Research output per year
Research output per year
- 1 - 50 out of 63 results
Search results
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2024
Artificial intelligence and technology collaboratories: Empowering innovation in AI + AgeTech
Li, R. M., Abadir, P. M., Battle, A., Chellappa, R., Choudhry, N. K., Demiris, G., Ganesan, D., Karlawish, J., Moore, J. H. & Walston, J. D., 2024, (Accepted/In press) In: Journal of the American Geriatrics Society.Research output: Contribution to journal › Letter › peer-review
Open Access -
Artificial Intelligence and Technology Collaboratories: Innovating aging research and Alzheimer's care
Abadir, P., Oh, E., Chellappa, R., Choudhry, N., Demiris, G., Ganesan, D., Karlawish, J., Marlin, B., Li, R. M., Dehak, N., Arbaje, A., Unberath, M., Cudjoe, T., Chute, C., Moore, J. H., Phan, P., Samus, Q., Schoenborn, N. L., Battle, A. & Walston, J. D., 2024, (Accepted/In press) In: Alzheimer's and Dementia.Research output: Contribution to journal › Article › peer-review
Open Access -
Artificial Intelligence in Geriatrics: Riding the Inevitable Tide of Promise, Challenges, and Considerations
Abadir, P. & Chellappa, R., Feb 1 2024, In: The journals of gerontology. Series A, Biological sciences and medical sciences. 79, 2Research output: Contribution to journal › Article › peer-review
Open Access -
Dual treatment with kynurenine pathway inhibitors and NAD+ precursors synergistically extends life span in Drosophila
Gabrawy, M. M., Westbrook, R., King, A., Khosravian, N., Ochaney, N., DeCarvalho, T., Wang, Q., Yu, Y., Huang, Q., Said, A., Abadir, M., Zhang, C., Khare, P., Fairman, J. E., Le, A., Milne, G. L., Vonhoff, F. J., Walston, J. D. & Abadir, P. M., 2024, (Accepted/In press) In: Aging Cell.Research output: Contribution to journal › Article › peer-review
Open Access -
Geriatric research through the lens of AGS/NIA U13: Two decades of interdisciplinary dialogues that have propelled the field
Abadir, P. & Whitson, H., 2024, (Accepted/In press) In: Journal of the American Geriatrics Society.Research output: Contribution to journal › Letter › peer-review
Open Access -
Unlocking the protective potential of the angiotensin type 2 receptor (AT2R) in acute lung injury and age-related pulmonary dysfunction
Abadir, P., Cosarderelioglu, C., Damarla, M., Malinina, A., Dikeman, D., Marx-Rattner, R., Nader, M. M., Abadir, M., Walston, J. & Neptune, E., Feb 2024, In: Biochemical Pharmacology. 220, 115978.Research output: Contribution to journal › Article › peer-review
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2023
Angiotensin receptor blocker use is associated with upregulation of the memory-protective angiotensin type 4 receptor (AT4R) in the postmortem brains of individuals without cognitive impairment
Cosarderelioglu, C., Nidadavolu, L. S., George, C. J., Marx-Rattner, R., Powell, L., Xue, Q. L., Tian, J., Oh, E. S., Ferrucci, L., Dincer, P., Bennett, D. A., Walston, J. D. & Abadir, P. M., Feb 2023, In: GeroScience. 45, 1, p. 371-384 14 p.Research output: Contribution to journal › Article › peer-review
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An overview of the resilience world: Proceedings of the American Geriatrics Society and National Institute on Aging State of Resilience Science Conference
Abadir, P. M., Bandeen-Roche, K., Bergeman, C., Bennett, D., Davis, D., Kind, A., LeBrasseur, N., Stern, Y., Varadhan, R. & Whitson, H. E., 2023, (Accepted/In press) In: Journal of the American Geriatrics Society.Research output: Contribution to journal › Article › peer-review
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Associations between circulating cell-free mitochondrial DNA, inflammatory markers, and cognitive and physical outcomes in community dwelling older adults
Nidadavolu, L. S., Feger, D., Chen, D., Wu, Y., Grodstein, F., Gross, A. L., Bennett, D. A., Walston, J. D., Oh, E. S. & Abadir, P. M., Dec 2023, In: Immunity and Ageing. 20, 1, 24.Research output: Contribution to journal › Article › peer-review
Open Access -
A Study of Physical Resilience and Aging (SPRING): Conceptual framework, rationale, and study design
