Research Output 1984 2017

2017

1H-MRS processing parameters affect metabolite quantification: The urgent need for uniform and transparent standardization

Bhogal, A. A., Schür, R. R., Houtepen, L. C., van de Bank, B., Boer, V. O., Marsman, A., Barker, P. B., Scheenen, T. W. J., Wijnen, J. P., Vinkers, C. H. & Klomp, D. W. J. 2017 (Accepted/In press) In : NMR in Biomedicine.

Research output: Research - peer-reviewArticle

Creatine
Metabolites
Standardization
Processing
Phosphocreatine
Image-Guided Biopsy
Amides
Glioma
Protons
Magnetic Resonance Spectroscopy

A simultaneous multi-slice selective J-resolved experiment for fully resolved scalar coupling information

Zeng, Q., Lin, L., Chen, J., Lin, Y., Barker, P. B. & Chen, Z. Sep 1 2017 In : Journal of Magnetic Resonance. 282, p. 27-31 5 p.

Research output: Research - peer-reviewArticle

scalars
protons
Protons
Experiments
molecular structure

Dual-volume excitation and parallel reconstruction for J-difference-edited MR spectroscopy

Oeltzschner, G., Puts, N. A. J., Chan, K. L., Boer, V. O., Barker, P. B. & Edden, R. A. E. Jan 1 2017 In : Magnetic Resonance in Medicine. 77, 1, p. 16-22 7 p.

Research output: Research - peer-reviewArticle

gamma-Aminobutyric Acid
Magnetic Resonance Spectroscopy
Glutathione
Signal-To-Noise Ratio
Healthy Volunteers

Frequency-Dependent Changes in the Amplitude of Low-Frequency Fluctuations in Mild Cognitive Impairment with Mild Depression

Li, Y., Jing, B., Liu, H., Li, Y., Gao, X., Li, Y., Mu, B., Yu, H., Cheng, J., Barker, P. B., Wang, H. & Han, Y. 2017 In : Journal of Alzheimer's Disease. 58, 4, p. 1175-1187 13 p.

Research output: Research - peer-reviewArticle

Depression
Cognitive Dysfunction
Magnetic Resonance Imaging
Parietal Lobe
Brain

Investigation of the contribution of total creatine to the CEST Z-spectrum of brain using a knockout mouse model

Chen, L., Zeng, H., Xu, X., Yadav, N. N., Cai, S., Puts, N. A., Barker, P. B., Li, T., Weiss, R. G., van Zijl, P. C. M. & Xu, J. Dec 1 2017 In : NMR in Biomedicine. 30, 12, e3834

Research output: Research - peer-reviewArticle

Creatine
Knockout Mice
Brain
Phosphocreatine
Guanidine

Normalizing data from GABA-edited MEGA-PRESS implementations at 3 Tesla

Harris, A. D., Puts, N. A. J., Wijtenburg, S. A., Rowland, L. M., Mikkelsen, M., Barker, P. B., Evans, C. J. & Edden, R. A. E. Oct 1 2017 In : Magnetic Resonance Imaging. 42, p. 8-15 8 p.

Research output: Research - peer-reviewArticle

Macromolecules
gamma-Aminobutyric Acid
Datasets
Magnetic resonance imaging
Standardization

Simultaneous detection of glutathione and lactate using spectral editing at 3 T

Chan, K. L., Snoussi, K., Edden, R. A. E. & Barker, P. B. Dec 1 2017 In : NMR in Biomedicine. 30, 12, e3800

Research output: Research - peer-reviewArticle

Glutathione
Lactic Acid
Spectroscopy
Spectrum Analysis
Metabolites

Simultaneous measurement of Aspartate, NAA, and NAAG using HERMES spectral editing at 3 Tesla

Chan, K. L., Saleh, M. G., Oeltzschner, G., Barker, P. B. & Edden, R. A. E. Feb 10 2017 (Accepted/In press) In : NeuroImage.

Research output: Research - peer-reviewArticle

Aspartic Acid
N-acetyl-1-aspartylglutamic acid
N-acetylaspartate
Glutamine
gamma-Aminobutyric Acid

Spatial Hadamard encoding of J-edited spectroscopy using slice-selective editing pulses

Chan, K. L., Oeltzschner, G., Schär, M., Barker, P. B. & Edden, R. A. E. 2017 (Accepted/In press) In : NMR in Biomedicine.

