Peter B Barker

Professor

1984 …2018
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Research Output 1984 2018

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Article
2018
Neuropsychological Tests
HIV Infections
Parietal Lobe
HIV
Glutamic Acid

A convolutional neural network to filter artifacts in spectroscopic MRI

Gurbani, S. S., Schreibmann, E., Maudsley, A. A., Cordova, J. S., Soher, B. J., Poptani, H., Verma, G., Barker, P. B., Shim, H. & Cooper, L. A. D. Jan 1 2018 (Accepted/In press) In : Magnetic Resonance in Medicine.

Research output: Contribution to journalArticle

Artifacts
Ionizing Radiation
Contrast Media
Area Under Curve
Protons

AutoVOI: Real-time automatic prescription of volume-of-interest for single voxel spectroscopy

Park, Y. W., Deelchand, D. K., Joers, J. M., Hanna, B., Berrington, A., Gillen, J. S., Kantarci, K., Soher, B. J., Barker, P. B., Park, H., Öz, G. & Lenglet, C. Jan 1 2018 (Accepted/In press) In : Magnetic resonance in medicine.

Research output: Contribution to journalArticle

Prescriptions
Spectrum Analysis
Atlases
Brain
Cerebrum

Effects of Aging on the Human Brain: A Proton and Phosphorus MR Spectroscopy Study at 3T

Schmitz, B., Wang, X., Barker, P. B., Pilatus, U., Bronzlik, P., Dadak, M., Kahl, K. G., Lanfermann, H. & Ding, X. Q. Jan 1 2018 (Accepted/In press) In : Journal of Neuroimaging.

Research output: Contribution to journalArticle

Phosphorus
Protons
Magnetic Resonance Spectroscopy
Adenosine Triphosphate
Brain

Effects of eddy currents on selective spectral editing experiments at 3T

Oeltzschner, G., Snoussi, K., Puts, N. A., Mikkelsen, M., Harris, A. D., Pradhan, S., Tsapkini, K., Schär, M., Barker, P. B. & Edden, R. A. E. Mar 1 2018 In : Journal of Magnetic Resonance Imaging. 47, 3, p. 673-681 9 p.

Research output: Contribution to journalArticle

gamma-Aminobutyric Acid
Water
Magnetic Resonance Spectroscopy

Multivoxel proton magnetic resonance spectroscopy in facioscapulohumeral muscular dystrophy

Leung, D. G., Wang, X., Barker, P. B., Carrino, J. A. & Wagner, K. R. Jun 1 2018 In : Muscle and Nerve. 57, 6, p. 958-963 6 p.

Research output: Contribution to journalArticle

Facioscapulohumeral Muscular Dystrophy
Creatine
Muscle Strength
Muscles
Thigh
Gadolinium
Contrast Media

Simultaneous editing of GABA and glutathione at 7T using semi-LASER localization

Saleh, M. G., Mikkelsen, M., Oeltzschner, G., Chan, K. L., Berrington, A., Barker, P. B. & Edden, R. A. E. Jan 1 2018 (Accepted/In press) In : Magnetic Resonance in Medicine.

Research output: Contribution to journalArticle

gamma-Aminobutyric Acid
Glutathione
Spectrum Analysis
Healthy Volunteers
2017

1H-MRS processing parameters affect metabolite quantification: The urgent need for uniform and transparent standardization

Bhogal, A. A., Schür, R. R., Houtepen, L. C., van de Bank, B., Boer, V. O., Marsman, A., Barker, P. B., Scheenen, T. W. J., Wijnen, J. P., Vinkers, C. H. & Klomp, D. W. J. 2017 (Accepted/In press) In : NMR in Biomedicine.

Research output: Contribution to journalArticle

Creatine
Metabolites
Phosphocreatine
Standardization
Software
Image-Guided Biopsy
Amides
Glioma
Protons
Magnetic Resonance Spectroscopy

A simultaneous multi-slice selective J-resolved experiment for fully resolved scalar coupling information

Zeng, Q., Lin, L., Chen, J., Lin, Y., Barker, P. B. & Chen, Z. Sep 1 2017 In : Journal of Magnetic Resonance. 282, p. 27-31 5 p.

