine

Memory performance-related dynamic brain connectivity indicates pathological burden and genetic risk for Alzheimer's disease

Quevenco, F. C., Preti, M. G., Van Bergen, J. M. G., Hua, J., Wyss, M., Li, X., Schreiner, S. J., Steininger, S. C., Meyer, R., Meier, I. B., Brickman, A. M., Leh, S. E., Gietl, A. F., Buck, A., Nitsch, R. M., Pruessmann, K. P., Van Zijl, P. C. M., Hock, C., Van De Ville, D. & Unschuld, P. G., Mar 31 2017, In : Alzheimer's Research and Therapy. 9, 1, 24

Research output: Contribution to journalArticle

Alzheimer Disease
Iron
Brain
Apolipoproteins E
Magnetic Resonance Imaging

Predicting IDH mutation status in grade II gliomas using amide proton transfer-weighted (APTw) MRI

Jiang, S., Zou, T., Eberhart, C. G., Villalobos, M. A. V., Heo, H. Y., Zhang, Y., Wang, Y., Wang, X., Yu, H., Du, Y., van Zijl, P. C. M., Wen, Z. & Zhou, J., Sep 1 2017, In : Magnetic Resonance in Medicine. 78, 3, p. 1100-1109 10 p.

Research output: Contribution to journalArticle

Isocitrate Dehydrogenase
Amides
Glioma
Protons
Mutation

Quantitative assessment of cerebral venous blood T2 in mouse at 11.7T: Implementation, optimization, and age effect

Wei, Z., Xu, J., Liu, P., Chen, L., Li, W., van Zijl, P. & Lu, H., Jan 1 2017, (Accepted/In press) In : Magnetic Resonance in Medicine.

Research output: Contribution to journalArticle

Hyperoxia
Anesthesia
Brain
Dexmedetomidine
Isoflurane

Subject-specific regional measures of water diffusion are associated with impairment in chronic spinal cord injury

Choe, A. S., Sadowsky, C. L., Smith, S. A., van Zijl, P. C. M., Pekar, J. J. & Belegu, V., Aug 1 2017, In : Neuroradiology. 59, 8, p. 747-758 12 p.

Research output: Contribution to journalArticle

Diffusion Tensor Imaging
Spinal Cord Injuries
Water
Wounds and Injuries
Biomarkers
Hemoglobin
Albumins
Hemoglobins
Blood
Erythrocytes
2016

15N Heteronuclear Chemical Exchange Saturation Transfer MRI

Zeng, H., Xu, J., Yadav, N. N., McMahon, M. T., Harden, B., Frueh, D. & Van Zijl, P. C. M., Sep 7 2016, In : Journal of the American Chemical Society. 138, 35, p. 11136-11139 4 p.

Research output: Contribution to journalArticle

Magnetic resonance imaging
Protons
Water
Molecules
Proton transfer

Applying amide proton transfer-weighted MRI to distinguish pseudoprogression from true progression in malignant gliomas

Ma, B., Blakeley, J. O., Hong, X., Zhang, H., Jiang, S., Blair, L., Zhang, Y., Heo, H. Y., Zhang, M., van Zijl, P. C. M. & Zhou, J., Aug 1 2016, In : Journal of Magnetic Resonance Imaging. 44, 2, p. 456-462 7 p.

Research output: Contribution to journalArticle

Amides
Glioma
Protons
Magnetic Resonance Imaging
Research Ethics Committees
Pyramidal Tracts
Brain Stem
Diffusion Magnetic Resonance Imaging
Anisotropy
Staining and Labeling
Restless Legs Syndrome
Iron
Brain
Substantia Nigra
Sleep

CEST-MRI detects metabolite levels altered by breast cancer cell aggressiveness and chemotherapy response

Chan, K. W. Y., Jiang, L., Cheng, M., Wijnen, J. P., Liu, G., Huang, P., van Zijl, P. C. M., Mcmahon, M. T. & Glunde, K., 2016, (Accepted/In press) In : NMR in Biomedicine.

Research output: Contribution to journalArticle

Chemotherapy
Metabolites
Magnetic resonance imaging
Cells
Breast Neoplasms

CEST theranostics: Label-free MR imaging of anticancer drugs

Li, Y., Chen, H., Xu, J., Yadav, N. N., Chan, K. W. Y., Luo, L., McMahon, M. T., Vogelstein, B., Van Zijl, P. C. M., Zhou, S. & Liu, G., 2016, In : Oncotarget. 7, 6, p. 6369-6378 10 p.

