Paul B Rothman

Professor

1982 …2018

Research output per year

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Research Output

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2018

Association of a Care Coordination Model With Health Care Costs and Utilization: The Johns Hopkins Community Health Partnership (J-CHiP)

Johns Hopkins Community Health Partnership (J-CHiP) Team, Nov 2 2018, In : JAMA Network Open. 1, 7, p. e184273

Research output: Contribution to journalArticle

Open Access

Next level of board accountability in health care quality

Pronovost, P. J., Demski, R., Armstrong, C. M., Peterson, R. R. & Rothman, P. B., Jan 2 2018, (Accepted/In press) In : Journal of Health, Organisation and Management.

Research output: Contribution to journalArticle

2016

Case Study: Johns Hopkins Community Health Partnership: A model for transformation

Berkowitz, S. A., Brown, P., Brotman, D. J., Deutschendorf, A., Dunbar, L., Everett, A., Hickman, D., Howell, E., Purnell, L., Sylvester, C., Zollinger, R., Bellantoni, M., Durso, S. C., Lyketsos, C. & Rothman, P., Feb 8 2016, (Accepted/In press) In : Healthcare.

Research output: Contribution to journalArticle

Dok-1 negatively regulates platelet integrin αIIbβ3 outside-in signalling and inhibits thrombosis in mice

Niki, M., Nayak, M. K., Jin, H., Bhasin, N., Plow, E. F., Pandolfi, P. P., Rothman, P. B., Chauhan, A. K. & Lentz, S. R., May 2016, In : Thrombosis and Haemostasis. 115, 5, p. 969-978 10 p.

Research output: Contribution to journalArticle

Introduction of Peter Agre

Rothman, P. B., Dec 1 2016, In : Journal of Clinical Investigation. 126, 12, p. 4735-4741 7 p.

Research output: Contribution to journalArticle

2015

Creating a high-reliability health care system: Improving performance on core processes of care at johns hopkins medicine

Pronovost, P. J., Armstrong, C. M., Demski, R., Callender, T., Winner, L., Miller, M. R., Austin, J. M., Berenholtz, S. M., Yang, T., Peterson, R. R., Reitz, J. A., Bennett, R. G., Broccolino, V. A., Davis, R. O., Gragnolati, B. A., Green, G. E. & Rothman, P. B., Feb 6 2015, In : Academic Medicine. 90, 2, p. 165-172 8 p.

Research output: Contribution to journalArticle

Intestinal helminths regulate lethal acute graft-versus-host disease and preserve the graft-versus-tumor effect in mice

Li, Y., Chen, H. L., Bannick, N., Henry, M., Holm, A. N., Metwali, A., Urban, J. F., Rothman, P. B., Weiner, G. J., Blazar, B. R., Elliott, D. E. & Ince, M. N., Feb 1 2015, In : Journal of Immunology. 194, 3, p. 1011-1020 10 p.

Research output: Contribution to journalArticle

2014

NFIL3-deficient mice develop microbiota-dependent, IL-12/23-driven spontaneous colitis

Kobayashi, T., Steinbach, E. C., Russo, S. M., Matsuoka, K., Nochi, T., Maharshak, N., Borst, L. B., Hostager, B., Garcia-Martinez, J. V., Rothman, P. B., Kashiwada, M., Sheikh, S. Z., Murray, P. J. & Plevy, S. E., Feb 15 2014, In : Journal of Immunology. 192, 4, p. 1918-1927 10 p.

Research output: Contribution to journalArticle

Tim-3 directly enhances CD8 T cell responses to acute Listeria monocytogenes infection

Gorman, J. V., Starbeck-Miller, G., Pham, N. L. L., Traver, G. L., Rothman, P. B., Harty, J. T. & Colgan, J. D., Apr 1 2014, In : Journal of Immunology. 192, 7, p. 3133-3142 10 p.

Research output: Contribution to journalArticle

Tissue-resident natural killer (NK) cells are cell lineages distinct from thymic and conventional splenic NK cells

Sojka, D. K., Plougastel-Douglas, B., Yang, L., Pak-Wittel, M. A., Artyomov, M. N., Ivanova, Y., Zhong, C., Chase, J. M., Rothman, P. B., Yu, J., Riley, J. K., Zhu, J., Tian, Z. & Yokoyama, W. M., Apr 8 2014, In : eLife. 2014, 3, e01659.

