Research Output 2003 2018

2018

Topical Reformulation of Valsartan for Treatment of Chronic Diabetic Wounds

Abadir, P., Hosseini, S., Faghih, M., Ansari, A., Lay, F., Smith, B., Beselman, A., Vuong, D., Berger, A., Tian, J., Rini, D., Keenahan, K., Budman, J., Inagami, T., Fedarko, N., Marti, G., Harmon, J. & Walston, J. Feb 1 2018 In : Journal of Investigative Dermatology. 138, 2, p. 434-443 10 p.

Research output: Contribution to journalArticle

Valsartan
Angiotensins
Smad Proteins
Wound Healing
Angiotensin II Type 1 Receptor Blockers
2017

Co-Localization of Macrophage Inhibitory Factor and Nix in Skeletal Muscle of the Aged Male Interleukin 10 Null Mouse

Abadir, P., Ko, F., Marx, R., Powell, L., Kieserman, E., Yang, H. & Walston, J. Jan 1 2017 In : The Journal of frailty & aging. 6, 3, p. 118-121 4 p.

Research output: Contribution to journalArticle

Interleukin-10
Skeletal Muscle
Macrophages
Inflammation
Proteins

Discovery and Validation of Agonistic Angiotensin Receptor Autoantibodies as Biomarkers of Adverse Outcomes

Abadir, P. M., Jain, A., Powell, L. J., Xue, Q. L., Tian, J., Hamilton, R. G., Bennett, D. A., Finucane, T., Walston, J. D. & Fedarko, N. S. Jan 31 2017 In : Circulation. 135, 5, p. 449-459 11 p.

Research output: Contribution to journalArticle

Angiotensin Type 1 Receptor
Angiotensin Receptors
Autoantibodies
Biomarkers
Angiotensin Receptor Antagonists
2016

Impaired mitochondrial degradation by autophagy in the skeletal muscle of the aged female interleukin 10 null mouse

Ko, F., Abadir, P., Marx, R., Westbrook, R., Cooke, C., Yang, H. & Walston, J. Jan 1 2016 In : Experimental Gerontology. 73, p. 23-27 5 p.

Research output: Contribution to journalArticle

Mitochondrial Degradation
Autophagy
Interleukin-10
Muscle
Skeletal Muscle

Rapamycin increases grip strength and attenuates age-related decline in maximal running distance in old low capacity runner rats

Xue, Q. L., Yang, H., Li, H. F., Abadir, P. M., Burks, T. N., Koch, L. G., Britton, S. L., Carlson, J., Chen, L., Walston, J. D. & Leng, S. X. Apr 1 2016 In : Aging. 8, 4, p. 769-776 8 p.

Research output: Contribution to journalArticle

Hand Strength
Sirolimus
Running
Placebos
Diet
2015
Angiotensin Type 1 Receptor
Prostaglandins E
Prostaglandins F
Kidney
prostaglandin-E2 9-reductase

Chronic wound repair and healing in older adults: Current status and future research

Gould, L. , Abadir, P. , Brem, H. , Carter, M. , Conner-Kerr, T. , Davidson, J. , Dipietro, L. , Falanga, V. , Fife, C. , Gardner, S. , Grice, E. , Harmon, J. , Hazzard, W. R. , High, K. P. , Houghton, P. , Jacobson, N. , Kirsner, R. S. , Kovacs, E. J. , Margolis, D. , McFarland Horne, F. & 9 others Reed, M. J., Sullivan, D. H., Thom, S., Tomic-Canic, M., Walston, J., Whitney, J. A., Williams, J., Zieman, S. & Schmader, K. Mar 1 2015 In : Journal of the American Geriatrics Society. 63, 3, p. 427-438 12 p.