Walston, J., Varadhan, R., Xue, Q. L., Buta, B., Sieber, F., Oni, J., Imus, P., Crews, D. C., Artz, A., Schrack, J., Kalyani, R. R., Abadir, P., Carlson, M., Hladek, M., McAdams-DeMarco, M., Jones, R., Johnson, A., Shafi, T., Newman, A. B. & Bandeen-Roche, K., Aug 2023, In: Journal of the American Geriatrics Society. 71, 8, p. 2393-2405 13 p.Research output: Contribution to journal › Article › peer-review
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Centrally Acting ACE Inhibitor Use and Physical Performance in Older Adults
George, C. J., Hall, C. B., Weiss, E. F., Verghese, J., Neptune, E. & Abadir, P., Feb 2023, In: The Journal of frailty & aging. 12, 2, p. 103-108 6 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Decoding Angiotensin Receptors: TOMAHAQ-Based Detection and Quantification of Angiotensin Type-1 and Type-2 Receptors
Cosarderelioglu, C., Kreimer, S., Plaza-Rodriguez, A. I., Iglesias, P. A., Talbot, C. C., Siragy, H. M., Carey, R. M., Ubaida-Mohien, C., O’rourke, B., Ferrucci, L., Bennett, D. A., Walston, J. & Abadir, P., Sep 19 2023, In: Journal of the American Heart Association. 12, 18, e030791.Research output: Contribution to journal › Article › peer-review
Open Access -
Evaluating genomic signatures of aging in brain tissue as it relates to Alzheimer’s disease
Lynch, M. T., Taub, M. A., Farfel, J. M., Yang, J., Abadir, P., De Jager, P. L., Grodstein, F., Bennett, D. A. & Mathias, R. A., Dec 2023, In: Scientific reports. 13, 1, 14747.Research output: Contribution to journal › Article › peer-review
Open Access -
Interleukin-6 Drives Mitochondrial Dysregulation and Accelerates Physical Decline: Insights From an Inducible Humanized IL-6 Knock-In Mouse Model
Nidadavolu, L. S., Cosarderelioglu, C., Merino Gomez, A., Wu, Y., Bopp, T., Zhang, C., Nguyen, T., Marx-Rattner, R., Yang, H., Antonescu, C., Florea, L., Talbot, C. C., Smith, B., Foster, D. B., Fairman, J. E., Yenokyan, G., Chung, T., Le, A., Walston, J. D. & Abadir, P. M., Oct 9 2023, In: The journals of gerontology. Series A, Biological sciences and medical sciences. 78, 10, p. 1740-1752 13 p.Research output: Contribution to journal › Article › peer-review
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Navigating and diagnosing cognitive frailty in research and clinical domains
Nader, M. M., Cosarderelioglu, C., Miao, E., Whitson, H., Xue, Q. L., Grodstein, F., Oh, E., Ferrucci, L., Bennett, D. A., Walston, J. D., George, C. & Abadir, P. M., Nov 2023, In: Nature Aging. 3, 11, p. 1325-1333 9 p.Research output: Contribution to journal › Article › peer-review
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The promise of AI and technology to improve quality of life and care for older adults
Directors & Advisors of the AITCs, Jun 2023, In: Nature Aging. 3, 6, p. 629-631 3 p.Research output: Contribution to journal › Letter › peer-review
Open Access -
2022
AGS and NIA bench-to bedside conference summary: Cancer and cardiovascular disease
Mohile, S., Blaum, C. S., Abadir, P. M., Dale, W., Forman, D. E., Fung, C., Holmes, H. M., Moslehi, J., Mustian, K. M., Rich, M. W. & Whitson, H. E., Oct 2022, In: Journal of the American Geriatrics Society. 70, 10, p. 2764-2774 11 p.Research output: Contribution to journal › Article › peer-review
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Circulating Cell-Free Genomic DNA Is Associated with an Increased Risk of Dementia and with Change in Cognitive and Physical Function
Nidadavolu, L. S., Feger, D., Wu, Y., Grodstein, F., Gross, A. L., Bennett, D. A., Walston, J. D., Oh, E. S. & Abadir, P. M., 2022, In: Journal of Alzheimer's Disease. 89, 4, p. 1233-1240 8 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Genome-Wide Analysis in Drosophila Reveals the Genetic Basis of Variation in Age-Specific Physical Performance and Response to ACE Inhibition
Gabrawy, M. M., Khosravian, N., Morcos, G. S., Morozova, T. V., Jezek, M., Walston, J. D., Huang, W., Abadir, P. M. & Leips, J., Jan 2022, In: Genes. 13, 1, 143.Research output: Contribution to journal › Article › peer-review