Research output: Research - peer-reviewArticle

gamma-Aminobutyric Acid
Spectroscopy
Spectrum Analysis
Metabolites
Glutathione
2016
Restless Legs Syndrome
Iron
Brain
Substantia Nigra
Sleep

Correlates of virtual navigation performance in older adults

Korthauer, L. E., Nowak, N. T., Moffat, S. D., An, Y., Rowland, L. M., Barker, P. B., Resnick, S. M. & Driscoll, I. Mar 1 2016 In : Neurobiology of Aging. 39, p. 118-127 10 p.

Research output: Research - peer-reviewArticle

Water
Learning
Anisotropy
Task Performance and Analysis
Prefrontal Cortex

Decoupling of Brain Temperature and Glutamate in Recent Onset of Schizophrenia: A 7T Proton Magnetic Resonance Spectroscopy Study

Posporelis, S., Coughlin, J. M., Marsman, A., Pradhan, S., Tanaka, T., Wang, H., Varvaris, M., Ward, R., Higgs, C., Edwards, J. A., Ford, C. N., Kim, P. K., Lloyd, A. M., Edden, R. A. E., Schretlen, D. J., Cascella, N. G., Barker, P. B. & Sawa, A. Dec 27 2016 (Accepted/In press) In : Biological Psychiatry: Cognitive Neuroscience and Neuroimaging.

Research output: Research - peer-reviewArticle

Glutamic Acid
Schizophrenia
Temperature
Brain
Proton Magnetic Resonance Spectroscopy

Echo time optimization for J-difference editing of glutathione at 3T

Chan, K. L., Puts, N. A. J., Snoussi, K., Harris, A. D., Barker, P. B. & Edden, R. A. E. 2016 (Accepted/In press) In : Magnetic Resonance in Medicine.

Research output: Research - peer-reviewArticle

Glutathione
Healthy Volunteers

GABA quantitation using MEGA-PRESS: Regional and hemispheric differences

Grewal, M., Dabas, A., Saharan, S., Barker, P. B., Edden, R. A. E. & Mandal, P. K. 2016 (Accepted/In press) In : Journal of Magnetic Resonance Imaging.

Research output: Research - peer-reviewArticle

gamma-Aminobutyric Acid
Occipital Lobe
Parietal Lobe
Frontal Lobe
Linear Models

HERMES: Hadamard encoding and reconstruction of MEGA-edited spectroscopy

Chan, K. L., Puts, N. A. J., Schär, M., Barker, P. B. & Edden, R. A. E. Jul 1 2016 In : Magnetic Resonance in Medicine. 76, 1, p. 11-19 9 p.

Research output: Research - peer-reviewArticle

Spectrum Analysis
N-acetyl-1-aspartylglutamic acid
N-acetylaspartate
Aspartic Acid
Glutathione

Prospective frequency correction for macromolecule-suppressed GABA editing at 3T

Edden, R. A. E., Oeltzschner, G., Harris, A. D., Puts, N. A. J., Chan, K. L., Boer, V. O., Schär, M. & Barker, P. B. 2016 (Accepted/In press) In : Journal of Magnetic Resonance Imaging.

Research output: Research - peer-reviewArticle

gamma-Aminobutyric Acid
Water

Quantifying spectra in the frequency domain

Pradhan, S., Soher, B. J. & Barker, P. B. 2016 In : eMagRes. 5, 2, p. 1247-1256 10 p.

Research output: Research - peer-reviewArticle

Magnetic resonance
Magnetic Resonance Spectroscopy
Data acquisition
Curve fitting
Metabolites

The MRI Helium Crisis: Past and Future

Mahesh, M. & Barker, P. B. Dec 1 2016 In : Journal of the American College of Radiology. 13, 12, p. 1536-1537 2 p.

Research output: Research - peer-reviewArticle

2015
Globus Pallidus
Neuroimaging
gamma-Aminobutyric Acid
Energy Metabolism
succinic semialdehyde dehydrogenase deficiency

Age-related changes in anterior cingulate cortex glutamate in schizophrenia: A 1H MRS Study at 7Tesla

Brandt, A. S., Unschuld, P. G., Pradhan, S., Lim, I. A. L., Churchill, G., Harris, A. D., Hua, J., Barker, P. B., Ross, C. A., van Zijl, P. C. M., Edden, R. A. E. & Margolis, R. L. Dec 25 2015 (Accepted/In press) In : Schizophrenia Research.