Research output: Contribution to journalArticle

Wound Healing
Wounds and Injuries
National Institute on Aging (U.S.)
Research
Comorbidity

Chronic wound repair and healing in older adults: Current status and future research

Gould, L. , Abadir, P. , Brem, H. , Carter, M. , Conner-Kerr, T. , Davidson, J. , Dipietro, L. , Falanga, V. , Fife, C. , Gardner, S. , Grice, E. , Harmon, J. , Hazzard, W. R. , High, K. P. , Houghton, P. , Jacobson, N. , Kirsner, R. S. , Kovacs, E. J. , Margolis, D. , McFarland Horne, F. & 9 others Reed, M. J., Sullivan, D. H., Thom, S., Tomic-Canic, M., Walston, J., Whitney, J., Williams, J., Zieman, S. & Schmader, K. Jan 1 2015 In : Wound Repair and Regeneration. 23, 1, p. 1-13 13 p.

Research output: Contribution to journalArticle

Wound Healing
Wounds and Injuries
National Institute on Aging (U.S.)
Research
Randomized Controlled Trials

Combined effects of aging and inflammation on renin-angiotensin system mediate mitochondrial dysfunction and phenotypic changes in cardiomyopathies

Burks, T. N., Marx, R., Powell, L., Rucker, J., Bedja, D., Heacock, E., Smith, B. J., Brian Foster, D., Kass, D., O'Rourke, B., Walston, J. D. & Abadir, P. M. 2015 In : Oncotarget. 6, 14, p. 11979-11993 15 p.

Research output: Contribution to journalArticle

Renin-Angiotensin System
Cardiomyopathies
Inflammation
Myocardium
Premature Aging

Dual peptide conjugation strategy for improved cellular uptake and mitochondria targeting

Lin, R., Zhang, P., Cheetham, A. G., Walston, J., Abadir, P. & Cui, H. Jan 21 2015 In : Bioconjugate Chemistry. 26, 1, p. 71-77 7 p.

Research output: Contribution to journalArticle

Mitochondria
Peptides
Cell-Penetrating Peptides
Molecules
Cell membranes

Failure of Glucose Monitoring in an Individual with Pseudohypoglycemia

Lee, K. T. & Abadir, P. M. Aug 1 2015 In : Journal of the American Geriatrics Society. 63, 8, p. 1706-1708 3 p.

Research output: Contribution to journalArticle

Blood Glucose Self-Monitoring
Raynaud Disease
Regional Blood Flow
Microcirculation
Diagnostic Errors

Knockout of Angiotensin AT2 receptors accelerates healing but impairs quality

Faghih, M., Hosseini, S. M., Smith, B., Ansari, A. M., Lay, F., Ahmed, A. K., Inagami, T., Marti, G. P., Harmon, J. W., Walston, J. D. & Abadir, P. M. 2015 In : Aging. 7, 12, p. 1185-1197 13 p.

Research output: Contribution to journalArticle

Angiotensins
Wound Healing
Wounds and Injuries
Angiotensin Type 2 Receptor
Skin
2014

Losartan improves measures of activity, inflammation, and oxidative stress in older mice

Lin, C. H., Yang, H., Xue, Q. L., Chuang, Y. F., Roy, C. N., Abadir, P. & Walston, J. D. 2014 In : Experimental Gerontology. 58, p. 174-178 5 p.

Research output: Contribution to journalArticle

Oxidative stress
Losartan
Oxidative Stress
Inflammation
Angiotensins
Angiotensins
Renin-Angiotensin System
Angiotensin II
Free Radicals
Reactive Oxygen Species
2013

The unknown profession: A geriatrician

Campbell, J. Y., Durso, S. C., Brandt, L. E., Finucane, T. E. & Abadir, P. M. Mar 2013 In : Journal of the American Geriatrics Society. 61, 3, p. 447-449 3 p.

Research output: Contribution to journalArticle

Geriatrics
Ice Cream
Baltimore
Quality of Health Care
Public Health
2012

Subcellular characteristics of functional intracellular renin-angiotensin systems

Abadir, P. M., Walston, J. D. & Carey, R. M. Dec 2012 In : Peptides. 38, 2, p. 437-445 9 p.

