1981 …2018
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Research Output 1981 2018

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Article
2018
Aquaglyceroporins
Merozoites
Malaria
Parasites
Liver
2017

Driving mosquito refractoriness to Plasmodium falciparum with engineered symbiotic bacteria

Wang, S., Dos-Santos, A. L. A., Huang, W., Liu, K. C., Oshaghi, M. A., Wei, G., Agre, P. & Jacobs-Lorena, M., Sep 29 2017, In : Science. 357, 6358, p. 1399-1402 4 p.

Research output: Contribution to journalArticle

Plasmodium falciparum
Culicidae
Bacteria
Serratia
Ovary
2016

Aquaglyceroporin function in the malaria mosquito Anopheles gambiae

Liu, K., Tsujimoto, H., Huang, Y., Rasgon, J. L. & Agre, P., Oct 1 2016, In : Biology of the Cell. 108, 10, p. 294-305 12 p.

Research output: Contribution to journalArticle

Aquaglyceroporins
Anopheles gambiae
Culicidae
Malaria
Aquaporins

Training the next generation of biomedical investigators in glycosciences

Agre, P. , Bertozzi, C. , Bissell, M. , Campbell, K. P. , Cummings, R. D. , Desai, U. R. , Estes, M. , Flotte, T. , Fogleman, G. , Gage, F. , Ginsburg, D. , Gordon, J. I. , Hart, G. , Hascall, V. , Kiessling, L. , Kornfeld, S. , Lowe, J. , Magnani, J. , Mahal, L. K. , Medzhitov, R. & 8 others Roberts, R. J., Sackstein, R., Sarkar, R., Schnaar, R., Schwartz, N., Varki, A., Walt, D. & Weissman, I., Feb 1 2016, In : Journal of Clinical Investigation. 126, 2, p. 405-408 4 p.

Research output: Contribution to journalArticle

Research Personnel
National Heart, Lung, and Blood Institute (U.S.)
Education
Group Processes
Research
2014

Foreword to 2014 Aquaporins special issue

Agre, P., 2014, In : Biochimica et Biophysica Acta - General Subjects. 1840, 5, p. 1466-1467 2 p.

Research output: Contribution to journalArticle

21st Century History
20th Century History
Interdisciplinary Communication
Diffusion of Innovation
Narration
2013
Anopheles gambiae
Trehalose
Plasmodium falciparum
Culicidae
Malaria

Organ-Specific Splice Variants of Aquaporin Water Channel AgAQP1 in the Malaria Vector Anopheles gambiae

Tsujimoto, H., Liu, K., Linser, P. J., Agre, P. & Rasgon, J. L., Sep 16 2013, In : PLoS One. 8, 9, e75888

Research output: Contribution to journalArticle

Aquaporin 1
Anopheles gambiae
Aquaporins
aquaporins
Culicidae

Protective role of brain water channel AQP4 in murine cerebral malaria

Promeneur, D., Lunde, L. K., Amiry-Moghaddam, M. & Agre, P., Jan 15 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 3, p. 1035-1040 6 p.

Research output: Contribution to journalArticle

Aquaporin 4
Cerebral Malaria
Aquaporins
Brain
Plasmodium berghei
2011
Aquaporin 1
Anopheles gambiae
Aquaporins
Humidity
Malaria

Effects of Acetaldehyde on Hepatocyte Glycerol Uptake and Cell Size: Implication of Aquaporin 9

Potter, J. J., Koteish, A., Hamilton, J., Liu, X., Liu, K., Agre, P. & Mezey, E., May 2011, In : Alcoholism: Clinical and Experimental Research. 35, 5, p. 939-945 7 p.

Research output: Contribution to journalArticle

Aquaporins
Acetaldehyde
Cell Size
Glycerol
Hepatocytes

Life on the river of science

Agre, P., Jan 28 2011, In : Science. 331, 6016, p. 416-421 6 p.

