Research output per year
Research output per year
- 1 - 50 out of 160 results
Search results
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2023
Fatty acids: Metabolism
Watkins, P. A., Jan 1 2023, Encyclopedia of Human Nutrition: Volume 1-4, Fourth Edition. Elsevier, Vol. 1-4. p. 316-329 14 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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2022
Nervonic Acid Attenuates Accumulation of Very Long-Chain Fatty Acids and is a Potential Therapy for Adrenoleukodystrophy
Terluk, M. R., Tieu, J., Sahasrabudhe, S. A., Moser, A., Watkins, P. A., Raymond, G. V. & Kartha, R. V., Apr 2022, In: Neurotherapeutics. 19, 3, p. 1007-1017 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2021
Drug discovery for X-linked adrenoleukodystrophy: An unbiased screen for compounds that lower very long-chain fatty acids
Moser, A. B., Liu, Y., Shi, X., Schrifl, U., Hiebler, S., Fatemi, A., Braverman, N. E., Steinberg, S. J. & Watkins, P. A., Oct 2021, In: Journal of cellular biochemistry. 122, 10, p. 1337-1349 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Lipids | Fatty Acyl-CoA synthetases
Watkins, P. A., Jul 29 2021, Encyclopedia of Biological Chemistry: Third Edition. Elsevier, Vol. 1. p. 472-477 6 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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2020
CTRP12 inhibits triglyceride synthesis and export in hepatocytes by suppressing HNF-4α and DGAT2 expression
Tan, S. Y., Little, H. C., Sarver, D. C., Watkins, P. A. & Wong, G. W., Oct 1 2020, In: FEBS Letters. 594, 19, p. 3227-3239 13 p.Research output: Contribution to journal › Letter › peer-review
4 Scopus citations -
Loss- or Gain-of-Function Mutations in ACOX1 Cause Axonal Loss via Different Mechanisms
Members of Undiagnosed Diseases Network, May 20 2020, In: Neuron. 106, 4, p. 589-606.e6Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
2018
Addressing medical students’ negative bias toward patients with obesity through ethics education
Geller, G. & Watkins, P. A., Oct 2018, In: AMA Journal of Ethics. 20, 10, p. 948-959 12 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Dendrimer–N-acetyl-L-cysteine modulates monophagocytic response in adrenoleukodystrophy
Turk, B. R., Nemeth, C. L., Marx, J. S., Tiffany, C., Jones, R., Theisen, B., Kambhampati, S., Ramireddy, R., Singh, S., Rosen, M., Kaufman, M. L., Murray, C. F., Watkins, P. A., Kannan, S., Kannan, R. & Fatemi, A., Sep 2018, In: Annals of neurology. 84, 3, p. 452-462 11 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Krüppel-like factor 4 (KLF4) induces mitochondrial fusion and increases spare respiratory capacity of human glioblastoma cells
Wang, S., Shi, X., Wei, S., Ma, D., Oyinlade, O., Lv, S. Q., Ying, M., Zhang, Y. A., Claypool, S. M., Watkins, P. & Xia, S., Apr 27 2018, In: Journal of Biological Chemistry. 293, 17, p. 6544-6555 12 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
2017
Antioxidant capacity and superoxide dismutase activity in adrenoleukodystrophy
Turk, B. R., Theisen, B. E., Nemeth, C. L., Marx, J. S., Shi, X., Rosen, M., Jones, R. O., Moser, A. B., Watkins, P. A., Raymond, G. V., Tiffany, C. & Fatemi, A., May 2017, In: JAMA Neurology. 74, 5, p. 519-524 6 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
The Mammalian Malonyl-CoA Synthetase ACSF3 Is Required for Mitochondrial Protein Malonylation and Metabolic Efficiency
Bowman, C. E., Rodriguez, S., Selen Alpergin, E. S., Acoba, M. G., Zhao, L., Hartung, T., Claypool, S. M., Watkins, P. A. & Wolfgang, M. J., Jun 22 2017, In: Cell Chemical Biology. 24, 6, p. 673-684.e4Research output: Contribution to journal › Article › peer-review
Open Access33 Scopus citations -
2016
Chlamydia trachomatis growth and development requires the activity of host Long-chain Acyl-CoA Synthetases (ACSLs)
Recuero-Checa, M. A., Sharma, M., Lau, C., Watkins, P. A., Gaydos, C. A. & Dean, D., Mar 18 2016, In: Scientific reports. 6, 23148.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
2014
Effects of hematopoietic stem cell transplantation on acyl-CoA oxidase deficiency: a sibling comparison study