Research output: Research - peer-reviewArticle

Gyrus Cinguli
Glutamic Acid
Schizophrenia
Magnetic Resonance Spectroscopy
Glutamine

Comparison of brain gray and white matter macromolecule resonances at 3 and 7 Tesla

Snoussi, K., Gillen, J. S., Horska, A., Puts, N. A. J., Pradhan, S., Edden, R. A. E. & Barker, P. B. Sep 1 2015 In : Magnetic Resonance in Medicine. 74, 3, p. 607-613 7 p.

Research output: Research - peer-reviewArticle

Gyrus Cinguli
Protons
Brain
Gray Matter
White Matter

Comparison of single voxel brain MRS AT 3T and 7T using 32-channel head coils

Pradhan, S., Bonekamp, S., Gillen, J. S., Rowland, L. M., Wijtenburg, S. A., Edden, R. A. E. & Barker, P. B. Oct 1 2015 In : Magnetic Resonance Imaging. 33, 8, p. 1013-1018 6 p.

Research output: Research - peer-reviewArticle

Magnetic resonance spectroscopy
Metabolites
Brain
Signal-To-Noise Ratio
Magnetic Resonance Spectroscopy

Co-registration of magnetic resonance spectroscopy and transcranial magnetic stimulation

Hone-Blanchet, A., Salas, R. E., Celnik, P., Kalloo, A., Schar, M., Puts, N. A. J., Harris, A. D., Barker, P. B., Fecteau, S., Earley, C. J., Allen, R. P. & Edden, R. A. Mar 5 2015 In : Journal of Neuroscience Methods. 242, p. 52-57 6 p.

Research output: Research - peer-reviewArticle

Transcranial Magnetic Stimulation
Magnetic Resonance Spectroscopy
Neurotransmitter Agents
Motor Cortex
Hand

Cortical brain atrophy and intra-individual variability in neuropsychological test performance in HIV disease

Hines, L. J., Miller, E. N., Hinkin, C. H., Alger, J. R., Barker, P., Goodkin, K., Martin, E. M., Maruca, V., Ragin, A., Sacktor, N., Sanders, J., Selnes, O., Becker, J. T. & For The Multicenter Aids Cohort Study, T. M. A. C. S. Aug 25 2015 (Accepted/In press) In : Brain Imaging and Behavior.

Research output: Research - peer-reviewArticle

Neuropsychological Tests
Atrophy
HIV
Brain
Parietal Lobe

Decoupling of N-acetyl-aspartate and glutamate within the dorsolateral prefrontal cortex in schizophrenia

Coughlin, J. M., Tanaka, T., Marsman, A., Wang, H., Bonekamp, S., Kim, P. K., Higgs, C., Varvaris, M., Edden, R., Pomper, M., Schretlen, D., Barker, P. B. & Sawa, A. 2015 In : Current Molecular Medicine. 15, 2, p. 176-183 8 p.

Research output: Research - peer-reviewArticle

Prefrontal Cortex
Glutamic Acid
Schizophrenia
N-acetylaspartate
Creatine

Decreased γ-aminobutyric acid levels in the parietal region of patients with Alzheimer's disease

Bai, X., Edden, R. A. E., Gao, F., Wang, G., Wu, L., Zhao, B., Wang, M., Chan, Q., Chen, W. & Barker, P. B. May 1 2015 In : Journal of Magnetic Resonance Imaging. 41, 5, p. 1326-1331 6 p.

Research output: Research - peer-reviewArticle

Parietal Lobe
gamma-Aminobutyric Acid
Alzheimer Disease
Spectrum Analysis
Frontal Lobe

Early white matter abnormalities, progressive brain pathology and motor deficits in a novel knock-in mouse model of Huntington's disease

Jin, J., Peng, Q., Hou, Z., Jiang, M., Wang, X., Langseth, A. J., Tao, M., Barker, P. B., Mori, S., Bergles, D. E., Ross, C. A., Detloff, P. J., Zhang, J. & Duan, W. 2015 In : Human Molecular Genetics. 24, 9, p. 2508-2527 20 p.

Research output: Research - peer-reviewArticle

Huntington Disease
Pathology
Brain
White Matter
Corpus Striatum

Multi-regional investigation of the relationship between functional MRI blood oxygenation level dependent (BOLD) activation and GABA concentration

Harris, A. D., Puts, N. A. J., Anderson, B. A., Yantis, S., Pekar, J. J., Barker, P. B. & Edden, R. A. E. Feb 20 2015 In : PLoS One. 10, 2, e0117531

Research output: Research - peer-reviewArticle

Oxygenation
gamma-Aminobutyric Acid
Blood
Chemical activation
Magnetic Resonance Imaging

Multivendor implementation and comparison of volumetric whole-brain echo-planar MR spectroscopic imaging

Sabati, M., Sheriff, S., Gu, M., Wei, J., Zhu, H., Barker, P. B., Spielman, D. M., Alger, J. R. & Maudsley, A. A. Nov 1 2015 In : Magnetic Resonance in Medicine. 74, 5, p. 1209-1220 12 p.