Research output: Contribution to journalArticle

21st Century History
20th Century History
poliomyelitis
educational development
Aquaporin 1

Malaria antifolate resistance with contrasting Plasmodium falciparum dihydrofolate reductase (DHFR) polymorphisms in humans and Anopheles mosquitoes

Mharakurwa, S., Kumwenda, T., Mkulama, M. A. P., Musapa, M., Chishimba, S., Shiff, C. J., Sullivan, D. J., Thuma, P. E., Liu, K. & Agre, P., Nov 15 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 46, p. 18796-18801 6 p.

Research output: Contribution to journalArticle

Folic Acid Antagonists
Tetrahydrofolate Dehydrogenase
Anopheles
Plasmodium falciparum
Culicidae
2010

Advancing science, promoting peace

Agre, P. C. & Turekian, V., Aug 25 2010, In : Science Translational Medicine. 2, 46, 46ed7

Research output: Contribution to journalArticle

International Cooperation
Medical Societies

Editorial: Bridging science and society

Agre, P. & Leshner, A. I., Feb 19 2010, In : Science. 327, 5968, p. 921 1 p.

Research output: Contribution to journalArticle

Religion and Science
Public Opinion
Sociology
Community Participation

The family naturalist

Agre, P., Oct 14 2010, In : Nature. 467, 7317 SUPPL.

Research output: Contribution to journalArticle

Research Peer Review
Interdisciplinary Communication
Nobel Prize
Happiness
Aquaporins
2009

Aquaporin 6 binds calmodulin in a calcium-dependent manner

Rabaud, N. E., Song, L., Wang, Y., Agre, P., Yasui, M. & Carbrey, J. M., May 22 2009, In : Biochemical and Biophysical Research Communications. 383, 1, p. 54-57 4 p.

Research output: Contribution to journalArticle

Aquaporin 6
Calmodulin
Calcium
Binding Sites
Anions

Discovery of the aquaporins and development of the field

Carbrey, J. M. & Agre, P., 2009, In : Handbook of Experimental Pharmacology. 190, p. 3-28 26 p.

Research output: Contribution to journalArticle

Aquaporins
Water
Mammals
Blood Group Antigens
Permeability

Osteoclast differentiation and function in aquaglyceroporin AQP9-null mice

Liu, Y., Song, L., Wang, Y., Rojek, A., Nielsen, S., Agre, P. & Carbrey, J. M., 2009, In : Biology of the Cell. 101, 3, p. 133-140 8 p.

Research output: Contribution to journalArticle

Aquaglyceroporins
Osteoclasts
Macrophages
Bone and Bones
X-Ray Microtomography

Reduced arsenic clearance and increased toxicity in aquaglyceroporin-9-null mice

Carbrey, J. M., Song, L., Zhou, Y., Yoshinaga, M., Rojek, A., Wang, Y., Liu, Y., Lujan, H. L., DiCarlo, S. E., Nielsen, S., Rosen, B. P., Agre, P. & Mukhopadhyay, R., Sep 15 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 37, p. 15956-15960 5 p.

Research output: Contribution to journalArticle

Aquaglyceroporins
Arsenic
Liver
Injections
Bradycardia

Targeted disruption of the Cl -/HCO 3 - exchanger Ae2 results in osteopetrosis in mice

Josephsen, K., Praetorius, J., Frische, S., Gawenis, L. R., Kwon, T. H., Agre, P., Nielsen, S. & Fejerskov, O., Feb 3 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 5, p. 1638-1641 4 p.