Open Access -
Higher Angiotensin II Type 1 Receptor Levels and Activity in the Postmortem Brains of Older Persons with Alzheimer's Dementia
Cosarderelioglu, C., Nidadavolu, L. S., George, C. J., Marx-Rattner, R., Powell, L., Xue, Q. L., Tian, J., Salib, J., Oh, E. S., Ferrucci, L., Dincer, P., Bennett, D. A., Walston, J. D. & Abadir, P. M., Apr 1 2022, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 77, 4, p. 664-672 9 p.Research output: Contribution to journal › Article › peer-review
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Losartan Mitigates Oxidative Stress in the Brains of Aged and Inflamed IL-10-/-Mice
Saleh, N., Cosarderelioglu, C., Vajapey, R., Walston, J. & Abadir, P. M., Sep 1 2022, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 77, 9, p. 1784-1788 5 p.Research output: Contribution to journal › Article › peer-review
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Metabolomics-Based Identification of Metabolic Dysfunction in Frailty
Westbrook, R., Zhang, C., Yang, H., Tian, J., Guo, S., Xue, Q. L., Walston, J., Le, A. & Abadir, P. M., Dec 1 2022, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 77, 12, p. 2367-2372 6 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Metabolomics Captures the Biological Signatures of Aging and Health Span and Identifies Pathway Targets for Intervention
Westbrook, R. & Abadir, P. M., Dec 1 2022, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 77, 12, p. 2343-2345 3 p.Research output: Contribution to journal › Article › peer-review
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Nature-inspired delivery of mitochondria-targeted angiotensin receptor blocker
Phillip, J. M., Lin, R., Cheetham, A., Stern, D., Li, Y., Wang, Y., Wang, H., Rini, D., Cui, H., Walston, J. D. & Abadir, P. M., Sep 1 2022, In: PNAS Nexus. 1, 4, pgac147.Research output: Contribution to journal › Article › peer-review
Open Access -
Serum Concentrations of Losartan Metabolites Correlate With Improved Physical Function in a Pilot Study of Prefrail Older Adults
Lee, J. L., Zhang, C., Westbrook, R., Gabrawy, M. M., Nidadavolu, L., Yang, H., Marx, R., Wu, Y., Anders, N. M., Ma, L., Bichara, M. D., Kwak, M. J., Buta, B., Khadeer, M., Yenokyan, G., Tian, J., Xue, Q. L., Siragy, H. M., Carey, R. M., De Cabo, R., & 6 others, Dec 1 2022, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 77, 12, p. 2356-2366 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Valsartan and sacubitril combination treatment enhances collagen production in older adult human skin cells
Marin, S., Godet, I., Nidadavolu, L. S., Tian, J., Dickinson, L. E., Walston, J. D., Gilkes, D. M. & Abadir, P. M., Aug 2022, In: Experimental Gerontology. 165, 111835.Research output: Contribution to journal › Article › peer-review
Open Access -
2021
Lactoferrin for the treatment of age-associated inflammation – A pilot study
Laskow, T., Langdon, J., Abadir, P., Xue, Q. L. & Walston, J., Mar 2021, In: Physiology International. 108, 1, p. 121-136 16 p.Research output: Contribution to journal › Article › peer-review
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Targeted deletion of interleukin-6 in a mouse model of chronic inflammation demonstrates opposing roles in aging: Benefit and harm
Ma, L., Nidadavolu, L. S., Yang, H., Langdon, J., Westbrook, R., Tsui, B. M. W., Lee, T. S., Hinson, J., Ling, S., Marx-Rattner, R., Wu, Y., Nguyen, T., Tan, J., Khadeer, M., Moaddel, R., Le, A., Walston, J. D. & Abadir, P. M., Feb 1 2021, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 76, 2, p. 211-215 5 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Valsartan nano-filaments alter mitochondrial energetics and promote faster healing in diabetic rat wounds
Nidadavolu, L. S., Stern, D., Lin, R., Wang, Y., Li, Y., Wu, Y., Marin, S., Antonio, M. J., Yenokyan, G., Boronina, T., Cole, R., Foster, D. B., Talbot, C. C., Jedrych, J., Smith, B., Rini, D., Le, A., Cui, H., Walston, J. D. & Abadir, P. M., Nov 1 2021, In: Wound Repair and Regeneration. 29, 6, p. 927-937 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2020
