Peter Abadir

Associate Professor

20032019
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Research Output 2003 2019

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Article

Age- and Genotype-Specific Effects of the Angiotensin-Converting Enzyme Inhibitor Lisinopril on Mitochondrial and Metabolic Parameters in Drosophila melanogaster

Ederer, K. A., Jin, K., Bouslog, S., Wang, L., Gorman, G. S., Rowe, G. C., Abadir, P., Raftery, D., Moellering, D., Promislow, D., Jumbo-Lucioni, P. & De Luca, M., Oct 26 2018, In : International Journal of Molecular Sciences. 19, 11

Research output: Contribution to journalArticle

enzyme inhibitors
angiotensins
Lisinopril
Drosophila
Drosophila melanogaster

Angiotensin AT2 receptors directly stimulate renal nitric oxide in Bradykinin B2-receptor-null mice

Abadir, P., Carey, R. M. & Siragy, H. M., Oct 1 2003, In : Hypertension. 42, 4 I, p. 600-604 5 p.

Research output: Contribution to journalArticle

Angiotensin Type 2 Receptor
Bradykinin B2 Receptors
Angiotensins
Nitric Oxide
Kidney

Angiotensin II type 2 receptor-bradykinin B2 receptor functional heterodimerization

Abadir, P., Periasamy, A., Carey, R. M. & Siragy, H. M., Aug 2006, In : Hypertension. 48, 2, p. 316-322 7 p.

Research output: Contribution to journalArticle

Activating Transcription Factor 2
Angiotensin Type 2 Receptor
Bradykinin B2 Receptors
Fluorescence Resonance Energy Transfer
Protein Tyrosine Phosphatases
STAT Transcription Factors
Angiotensin Type 2 Receptor
STAT3 Transcription Factor
Angiotensins
Phosphorylation

Angiotensin subtype-2 receptors inhibit renin biosynthesis and angiotensin II formation

Siragy, H. M., Xue, C., Abadir, P. & Carey, R. M., Jan 2005, In : Hypertension. 45, 1, p. 133-137 5 p.

Research output: Contribution to journalArticle

Angiotensins
Renin
Angiotensin II
Valsartan
Sodium
Angiotensin Type 1 Receptor
Dinoprostone
Dinoprost
Kidney
Angiotensins

Chronic wound repair and healing in older adults: Current status and future research

Gould, L., Abadir, P., Brem, H., Carter, M., Conner-Kerr, T., Davidson, J., Dipietro, L., Falanga, V., Fife, C., Gardner, S., Grice, E., Harmon, J., Hazzard, W. R., High, K. P., Houghton, P., Jacobson, N., Kirsner, R. S., Kovacs, E. J., Margolis, D., McFarland Horne, F. & 9 others, Reed, M. J., Sullivan, D. H., Thom, S., Tomic-Canic, M., Walston, J. D., Whitney, J., Williams, J., Zieman, S. & Schmader, K., Jan 1 2015, In : Wound Repair and Regeneration. 23, 1, p. 1-13 13 p.

Research output: Contribution to journalArticle

Wound Healing
Wounds and Injuries
National Institute on Aging (U.S.)
Research
Randomized Controlled Trials

Chronic wound repair and healing in older adults: Current status and future research

Gould, L., Abadir, P., Brem, H., Carter, M., Conner-Kerr, T., Davidson, J., Dipietro, L., Falanga, V., Fife, C., Gardner, S., Grice, E., Harmon, J., Hazzard, W. R., High, K. P., Houghton, P., Jacobson, N., Kirsner, R. S., Kovacs, E. J., Margolis, D., McFarland Horne, F. & 9 others, Reed, M. J., Sullivan, D. H., Thom, S., Tomic-Canic, M., Walston, J. D., Whitney, J. A., Williams, J., Zieman, S. & Schmader, K., Mar 1 2015, In : Journal of the American Geriatrics Society. 63, 3, p. 427-438 12 p.

Research output: Contribution to journalArticle

Wound Healing
Wounds and Injuries
National Institute on Aging (U.S.)
Research
Comorbidity

Co-Localization of Macrophage Inhibitory Factor and Nix in Skeletal Muscle of the Aged Male Interleukin 10 Null Mouse

Abadir, P., Ko, F., Marx, R., Powell, L., Kieserman, E., Yang, H. & Walston, J., Jan 1 2017, In : The Journal of frailty & aging. 6, 3, p. 118-121 4 p.