Research output: Contribution to journalArticle

2013

EIF4B phosphorylation by pim kinases plays a critical role in cellular transformation by Abl oncogenes

Yang, J., Wang, J., Chen, K., Guo, G., Xi, R., Rothman, P. B., Whitten, D., Zhang, L., Huang, S. & Chen, J. L., Aug 1 2013, In : Cancer Research. 73, 15, p. 4898-4908 11 p.

Research output: Contribution to journalArticle

Nfil3-independent lineage maintenance and antiviral response of natural killer cells

Firth, M. A., Madera, S., Beaulieu, A. M., Gasteiger, G., Castillo, E. F., Schluns, K. S., Kubo, M., Rothman, P. B., Vivier, E. & Sun, J. C., Dec 1 2013, In : Journal of Experimental Medicine. 210, 13, p. 2981-2990 10 p.

Research output: Contribution to journalArticle

Polymorphisms in the SOCS7 gene and glucose homeostasis traits

Capuano, M. M., Sorkin, J. D., Chang, Y. P. C., Ling, H., O'Connell, J. R., Rothman, P. B., Mitchell, B. D. & Silver, K. D., Jun 18 2013, In : BMC Research Notes. 6, 1, 235.

Research output: Contribution to journalArticle

TH17 cell differentiation is regulated by the circadian clock

Yu, X., Rollins, D., Ruhn, K. A., Stubblefield, J. J., Green, C. B., Kashiwada, M., Rothman, P. B., Takahashi, J. S. & Hooper, L. V., Jan 1 2013, In : Science. 342, 6159, p. 727-730 4 p.

Research output: Contribution to journalArticle

2012

A requirement for SOCS-1 and SOCS-3 phosphorylation in Bcr-Abl-induced tumorigenesis

Qiu, X., Guo, G., Chen, K., Kashiwada, M., Druker, B. J., Rothman, P. B. & Chen, J. L., Jun 2012, In : Neoplasia (United States). 14, 6, p. 547-558 12 p.

Research output: Contribution to journalArticle

Medical research has health and wealth implications.

Rothman, P., Jan 1 2012, In : Iowa medicine : journal of the Iowa Medical Society. 102, 1, 1 p.

Research output: Contribution to journalArticle

Tim-1 regulates Th2 responses in an airway hypersensitivity model

Curtiss, M. L., Gorman, J. V., Businga, T. R., Traver, G., Singh, M., Meyerholz, D. K., Kline, J. N., Murphy, A. J., Valenzuela, D. M., Colgan, J. D., Rothman, P. B. & Cassel, S. L., Mar 1 2012, In : European Journal of Immunology. 42, 3, p. 651-661 11 p.

Research output: Contribution to journalArticle

2011

A SOCS-1 promoter variant is associated with total serum IgE levels

Mostecki, J., Cassel, S. L., Klimecki, W. T., Stern, D. A., Knisz, J., Iwashita, S., Graves, P., Miller, R. L., Van Peer, M., Halonen, M., Martinez, F. D., Vercelli, D. & Rothman, P. B., Sep 1 2011, In : Journal of Immunology. 187, 5, p. 2794-2802 9 p.

Research output: Contribution to journalArticle

Changing environment, student interest curriculum.

Rothman, P., May 1 2011, In : Iowa medicine : journal of the Iowa Medical Society. 101, 3, 1 p.

Research output: Contribution to journalArticle

Fyn binds to and phosphorylates T cell immunoglobulin and mucin domain-1 (Tim-1)

Curtiss, M. L., Hostager, B. S., Stepniak, E., Singh, M., Manhica, N., Knisz, J., Traver, G., Rennert, P. D., Colgan, J. D. & Rothman, P. B., Jul 1 2011, In : Molecular Immunology. 48, 12-13, p. 1424-1431 8 p.

Research output: Contribution to journalArticle

Genomic medicine is changing health care.

Rothman, P., Jan 1 2011, In : Iowa medicine : journal of the Iowa Medical Society. 101, 1, 1 p.

Research output: Contribution to journalArticle

HOIL-1L interacting protein (HOIP) is essential for CD40 signaling

Hostager, B. S., Kashiwada, M., Colgan, J. D. & Rothman, P. B., Aug 4 2011, In : PloS one. 6, 8, e23061.

Research output: Contribution to journalArticle

New resident work rules raise questions.

Rothman, P., Jan 1 2011, In : Iowa medicine : journal of the Iowa Medical Society. 101, 5, 1 p.

Research output: Contribution to journalArticle

NFIL3/E4BP4 controls type 2 T helper cell cytokine expression

Kashiwada, M., Cassel, S. L., Colgan, J. D. & Rothman, P. B., May 18 2011, In : EMBO Journal. 30, 10, p. 2071-2082 12 p.