Research output: Contribution to journalArticle

Protons
scalars
Molecular Structure
Molecular structure
protons

Big GABA: Edited MR spectroscopy at 24 research sites

Mikkelsen, M. , Barker, P. B. , Bhattacharyya, P. K. , Brix, M. K. , Buur, P. F. , Cecil, K. M. , Chan, K. L. , Chen, D. Y. T. , Craven, A. R. , Cuypers, K. , Dacko, M. , Duncan, N. W. , Dydak, U. , Edmondson, D. A. , Ende, G. , Ersland, L. , Gao, F. , Greenhouse, I. , Harris, A. D. , He, N. & 30 others Heba, S., Hoggard, N., Hsu, T. W., Jansen, J. F. A., Kangarlu, A., Lange, T., Lebel, R. M., Li, Y., Lin, C. Y. E., Liou, J. K., Lirng, J. F., Liu, F., Ma, R., Maes, C., Moreno-Ortega, M., Murray, S. O., Noah, S., Noeske, R., Noseworthy, M. D., Oeltzschner, G., Prisciandaro, J. J., Puts, N. A. J., Roberts, T. P. L., Sack, M., Sailasuta, N., Saleh, M. G., Schallmo, M. P., Simard, N., Zipunnikov, V. & Edden, R. A. E. Oct 1 2017 In : NeuroImage. 159, p. 32-45 14 p.

Research output: Contribution to journalArticle

gamma-Aminobutyric Acid
Magnetic Resonance Spectroscopy
Research
Multilevel Analysis
Benchmarking

Dual-volume excitation and parallel reconstruction for J-difference-edited MR spectroscopy

Oeltzschner, G., Puts, N. A. J., Chan, K. L., Boer, V. O., Barker, P. B. & Edden, R. A. E. Jan 1 2017 In : Magnetic Resonance in Medicine. 77, 1, p. 16-22 7 p.

Research output: Contribution to journalArticle

gamma-Aminobutyric Acid
Magnetic Resonance Spectroscopy
Glutathione
Signal-To-Noise Ratio
Healthy Volunteers

Frequency-Dependent Changes in the Amplitude of Low-Frequency Fluctuations in Mild Cognitive Impairment with Mild Depression

Li, Y., Jing, B., Liu, H., Li, Y., Gao, X., Li, Y., Mu, B., Yu, H., Cheng, J., Barker, P. B., Wang, H. & Han, Y. 2017 In : Journal of Alzheimer's Disease. 58, 4, p. 1175-1187 13 p.

Research output: Contribution to journalArticle

Depression
Magnetic Resonance Imaging
Parietal Lobe
Cognitive Dysfunction
Parahippocampal Gyrus

Investigation of the contribution of total creatine to the CEST Z-spectrum of brain using a knockout mouse model

Chen, L., Zeng, H., Xu, X., Yadav, N. N., Cai, S., Puts, N. A., Barker, P. B., Li, T., Weiss, R. G., van Zijl, P. C. M. & Xu, J. Dec 1 2017 In : NMR in Biomedicine. 30, 12, e3834

Research output: Contribution to journalArticle

Creatine
Knockout Mice
Brain
Phosphocreatine
Guanidine

Normalizing data from GABA-edited MEGA-PRESS implementations at 3 Tesla

Harris, A. D., Puts, N. A. J., Wijtenburg, S. A., Rowland, L. M., Mikkelsen, M., Barker, P. B., Evans, C. J. & Edden, R. A. E. Oct 1 2017 In : Magnetic Resonance Imaging. 42, p. 8-15 8 p.

Research output: Contribution to journalArticle

Macromolecules
gamma-Aminobutyric Acid
Magnetic resonance imaging
Standardization
Creatine

Simultaneous detection of glutathione and lactate using spectral editing at 3 T

Chan, K. L., Snoussi, K., Edden, R. A. E. & Barker, P. B. Dec 1 2017 In : NMR in Biomedicine. 30, 12, e3800

Research output: Contribution to journalArticle

Glutathione
Lactic Acid
Spectrum Analysis
Spectroscopy
Metabolites

Simultaneous measurement of Aspartate, NAA, and NAAG using HERMES spectral editing at 3 Tesla

Chan, K. L., Saleh, M. G., Oeltzschner, G., Barker, P. B. & Edden, R. A. E. Feb 10 2017 (Accepted/In press) In : NeuroImage.

Research output: Contribution to journalArticle

Aspartic Acid
Glutamine
gamma-Aminobutyric Acid
Glutathione
N-acetyl-1-aspartylglutamic acid

Spatial Hadamard encoding of J-edited spectroscopy using slice-selective editing pulses

Chan, K. L., Oeltzschner, G., Schär, M., Barker, P. B. & Edden, R. A. E. 2017 (Accepted/In press) In : NMR in Biomedicine.