Research output: Research - peer-reviewArticle

Brain
N-acetylaspartate
Creatine
Echo-Planar Imaging
Atlases

Parallel reconstruction in accelerated multivoxel MR spectroscopy

Boer, V. O., Klomp, D. W. J., Laterra, J. & Barker, P. B. Sep 1 2015 In : Magnetic Resonance in Medicine. 74, 3, p. 599-606 8 p.

Research output: Research - peer-reviewArticle

Magnetic Resonance Spectroscopy
Oligodendroglioma
Motor Cortex
Artifacts
Noise

Reply to: The impact of magnetic resonance spectroscopy in elucidating the role of apolipoprotein E epsilon4 in preclinical Alzheimer's disease

Gomar, J. J., Kingsley, P. B., Uluʇ, A. M., Conejero-Goldberg, C., Barker, P. & Goldberg, T. E. 2015 In : Biological Psychiatry. 77, 8, p. 41-42 2 p.

Research output: Research - peer-reviewArticle

Spectral-editing measurements of GABA in the human brain with and without macromolecule suppression

Harris, A. D., Puts, N. A. J., Barker, P. B. & Edden, R. A. E. Dec 1 2015 In : Magnetic Resonance in Medicine. 74, 6, p. 1523-1529 7 p.

Research output: Research - peer-reviewArticle

gamma-Aminobutyric Acid
Brain
Occipital Lobe
Healthy Volunteers
Sensorimotor Cortex

Susceptibility-based analysis of dynamic gadolinium bolus perfusion MRI

Bonekamp, D., Barker, P. B., Leigh, R., Van Zijl, P. C. M. & Li, X. Feb 1 2015 In : Magnetic Resonance in Medicine. 73, 2, p. 544-554 11 p.

Research output: Research - peer-reviewArticle

Gadolinium
Perfusion
Cerebrovascular Circulation
Perfusion Imaging
Hydrodynamics
2014
Ataxia Telangiectasia
Telangiectasis
Nervous System
Brain
Hemosiderin

Characterization of peripheral nerve sheath tumors with 3T proton MR spectroscopy

Fayad, L. M., Wang, X., Blakeley, J. O., Durand, D. J., Jacobs, M. A., Demehri, S., Subhawong, T. K., Soldatos, T. & Barker, P. B. 2014 In : American Journal of Neuroradiology. 39, 5, p. 1035-1041 7 p.

Research output: Research - peer-reviewArticle

Nerve Sheath Neoplasms
Protons
Magnetic Resonance Spectroscopy
trimethylamine
Neurilemmoma

Clinical proton MR spectroscopy in central nervous system disorders

Öz, G. , Alger, J. R. , Barker, P. B. , Bartha, R. , Bizzi, A. , Boesch, C. , Bolan, P. J. , Brindle, K. M. , Cudalbu, C. , Dinçer, A. , Dydak, U. , Emir, U. E. , Frahm, J. , Gilberto González, R. , Gruber, S. , Gruetter, R. , Gupta, R. K. , Heerschap, A. , Henning, A. , Hetherington, H. P. & 3 others Howe, F. A., Hüppi, P. S. & Hurd, R. E. 2014 In : Radiology. 270, 3, p. 658-679 22 p.

Research output: Research - peer-reviewArticle

Central Nervous System Diseases
Magnetic Resonance Spectroscopy
Proton Magnetic Resonance Spectroscopy
Metabolic Diseases
Brain Diseases

Gannet: A batch-processing tool for the quantitative analysis of gamma-aminobutyric acid-edited MR spectroscopy spectra

Edden, R. A. E., Puts, N. A. J., Harris, A. D., Barker, P. B. & Evans, C. J. Dec 1 2014 In : Journal of Magnetic Resonance Imaging. 40, 6, p. 1445-1452 8 p.

Research output: Research - peer-reviewArticle

gamma-Aminobutyric Acid
Magnetic Resonance Spectroscopy
Occipital Lobe
Creatine
Healthy Volunteers

Impact of frequency drift on gamma-aminobutyric acid-edited MR spectroscopy

Harris, A. D., Glaubitz, B., Near, J., John Evans, C., Puts, N. A. J., Schmidt-Wilcke, T., Tegenthoff, M., Barker, P. B. & Edden, R. A. E. 2014 In : Magnetic Resonance in Medicine. 72, 4, p. 941-948 8 p.