Wang, R. Y., Monuki, E. S., Powers, J., Schwartz, P. H., Watkins, P. A., Shi, Y., Moser, A., Shrier, D. A., Waterham, H. R., Nugent, D. J. & Abdenur, J. E., Sep 1 2014, In: Journal of Inherited Metabolic Disease. 37, 5, p. 791-799 9 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Lipid metabolism enzyme ACSVL3 supports glioblastoma stem cell maintenance and tumorigenicity
Sun, P., Xia, S., Lal, B., Shi, X., Yang, K. S., Watkins, P. A. & Laterra, J., Jun 4 2014, In: BMC cancer. 14, 1, 401.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
The Pex1-G844D mouse: A model for mild human Zellweger spectrum disorder
Hiebler, S., Masuda, T., Hacia, J. G., Moser, A. B., Faust, P. L., Liu, A., Chowdhury, N., Huang, N., Lauer, A., Bennett, J., Watkins, P. A., Zack, D. J., Braverman, N. E., Raymond, G. V. & Steinberg, S. J., Apr 2014, In: Molecular genetics and metabolism. 111, 4, p. 522-532 11 p.Research output: Contribution to journal › Article › peer-review
Open Access30 Scopus citations -
2013
Fatty Acyl-CoA Synthetases
Watkins, P. A., Feb 15 2013, Encyclopedia of Biological Chemistry: Second Edition. Elsevier Inc., p. 290-295 6 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
1 Scopus citations -
Increased Long Chain acyl-Coa Synthetase Activity and Fatty Acid Import Is Linked to Membrane Synthesis for Development of Picornavirus Replication Organelles
Nchoutmboube, J. A., Viktorova, E. G., Scott, A. J., Ford, L. A., Pei, Z., Watkins, P. A., Ernst, R. K. & Belov, G. A., Jun 2013, In: PLoS pathogens. 9, 6, e1003401.Research output: Contribution to journal › Article › peer-review
Open Access64 Scopus citations -
Very Long-Chain Acyl-CoA Synthetase 3: Overexpression and Growth Dependence in Lung Cancer
Pei, Z., Fraisl, P., Shi, X., Gabrielson, E., Forss-Petter, S., Berger, J. & Watkins, P. A., Jul 23 2013, In: PloS one. 8, 7, e69392.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
2012
Cell proliferation and oxidative stress pathways are modified in fibroblasts from Sturge-Weber syndrome patients
Kadam, S. D., Cole, R. N., Gucek, M., Watkins, P. A. & Comi, A. M., Apr 2012, In: Archives of Dermatological Research. 304, 3, p. 229-235 7 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Fatty acids: Metabolism
Watkins, P. A., Jan 1 2012, Encyclopedia of Human Nutrition. Elsevier Inc., Vol. 2-4. p. 220-230 11 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
3 Scopus citations -
Identification and characterization of an extramitochondrial human 3-hydroxy-3-methylglutaryl-CoA lyase
Montgomery, C., Pei, Z., Watkins, P. A. & Miziorko, H. M., Sep 28 2012, In: Journal of Biological Chemistry. 287, 40, p. 33227-33236 10 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Peroxisomal acyl-CoA synthetases
Watkins, P. A. & Ellis, J. M., Sep 2012, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1822, 9, p. 1411-1420 10 p.Research output: Contribution to journal › Review article › peer-review
Open Access62 Scopus citations -
2011
Human and great ape red blood cells differ in plasmalogen levels and composition
Moser, A. B., Steinberg, S. J., Watkins, P. A., Moser, H. W., Ramaswamy, K., Siegmund, K. D., Lee, D. R., Ely, J. J., Ryder, O. A. & Hacia, J. G., 2011, In: Lipids in Health and Disease. 10, 101.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
Human fatty acid transport protein 2a/very long chain Acyl-CoA synthetase 1 (FATP2a/Acsvl1) has a preference in mediating the channeling of exogenous n-3 fatty acids into phosphatidylinositol
Melton, E. M., Cerny, R. L., Watkins, P. A., DiRusso, C. C. & Black, P. N., Sep 2 2011, In: Journal of Biological Chemistry. 286, 35, p. 30670-30679 10 p.Research output: Contribution to journal › Article › peer-review
Open Access33 Scopus citations -
Identification and characterization of new long chain Acyl-CoA dehydrogenases
He, M., Pei, Z., Mohsen, A. W., Watkins, P., Murdoch, G., Van Veldhoven, P. P., Ensenauer, R. & Vockley, J., Apr 2011, In: Molecular genetics and metabolism. 102, 4, p. 418-429 12 p.Research output: Contribution to journal › Article › peer-review
49 Scopus citations -
Peroxisomal diseases
Watkins, P. A. & Schwarz, K. B., Jan 1 2011, Liver Disease in Children, Fourth Edition. Cambridge University Press, p. 649-663 15 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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X-linked adrenoleukodystrophy: ABCD1 de novo mutations and mosaicism
