Paul A Nyquist

Professor

19942019
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Research Output 1994 2019

2019

A genome-wide association study identifies genetic loci associated with specific lobar brain volumes

van der Lee, S. J., Knol, M. J., Chauhan, G., Satizabal, C. L., Smith, A. V., Hofer, E., Bis, J. C., Hibar, D. P., Hilal, S., van den Akker, E. B., Arfanakis, K., Bernard, M., Yanek, L. R., Amin, N., Crivello, F., Cheung, J. W., Harris, T. B., Saba, Y., Lopez, O. L., Li, S. & 42 others, van der Grond, J., Yu, L., Paus, T., Roshchupkin, G. V., Amouyel, P., Jahanshad, N., Taylor, K. D., Yang, Q., Mathias, R. A., Boehringer, S., Mazoyer, B., Rice, K., Cheng, C. Y., Maillard, P., van Heemst, D., Wong, T. Y., Niessen, W. J., Beiser, A. S., Beekman, M., Zhao, W., Nyquist, P. A., Chen, C., Launer, L. J., Psaty, B. M., Ikram, M. K., Vernooij, M. W., Schmidt, H., Pausova, Z., Becker, D. M., De Jager, P. L., Thompson, P. M., van Duijn, C. M., Bennett, D. A., Slagboom, P. E., Schmidt, R., Longstreth, W. T., Ikram, M. A., Seshadri, S., Debette, S., Gudnason, V., Adams, H. H. H. & DeCarli, C., Dec 1 2019, In : Communications Biology. 2, 1, 285.

Research output: Contribution to journalArticle

Open Access
Genetic Loci
Genome-Wide Association Study
Occipital Lobe
Brain
Genes

Biospecimens and Molecular and Cellular Biomarkers in Aneurysmal Subarachnoid Hemorrhage Studies: Common Data Elements and Standard Reporting Recommendations

the Unruptured Intracranial Aneurysms and SAH CDE Project Investigators, Jan 1 2019, In : Neurocritical care.

Research output: Contribution to journalArticle

Subarachnoid Hemorrhage
Biomarkers
Meta-Analysis
Guidelines
Practice Guidelines
Homeostasis
Blood Pressure
Oximetry
Arterial Pressure
Brain Diseases

Common Data Element for Unruptured Intracranial Aneurysm and Subarachnoid Hemorrhage: Recommendations from Assessments and Clinical Examination Workgroup/Subcommittee

the Unruptured Intracranial Aneurysms and SAH CDE Project Investigators, Jan 1 2019, In : Neurocritical care.

Research output: Contribution to journalArticle

Intracranial Aneurysm
Subarachnoid Hemorrhage
Meta-Analysis
National Institute of Neurological Disorders and Stroke
Glasgow Coma Scale

Common Data Elements for Radiological Imaging of Patients with Subarachnoid Hemorrhage: Proposal of a Multidisciplinary Research Group

the Unruptured Intracranial Aneurysms and SAH CDE Project Investigators, Jun 16 2019, In : Neurocritical care. 30, p. 60-78 19 p.

Research output: Contribution to journalArticle

Subarachnoid Hemorrhage
Angiography
Intracranial Aneurysm
Research
Meta-Analysis

Common Data Elements for Subarachnoid Hemorrhage and Unruptured Intracranial Aneurysms: Recommendations from the Working Group on Subject Characteristics

the Unruptured Cerebral Aneurysms and SAH CDE Project Investigators, Jun 16 2019, In : Neurocritical care. 30, p. 20-27 8 p.

Research output: Contribution to journalArticle

Intracranial Aneurysm
Subarachnoid Hemorrhage
National Institute of Neurological Disorders and Stroke
Common Data Elements
Practice Guidelines

Common Data Elements for Unruptured Intracranial Aneurysm and Subarachnoid Hemorrhage Clinical Research: Recommendations from the Working Group on Long-Term Therapies

the Unruptured Intracranial Aneurysm and SAH CDE Project Investigators, Jun 16 2019, In : Neurocritical care. 30, p. 79-86 8 p.

Research output: Contribution to journalArticle

Intracranial Aneurysm
Subarachnoid Hemorrhage
National Institute of Neurological Disorders and Stroke
Research
Therapeutics
Intracranial Aneurysm
Subarachnoid Hemorrhage
Research
National Institute of Neurological Disorders and Stroke
Brain Ischemia
National Institute of Neurological Disorders and Stroke
National Library of Medicine (U.S.)
Intracranial Aneurysm
Subarachnoid Hemorrhage
Research

Correction to: Standards for Neurologic Critical Care Units: A Statement for Healthcare Professionals from The Neurocritical Care Society (Neurocritical Care, (2018), 29, 2, (145-160), 10.1007/s12028-018-0601-1)

Moheet, A. M., Livesay, S. L., Abdelhak, T., Bleck, T. P., Human, T., Karanjia, N., Lamer-Rosen, A., Medow, J., Nyquist, P. A., Rosengart, A., Smith, W., Torbey, M. T. & Chang, C. W. J., Jan 1 2019, In : Neurocritical care.

Research output: Contribution to journalComment/debate

Open Access
Critical Care
Nervous System
Certification
Delivery of Health Care
Physicians

Definition and Prioritization of Data Elements for Cohort Studies and Clinical Trials on Patients with Unruptured Intracranial Aneurysms: Proposal of a Multidisciplinary Research Group

the Unruptured Aneurysms and SAH CDE Project Investigators, Jun 16 2019, In : Neurocritical care. 30, p. 87-101 15 p.