Research output: Contribution to journalArticle

Osteopetrosis
Osteoclasts
Bone Resorption
Antiporters
Bone and Bones

The 2009 lindau Nobel laureate meeting: Peter Agre, Chemistry 2003

Agre, P. Dec 2009 In : Journal of Visualized Experiments. 34, e1565

Research output: Contribution to journalArticle

Aquaporins
Proteins
Nobel Prize
Cell membranes
Water
2008

Erratum: Mercury chloride decreases the water permeability of aquaporin-4-reconstituted proteoliposomes (Biology of the Cell (2008) vol. 100 (6) (355-363))

Yukutake, Y., Tsuji, S., Hirano, Y., Adachi, T., Takahashi, T., Fujihara, K., Agre, P., Yasui, M. & Suematsu, M., Sep 2008, In : Biology of the Cell. 100, 9, p. 561 1 p.

Research output: Contribution to journalArticle

Aquaporin 4
Mercury
Cell Biology
Chlorides
Permeability

Foreword

Agre, P., Apr 15 2008, In : Unknown Journal.

Research output: Contribution to journalArticle

Mercury chloride decreases the water permeability of aquaporin-4-reconstituted proteoliposomes

Yukutake, Y., Tsuji, S., Hirano, Y., Adachi, T., Takahashi, T., Fujihara, K., Agre, P., Yasui, M. & Suematsu, M., Jun 2008, In : Biology of the Cell. 100, 6, p. 355-363 9 p.

Research output: Contribution to journalArticle

Aquaporin 4
Mercury
Cysteine
Chlorides
Permeability

Proteomic analysis of lithium-induced nephrogenic diabetes insipidus: Mechanisms for aquaporin 2 down-regulation and cellular proliferation

Nielsen, J., Hoffert, J. D., Knepper, M. A., Agre, P., Nielsen, S. & Fenton, R. A., Mar 4 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 9, p. 3634-3639 6 p.

Research output: Contribution to journalArticle

Aquaporin 2
Nephrogenic Diabetes Insipidus
Lithium
Proteomics
Down-Regulation
2007

Aquaglyceroporin PbAQP during intraerythrocytic development of the malaria parasite Plasmodium berghei

Promeneur, D., Liu, Y., Maciel, J., Agre, P., King, L. S. & Kumar, N., Feb 13 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 7, p. 2211-2216 6 p.

Research output: Contribution to journalArticle

Aquaglyceroporins
Plasmodium berghei
Malaria
Parasites
Glycerol

Aquaporin 9 is the major pathway for glycerol uptake by mouse erythrocytes, with implications for malarial virulence

Liu, Y., Promeneur, D., Rojek, A., Kumar, N., Frøkiær, J., Nielsen, S., King, L. S., Agre, P. & Carbrey, J. M., Jul 24 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 30, p. 12560-12564 5 p.

Research output: Contribution to journalArticle

Aquaporins
Glycerol
Virulence
Erythrocytes
Aquaglyceroporins

Defective glycerol metabolism in aquaporin 9 (AQP9) knockout mice

Rojek, A. M., Skowronski, M. T., Füchtbauer, E. M., Füchtbauer, A. C., Fenton, R. A., Agre, P., Frøkiær, J. & Nielsen, S., Feb 27 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 9, p. 3609-3614 6 p.

Research output: Contribution to journalArticle

Aquaporins
Knockout Mice
Glycerol
Blood Glucose
Aquaglyceroporins

Fast and selective ammonia transport by aquaporin-8

Saparov, S. M., Liu, K., Agre, P. & Pohl, P., Feb 23 2007, In : Journal of Biological Chemistry. 282, 8, p. 5296-5301 6 p.

Research output: Contribution to journalArticle

Ammonia
Permeability
Aquaporins
Ammonium Compounds
Membranes

Functional analysis of the aquaporin gene family in Caenorhabditis elegans

Huang, C. G., Lamitina, T., Agre, P. & Strange, K., May 2007, In : American Journal of Physiology - Cell Physiology. 292, 5

Research output: Contribution to journalArticle

Functional analysis
Aquaporins
Caenorhabditis elegans
Genes
Animals

Molecular cloning and characterization of mouse aquaporin 6

Nagase, H., Ågren, J., Saito, A., Liu, K., Agre, P., Hazama, A. & Yasui, M., Jan 5 2007, In : Biochemical and Biophysical Research Communications. 352, 1, p. 12-16 5 p.