Wang, Y., Busin, R., Reeves, C., Bezman, L., Raymond, G., Toomer, C. J., Watkins, P. A., Snowden, A., Moser, A., Naidu, S., Bibat, G., Hewson, S., Tam, K., Clarke, J. T. R., Charnas, L., Stetten, G., Karczeski, B., Cutting, G. & Steinberg, S., Sep 2011, In: Molecular genetics and metabolism. 104, 1-2, p. 160-166 7 p.Research output: Contribution to journal › Article › peer-review
29 Scopus citations -
2010
Identification of differences in human and great ape phytanic acid metabolism that could influence gene expression profiles and physiological functions
Watkins, P. A., Moser, A. B., Toomer, C. B., Steinberg, S. J., Moser, H. W., Karaman, M. W., Ramaswamy, K., Siegmund, K. D., Lee, D. R., Ely, J. J., Ryder, O. A. & Hacia, J. G., 2010, In: BMC Physiology. 10, 1, 19.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
2009
Acyl-CoA synthetase VL3 knockdown inhibits human glioma cell proliferation and tumorigenicity
Pei, Z., Sun, P., Huang, P., Lal, B., Laterra, J. & Watkins, P. A., Dec 15 2009, In: Cancer Research. 69, 24, p. 9175-9182 8 p.Research output: Contribution to journal › Article › peer-review
Open Access24 Scopus citations -
A PEX10 defect in a patient with no detectable defect in peroxisome assembly or metabolism in cultured fibroblasts
Steinberg, S. J., Snowden, A., Braverman, N. E., Chen, L., Watkins, P. A., Clayton, P. T., Setchell, K. D. R., Heubi, J. E., Raymond, G. V., Moser, A. B. & Moser, H. W., 2009, In: Journal of Inherited Metabolic Disease. 32, 1, p. 109-119 11 p.Research output: Contribution to journal › Article › peer-review
29 Scopus citations -
Bromocriptine administration reduces hyperphagia and adiposity and differentially affects dopamine D2 receptor and transporter binding in leptin-receptor-deficient Zucker rats and rats with diet-induced obesity
Davis, L. M., Michaelides, M., Cheskin, L. J., Moran, T. H., Aja, S., Watkins, P. A., Pei, Z., Contoreggi, C., McCullough, K., Hope, B., Wang, G. J., Volkow, N. D. & Thanos, P. K., Feb 2009, In: Neuroendocrinology. 89, 2, p. 152-162 11 p.Research output: Contribution to journal › Article › peer-review
Open Access51 Scopus citations -
2008
Very-long-chain acyl-CoA synthetases
Watkins, P. A., Jan 25 2008, In: Journal of Biological Chemistry. 283, 4, p. 1773-1777 5 p.Research output: Contribution to journal › Short survey › peer-review
104 Scopus citations -
2007
A new genetic disorder in mitochondrial fatty acid β-oxidation: ACAD9 deficiency
He, M., Rutledge, S. L., Kelly, D. R., Palmer, C. A., Murdoch, G., Majumder, N., Nicholls, R. D., Pei, Z., Watkins, P. A. & Vockley, J., Jul 2007, In: American journal of human genetics. 81, 1, p. 87-103 17 p.Research output: Contribution to journal › Article › peer-review
Open Access82 Scopus citations -
Brain uptake and utilization of fatty acids, lipids & lipoproteins: Recommendations for future research
Katz, R., Hamilton, J. A., Pownall, H. J., Deckelbaum, R. J., Hillard, C. J., LeBoeuf, R. C. & Watkins, P. A., Sep 2007, In: Journal of Molecular Neuroscience. 33, 1, p. 146-150 5 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Brain uptake and utilization of fatty acids, lipids and lipoproteins: Application to neurological disorders
Hamilton, J. A., Hillard, C. J., Spector, A. A. & Watkins, P. A., Sep 2007, In: Journal of Molecular Neuroscience. 33, 1, p. 2-11 10 p.Research output: Contribution to journal › Article › peer-review
54 Scopus citations -
Evidence for 26 distinct acyl-coenzyme A synthetase genes in the human genome
Watkins, P. A., Maiguel, D., Jia, Z. & Pevsner, J., Dec 2007, In: Journal of Lipid Research. 48, 12, p. 2736-2750 15 p.Research output: Contribution to journal › Article › peer-review
Open Access200 Scopus citations -
Fatty acid transport protein 4 is the principal very long chain fatty acyl-CoA synthetase in skin fibroblasts
Jia, Z., Moulson, C. L., Pei, Z., Miner, J. H. & Watkins, P. A., Jul 13 2007, In: Journal of Biological Chemistry. 282, 28, p. 20573-20583 11 p.Research output: Contribution to journal › Article › peer-review
Open Access82 Scopus citations -
Peroxisomal diseases