Research output: Contribution to journalArticle

Intracranial Aneurysm
Cohort Studies
Clinical Trials
Subarachnoid Hemorrhage
Research
Minimally Invasive Surgical Procedures
Cerebral Hemorrhage
Safety
Hemorrhage
Bacterial Infections

Genetic architecture of subcortical brain structures in 38,851 individuals

Satizabal, C. L., Adams, H. H. H., Hibar, D. P., White, C. C., Knol, M. J., Stein, J. L., Scholz, M., Sargurupremraj, M., Jahanshad, N., Roshchupkin, G. V., Smith, A. V., Bis, J. C., Jian, X., Luciano, M., Hofer, E., Teumer, A., van der Lee, S. J., Yang, J., Yanek, L. R., Lee, T. V. & 269 others, Li, S., Hu, Y., Koh, J. Y., Eicher, J. D., Desrivières, S., Arias-Vasquez, A., Chauhan, G., Athanasiu, L., Rentería, M. E., Kim, S., Hoehn, D., Armstrong, N. J., Chen, Q., Holmes, A. J., den Braber, A., Kloszewska, I., Andersson, M., Espeseth, T., Grimm, O., Abramovic, L., Alhusaini, S., Milaneschi, Y., Papmeyer, M., Axelsson, T., Ehrlich, S., Roiz-Santiañez, R., Kraemer, B., Håberg, A. K., Jones, H. J., Pike, G. B., Stein, D. J., Stevens, A., Bralten, J., Vernooij, M. W., Harris, T. B., Filippi, I., Witte, A. V., Guadalupe, T., Wittfeld, K., Mosley, T. H., Becker, J. T., Doan, N. T., Hagenaars, S. P., Saba, Y., Cuellar-Partida, G., Amin, N., Hilal, S., Nho, K., Mirza-Schreiber, N., Arfanakis, K., Becker, D. M., Ames, D., Goldman, A. L., Lee, P. H., Boomsma, D. I., Lovestone, S., Giddaluru, S., Le Hellard, S., Mattheisen, M., Bohlken, M. M., Kasperaviciute, D., Schmaal, L., Lawrie, S. M., Agartz, I., Walton, E., Tordesillas-Gutierrez, D., Davies, G. E., Shin, J., Ipser, J. C., Vinke, L. N., Hoogman, M., Jia, T., Burkhardt, R., Klein, M., Crivello, F., Janowitz, D., Carmichael, O., Haukvik, U. K., Aribisala, B. S., Schmidt, H., Strike, L. T., Cheng, C. Y., Risacher, S. L., Pütz, B., Fleischman, D. A., Assareh, A. A., Mattay, V. S., Buckner, R. L., Mecocci, P., Dale, A. M., Cichon, S., Boks, M. P., Matarin, M., Penninx, B. W. J. H., Calhoun, V. D., Chakravarty, M. M., Marquand, A. F., Macare, C., Kharabian Masouleh, S., Oosterlaan, J., Amouyel, P., Hegenscheid, K., Rotter, J. I., Schork, A. J., Liewald, D. C. M., de Zubicaray, G. I., Wong, T. Y., Shen, L., Sämann, P. G., Brodaty, H., Roffman, J. L., de Geus, E. J. C., Tsolaki, M., Erk, S., van Eijk, K. R., Cavalleri, G. L., van der Wee, N. J. A., McIntosh, A. M., Gollub, R. L., Bulayeva, K. B., Bernard, M., Richards, J. S., Himali, J. J., Loeffler, M., Rommelse, N., Hoffmann, W., Westlye, L. T., Valdés Hernández, M. C., Hansell, N. K., van Erp, T. G. M., Wolf, C., Kwok, J. B. J., Vellas, B., Heinz, A., Olde Loohuis, L. M., Delanty, N., Ho, B. C., Ching, C. R. K., Shumskaya, E., Singh, B., Hofman, A., van der Meer, D., Homuth, G., Psaty, B. M., Bastin, M. E., Montgomery, G. W., Foroud, T. M., Reppermund, S., Hottenga, J. J., Simmons, A., Meyer-Lindenberg, A., Cahn, W., Whelan, C. D., van Donkelaar, M. M. J., Yang, Q., Hosten, N., Green, R. C., Thalamuthu, A., Mohnke, S., Hulshoff Pol, H. E., Lin, H., Jack, C. R., Schofield, P. R., Mühleisen, T. W., Maillard, P., Potkin, S. G., Wen, W., Fletcher, E., Toga, A. W., Gruber, O., Huentelman, M., Davey Smith, G., Launer, L. J., Nyberg, L., Jönsson, E. G., Crespo-Facorro, B., Koen, N., Greve, D. N., Uitterlinden, A. G., Weinberger, D. R., Steen, V. M., Fedko, I. O., Groenewold, N. A., Niessen, W. J., Toro, R., Tzourio, C., Longstreth, W. T., Ikram, M. K., Smoller, J. W., van Tol, M. J., Sussmann, J. E., Paus, T., Lemaître, H., Schroeter, M. L., Mazoyer, B., Andreassen, O. A., Holsboer, F., Depondt, C., Veltman, D. J., Turner, J. A., Pausova, Z., Schumann, G., van Rooij, D., Djurovic, S., Deary, I. J., McMahon, K. L., Müller-Myhsok, B., Brouwer, R. M., Soininen, H., Pandolfo, M., Wassink, T. H., Cheung, J. W., Wolfers, T., Martinot, J. L., Zwiers, M. P., Nauck, M., Melle, I., Martin, N. G., Kanai, R., Westman, E., Kahn, R. S., Sisodiya, S. M., White, T., Saremi, A., van Bokhoven, H., Brunner, H. G., Völzke, H., Wright, M. J., van ‘t Ent, D., Nöthen, M. M., Ophoff, R. A., Buitelaar, J. K., Fernández, G., Sachdev, P. S., Rietschel, M., van Haren, N. E. M., Fisher, S. E., Beiser, A. S., Francks, C., Saykin, A. J., Mather, K. A., Romanczuk-Seiferth, N., Hartman, C. A., DeStefano, A. L., Heslenfeld, D. J., Weiner, M. W., Walter, H., Hoekstra, P. J., Nyquist, P. A., Franke, B., Bennett, D. A., Grabe, H. J., Johnson, A. D., Chen, C., van Duijn, C. M., Lopez, O. L., Fornage, M., Wardlaw, J. M., Schmidt, R., DeCarli, C., De Jager, P. L., Villringer, A., Debette, S., Gudnason, V., Medland, S. E., Shulman, J. M., Thompson, P. M., Seshadri, S. & Ikram, M. A., Nov 1 2019, In : Nature genetics. 51, 11, p. 1624-1636 13 p.

Research output: Contribution to journalArticle

Axonal Transport
Globus Pallidus
Caudate Nucleus
Genome-Wide Association Study
Putamen

Haptoglobin genotype and aneurysmal subarachnoid hemorrhage: Individual patient data analysis

Gaastra, B., Ren, D., Alexander, S., Bennett, E. R., Bielawski, D. M., Blackburn, S. L., Borsody, M. K., Doré, S., Galea, J., Garland, P., He, T., Iihara, K., Kawamura, Y., Leclerc, J. L., Meschia, J. F., Pizzi, M. A., Tamargo, R. J., Yang, W., Nyquist, P. A., Bulters, D. O. & 1 others, Galea, I., Apr 30 2019, In : Neurology. 92, 18, p. e2150-e2164

Research output: Contribution to journalArticle

Haptoglobins
Subarachnoid Hemorrhage
Genotype
Glasgow Outcome Scale
Neurologic Manifestations

Intensive Care Unit Readmission in patients with primary brain injury and tracheostomy

Pandian, V., Datta, M., Nakka, S., Tammineedi, D. S., Davidson, P. M. & Nyquist, P. A., Jan 1 2019, In : American Journal of Critical Care. 28, 1, p. 56-63 8 p.

Research output: Contribution to journalArticle

Patient Readmission
Tracheostomy
Brain Injuries
Intensive Care Units
Glasgow Coma Scale

Prioritization and Timing of Outcomes and Endpoints After Aneurysmal Subarachnoid Hemorrhage in Clinical Trials and Observational Studies: Proposal of a Multidisciplinary Research Group

the Unruptured Intracranial Aneurysms and SAH CDE Project Investigators, Jan 1 2019, In : Neurocritical care.

Research output: Contribution to journalArticle

Subarachnoid Hemorrhage
Observational Studies
Clinical Trials
Intracranial Aneurysm
Research

Remote ischemic preconditioning effects on brain vasculature

Nyquist, P. & Georgakis, M. K., Jul 2 2019, In : Neurology. 93, 1, p. 15-16 2 p.

Research output: Contribution to journalEditorial

Ischemic Preconditioning
Brain

The Future of Neurocritical Care Research: Proceedings and Recommendations from the Fifth Neurocritical Care Research Network Conference

the attendees of the 5th Neurocritical Care Research Network Conference, Jan 1 2019, (Accepted/In press) In : Neurocritical care.

Research output: Contribution to journalArticle

Research
Oceans and Seas
Telecommunications
2018
Cerebrovascular Circulation
Sepsis
Homeostasis
Blood Pressure
Guidelines

Exome Chip Analysis Identifies Low-Frequency and Rare Variants in MRPL38 for White Matter Hyperintensities on Brain Magnetic Resonance Imaging

neuroCHARGE Working Group, Aug 1 2018, In : Stroke. 49, 8, p. 1812-1819 8 p.

Research output: Contribution to journalArticle

Exome
Magnetic Resonance Imaging
Brain
Meta-Analysis
Cerebral Small Vessel Diseases

Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume

Vojinovic, D., Adams, H. H., Jian, X., Yang, Q., Smith, A. V., Bis, J. C., Teumer, A., Scholz, M., Armstrong, N. J., Hofer, E., Saba, Y., Luciano, M., Bernard, M., Trompet, S., Yang, J., Gillespie, N. A., van der Lee, S. J., Neumann, A., Ahmad, S., Andreassen, O. A. & 71 others, Ames, D., Amin, N., Arfanakis, K., Bastin, M. E., Becker, D. M., Beiser, A. S., Beyer, F., Brodaty, H., Bryan, R. N., Bülow, R., Dale, A. M., De Jager, P. L., Deary, I. J., DeCarli, C., Fleischman, D. A., Gottesman, R. F., van der Grond, J., Gudnason, V., Harris, T. B., Homuth, G., Knopman, D. S., Kwok, J. B., Lewis, C. E., Li, S., Loeffler, M., Lopez, O. L., Maillard, P., El Marroun, H., Mather, K. A., Mosley, T. H., Muetzel, R. L., Nauck, M., Nyquist, P. A., Panizzon, M. S., Pausova, Z., Psaty, B. M., Rice, K., Rotter, J. I., Royle, N., Satizabal, C. L., Schmidt, R., Schofield, P. R., Schreiner, P. J., Sidney, S., Stott, D. J., Thalamuthu, A., Uitterlinden, A. G., Valdés Hernández, M. C., Vernooij, M. W., Wen, W., White, T., Witte, A. V., Wittfeld, K., Wright, M. J., Yanek, L., Tiemeier, H., Kremen, W. S., Bennett, D. A., Jukema, J. W., Paus, T., Wardlaw, J. M., Schmidt, H., Sachdev, P. S., Villringer, A., Grabe, H. J., Longstreth, W. T., van Duijn, C. M., Launer, L. J., Seshadri, S., Ikram, M. A. & Fornage, M., Dec 1 2018, In : Nature Communications. 9, 1, 3945.

Research output: Contribution to journalArticle

genome
Lateral Ventricles
Genome-Wide Association Study
loci
brain

Haemoglobin scavenging in intracranial bleeding: Biology and clinical implications

Bulters, D., Gaastra, B., Zolnourian, A., Alexander, S., Ren, D., Blackburn, S. L., Borsody, M., Doré, S., Galea, J., Iihara, K., Nyquist, P. A. & Galea, I., Jul 1 2018, In : Nature Reviews Neurology. 14, 7, p. 416-432 17 p.

Research output: Contribution to journalReview article

Hemoglobins
Hemorrhage
Heme
Hemopexin
Heme Oxygenase (Decyclizing)
Anisotropy
Hypertension
Linear Models
Blood Pressure
Leukoencephalopathies

Sleep in Peace, and Wake in Joy

Nyquist, P., Jul 1 2018, In : Critical care medicine. 46, 7, p. 1193-1194 2 p.

Research output: Contribution to journalComment/debate

Indenes
Melatonin Receptors
Wakefulness
Intensive Care Units
Sleep

Standards for Neurologic Critical Care Units: A Statement for Healthcare Professionals from The Neurocritical Care Society

Moheet, A. M., Livesay, S. L., Abdelhak, T., Bleck, T. P., Human, T., Karanjia, N., Lamer-Rosen, A., Medow, J., Nyquist, P. A., Rosengart, A., Smith, W., Torbey, M. T. & Chang, C. W. J., Jan 1 2018, (Accepted/In press) In : Neurocritical Care.

Research output: Contribution to journalArticle

Critical Care
Nervous System
Committee Membership
Delivery of Health Care
Quality of Health Care

The present state of neurointensivist training in the United States: A comparison to other critical care training programs

Marcolini, E. G., Seder, D. B., Bonomo, J. B., Bleck, T. P., Claude Hemphill, J., Shutter, L., Rincon, F., Timmons, S. D. & Nyquist, P. A., Feb 1 2018, In : Critical Care Medicine. 46, 2, p. 307-315 9 p.

Research output: Contribution to journalArticle

Graduate Medical Education
Critical Care
Education
Nervous System
Program Development
2017

Genetics, white matter, and cognition: The effects of methylation on FMR1

Nyquist, P. A. & Hagerman, R., May 30 2017, In : Neurology. 88, 22, p. 2070-2071 2 p.

Research output: Contribution to journalEditorial

Cognition
Methylation
White Matter

Management of infections associated with neurocritical care

Rivera Lara, L., Ziai, W. C. & Nyquist, P. A., 2017, In : Handbook of Clinical Neurology. 140, p. 365-378 14 p.

Research output: Contribution to journalReview article

Cross Infection
Infection
Length of Stay
Neurosurgical Procedures
Hospital Costs

Novel genetic loci associated with hippocampal volume

Hibar, D. P., Adams, H. H. H., Jahanshad, N., Chauhan, G., Stein, J. L., Hofer, E., Renteria, M. E., Bis, J. C., Arias-Vasquez, A., Ikram, M. K., Desrivières, S., Vernooij, M. W., Abramovic, L., Alhusaini, S., Amin, N., Andersson, M., Arfanakis, K., Aribisala, B. S., Armstrong, N. J., Athanasiu, L. & 312 others, Axelsson, T., Beecham, A. H., Beiser, A., Bernard, M., Blanton, S. H., Bohlken, M. M., Boks, M. P., Bralten, J., Brickman, A. M., Carmichael, O., Chakravarty, M. M., Chen, Q., Ching, C. R. K., Chouraki, V., Cuellar-Partida, G., Crivello, F., Den Braber, A., Doan, N. T., Ehrlich, S., Giddaluru, S., Goldman, A. L., Gottesman, R. F., Grimm, O., Griswold, M. E., Guadalupe, T., Gutman, B. A., Hass, J., Haukvik, U. K., Hoehn, D., Holmes, A. J., Hoogman, M., Janowitz, D., Jia, T., Jørgensen, K. N., Karbalai, N., Kasperaviciute, D., Kim, S., Klein, M., Kraemer, B., Lee, P. H., Liewald, D. C. M., Lopez, L. M., Luciano, M., MacAre, C., Marquand, A. F., Matarin, M., Mather, K. A., Mattheisen, M., McKay, D. R., Milaneschi, Y., Muñoz Maniega, S., Nho, K., Nugent, A. C., Nyquist, P. A., Loohuis, L. M. O., Oosterlaan, J., Papmeyer, M., Pirpamer, L., Pütz, B., Ramasamy, A., Richards, J. S., Risacher, S. L., Roiz-Santiañez, R., Rommelse, N., Ropele, S., Rose, E. J., Royle, N. A., Rundek, T., Sämann, P. G., Saremi, A., Satizabal, C. L., Schmaal, L., Schork, A. J., Shen, L., Shin, J., Shumskaya, E., Smith, A. V., Sprooten, E., Strike, L. T., Teumer, A., Tordesillas-Gutierrez, D., Toro, R., Trabzuni, D., Trompet, S., Vaidya, D., Van Der Grond, J., Van Der Lee, S. J., Van Der Meer, D., Van Donkelaar, M. M. J., Van Eijk, K. R., Van Erp, T. G. M., Van Rooij, D., Walton, E., Westlye, L. T., Whelan, C. D., Windham, B. G., Winkler, A. M., Wittfeld, K., Woldehawariat, G., Wolf, C., Wolfers, T., Yanek, L., Yang, J., Zijdenbos, A., Zwiers, M. P., Agartz, I., Almasy, L., Ames, D., Amouyel, P., Andreassen, O. A., Arepalli, S., Assareh, A. A., Barral, S., Bastin, M. E., Becker, D. M., Becker, J. T., Bennett, D. A., Blangero, J., Van Bokhoven, H., Boomsma, D. I., Brodaty, H., Brouwer, R. M., Brunner, H. G., Buckner, R. L., Buitelaar, J. K., Bulayeva, K. B., Cahn, W., Calhoun, V. D., Cannon, D. M., Cavalleri, G. L., Cheng, C. Y., Cichon, S., Cookson, M. R., Corvin, A., Crespo-Facorro, B., Curran, J. E., Czisch, M., Dale, A. M., Davies, G. E., De Craen, A. J. M., De Geus, E. J. C., De Jager, P. L., De Zubicaray, G. I., Deary, I. J., Debette, S., Decarli, C., Delanty, N., Depondt, C., Destefano, A., Dillman, A., Djurovic, S., Donohoe, G., Drevets, W. C., Duggirala, R., Dyer, T. D., Enzinger, C., Erk, S., Espeseth, T., Fedko, I. O., Fernández, G., Ferrucci, L., Fisher, S. E., Fleischman, D. A., Ford, I., Fornage, M., Foroud, T. M., Fox, P. T., Francks, C., Fukunaga, M., Gibbs, J. R., Glahn, D. C., Gollub, R. L., Göring, H. H. H., Green, R. C., Gruber, O., Gudnason, V., Guelfi, S., Håberg, A. K., Hansell, N. K., Hardy, J., Hartman, C. A., Hashimoto, R., Hegenscheid, K., Heinz, A., Le Hellard, S., Hernandez, D. G., Heslenfeld, D. J., Ho, B. C., Hoekstra, P. J., Hoffmann, W., Hofman, A., Holsboer, F., Homuth, G., Hosten, N., Hottenga, J. J., Huentelman, M., Pol, H. E. H., Ikeda, M., Jack, C. R., Jenkinson, M., Johnson, R., Jönsson, E. G., Jukema, J. W., Kahn, R. S., Kanai, R., Kloszewska, I., Knopman, D. S., Kochunov, P., Kwok, J. B., Lawrie, S. M., Lemaître, H., Liu, X., Longo, D. L., Lopez, O. L., Lovestone, S., Martinez, O., Martinot, J. L., Mattay, V., McDonald, C., McIntosh, A. M., McMahon, F. J., McMahon, K. L., Mecocci, P., Melle, I., Meyer-Lindenberg, A., Mohnke, S., Montgomery, G. W., Morris, D. W., Mosley, T. H., Mühleisen, T. W., Müller-Myhsok, B., Nalls, M. A., Nauck, M., Nichols, T. E., Niessen, W. J., Nöthen, M. M., Nyberg, L., Ohi, K., Olvera, R. L., Ophoff, R. A., Pandolfo, M., Paus, T., Pausova, Z., Penninx, B. W. J. H., Pike, G. B., Potkin, S. G., Psaty, B. M., Reppermund, S., Rietschel, M., Roffman, J. L., Romanczuk-Seiferth, N., Rotter, J. I., Ryten, M., Sacco, R. L., Sachdev, P. S., Saykin, A. J., Schmidt, R., Schmidt, H., Schofield, P. R., Sigursson, S., Simmons, A., Singleton, A., Sisodiya, S. M., Smith, C., Smoller, J. W., Soininen, H., Steen, V. M., Stott, D. J., Sussmann, J. E., Thalamuthu, A., Toga, A. W., Traynor, B. J., Troncoso, J. C., Tsolaki, M., Tzourio, C., Uitterlinden, A. G., Hernández, M. C. V., Van Der Brug, M., Van Der Lugt, A., Van Der Wee, N. J. A., Van Haren, N. E. M., Van 'T Ent, D., Van Tol, M. J., Vardarajan, B. N., Vellas, B., Veltman, D. J., Völzke, H., Walter, H., Wardlaw, J. M., Wassink, T. H., Weale, M. E., Weinberger, D., Weiner, M. W., Wen, W., Westman, E., White, T., Wong, T. Y., Wright, C. B., Zielke, R. H., Zonderman, A. B., Martin, N. G., Van Duijn, C. M., Wright, M. J., Longstreth, W. T., Schumann, G., Grabe, H. J., Franke, B., Launer, L. J., Medland, S. E., Seshadri, S., Thompson, P. M. & Ikram, M. A., Jan 18 2017, In : Nature Communications. 8, 13624.

Research output: Contribution to journalArticle

Genetic Loci
loci
Hippocampus
Genes
Episodic Memory

Phase I/II multicenter ketogenic diet study for adult superrefractory status epilepticus

Cervenka, M., Hocker, S., Koenig, M., Bar, B., Henry-Barron, B., Kossoff, E. H., Hartman, A. L., Probasco, J. C., Benavides, D. R., Venkatesan, A., Hagen, E. C., Dittrich, D., Stern, T., Radzik, B., Depew, M., Caserta, F. M., Nyquist, P. A., Kaplan, P. W. & Geocadin, R., Mar 7 2017, In : Neurology. 88, 10, p. 938-943 6 p.

Research output: Contribution to journalArticle

Ketogenic Diet
Status Epilepticus
Ketosis
Safety
Ketone Bodies

Prophylaxis of Venous Thrombosis in Neurocritical Care Patients: An Executive Summary of Evidence-Based Guidelines: A Statement for Healthcare Professionals From the Neurocritical Care Society and Society of Critical Care Medicine

Nyquist, P. A., Jichici, D., Bautista, C., Burns, J., Chhangani, S., DeFilippis, M., Goldenberg, F. D., Kim, K., Liu-DeRyke, X., Mack, W. & Meyer, K., Jan 12 2017, (Accepted/In press) In : Critical Care Medicine.

Research output: Contribution to journalArticle

Venous Thrombosis
Patient Care
Guidelines
Delivery of Health Care
2016

Expertise Matters

Manno, E. M., Freeman, W. D., Livesay, S., Geocadin, R., Torbey, M., Nyquist, P. A. & Hemphill, C., Nov 1 2016, In : Critical Care Medicine. 44, 11, p. e1147-e1148

Research output: Contribution to journalLetter

Novel genetic loci underlying human intracranial volume identified through genome-wide association

Adams, H. H. H., Hibar, D. P., Chouraki, V., Stein, J. L., Nyquist, P. A., Rentería, M. E., Trompet, S., Arias-Vasquez, A., Seshadri, S., Desrivières, S., Beecham, A. H., Jahanshad, N., Wittfeld, K., van der Lee, S. J., Abramovic, L., Alhusaini, S., Amin, N., Andersson, M., Arfanakis, K., Aribisala, B. S. & 322 others, Armstrong, N. J., Athanasiu, L., Axelsson, T., Beiser, A., Bernard, M., Bis, J. C., Blanken, L. M. E., Blanton, S. H., Bohlken, M. M., Boks, M. P., Bralten, J., Brickman, A. M., Carmichael, O., Chakravarty, M. M., Chauhan, G., Chen, Q., Ching, C. R. K., Cuellar-Partida, G., Braber, A. D., Doan, N. T., Ehrlich, S., Filippi, I., Ge, T., Giddaluru, S., Goldman, A. L., Gottesman, R. F., Greven, C. U., Grimm, O., Griswold, M. E., Guadalupe, T., Hass, J., Haukvik, U. K., Hilal, S., Hofer, E., Hoehn, D., Holmes, A. J., Hoogman, M., Janowitz, D., Jia, T., Kasperaviciute, D., Kim, S., Klein, M., Kraemer, B., Lee, P. H., Liao, J., Liewald, D. C. M., Lopez, L. M., Luciano, M., Macare, C., Marquand, A., Matarin, M., Mather, K. A., Mattheisen, M., Mazoyer, B., McKay, D. R., McWhirter, R., Milaneschi, Y., Mirza-Schreiber, N., Muetzel, R. L., Maniega, S. M., Nho, K., Nugent, A. C., Loohuis, L. M. O., Oosterlaan, J., Papmeyer, M., Pappa, I., Pirpamer, L., Pudas, S., Pütz, B., Rajan, K. B., Ramasamy, A., Richards, J. S., Risacher, S. L., Roiz-Santiañez, R., Rommelse, N., Rose, E. J., Royle, N. A., Rundek, T., Sämann, P. G., Satizabal, C. L., Schmaal, L., Schork, A. J., Shen, L., Shin, J., Shumskaya, E., Smith, A. V., Sprooten, E., Strike, L. T., Teumer, A., Thomson, R., Tordesillas-Gutierrez, D., Toro, R., Trabzuni, D., Vaidya, D., van der Grond, J., van der Meer, D., van Donkelaar, M. M. J., van Eijk, K. R., van Erp, T. G. M., van Rooij, D., Walton, E., Westlye, L. T., Whelan, C. D., Windham, B. G., Winkler, A. M., Woldehawariat, G., Wolf, C., Wolfers, T., Xu, B., Yanek, L. R., Yang, J., Zijdenbos, A., Zwiers, M. P., Agartz, I., Aggarwal, N. T., Almasy, L., Ames, D., Amouyel, P., Andreassen, O. A., Arepalli, S., Assareh, A. A., Barral, S., Bastin, M. E., Becker, D. M., Becker, J. T., Bennett, D. A., Blangero, J., van Bokhoven, H., Boomsma, D. I., Brodaty, H., Brouwer, R. M., Brunner, H. G., Buckner, R. L., Buitelaar, J. K., Bulayeva, K. B., Cahn, W., Calhoun, V. D., Cannon, D. M., Cavalleri, G. L., Chen, C., Cheng, C. Y., Cichon, S., Cookson, M. R., Corvin, A., Crespo-Facorro, B., Curran, J. E., Czisch, M., Dale, A. M., Davies, G. E., de Geus, E. J. C., de Jager, P. L., de Zubicaray, G. I., Delanty, N., Depondt, C., DeStefano, A. L., Dillman, A., Djurovic, S., Donohoe, G., Drevets, W. C., Duggirala, R., Dyer, T. D., Erk, S., Espeseth, T., Evans, D. A., Fedko, I. O., Fernández, G., Ferrucci, L., Fisher, S. E., Fleischman, D. A., Ford, I., Foroud, T. M., Fox, P. T., Francks, C., Fukunaga, M., Gibbs, J. R., Glahn, D. C., Gollub, R. L., Göring, H. H. H., Grabe, H. J., Green, R. C., Gruber, O., Gudnason, V., Guelfi, S., Hansell, N. K., Hardy, J., Hartman, C. A., Hashimoto, R., Hegenscheid, K., Heinz, A., Le Hellard, S., Hernandez, D. G., Heslenfeld, D. J., Ho, B. C., Hoekstra, P. J., Hoffmann, W., Hofman, A., Holsboer, F., Homuth, G., Hosten, N., Hottenga, J. J., Pol, H. E. H., Ikeda, M., Ikram, M. K., Jr, C. R. J., Jenkinson, M., Johnson, R., Jönsson, E. G., Jukema, J. W., Kahn, R. S., Kanai, R., Kloszewska, I., Knopman, D. S., Kochunov, P., Kwok, J. B., Lawrie, S. M., Lemaître, H., Liu, X., Longo, D. L., Jr, W. T. L., Lopez, O. L., Lovestone, S., Martinez, O., Martinot, J. L., Mattay, V. S., McDonald, C., McIntosh, A. M., McMahon, K. L., McMahon, F. J., Mecocci, P., Melle, I., Meyer-Lindenberg, A., Mohnke, S., Montgomery, G. W., Morris, D. W., Mosley, T. H., Mühleisen, T. W., Müller-Myhsok, B., Nalls, M. A., Nauck, M., Nichols, T. E., Niessen, W. J., Nöthen, M. M., Nyberg, L., Ohi, K., Olvera, R. L., Ophoff, R. A., Pandolfo, M., Paus, T., Pausova, Z., Penninx, B. W. J. H., Pike, G. B., Potkin, S. G., Psaty, B. M., Reppermund, S., Rietschel, M., Roffman, J. L., Romanczuk-Seiferth, N., Rotter, J. I., Ryten, M., Sacco, R. L., Sachdev, P. S., Saykin, A. J., Schmidt, R., Schofield, P. R., Sigurdsson, S., Simmons, A., Singleton, A., Sisodiya, S. M., Smith, C., Smoller, J. W., Soininen, H., Srikanth, V., Steen, V. M., Stott, D. J., Sussmann, J. E., Thalamuthu, A., Tiemeier, H., Toga, A. W., Traynor, B. J., Troncoso, J., Turner, J. A., Tzourio, C., Uitterlinden, A. G., Hernández, M. C. V., van der Brug, M., van der Lugt, A., van der Wee, N. J. A., van Duijn, C. M., van Haren, N. E. M., van ′t Ent, D., van Tol, M. J., Vardarajan, B. N., Veltman, D. J., Vernooij, M. W., Völzke, H., Walter, H., Wardlaw, J. M., Wassink, T. H., Weale, M. E., Weinberger, D. R., Weiner, M. W., Wen, W., Westman, E., White, T., Wong, T. Y., Wright, C. B., Zielke, H. R., Zonderman, A. B., Deary, I. J., DeCarli, C., Schmidt, H., Martin, N. G., de Craen, A. J. M., Wright, M. J., Launer, L. J., Schumann, G., Fornage, M., Franke, B., Debette, S., Medland, S. E., Ikram, M. A. & Thompson, P. M., Oct 3 2016, (Accepted/In press) In : Nature Neuroscience.

Research output: Contribution to journalArticle

Genetic Loci
Genome
Genome-Wide Association Study
Phosphatidylinositol 3-Kinases
Cognition

Prophylaxis of Venous Thrombosis in Neurocritical Care Patients: An Evidence-Based Guideline: A Statement for Healthcare Professionals from the Neurocritical Care Society

Nyquist, P. A., Bautista, C., Jichici, D., Burns, J., Chhangani, S., DeFilippis, M., Goldenberg, F. D., Kim, K., Liu-DeRyke, X., Mack, W. & Meyer, K., Feb 1 2016, In : Neurocritical Care. 24, 1, p. 47-60 14 p.

Research output: Contribution to journalArticle

Venous Thromboembolism
Venous Thrombosis
Patient Care
Guidelines
Delivery of Health Care

Surgical Strategies for Spontaneous Intracerebral Hemorrhage

Ziai, W. C., Nyquist, P. A. & Hanley, D. F., Jun 1 2016, In : Seminars in Neurology. 36, 3, p. 261-268 8 p.

Research output: Contribution to journalArticle

Cerebral Hemorrhage
Hematoma
Decision Making
Clinical Trials
Blood Pressure

Surgical Strategies for Spontaneous Intracerebral Hemorrhage

Ziai, W. C., Carhuapoma, J., Nyquist, P. A. & Hanley, D. F., Dec 1 2016, In : Seminars in Neurology. 36, 6, p. 531-541 11 p.

Research output: Contribution to journalArticle

Cerebral Hemorrhage
Hematoma
Decision Making
Therapeutics
Clinical Trials
2015

Age differences in periventricular and deep white matter lesions

Nyquist, P. A., Bilgel, M., Gottesman, R. F., Yanek, L., Moy, T. F., Becker, L., Cuzzocreo, J. L., Prince, J. L., Wasserman, B. A., Yousem, D. M., Becker, D. M., Kral, B. G. & Vaidya, D., Apr 1 2015, In : Neurobiology of Aging. 36, 4, p. 1653-1658 6 p.

Research output: Contribution to journalArticle

Coronary Artery Disease
White Matter
African Americans
Stroke
Magnetic Resonance Imaging

Common genetic variants influence human subcortical brain structures

Hibar, D. P., Stein, J. L., Renteria, M. E., Arias-Vasquez, A., Desrivières, S., Jahanshad, N., Toro, R., Wittfeld, K., Abramovic, L., Andersson, M., Aribisala, B. S., Armstrong, N. J., Bernard, M., Bohlken, M. M., Boks, M. P., Bralten, J., Brown, A. A., Mallar Chakravarty, M., Chen, Q., Ching, C. R. K. & 267 others, Cuellar-Partida, G., Den Braber, A., Giddaluru, S., Goldman, A. L., Grimm, O., Guadalupe, T., Hass, J., Woldehawariat, G., Holmes, A. J., Hoogman, M., Janowitz, D., Jia, T., Kim, S., Klein, M., Kraemer, B., Lee, P. H., Olde Loohuis, L. M., Luciano, M., MacAre, C., Mather, K. A., Mattheisen, M., Milaneschi, Y., Nho, K., Papmeyer, M., Ramasamy, A., Risacher, S. L., Roiz-Santiañez, R., Rose, E. J., Salami, A., Sämann, P. G., Schmaal, L., Schork, A. J., Shin, J., Strike, L. T., Teumer, A., Van Donkelaar, M. M. J., Van Eijk, K. R., Walters, R. K., Westlye, L. T., Whelan, C. D., Winkler, A. M., Zwiers, M. P., Alhusaini, S., Athanasiu, L., Ehrlich, S., Hakobjan, M. M. H., Hartberg, C. B., Haukvik, U. K., Heister, A. J. G. A. M., Hoehn, D., Kasperaviciute, D., Liewald, D. C. M., Lopez, L. M., Makkinje, R. R. R., Matarin, M., Naber, M. A. M., Reese McKay, D., Needham, M., Nugent, A. C., Pütz, B., Royle, N. A., Shen, L., Sprooten, E., Trabzuni, D., Van Der Marel, S. S. L., Van Hulzen, K. J. E., Walton, E., Wolf, C., Almasy, L., Ames, D., Arepalli, S., Assareh, A. A., Bastin, M. E., Brodaty, H., Bulayeva, K. B., Carless, M. A., Cichon, S., Corvin, A., Curran, J. E., Czisch, M., De Zubicaray, G. I., Dillman, A., Duggirala, R., Dyer, T. D., Erk, S., Fedko, I. O., Ferrucci, L., Foroud, T. M., Fox, P. T., Fukunaga, M., Raphael Gibbs, J., Göring, H. H. H., Green, R. C., Guelfi, S., Hansell, N. K., Hartman, C. A., Hegenscheid, K., Heinz, A., Hernandez, D. G., Heslenfeld, D. J., Hoekstra, P. J., Holsboer, F., Homuth, G., Hottenga, J. J., Ikeda, M., Jack, C. R., Jenkinson, M., Johnson, R., Kanai, R., Keil, M., Kent, J. W., Kochunov, P., Kwok, J. B., Lawrie, S. M., Liu, X., Longo, D. L., McMahon, K. L., Meisenzahl, E., Melle, I., Mohnke, S., Montgomery, G. W., Mostert, J. C., Mühleisen, T. W., Nalls, M. A., Nichols, T. E., Nilsson, L. G., Nöthen, M. M., Ohi, K., Olvera, R. L., Perez-Iglesias, R., Bruce Pike, G., Potkin, S. G., Reinvang, I., Reppermund, S., Rietschel, M., Romanczuk-Seiferth, N., Rosen, G. D., Rujescu, D., Schnell, K., Schofield, P. R., Smith, C., Steen, V. M., Sussmann, J. E., Thalamuthu, A., Toga, A. W., Traynor, B. J., Troncoso, J. C., Turner, J. A., Valdés Hernández, M. C., Van 'T Ent, D., Van Der Brug, M., Van Der Wee, N. J. A., Van Tol, M. J., Veltman, D. J., Wassink, T. H., Westman, E., Zielke, R. H., Zonderman, A. B., Ashbrook, D. G., Hager, R., Lu, L., McMahon, F. J., Morris, D. W., Williams, R. W., Brunner, H. G., Buckner, R. L., Buitelaar, J. K., Cahn, W., Calhoun, V. D., Cavalleri, G. L., Crespo-Facorro, B., Dale, A. M., Davies, G. E., Delanty, N., Depondt, C., Djurovic, S., Drevets, W. C., Espeseth, T., Gollub, R. L., Ho, B. C., Hoffmann, W., Hosten, N., Kahn, R. S., Le Hellard, S., Meyer-Lindenberg, A., Müller-Myhsok, B., Nauck, M., Nyberg, L., Pandolfo, M., Penninx, B. W. J. H., Roffman, J. L., Sisodiya, S. M., Smoller, J. W., Van Bokhoven, H., Van Haren, N. E. M., Völzke, H., Walter, H., Weiner, M. W., Wen, W., White, T., Agartz, I., Andreassen, O. A., Blangero, J., Boomsma, D. I., Brouwer, R. M., Cannon, D. M., Cookson, M. R., De Geus, E. J. C., Deary, I. J., Donohoe, G., Fernández, G., Fisher, S. E., Francks, C., Glahn, D. C., Grabe, H. J., Gruber, O., Hardy, J., Hashimoto, R., Hulshoff Pol, H. E., Jönsson, E. G., Kloszewska, I., Lovestone, S., Mattay, V., Mecocci, P., McDonald, C., McIntosh, A. M., Ophoff, R. A., Paus, T., Pausova, Z., Ryten, M., Sachdev, P. S., Saykin, A. J., Simmons, A., Singleton, A., Soininen, H., Wardlaw, J. M., Weale, M. E., Weinberger, D., Adams, H. H. H., Launer, L. J., Seiler, S., Schmidt, R., Chauhan, G., Satizabal, C. L., Becker, J. T., Yanek, L., Van Der Lee, S. J., Ebling, M., Fischl, B., Longstreth, W. T., Greve, D., Schmidt, H., Nyquist, P. A., Vinke, L. N., Van Duijn, C. M., Xue, L., Mazoyer, B., Bis, J. C., Gudnason, V., Seshadri, S., Ikram, M. A., Martin, N. G., Wright, M. J., Schumann, G., Franke, B., Thompson, P. M. & Medland, S. E., Apr 9 2015, In : Nature. 520, 7546, p. 224-229 6 p.

Research output: Contribution to journalArticle

Putamen
Brain
Developmental Genes
Transport Vesicles
Caudate Nucleus

Diploic arteriovenous fistulas—classification and endovascular management

Rivera Lara, L., Gailloud, P. & Nyquist, P. A., Sep 17 2015, In : Acta Neurochirurgica. 157, 9, p. 1485-1488 4 p.

Research output: Contribution to journalArticle

Arteriovenous Fistula
Drainage
Meningeal Arteries
Occipital Lobe
Parietal Lobe

Effect of white matter lesions on manual dexterity in healthy middle-aged persons

Nyquist, P. A., Yanek, L., Bilgel, M., Cuzzocreo, J. L., Becker, L., Chevalier-Davis, K., Yousem, D. M., Prince, J. L., Kral, B. G., Vaidya, D. & Becker, D. M., May 12 2015, In : Neurology. 84, 19, p. 1920-1926 7 p.

Research output: Contribution to journalArticle

Sex Education
Vascular Diseases
Coronary Artery Disease
Brain
Cerebrovascular Disorders

Elevated relative risk of aneurysmal subarachnoid hemorrhage with colder weather in the mid-Atlantic region

Rivera Lara, L., Kowalski, R. G., Schneider, E. B., Tamargo, R. J. & Nyquist, P. A., Oct 1 2015, In : Journal of Clinical Neuroscience. 22, 10, p. 1582-1587 6 p., 6048.

Research output: Contribution to journalArticle

Mid-Atlantic Region
Weather
Subarachnoid Hemorrhage
Temperature
Incidence

Haptoglobin 2-2 genotype is associated with cerebral salt wasting syndrome in aneurysmal subarachnoid hemorrhage

Murthy, S. B., Caplan, J., Levy, A. P., Pradilla, G., Moradiya, Y., Schneider, E. B., Shalom, H., Ziai, W. C., Tamargo, R. J. & Nyquist, P. A., Sep 22 2015, In : Neurosurgery. 78, 1, p. 71-76 6 p.

Research output: Contribution to journalArticle

Wasting Syndrome
Haptoglobins
Subarachnoid Hemorrhage
Salts
Genotype

Presence of haptoglobin-2 allele is associated with worse functional outcomes after spontaneous intracerebral hemorrhage

Murthy, S. B., Levy, A. P., Duckworth, J., Schneider, E. B., Shalom, H., Hanley, D. F., Tamargo, R. J. & Nyquist, P. A., 2015, In : World Neurosurgery. 83, 4, p. 583-587 5 p.

Research output: Contribution to journalArticle

Haptoglobins
Cerebral Hemorrhage
Alleles
Phenotype
Mortality

Variability in Diagnosis and Treatment of Ventilator-Associated Pneumonia in Neurocritical Care Patients

Kalanuria, A. A., Fellerman, D., Nyquist, P. A., Geocadin, R., Kowalski, R. G., Nussenblatt, V., Rajarathinam, M. & Ziai, W. C., Aug 3 2015, In : Neurocritical Care. 23, 1, p. 44-53 10 p.

Research output: Contribution to journalArticle

Ventilator-Associated Pneumonia
Patient Care
Anti-Bacterial Agents
Sputum
Therapeutics
Ventriculostomy
Cerebral Hemorrhage
Intracranial Hemorrhages
Hemorrhage
Randomized Controlled Trials
2014

A novel ischemic stroke risk locus at 12q24.12 using a genome-wide association study appro

Heyer, G. L. & Nyquist, P. A., Aug 19 2014, In : Neurology. 83, 8, p. 672-673 2 p.

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 12
Genome-Wide Association Study
Genetic Predisposition to Disease
Brain Ischemia
Stroke
African Americans
Health
Cardiovascular Diseases
Software
Stroke

Toxicity with hyperoxia in brain injury Retrospection identifies unforeseen obstacles

Nyquist, P. A., Feb 2014, In : Critical Care Medicine. 42, 2, p. 469-470 2 p.

Research output: Contribution to journalArticle

Hyperoxia
Hospital Mortality
Brain Injuries
Stroke
2013

Automated anatomical labeling of the cerebral arteries using belief propagation

Bilgel, M., Roy, S., Carass, A., Nyquist, P. A. & Prince, J. L., 2013, Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8669. 866918

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Cerebral Arteries
arteries
Labeling
marking
vessels