Research output: Contribution to journalArticle

NFIL3/E4BP4 is a key transcription factor for CD8α+ dendritic cell development

Kashiwada, M., Pham, N. L. L., Pewe, L. L., Harty, J. T. & Rothman, P. B., Jun 9 2011, In : Blood. 117, 23, p. 6193-6197 5 p.

Research output: Contribution to journalArticle

NFIL3 is a regulator of IL-12 p40 in macrophages and mucosal immunity

Kobayashi, T., Matsuoka, K., Sheikh, S. Z., Elloumi, H. Z., Kamada, N., Hisamatsu, T., Hansen, J. J., Doty, K. R., Pope, S. D., Smale, S. T., Hibi, T., Rothman, P. B., Kashiwada, M. & Plevy, S. E., Apr 15 2011, In : Journal of Immunology. 186, 8, p. 4649-4655 7 p.

Research output: Contribution to journalArticle

The developmental regulator protein Gon4l associates with protein YY1, co-repressor Sin3a, and histone deacetylase 1 and mediates transcriptional repression

Lu, P., Hankel, I. L., Hostager, B. S., Swartzendruber, J. A., Friedman, A. D., Brenton, J. L., Rothman, P. B. & Colgan, J. D., May 20 2011, In : Journal of Biological Chemistry. 286, 20, p. 18311-18319 9 p.

Research output: Contribution to journalArticle

2010

HOIL-1L interacting protein (HOIP) as an Nf-κB regulating component of the CD40 signaling complex

Hostager, B. S., Fox, D. K., Whitten, D., Wilkerson, C. G., Eipper, B. A., Francone, V. P., Rothman, P. B. & Colgan, J. D., Aug 12 2010, In : PloS one. 5, 6, e11380.

Research output: Contribution to journalArticle

Identification of DOK genes as lung tumor suppressors

Berger, A. H., Niki, M., Morotti, A., Taylor, B. S., Socci, N. D., Viale, A., Brennan, C., Szoke, J., Motoi, N., Rothman, P. B., Teruya-Feldstein, J., Gerald, W. L., Ladanyi, M. & Pandolfi, P. P., Mar 1 2010, In : Nature genetics. 42, 3, p. 216-223 8 p.

Research output: Contribution to journalArticle

IL-4-induced transcription factor NFIL3/E4BP4 controls IgE class switching

Kashiwada, M., Levy, D. M., McKeag, L., Murray, K., Schröder, A. J., Canfield, S. M., Traver, G. & Rothman, P. B., Feb 15 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 2, p. 821-826 6 p.

Research output: Contribution to journalArticle

Iowa--the bright side of health care.

Rothman, P., Jan 1 2010, In : Iowa medicine : journal of the Iowa Medical Society. 100, 1, 1 p.

Research output: Contribution to journalArticle

Oncogenic E17K mutation in the pleckstrin homology domain of AKT1 promotes v-Abl-mediated pre-B-cell transformation and survival of Pim-deficient cells

Guo, G., Qiu, X., Wang, S., Chen, Y., Rothman, P. B., Wang, Z., Chen, Y., Wang, G. & Chen, J. L., Jul 1 2010, In : Oncogene. 29, 26, p. 3845-3853 9 p.

Research output: Contribution to journalArticle

On the right track at the UI Carver College of Medicine.

Rothman, P., Jan 1 2010, In : Iowa medicine : journal of the Iowa Medical Society. 100, 5, p. 20-21 2 p.

Research output: Contribution to journalArticle

The Justy mutation identifies Gon4-like as a gene that is essential for B lymphopoiesis

Lu, P., Hankel, I. L., Knisz, J., Marquardt, A., Chiang, M. Y., Grosse, J., Constien, R., Meyer, T., Schroeder, A., Zeitlmann, L., Al-Alem, U., Friedman, A. D., Elliott, E. I., Meyerholz, D. K., Waldschmidt, T. J., Rothman, P. B. & Colgan, J. D., Jul 5 2010, In : Journal of Experimental Medicine. 207, 7, p. 1359-1367 9 p.

Research output: Contribution to journalArticle

The T cell receptor-mediated phosphorylation of Pyk2 tyrosines 402 and 580 occurs via a distinct mechanism than other receptor systems

Collins, M., Tremblay, M., Chapman, N., Curtiss, M., Rothman, P. B. & Houtman, J. C. D., Apr 1 2010, In : Journal of Leukocyte Biology. 87, 4, p. 691-701 11 p.