Watkins, P. A., Schwarz, K. B. & Schwarz, K. B., Jan 1 2007, Liver Disease in Children, Third Edition. Cambridge University Press, p. 840-857 18 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
3 Scopus citations -
Roundtable discussion of session 1: Mechanisms of lipid uptake and transport in the brain
Watkins, P. A. & Hamilton, J. A., Sep 2007, In: Journal of Molecular Neuroscience. 33, 1, p. 45-50 6 p.Research output: Contribution to journal › Article › peer-review
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Roundtable discussion of session 2: Lipoproteins and polyunsaturated fatty acids
Watkins, P. A. & Hamilton, J. A., Sep 1 2007, In: Journal of Molecular Neuroscience. 33, 1, p. 74-79 6 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Roundtable discussion of session 3: Eicosanoids in brain function
Watkins, P. A. & Hamilton, J. A., Sep 1 2007, In: Journal of Molecular Neuroscience. 33, 1, p. 100-104 5 p.Research output: Contribution to journal › Article › peer-review
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Roundtable discussion of session 4: Fatty acids and lipids in brain disorders
Watkins, P. A. & Hamilton, J. A., Sep 2007, In: Journal of Molecular Neuroscience. 33, 1, p. 120-124 5 p.Research output: Contribution to journal › Article › peer-review
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Synopses of posters presented at the international workshop on brain uptake and utilization of fatty acids, lipids, and lipoproteins: Application to neurological disorders
Katz, R. & Watkins, P. A., Sep 2007, In: Journal of Molecular Neuroscience. 33, 1, p. 125-128 4 p.Research output: Contribution to journal › Article › peer-review
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The fatty acid transport protein (FATP) family: Very long chain acyl-CoA synthetases or solute carriers?
Jia, Z., Pei, Z., Maiguel, D., Toomer, C. J. & Watkins, P. A., Sep 2007, In: Journal of Molecular Neuroscience. 33, 1, p. 25-31 7 p.Research output: Contribution to journal › Article › peer-review
52 Scopus citations -
The role of peroxisomal ABC transporters in the mouse adrenal gland: The loss of Abcd2 (ALDR), Not Abcd1 (ALD), causes oxidative damage
Lu, J. F., Barron-Casella, E., Deering, R., Heinzer, A. K., Moser, A. B., DeMesy Bentley, K. L., Wand, G. S., McGuinness, M. C., Pei, Z., Watkins, P. A., Pujol, A., Smith, K. D. & Powers, J. M., Mar 2007, In: Laboratory Investigation. 87, 3, p. 261-272 12 p.Research output: Contribution to journal › Article › peer-review
Open Access26 Scopus citations -
2006
Bromocriptine reduces steatosis in obese rodent models
Davis, L. M., Pei, Z., Trush, M. A., Cheskin, L. J., Contoreggi, C., McCullough, K., Watkins, P. A. & Moran, T. H., Sep 2006, In: Journal of Hepatology. 45, 3, p. 439-444 6 p.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
Cellular uptake of fatty acids driven by the ER-localized acyl-CoA synthetase FATP4
Milger, K., Herrmann, T., Becker, C., Gotthardt, D., Zickwolf, J., Ehehalt, R., Watkins, P. A., Stremmel, W. & Füllekrug, J., Nov 15 2006, In: Journal of cell science. 119, 22, p. 4678-4688 11 p.Research output: Contribution to journal › Article › peer-review
Open Access151 Scopus citations -
The second member of the human and murine "bubblegum" family is a testis- and brainstem-specific Acyl-CoA synthetase
Pei, Z., Jia, Z. & Watkins, P. A., Mar 10 2006, In: Journal of Biological Chemistry. 281, 10, p. 6632-6641 10 p.Research output: Contribution to journal › Article › peer-review
Open Access31 Scopus citations -
2005
Adreno-leukodystrophy: Oxidative stress of mice and men
Powers, J. M., Pei, Z., Heinzer, A. K., Deering, R., Moser, A. B., Moser, H. W., Watkins, P. A. & Smith, K. D., Dec 2005, In: Journal of neuropathology and experimental neurology. 64, 12, p. 1067-1079 13 p.Research output: Contribution to journal › Article › peer-review
Open Access98 Scopus citations -
Comparative biochemical studies of the murine fatty acid transport proteins (FATP) expressed in yeast
DiRusso, C. C., Li, H., Darwis, D., Watkins, P. A., Berger, J. & Black, P. N., Apr 29 2005, In: Journal of Biological Chemistry. 280, 17, p. 16829-16837 9 p.Research output: Contribution to journal › Article › peer-review
Open Access105 Scopus citations