Research output: Contribution to journalArticle

Aquaporin 6
Cloning
Molecular Cloning
Rats
Complementary DNA

Regulation and dysregulation of aquaporins in water balance disorders

Nielsen, S., Kwon, T. H., Frøkiær, J. & Agre, P., Jan 2007, In : Journal of Internal Medicine. 261, 1, p. 53-64 12 p.

Research output: Contribution to journalArticle

Aquaporins
Aquaporin 1
Water
Kidney
Aquaporin 4

The Israeli-Palestinian Science Organization [1]

Wiesel, T., Agre, P., Arrow, K. J., Atiyah, M., Brézin, E., Charfi, F. F., Cohen-Tannoudji, C., Daar, A., Jacob, F., Kahneman, D., Yuan, T. L., Nicolaisen, I., Nusseibeh, S., Reuter, H., Shoham, Y., Sulston, J., Walzer, M. & Yaari, M., Jan 5 2007, In : Science. 315, 5808, p. 39 1 p.

Research output: Contribution to journalArticle

2006

Aquaporin-11: A channel protein lacking apparent transport function expressed in brain

Gorelick, D. A., Praetorius, J., Tsunenari, T., Nielsen, S. & Agre, P., May 1 2006, In : BMC Biochemistry. 7, 14

Research output: Contribution to journalArticle

Aquaporins
Brain
Proteins
Aquaglyceroporins
Purkinje Cells

Aquaporin water channels: from atomic structure to clinical medicine

Agre, P. Dec 2006 In : Nanomedicine: Nanotechnology, Biology, and Medicine. 2, 4, p. 266-267 2 p.

Research output: Contribution to journalArticle

Aquaporins
Clinical Medicine

Co-axial association of recombinant eye lens aquaporin-0 observed in loosely packed 3D crystals

Palanivelu, D. V., Kozono, D. E., Engel, A., Suda, K., Lustig, A., Agre, P. & Schirmer, T., Jan 27 2006, In : Journal of Molecular Biology. 355, 4, p. 605-611 7 p.

Research output: Contribution to journalArticle

Crystalline Lens
Membrane Proteins
Membranes
Ultracentrifugation
Detergents

Determinants of AQP6 trafficking to intracellular sites versus the plasma membrane in transfected mammalian cells

Beitz, E., Liu, K., Ikeda, M., Guggino, W. B., Agre, P. & Yasui, M., Feb 2006, In : Biology of the Cell. 98, 2, p. 101-109 9 p.

Research output: Contribution to journalArticle

Green Fluorescent Proteins
Cell Membrane
Hemagglutinins
Water Movements
Intracellular Membranes

Isolation of C. elegans deletion mutants following ENU mutagenesis and thermostable restriction enzyme PCR screening

Huang, C. G., Agre, P., Strange, K. & Lamitina, T., Jan 2006, In : Applied Biochemistry and Biotechnology - Part B Molecular Biotechnology. 32, 1, p. 83-86 4 p.

Research output: Contribution to journalArticle

Mutagenesis
Polymerase chain reaction
Screening
Enzymes
Genes

Purification and functional characterization of aquaporin-8

Liu, K., Nagase, H., Huang, C. G., Calamita, G. & Agre, P., Mar 2006, In : Biology of the Cell. 98, 3, p. 153-161 9 p.

Research output: Contribution to journalArticle

Oocytes
Ammonium Compounds
Water
Urea
Mercuric Chloride

Temporary loss of perivascular aquaporin-4 in neocortex after transient middle cerebral artery occlusion in mice

Frydenlund, D. S., Bhardwaj, A., Otsuka, T., Mylonakou, M. N., Yasumura, T., Davidson, K. G. V., Zeynalov, E., Skare, Ø., Laake, P., Haug, F. M., Rash, J. E., Agre, P., Ottersen, O. P. & Amiry-Moghaddam, M., Sep 5 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 36, p. 13532-13536 5 p.