Research output: Contribution to journalArticle

Interleukin-10
Skeletal Muscle
Macrophages
Inflammation
Proteins

Combined effects of aging and inflammation on renin-angiotensin system mediate mitochondrial dysfunction and phenotypic changes in cardiomyopathies

Burks, T. N., Marx-Rattner, R., Powell, L., Rucker, J., Bedja, D., Heacock, E., Smith, B. J., Foster, D. B., Kass, D. A., O'Rourke, B., Walston, J. D. & Abadir, P., 2015, In : Oncotarget. 6, 14, p. 11979-11993 15 p.

Research output: Contribution to journalArticle

Renin-Angiotensin System
Cardiomyopathies
Inflammation
Myocardium
Premature Aging

Discovery and Validation of Agonistic Angiotensin Receptor Autoantibodies as Biomarkers of Adverse Outcomes

Abadir, P., Jain, A., Powell, L. J., Xue, Q. L., Tian, J., Hamilton, R. G., Bennett, D. A., Finucane, T., Walston, J. D. & Fedarko, N. S., Jan 31 2017, In : Circulation. 135, 5, p. 449-459 11 p.

Research output: Contribution to journalArticle

Angiotensin Type 1 Receptor
Angiotensin Receptors
Autoantibodies
Biomarkers
Angiotensin Receptor Antagonists

Dual peptide conjugation strategy for improved cellular uptake and mitochondria targeting

Lin, R., Zhang, P., Cheetham, A. G., Walston, J. D., Abadir, P. & Cui, H., Jan 21 2015, In : Bioconjugate Chemistry. 26, 1, p. 71-77 7 p.

Research output: Contribution to journalArticle

Mitochondria
Peptides
Cell-Penetrating Peptides
Molecules
Cell membranes

Failure of Glucose Monitoring in an Individual with Pseudohypoglycemia

Lee, K. T. & Abadir, P., Aug 1 2015, In : Journal of the American Geriatrics Society. 63, 8, p. 1706-1708 3 p.

Research output: Contribution to journalArticle

Blood Glucose Self-Monitoring
Raynaud Disease
Regional Blood Flow
Microcirculation
Diagnostic Errors

Identification and characterization of a functional mitochondrial angiotensin system

Abadir, P., Foster, D. B., Crow, M., Cooke, C. A., Rucker, J. J., Jain, A., Smith, B. J., Burks, T. N., Cohn, R. D., Fedarko, N. S., Carey, R. M., O'Rourke, B. & Walston, J. D., Sep 6 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 36, p. 14849-14854 6 p.

Research output: Contribution to journalArticle

Angiotensins
Angiotensin Receptors
Angiotensin Type 1 Receptor
Renin-Angiotensin System
Mitochondria
Mitochondrial Degradation
Autophagy
Interleukin-10
Muscle
Skeletal Muscle

Intrinsic aerobic capacity sets a divide for aging and longevity

Koch, L. G., Kemi, O. J., Qi, N., Leng, S., Bijma, P., Gilligan, L. J., Wilkinson, J. E., Wisløff, H., Høydal, M. A., Rolim, N., Abadir, P., Van Grevenhof, E. M., Smith, G. L., Burant, C. F., Ellingsen, Ø., Britton, S. L. & Wisløff, U., Oct 28 2011, In : Circulation Research. 109, 10, p. 1162-1172 11 p.

Research output: Contribution to journalArticle

Exercise
Premature Mortality
Running
Walking
Cardiovascular Diseases

Knockout of Angiotensin AT2 receptors accelerates healing but impairs quality

Faghih, M., Hosseini, S. M., Smith, B., Ansari, A. M., Lay, F., Ahmed, A. K., Inagami, T., Marti, G. P., Harmon, J., Walston, J. D. & Abadir, P., 2015, In : Aging. 7, 12, p. 1185-1197 13 p.

Research output: Contribution to journalArticle

Angiotensin Type 2 Receptor
Angiotensin Type 1 Receptor
Wound Healing
Wounds and Injuries
Skin

Lisinopril Preserves Physical Resilience and Extends Life Span in a Genotype-Specific Manner in Drosophila melanogaster

Gabrawy, M. M., Campbell, S., Carbone, M. A., Morozova, T. V., Arya, G. H., Turlapati, L. B., Walston, J. D., Starz-Gaiano, M., Everett, L., Mackay, T. F. C., Leips, J. & Abadir, P. M., Nov 13 2019, In : The journals of gerontology. Series A, Biological sciences and medical sciences. 74, 12, p. 1844-1852 9 p.