Age, Frailty, and Impaired Wound Healing
Gould, L. J., Abadir, P. M. & Foy White-Chu, E., Jan 1 2020, Principles and Practice of Geriatric Surgery: Third Edition: With 261 Figures and 155 Tables. Springer International Publishing, p. 465-482 18 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Brain Renin–Angiotensin System at the Intersect of Physical and Cognitive Frailty
Cosarderelioglu, C., Nidadavolu, L. S., George, C. J., Oh, E. S., Bennett, D. A., Walston, J. D. & Abadir, P. M., Sep 30 2020, In: Frontiers in Neuroscience. 14, 586314.Research output: Contribution to journal › Review article › peer-review
Open Access3 Scopus citations -
Kynurenines link chronic inflammation to functional decline and physical frailty
Westbrook, R., Chung, T., Lovett, J., Ward, C., Joca, H., Yang, H., Khadeer, M., Tian, J., Xue, Q. L., Le, A., Ferrucci, L., Moaddel, R., de Cabo, R., Hoke, A., Walston, J. & Abadir, P. M., Aug 20 2020, In: JCI Insight. 5, 16, e136091.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Plasma levels of corticosterone, tumor necrosis factor receptor 1 and interleukin 6 are influenced by age, sex and chronic inflammation in mice treated with acute temperature stress
Ge, N., Westbrook, R., Langdon, J., Yang, H., Marx, R., Abadir, P., Xue, Q. L. & Walston, J. D., Dec 2020, In: Experimental Gerontology. 142, 111136.Research output: Contribution to journal › Article › peer-review
Open Access -
2019
Lisinopril Preserves Physical Resilience and Extends Life Span in a Genotype-Specific Manner in Drosophila melanogaster
Gabrawy, M. M., Campbell, S., Carbone, M. A., Morozova, T. V., Arya, G. H., Turlapati, L. B., Walston, J. D., Starz-Gaiano, M., Everett, L., Mackay, T. F. C., Leips, J. & Abadir, P. M., Nov 13 2019, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 74, 12, p. 1844-1852 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
When Women Rise, We All Rise: American Geriatrics Society Position Statement on Achieving Gender Equity in Geriatrics
Boxer, R., Norman, M., Abadir, P., Beizer, J. L., Dierich, M., Lau, S., Linnebur, S. A., Lundebjerg, N. E., Naik, A. D., Schreiber, R., Unroe, K., Mikhailovich, A. L. & Goldstein, A. C., Dec 1 2019, In: Journal of the American Geriatrics Society. 67, 12, p. 2447-2454 8 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
2018
Age-and genotype-specific effects of the angiotensin-converting enzyme inhibitor lisinopril on mitochondrial and metabolic parameters in drosophila melanogaster
Ederer, K. A., Jin, K., Bouslog, S., Wang, L., Gorman, G. S., Rowe, G. C., Abadir, P., Raftery, D., Moellering, D., Promislow, D., Jumbo-Lucioni, P. & De Luca, M., Nov 2018, In: International journal of molecular sciences. 19, 11, 3351.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Report and Research Agenda of the American Geriatrics Society and National Institute on Aging Bedside-to-Bench Conference on Urinary Incontinence in Older Adults: A Translational Research Agenda for a Complex Geriatric Syndrome
the American Geriatrics Society/National Institute on Aging Urinary Incontinence Conference Planning Committee and Faculty, Apr 2018, In: Journal of the American Geriatrics Society. 66, 4, p. 773-782 10 p.Research output: Contribution to journal › Review article › peer-review
Open Access15 Scopus citations -
Topical Reformulation of Valsartan for Treatment of Chronic Diabetic Wounds
Abadir, P., Hosseini, S., Faghih, M., Ansari, A., Lay, F., Smith, B., Beselman, A., Vuong, D., Berger, A., Tian, J., Rini, D., Keenahan, K., Budman, J., Inagami, T., Fedarko, N., Marti, G., Harmon, J. & Walston, J., Feb 2018, In: Journal of Investigative Dermatology. 138, 2, p. 434-443 10 p.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
2017
Co-Localization of Macrophage Inhibitory Factor and Nix in Skeletal Muscle of the Aged Male Interleukin 10 Null Mouse
Abadir, P., Ko, F., Marx, R., Powell, L., Kieserman, E., Yang, H. & Walston, J., 2017, In: The Journal of frailty & aging. 6, 3, p. 118-121 4 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Discovery and Validation of Agonistic Angiotensin Receptor Autoantibodies as Biomarkers of Adverse Outcomes