Research output: Contribution to journalArticle

Pharmaceutical Preparations
gemcitabine
Folic Acid Antagonists
Neoplasms
Liposomes

Colocalization of cerebral iron with Amyloid beta in Mild Cognitive Impairment

Van Bergen, J. M. G., Li, X., Hua, J., Schreiner, S. J., Steininger, S. C., Quevenco, F. C., Wyss, M., Gietl, A. F., Treyer, V., Leh, S. E., Buck, F., Nitsch, R. M., Pruessmann, K. P., Van Zijl, P. C. M., Hock, C. & Unschuld, P. G., Oct 17 2016, In : Scientific Reports. 6, 35514

Research output: Contribution to journalArticle

Apolipoprotein E4
Amyloid
Iron
Brain
Alzheimer Disease
Internal Carotid Artery
Hematocrit
Carotid Arteries
In Vitro Techniques

Label-free CEST MRI detection of citicoline-liposome drug delivery in ischemic stroke

Liu, H., Jablonska, A., Li, Y., Cao, S., Liu, D., Chen, H., Van Zijl, P. C. M., Bulte, J. W. M., Janowski, M., Walczak, P. & Liu, G., 2016, In : Theranostics. 6, 10, p. 1588-1600 13 p.

Research output: Contribution to journalArticle

Cytidine Diphosphate Choline
Liposomes
Stroke
Pharmaceutical Preparations
Ischemia

Lesion heterogeneity on high-field susceptibility MRI Is associated with multiple sclerosis severity

Harrison, D. M., Li, X., Liu, H., Jones, C. K., Caffo, B., Calabresi, P. A. & Van Zijl, P., Aug 1 2016, In : American Journal of Neuroradiology. 37, 8, p. 1447-1453 7 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Fatigue
Oligodendroglia
Iron
Inflammation

Magnetic susceptibility contrast variations in multiple sclerosis lesions

Li, X., Harrison, D. M., Liu, H., Jones, C. K., Oh, J., Calabresi, P. A. & Van Zijl, P. C. M., Feb 1 2016, In : Journal of Magnetic Resonance Imaging. 43, 2, p. 463-473 11 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Magnetic Resonance Imaging
Masks
Myelin Sheath
Iron

Measurement of arteriolar blood volume in brain tumors using MRI without exogenous contrast agent administration at 7T

Wu, Y., Agarwal, S., Jones, C. K., Webb, A. G., van Zijl, P. C. M., Hua, J. & Pillai, J. J., 2016, (Accepted/In press) In : Journal of Magnetic Resonance Imaging.

Research output: Contribution to journalArticle

Blood Volume
Brain Neoplasms
Contrast Media
Blood Vessels
Perfusion

On-resonance variable delay multipulse scheme for imaging of fast-exchanging protons and semisolid macromolecules

Xu, J., Chan, K. W. Y., Xu, X., Yadav, N., Liu, G. & van Zijl, P. C. M., 2016, (Accepted/In press) In : Magnetic Resonance in Medicine.

Research output: Contribution to journalArticle

Protons
Creatine
Water
Brain
Inositol

Proton chemical exchange saturation transfer (CEST) MRS and MRI

Van Zijl, P. C. M. & Sehgal, A. A., 2016, In : eMagRes. 5, 2, p. 1307-1332 26 p.

Research output: Contribution to journalArticle

Magnetic resonance imaging
Protons
Ion exchange
Water
Metabolites

Quantitative measurement of cerebral blood volume using velocity-selective pulse trains

Liu, D., Xu, F., Lin, D. D., van Zijl, P. C. M. & Qin, Q., 2016, (Accepted/In press) In : Magnetic Resonance in Medicine.

Research output: Contribution to journalArticle

Signal-To-Noise Ratio
Healthy Volunteers
Cerebral Blood Volume
Gray Matter
White Matter

Quantitative susceptibility mapping suggests altered brain iron in premanifest Huntington disease

Van Bergen, J. M. G., Hua, J., Unschuld, P. G., Lim, I. A. L., Jones, C. K., Margolis, R. L., Ross, C. A., Van Zijl, P. C. M. & Li, X., May 1 2016, In : American Journal of Neuroradiology. 37, 5, p. 789-796 8 p.

Research output: Contribution to journalArticle

Huntington Disease
Iron
Caudate Nucleus
Putamen
Brain

Quantitative Susceptibility Mapping Using Structural Feature Based Collaborative Reconstruction (SFCR) in the Human Brain

Bao, L., Li, X., Cai, C., Chen, Z. & Van Zijl, P. C. M., Sep 1 2016, In : IEEE Transactions on Medical Imaging. 35, 9, p. 2040-2050 11 p., 7438877

Research output: Contribution to journalArticle

Brain
Supine Position
Artifacts
Noise
Anatomy

Quantitative theory for the longitudinal relaxation time of blood water

Li, W., Grgac, K., Huang, A., Yadav, N., Qin, Q. & van Zijl, P. C. M., Jul 1 2016, In : Magnetic Resonance in Medicine. 76, 1, p. 270-281 12 p.

Research output: Contribution to journalArticle

Water
Methemoglobin
Hemoglobins
Hematocrit
Albumins

Screening CEST contrast agents using ultrafast CEST imaging

Xu, X., Yadav, N. N., Song, X., McMahon, M. T., Jerschow, A., Van Zijl, P. C. M. & Xu, J., Apr 1 2016, In : Journal of Magnetic Resonance. 265, p. 224-229 6 p.

Research output: Contribution to journalArticle

Contrast Media
Screening
screening
saturation
Imaging techniques