Research output: Contribution to journalArticle

Open Access
Lisinopril
Drosophila melanogaster
Genotype
Angiotensin-Converting Enzyme Inhibitors
Skeletal Muscle

Losartan improves measures of activity, inflammation, and oxidative stress in older mice

Lin, C. H., Yang, H., Xue, Q. L., Chuang, Y. F., Roy, C. N., Abadir, P. & Walston, J. D., 2014, In : Experimental Gerontology. 58, p. 174-178 5 p.

Research output: Contribution to journalArticle

Oxidative stress
Losartan
Oxidative Stress
Inflammation
Angiotensins

Rapamycin increases grip strength and attenuates age-related decline in maximal running distance in old low capacity runner rats

Xue, Q. L., Yang, H., Li, H., Abadir, P., Burks, T. N., Koch, L. G., Britton, S. L., Carlson, J., Chen, L., Walston, J. D. & Leng, S., Apr 1 2016, In : Aging. 8, 4, p. 769-776 8 p.

Research output: Contribution to journalArticle

Hand Strength
Sirolimus
Running
Placebos
Diet
12-Hydroxy-5,8,10,14-eicosatetraenoic Acid
Angiotensin Type 2 Receptor
Angiotensin Type 1 Receptor
Valsartan
Kidney

Subcellular characteristics of functional intracellular renin-angiotensin systems

Abadir, P., Walston, J. D. & Carey, R. M., Dec 2012, In : Peptides. 38, 2, p. 437-445 9 p.

Research output: Contribution to journalArticle

Angiotensins
Renin-Angiotensin System
Renin
Angiotensin I
Angiotensinogen

The angiotensin II type 1 receptor mediates renal interstitial content of tumor necrosis factor-α in diabetic rats

Siragy, H. M., Awad, A., Abadir, P. & Webb, R., Jun 1 2003, In : Endocrinology. 144, 6, p. 2229-2233 5 p.

Research output: Contribution to journalArticle

Valsartan
Angiotensin Type 1 Receptor
Angiotensin II
Tumor Necrosis Factor-alpha
Extracellular Fluid

The Frail Renin-Angiotensin System

Abadir, P., Feb 2011, In : Clinics in Geriatric Medicine. 27, 1, p. 53-65 13 p.

Research output: Contribution to journalArticle

Renin-Angiotensin System
Angiotensin II
Blood Vessels
Angiotensin Type 2 Receptor
Angiotensin Type 1 Receptor
Angiotensins
Renin-Angiotensin System
Angiotensin II
Free Radicals
Reactive Oxygen Species

The unknown profession: A geriatrician

Campbell, J. Y., Durso, S., Brandt, L. E., Finucane, T. & Abadir, P., Mar 2013, In : Journal of the American Geriatrics Society. 61, 3, p. 447-449 3 p.

Research output: Contribution to journalArticle

Geriatrics
Ice Cream
Baltimore
Quality of Health Care
Public Health

Topical Reformulation of Valsartan for Treatment of Chronic Diabetic Wounds

Abadir, P., Hosseini, S., Faghih, M., Ansari, A., Lay, F., Smith, B., Beselman, A., Vuong, D., Berger, A., Tian, J., Rini, D. A., Keenahan, K., Budman, J., Inagami, T., Fedarko, N. S., Marti, G., Harmon, J. & Walston, J. D., Feb 1 2018, In : Journal of Investigative Dermatology. 138, 2, p. 434-443 10 p.

Research output: Contribution to journalArticle

Valsartan
Angiotensins
Smad Proteins
Wound Healing
Angiotensin II Type 1 Receptor Blockers
Advance Directive Adherence
Life Support Care
Dissent and Disputes
Nuclear Family

When Women Rise, We All Rise: American Geriatrics Society Position Statement on Achieving Gender Equity in Geriatrics

Boxer, R., Norman, M., Abadir, P., Beizer, J. L., Dierich, M., Lau, S., Linnebur, S. A., Lundebjerg, N. E., Naik, A. D., Schreiber, R., Unroe, K., Mikhailovich, A. L. & Goldstein, A. C., Jan 1 2019, (Accepted/In press) In : Journal of the American Geriatrics Society.

Research output: Contribution to journalArticle

Open Access
Geriatrics
Working Women
Women's Rights
Public Health
Delivery of Health Care