Research output: Contribution to journalArticle

Aquaporin 4
Middle Cerebral Artery Infarction
Neocortex
Reperfusion
Corpus Striatum

The aquaporin water channels

Agre, P., Mar 2006, In : Proceedings of the American Thoracic Society. 3, 1, p. 5-13 9 p.

Research output: Contribution to journalArticle

Biological Transport
Cell Membrane Permeability
Aquaporins
Body Water
2005

Aquaporin expression and freeze tolerance in Candida albicans

Tanghe, A., Carbrey, J. M., Agre, P., Thevelein, J. M. & Van Dijck, P., Oct 2005, In : Applied and Environmental Microbiology. 71, 10, p. 6434-6437 4 p.

Research output: Contribution to journalArticle

freeze tolerance
Aquaporins
aquaporins
Candida albicans
cold tolerance

Aquaporin water channels

Agre, P., Jul 2005, In : Bioscience Reports. 24, 3, p. 127-163 37 p.

Research output: Contribution to journalArticle

Aquaporins
Sweden
Airports
Clothing
Industry

Conversion of aquaporin 6 from an anion channel to a water-selective channel by a single amino acid substitution

Liu, K., Kozono, D., Kato, Y., Agre, P., Hazama, A. & Yasui, M., Feb 8 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 6, p. 2192-2197 6 p.

Research output: Contribution to journalArticle

Aquaporin 6
Aquaporins
Amino Acid Substitution
Anions
Oocytes

Identification of AQP5 in lipid rafts and its translocation to apical membranes by activation of M3 mAChRs in interlobular ducts of rat parotid gland

Ishikawa, Y., Yuan, Z., Inoue, N., Skowronski, M. T., Nakae, Y., Shono, M., Cho, G., Yasui, M., Agre, P. & Nielsen, S., Nov 2005, In : American Journal of Physiology - Cell Physiology. 289, 5 58-5

Research output: Contribution to journalArticle

Aquaporin 5
Parotid Gland
Ducts
Rats
Chemical activation

Loss of perivascular aquaporin 4 may underlie deficient water and K + homeostasis in the human epileptogenic hippocampus

Eid, T., Lee, T. S. W., Thomas, M. J., Amiry-Moghaddam, M., Bjørnsen, L. P., Spencer, D. D., Agre, P., Ottersen, O. P. & De Lanerolle, N. C., Jan 25 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 4, p. 1193-1198 6 p.

Research output: Contribution to journalArticle

Aquaporin 4
Temporal Lobe Epilepsy
Hippocampus
Homeostasis
Dystrophin

Membrane water transport and aquaporins: Looking back

Agre, P., Jun 2005, In : Biology of the Cell. 97, 6, p. 355-356 2 p.

Research output: Contribution to journalArticle

20th Century History
Aquaporins
Lipid Bilayers
Cell Membrane
Lipids

Structural basis for conductance by the archaeal aquaporin AqpM at 1.68 Å

Lee, J. K., Kozono, D., Remis, J., Kitagawa, Y., Agre, P. & Stroud, R. M., Dec 27 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 52, p. 18932-18937 6 p.

Research output: Contribution to journalArticle

Aquaporins
Aquaglyceroporins
Methanobacteriaceae
Crystallography
Water

Using ethics to fight bioterrorism [1] (multiple letters)

Frankel, M. S., Li, L., Green, S. K., Rath, J., Jank, B., Perman, B., Agre, P. C., Altman, S., Curl, R. F., Wiesel, T. N., West-Eberhard, M. J., Somerville, M. & Atlas, R., Aug 12 2005, In : Science. 309, 5737, p. 1012-1017 6 p.

Research output: Contribution to journalArticle