Research output: Contribution to journalArticle

gamma-Aminobutyric Acid
Spectrum Analysis
Spectroscopy
Metabolites
Glutathione
2016
Restless Legs Syndrome
Iron
Brain
Substantia Nigra
Sleep

Correlates of virtual navigation performance in older adults

Korthauer, L. E., Nowak, N. T., Moffat, S. D., An, Y., Rowland, L. M., Barker, P. B., Resnick, S. M. & Driscoll, I. Mar 1 2016 In : Neurobiology of Aging. 39, p. 118-127 10 p.

Research output: Contribution to journalArticle

Water
Learning
Anisotropy
Task Performance and Analysis
Prefrontal Cortex

Decoupling of Brain Temperature and Glutamate in Recent Onset of Schizophrenia: A 7T Proton Magnetic Resonance Spectroscopy Study

Posporelis, S., Coughlin, J. M., Marsman, A., Pradhan, S., Tanaka, T., Wang, H., Varvaris, M., Ward, R., Higgs, C., Edwards, J. A., Ford, C. N., Kim, P. K., Lloyd, A. M., Edden, R. A. E., Schretlen, D. J., Cascella, N. G., Barker, P. B. & Sawa, A. Dec 27 2016 (Accepted/In press) In : Biological Psychiatry: Cognitive Neuroscience and Neuroimaging.

Research output: Contribution to journalArticle

Glutamic Acid
Schizophrenia
Temperature
Brain
Synaptic Transmission

Echo time optimization for J-difference editing of glutathione at 3T

Chan, K. L., Puts, N. A. J., Snoussi, K., Harris, A. D., Barker, P. B. & Edden, R. A. E. 2016 (Accepted/In press) In : Magnetic Resonance in Medicine.

Research output: Contribution to journalArticle

Glutathione
Healthy Volunteers

Elevated brain lactate in schizophrenia: a 7 T magnetic resonance spectroscopy study

Rowland, L. M., Pradhan, S., Korenic, S., Wijtenburg, S. A., Hong, L. E., Edden, R. A. & Barker, P. B. Nov 29 2016 In : Translational psychiatry. 6, 11, p. e967

Research output: Contribution to journalArticle

Gyrus Cinguli
Psychotic Disorders
Case-Control Studies
Young Adult
Lactic Acid

GABA quantitation using MEGA-PRESS: Regional and hemispheric differences

Grewal, M., Dabas, A., Saharan, S., Barker, P. B., Edden, R. A. E. & Mandal, P. K. 2016 (Accepted/In press) In : Journal of Magnetic Resonance Imaging.

Research output: Contribution to journalArticle

gamma-Aminobutyric Acid
Occipital Lobe
Parietal Lobe
Frontal Lobe
Linear Models

HERMES: Hadamard encoding and reconstruction of MEGA-edited spectroscopy

Chan, K. L., Puts, N. A. J., Schär, M., Barker, P. B. & Edden, R. A. E. Jul 1 2016 In : Magnetic Resonance in Medicine. 76, 1, p. 11-19 9 p.

Research output: Contribution to journalArticle

Spectrum Analysis
N-acetyl-1-aspartylglutamic acid
N-acetylaspartate
Aspartic Acid
Glutathione

Prospective frequency correction for macromolecule-suppressed GABA editing at 3T

Edden, R. A. E., Oeltzschner, G., Harris, A. D., Puts, N. A. J., Chan, K. L., Boer, V. O., Schär, M. & Barker, P. B. 2016 (Accepted/In press) In : Journal of Magnetic Resonance Imaging.

Research output: Contribution to journalArticle

gamma-Aminobutyric Acid
Water

Quantifying spectra in the frequency domain

Pradhan, S., Soher, B. J. & Barker, P. B. 2016 In : eMagRes. 5, 2, p. 1247-1256 10 p.

Research output: Contribution to journalArticle

Magnetic resonance
Magnetic Resonance Spectroscopy
Data acquisition
Curve fitting
Metabolites

The MRI Helium Crisis: Past and Future

Mahesh, M. & Barker, P. B. Dec 1 2016 In : Journal of the American College of Radiology. 13, 12, p. 1536-1537 2 p.

Research output: Contribution to journalArticle

Refrigeration
Helium
Conservation of Natural Resources
Magnetic Resonance Imaging
2015
Globus Pallidus
Neuroimaging
gamma-Aminobutyric Acid
Energy Metabolism
Succinate-Semialdehyde Dehydrogenase

Age-related changes in anterior cingulate cortex glutamate in schizophrenia: A 1H MRS Study at 7Tesla

Brandt, A. S., Unschuld, P. G., Pradhan, S., Lim, I. A. L., Churchill, G., Harris, A. D., Hua, J., Barker, P. B., Ross, C. A., van Zijl, P. C. M., Edden, R. A. E. & Margolis, R. L. Dec 25 2015 (Accepted/In press) In : Schizophrenia Research.

Research output: Contribution to journalArticle

Gyrus Cinguli
Glutamic Acid
Schizophrenia
Magnetic Resonance Spectroscopy
Glutamine

Comparison of brain gray and white matter macromolecule resonances at 3 and 7 Tesla

Snoussi, K., Gillen, J. S., Horska, A., Puts, N. A. J., Pradhan, S., Edden, R. A. E. & Barker, P. B. Sep 1 2015 In : Magnetic Resonance in Medicine. 74, 3, p. 607-613 7 p.

Research output: Contribution to journalArticle

Gyrus Cinguli
Protons
Brain
Water
Healthy Volunteers

Comparison of single voxel brain MRS AT 3T and 7T using 32-channel head coils

Pradhan, S., Bonekamp, S., Gillen, J. S., Rowland, L. M., Wijtenburg, S. A., Edden, R. A. E. & Barker, P. B. Oct 1 2015 In : Magnetic Resonance Imaging. 33, 8, p. 1013-1018 6 p.

Research output: Contribution to journalArticle

Magnetic resonance spectroscopy
Signal-To-Noise Ratio
Metabolites
Brain
Magnetic Resonance Spectroscopy

Co-registration of magnetic resonance spectroscopy and transcranial magnetic stimulation

Hone-Blanchet, A., Salas, R. E., Celnik, P., Kalloo, A., Schar, M., Puts, N. A. J., Harris, A. D., Barker, P. B., Fecteau, S., Earley, C. J., Allen, R. P. & Edden, R. A. Mar 5 2015 In : Journal of Neuroscience Methods. 242, p. 52-57 6 p.

Research output: Contribution to journalArticle

Transcranial Magnetic Stimulation
Magnetic Resonance Spectroscopy
Neurotransmitter Agents
Motor Cortex
Hand

Cortical brain atrophy and intra-individual variability in neuropsychological test performance in HIV disease

Hines, L. J., Miller, E. N., Hinkin, C. H., Alger, J. R., Barker, P., Goodkin, K., Martin, E. M., Maruca, V., Ragin, A., Sacktor, N., Sanders, J., Selnes, O., Becker, J. T. & For The Multicenter Aids Cohort Study, T. M. A. C. S. Aug 25 2015 (Accepted/In press) In : Brain Imaging and Behavior.

Research output: Contribution to journalArticle

Neuropsychological Tests
Atrophy
Parietal Lobe
HIV
Brain

Decoupling of N-acetyl-aspartate and glutamate within the dorsolateral prefrontal cortex in schizophrenia

Coughlin, J. M., Tanaka, T., Marsman, A., Wang, H., Bonekamp, S., Kim, P. K., Higgs, C., Varvaris, M., Edden, R., Pomper, M., Schretlen, D., Barker, P. B. & Sawa, A. 2015 In : Current Molecular Medicine. 15, 2, p. 176-183 8 p.

Research output: Contribution to journalArticle

Creatine
Prefrontal Cortex
Glutamic Acid
Schizophrenia
Oxidative stress

Decreased γ-aminobutyric acid levels in the parietal region of patients with Alzheimer's disease

Bai, X., Edden, R. A. E., Gao, F., Wang, G., Wu, L., Zhao, B., Wang, M., Chan, Q., Chen, W. & Barker, P. B. May 1 2015 In : Journal of Magnetic Resonance Imaging. 41, 5, p. 1326-1331 6 p.

Research output: Contribution to journalArticle

Parietal Lobe
gamma-Aminobutyric Acid
Alzheimer Disease
Spectrum Analysis
Frontal Lobe

Early white matter abnormalities, progressive brain pathology and motor deficits in a novel knock-in mouse model of Huntington's disease

Jin, J., Peng, Q., Hou, Z., Jiang, M., Wang, X., Langseth, A. J., Tao, M., Barker, P. B., Mori, S., Bergles, D. E., Ross, C. A., Detloff, P. J., Zhang, J. & Duan, W. 2015 In : Human Molecular Genetics. 24, 9, p. 2508-2527 20 p.

Research output: Contribution to journalArticle

Huntington Disease
Pathology
Corpus Striatum
Brain
Myelin Sheath
Oxygenation
gamma-Aminobutyric Acid
cortex
Blood
Chemical activation

Multivendor implementation and comparison of volumetric whole-brain echo-planar MR spectroscopic imaging

Sabati, M., Sheriff, S., Gu, M., Wei, J., Zhu, H., Barker, P. B., Spielman, D. M., Alger, J. R. & Maudsley, A. A. Nov 1 2015 In : Magnetic Resonance in Medicine. 74, 5, p. 1209-1220 12 p.