Research output: Contribution to journalArticle

Angiotensins
Renin-Angiotensin System
Renin
Angiotensin I
Angiotensinogen
2011
STAT Transcription Factors
Angiotensin Type 2 Receptor
STAT3 Transcription Factor
Phosphorylation
Inflammation

Identification and characterization of a functional mitochondrial angiotensin system

Abadir, P. M., Foster, D. B., Crow, M., Cooke, C. A., Rucker, J. J., Jain, A., Smith, B. J., Burks, T. N., Cohn, R. D., Fedarko, N. S., Carey, R. M., O'Rourke, B. & Walston, J. D. Sep 6 2011 In : Proceedings of the National Academy of Sciences of the United States of America. 108, 36, p. 14849-14854 6 p.

Research output: Contribution to journalArticle

Angiotensins
Angiotensin Receptors
Angiotensin Type 1 Receptor
Renin-Angiotensin System
Mitochondria

Intrinsic aerobic capacity sets a divide for aging and longevity

Koch, L. G., Kemi, O. J., Qi, N., Leng, S. X., Bijma, P., Gilligan, L. J., Wilkinson, J. E., Wisløff, H., Høydal, M. A., Rolim, N., Abadir, P. M., Van Grevenhof, E. M., Smith, G. L., Burant, C. F., Ellingsen, Ø., Britton, S. L. & Wisløff, U. Oct 28 2011 In : Circulation Research. 109, 10, p. 1162-1172 11 p.

Research output: Contribution to journalArticle

Exercise
Premature Mortality
Running
Walking
Cardiovascular Diseases

The Frail Renin-Angiotensin System

Abadir, P. M. Feb 2011 In : Clinics in Geriatric Medicine. 27, 1, p. 53-65 13 p.

Research output: Contribution to journalArticle

Renin-Angiotensin System
Angiotensin II
Blood Vessels
Angiotensin Type 2 Receptor
Angiotensin Type 1 Receptor
Advance Directive Adherence
Life Support Care
Dissent and Disputes
Nuclear Family
2008
12-Hydroxy-5,8,10,14-eicosatetraenoic Acid
Angiotensin Type 2 Receptor
Angiotensin Type 1 Receptor
Valsartan
Kidney
2006

Angiotensin II type 2 receptor-bradykinin B2 receptor functional heterodimerization

Abadir, P. M., Periasamy, A., Carey, R. M. & Siragy, H. M. Aug 2006 In : Hypertension. 48, 2, p. 316-322 7 p.

Research output: Contribution to journalArticle

Activating Transcription Factor 2
Angiotensin Type 2 Receptor
Bradykinin B2 Receptors
Fluorescence Resonance Energy Transfer
Protein Tyrosine Phosphatases
2005

Angiotensin subtype-2 receptors inhibit renin biosynthesis and angiotensin II formation

Siragy, H. M., Xue, C., Abadir, P. & Carey, R. M. Jan 2005 In : Hypertension. 45, 1, p. 133-137 5 p.

Research output: Contribution to journalArticle

Angiotensins
Renin
Angiotensin II
Valsartan
Sodium
2003

Angiotensin AT2 receptors directly stimulate renal nitric oxide in Bradykinin B2-receptor-null mice

Abadir, P. M., Carey, R. M. & Siragy, H. M. Oct 1 2003 In : Hypertension. 42, 4 I, p. 600-604 5 p.

Research output: Contribution to journalArticle

Angiotensin Type 2 Receptor
Bradykinin B2 Receptors
Nitric Oxide
Kidney
Valsartan

The angiotensin II type 1 receptor mediates renal interstitial content of tumor necrosis factor-α in diabetic rats

Siragy, H. M., Awad, A., Abadir, P. & Webb, R. Jun 1 2003 In : Endocrinology. 144, 6, p. 2229-2233 5 p.

Research output: Contribution to journalArticle

Valsartan
Angiotensin Type 1 Receptor
Angiotensin II
Tumor Necrosis Factor-alpha
Kidney