Research output: Research - peer-reviewArticle

gamma-Aminobutyric Acid
Magnetic Resonance Spectroscopy
Artifacts
Magnetic Resonance Imaging
Creatine

Multimodal MRI as a diagnostic biomarker for amyotrophic lateral sclerosis

Foerster, B. R., Carlos, R. C., Dwamena, B. A., Callaghan, B. C., Petrou, M., Edden, R. A. E., Mohamed, M. A., Welsh, R. C., Barker, P. B., Feldman, E. L. & Pomper, M. G. 2014 In : Annals of Clinical and Translational Neurology. 1, 2, p. 107-114 8 p.

Research output: Research - peer-reviewArticle

Diffusion Tensor Imaging
Amyotrophic Lateral Sclerosis
Biomarkers
Magnetic Resonance Imaging
ROC Curve
Intracranial Hemorrhages
Tissue Plasminogen Activator
Blood-Brain Barrier
Stroke
Therapeutics

Proton magnetic resonance spectroscopy of skeletal muscle: A comparison of two quantitation techniques

Wang, X., Salibi, N., Fayad, L. M. & Barker, P. B. 2014 In : Journal of Magnetic Resonance. 243, p. 81-84 4 p.

Research output: Research - peer-reviewArticle

skeletal muscle
proton magnetic resonance
magnetic resonance spectroscopy
water
Magnetic resonance spectroscopy
Alzheimer Disease
Magnetic Resonance Spectroscopy
Cognitive Dysfunction
Dementia
Brain
2013

1H magnetic resonance spectroscopy findings in idiopathic inflammatory myopathies at 3 T: Feasibility and first results

Subhawong, T. K., Wang, X., MacHado, A. J., Mammen, A. L., Christopher-Stine, L., Barker, P. B., Carrino, J. A. & Fayad, L. M. Jul 2013 In : Investigative Radiology. 48, 7, p. 509-516 8 p.

Research output: Research - peer-reviewArticle

Myositis
Magnetic Resonance Spectroscopy
Magnetic Resonance Imaging
Creatine
Healthy Volunteers

Acceleration of 1H MR metabolic imaging with compressed sensing

Barker, P. B. & Ernst, T. M. Feb 2013 In : Radiology. 266, 2, p. 686-687 2 p.

Research output: Research - peer-reviewArticle

Amyotrophic Lateral Sclerosis
Neurotransmitter Agents
Proton Magnetic Resonance Spectroscopy
Riluzole
Motor Cortex

Determining the in vivo transverse relaxation time of GABA in the human brain at 7T

Intrapiromkul, J., Zhu, H., Cheng, Y., Barker, P. B. & Edden, R. A. E. Nov 2013 In : Journal of Magnetic Resonance Imaging. 38, 5, p. 1224-1229 6 p.

Research output: Research - peer-reviewArticle

gamma-Aminobutyric Acid
Brain
Healthy Volunteers

Diagnosis and characterization of brain tumors: MR spectroscopic imaging

Barker, P. B. May 1 2013 Functional Brain Tumor Imaging. Springer New York, p. 39-55 17 p.

Research output: ResearchChapter

Tumors
Brain
Imaging techniques
Brain Neoplasms
Magnetic resonance spectroscopy

Edited magnetic resonance spectroscopy detects an age-related decline in brain GABA levels

Gao, F., Edden, R. A. E., Li, M., Puts, N. A. J., Wang, G., Liu, C., Zhao, B., Wang, H., Bai, X., Zhao, C., Wang, X. & Barker, P. B. Sep 2013 In : NeuroImage. 78, p. 75-82 8 p.

Research output: Research - peer-reviewArticle

gamma-Aminobutyric Acid
Magnetic Resonance Spectroscopy
Brain
Parietal Lobe
Neurotransmitter Agents

GABA predicts inhibition of frequency-specific oscillations in schizophrenia

Rowland, L. M., Edden, R. A. E., Kontson, K., Zhu, H., Barker, P. B. & Elliot Hong, L. 2013 In : Journal of Neuropsychiatry and Clinical Neurosciences. 25, 1, p. 83-87 5 p.

Research output: Research - peer-reviewArticle

Butyric Acid
Schizophrenia
Inhibition (Psychology)
Brain