Research output: Contribution to journalArticle

Creatine
Brain
Echo-Planar Imaging
Atlases
Frontal Lobe

Parallel reconstruction in accelerated multivoxel MR spectroscopy

Boer, V. O., Klomp, D. W. J., Laterra, J. & Barker, P. B. Sep 1 2015 In : Magnetic Resonance in Medicine. 74, 3, p. 599-606 8 p.

Research output: Contribution to journalArticle

Magnetic Resonance Spectroscopy
Oligodendroglioma
Motor Cortex
Artifacts
Noise

Reply to: The impact of magnetic resonance spectroscopy in elucidating the role of apolipoprotein E epsilon4 in preclinical Alzheimer's disease

Gomar, J. J., Kingsley, P. B., Uluʇ, A. M., Conejero-Goldberg, C., Barker, P. & Goldberg, T. E. 2015 In : Biological Psychiatry. 77, 8, p. 41-42 2 p.

Research output: Contribution to journalArticle

Apolipoproteins E
Alzheimer Disease
Magnetic Resonance Spectroscopy
Brain
gamma-Aminobutyric Acid
Brain
Occipital Lobe
Healthy Volunteers

Susceptibility-based analysis of dynamic gadolinium bolus perfusion MRI

Bonekamp, D., Barker, P. B., Leigh, R., Van Zijl, P. C. M. & Li, X. Feb 1 2015 In : Magnetic Resonance in Medicine. 73, 2, p. 544-554 11 p.

Research output: Contribution to journalArticle

Gadolinium
Perfusion
Cerebrovascular Circulation
Perfusion Imaging
Hydrodynamics
2014
Ataxia Telangiectasia
Telangiectasis
Nervous System
Hemosiderin
Vascular Malformations

Characterization of peripheral nerve sheath tumors with 3T proton MR spectroscopy

Fayad, L. M., Wang, X., Blakeley, J. O., Durand, D. J., Jacobs, M. A., Demehri, S., Subhawong, T. K., Soldatos, T. & Barker, P. B. 2014 In : American Journal of Neuroradiology. 39, 5, p. 1035-1041 7 p.

Research output: Contribution to journalArticle

Nerve Sheath Neoplasms
Protons
Magnetic Resonance Spectroscopy
Neurilemmoma
trimethylamine

Clinical proton MR spectroscopy in central nervous system disorders

Öz, G. , Alger, J. R. , Barker, P. B. , Bartha, R. , Bizzi, A. , Boesch, C. , Bolan, P. J. , Brindle, K. M. , Cudalbu, C. , Dinçer, A. , Dydak, U. , Emir, U. E. , Frahm, J. , Gilberto González, R. , Gruber, S. , Gruetter, R. , Gupta, R. K. , Heerschap, A. , Henning, A. , Hetherington, H. P. & 3 others Howe, F. A., Hüppi, P. S. & Hurd, R. E. 2014 In : Radiology. 270, 3, p. 658-679 22 p.

Research output: Contribution to journalArticle

Central Nervous System Diseases
Magnetic Resonance Spectroscopy
Metabolic Diseases
Brain Diseases
Demyelinating Diseases
gamma-Aminobutyric Acid
Magnetic Resonance Spectroscopy
Occipital Lobe
Creatine
Healthy Volunteers

Impact of frequency drift on gamma-aminobutyric acid-edited MR spectroscopy

Harris, A. D., Glaubitz, B., Near, J., John Evans, C., Puts, N. A. J., Schmidt-Wilcke, T., Tegenthoff, M., Barker, P. B. & Edden, R. A. E. 2014 In : Magnetic Resonance in Medicine. 72, 4, p. 941-948 8 p.

Research output: Contribution to journalArticle

gamma-Aminobutyric Acid
Magnetic Resonance Spectroscopy
Artifacts
Magnetic Resonance Imaging
Creatine

Multimodal MRI as a diagnostic biomarker for amyotrophic lateral sclerosis

Foerster, B. R., Carlos, R. C., Dwamena, B. A., Callaghan, B. C., Petrou, M., Edden, R. A. E., Mohamed, M. A., Welsh, R. C., Barker, P. B., Feldman, E. L. & Pomper, M. G. 2014 In : Annals of Clinical and Translational Neurology. 1, 2, p. 107-114 8 p.

Research output: Contribution to journalArticle

Diffusion Tensor Imaging
Amyotrophic Lateral Sclerosis
Biomarkers
Magnetic Resonance Imaging
ROC Curve