Research output: Contribution to journalArticle

2009

Key areas of health care reform of special interest to Iowa.

Rothman, P., Jan 1 2009, In : Iowa medicine : journal of the Iowa Medical Society. 99, 3, 1 p.

Research output: Contribution to journalArticle

Loss of SOCS7 in mice results in severe cutaneous disease and increased mast cell activation

Knisz, J., Banks, A., McKeag, L., Metcalfe, D. D., Rothman, P. B. & Brown, J. M., Aug 1 2009, In : Clinical Immunology. 132, 2, p. 277-284 8 p.

Research output: Contribution to journalArticle

The health care reform debate.

Rothman, P., Jan 1 2009, In : Iowa medicine : journal of the Iowa Medical Society. 99, 5, 1 p.

Research output: Contribution to journalArticle

2008

A full agenda for all of us.

Rothman, P., Jan 1 2008, In : Iowa medicine : journal of the Iowa Medical Society. 98, 5, 1 p.

Research output: Contribution to journalArticle

Pim-1 and Pim-2 kinases are required for efficient pre-B-cell transformation by v-Abl oncogene

Chen, J. L., Limnander, A. & Rothman, P. B., Feb 12 2008, In : Blood. 111, 3, p. 1677-1685 9 p.

Research output: Contribution to journalArticle

The Nalp3 inflammasome is essential for the development of silicosis

Cassel, S. L., Eisenbarth, S. C., Iyer, S. S., Sadler, J. J., Colegio, O. R., Tephly, L. A., Carter, A. B., Rothman, P. B., Flavell, R. A. & Sutterwala, F. S., Jul 1 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 26, p. 9035-9040 6 p.

Research output: Contribution to journalArticle

2007

Antigen-specific immune responses to influenza vaccine in utero

Rastogi, D., Wang, C., Mao, X., Lendor, C., Rothman, P. B. & Miller, R. L., Jun 1 2007, In : Journal of Clinical Investigation. 117, 6, p. 1637-1646 10 p.

Research output: Contribution to journalArticle

2006

All in the family: IL-27 suppression of TH-17 cells

Colgan, J. & Rothman, P., Sep 1 2006, In : Nature Immunology. 7, 9, p. 899-901 3 p.

Research output: Contribution to journalArticle

Downstream of tyrosine kinases-1 and Src homology 2-containing inositol 5′-phosphatase are required for regulation of CD4+CD25 + T cell development

Kashiwada, M., Cattoretti, G., McKeag, L., Rouse, T., Showalter, B. M., Al-Alem, U., Niki, M., Pandolfi, P. P., Field, E. H. & Rothman, P. B., Apr 1 2006, In : Journal of Immunology. 176, 7, p. 3958-3965 8 p.

Research output: Contribution to journalArticle

Open Access

T-helper type 2 polarization among asthmatics during and following pregnancy

Rastogi, D., Wang, C., Lendor, C., Rothman, P. B. & Miller, R. L., Jul 1 2006, In : Clinical and Experimental Allergy. 36, 7, p. 892-898 7 p.

Research output: Contribution to journalArticle

2005

Cutting edge: IL-4 induces suppressor of cytokine signaling-3 expression in B cells by a mechanism dependent on activation of p38 MAPK

Canfield, S., Lee, Y., Schröder, A. & Rothman, P., Mar 1 2005, In : Journal of Immunology. 174, 5, p. 2494-2498 5 p.

Research output: Contribution to journalArticle

Open Access

Deletion of SOCS7 leads to enhanced insulin action and enlarged islets of Langerhans

Banks, A. S., Li, J., McKeag, L., Hribal, M. L., Kashiwada, M., Accili, D. & Rothman, P. B., Sep 1 2005, In : Journal of Clinical Investigation. 115, 9, p. 2462-2471 10 p.

Research output: Contribution to journalArticle

Dok1 and SHIP act as negative regulators of v-Abl-induced pre-B cell transformation, proliferation and Ras/Erk activation

Oki, S., Limnander, A., Pin, M. Y., Niki, M., Pandolfi, P. P. & Rothman, P. B., Feb 2005, In : Cell Cycle. 4, 2, p. 309-313 5 p.

Research output: Contribution to journalArticle

Early growth response-1 regulates lipopolysaccharide-induced suppressor of cytokine signaling-1 transcription

Mostecki, J., Showalter, B. M. & Rothman, P. B., Jan 28 2005, In : Journal of Biological Chemistry. 280, 4, p. 2596-2605 10 p.

Research output: Contribution to journalArticle