Abadir, P. M., Jain, A., Powell, L. J., Xue, Q. L., Tian, J., Hamilton, R. G., Bennett, D. A., Finucane, T., Walston, J. D. & Fedarko, N. S., Jan 31 2017, In: Circulation. 135, 5, p. 449-459 11 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
2016
Impaired mitochondrial degradation by autophagy in the skeletal muscle of the aged female interleukin 10 null mouse
Ko, F., Abadir, P., Marx, R., Westbrook, R., Cooke, C., Yang, H. & Walston, J., Jan 1 2016, In: Experimental Gerontology. 73, p. 23-27 5 p.Research output: Contribution to journal › Article › peer-review
Open Access29 Scopus citations -
Rapamycin increases grip strength and attenuates age-related decline in maximal running distance in old low capacity runner rats
Xue, Q. L., Yang, H., Li, H. F., Abadir, P. M., Burks, T. N., Koch, L. G., Britton, S. L., Carlson, J., Chen, L., Walston, J. D. & Leng, S. X., 2016, In: Aging. 8, 4, p. 769-776 8 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
2015
Angiotensin type 1 receptor mediates renal production and conversion of prostaglandins E2 to F2α in conscious diabetic rats
Abadir, P. M. & Siragy, H. M., Dec 1 2015, In: JRAAS - Journal of the Renin-Angiotensin-Aldosterone System. 16, 4, p. 774-779 6 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Chronic wound repair and healing in older adults: Current status and future research
Gould, L., Abadir, P., Brem, H., Carter, M., Conner-Kerr, T., Davidson, J., Dipietro, L., Falanga, V., Fife, C., Gardner, S., Grice, E., Harmon, J., Hazzard, W. R., High, K. P., Houghton, P., Jacobson, N., Kirsner, R. S., Kovacs, E. J., Margolis, D., McFarland Horne, F., & 9 others, Jan 1 2015, In: Wound Repair and Regeneration. 23, 1, p. 1-13 13 p.Research output: Contribution to journal › Review article › peer-review
Open Access83 Scopus citations -
Chronic wound repair and healing in older adults: Current status and future research
Gould, L., Abadir, P., Brem, H., Carter, M., Conner-Kerr, T., Davidson, J., Dipietro, L., Falanga, V., Fife, C., Gardner, S., Grice, E., Harmon, J., Hazzard, W. R., High, K. P., Houghton, P., Jacobson, N., Kirsner, R. S., Kovacs, E. J., Margolis, D., McFarland Horne, F., & 9 others, Mar 1 2015, In: Journal of the American Geriatrics Society. 63, 3, p. 427-438 12 p.Research output: Contribution to journal › Article › peer-review
115 Scopus citations -
Combined effects of aging and inflammation on renin-angiotensin system mediate mitochondrial dysfunction and phenotypic changes in cardiomyopathies
Burks, T. N., Marx, R., Powell, L., Rucker, J., Bedja, D., Heacock, E., Smith, B. J., Brian Foster, D., Kass, D., O'Rourke, B., Walston, J. D. & Abadir, P. M., 2015, In: Oncotarget. 6, 14, p. 11979-11993 15 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Dual peptide conjugation strategy for improved cellular uptake and mitochondria targeting
Lin, R., Zhang, P., Cheetham, A. G., Walston, J., Abadir, P. & Cui, H., Jan 21 2015, In: Bioconjugate Chemistry. 26, 1, p. 71-77 7 p.Research output: Contribution to journal › Article › peer-review
Open Access46 Scopus citations -
Failure of Glucose Monitoring in an Individual with Pseudohypoglycemia
Lee, K. T. & Abadir, P. M., Aug 1 2015, In: Journal of the American Geriatrics Society. 63, 8, p. 1706-1708 3 p.Research output: Contribution to journal › Letter › peer-review
Open Access3 Scopus citations -
Knockout of Angiotensin AT2 receptors accelerates healing but impairs quality
Faghih, M., Hosseini, S. M., Smith, B., Ansari, A. M., Lay, F., Ahmed, A. K., Inagami, T., Marti, G. P., Harmon, J. W., Walston, J. D. & Abadir, P. M., 2015, In: Aging. 7, 12, p. 1185-1197 13 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
2014
Losartan improves measures of activity, inflammation, and oxidative stress in older mice
Lin, C. H., Yang, H., Xue, Q. L., Chuang, Y. F., Roy, C. N., Abadir, P. & Walston, J. D., Oct 2014, In: Experimental Gerontology. 58, p. 174-178 5 p.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations