Paul A Bottomley

Professor

1976 …2019
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Research Output 1976 2019

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19F magnetic resonance imaging

Holland, G. N., Bottomley, P. A. & Hinshaw, W. S., 1977, In : Journal of Magnetic Resonance (1969). 28, 1, p. 133-136 4 p.

Research output: Contribution to journalArticle

31P spectroscopic localization using pinwheel NMR excitation pulses

Hardy, C. J. & Bottomley, P. A., 1991, In : Magnetic Resonance in Medicine. 17, 2, p. 315-327 13 p.

Research output: Contribution to journalArticle

Pulse
Phosphorus

7 Tesla MRI with a transmit/receive loopless antenna and B 1-insensitive selective excitation

Erturk, M. A., El-Sharkawy, A. M. M., Moore, J. & Bottomley, P. A., 2014, In : Magnetic Resonance in Medicine. 72, 1, p. 220-226 7 p.

Research output: Contribution to journalArticle

Interventional Magnetic Resonance Imaging
Aorta
Rabbits
Signal-To-Noise Ratio
Heating

A broadband phased-array system for direct phosphorus and sodium metabolic MRI on a clinical scanner

Lee, R. F., Giaquinto, R., Constantinides, C., Souza, S., Weiss, R. G. & Bottomley, P. A., 2000, In : Magnetic Resonance in Medicine. 43, 2, p. 269-277 9 p.

Research output: Contribution to journalArticle

Signal-To-Noise Ratio
Phosphorus
Sodium
Protons
Magnetic Resonance Spectroscopy

Absolute temperature monitoring using RF radiometry in the MRI scanner

El-Sharkawy, A. M. M., Sotiriadis, P. P., Bottomley, P. A. & Atalar, E., Nov 2006, In : IEEE Transactions on Circuits and Systems I: Regular Papers. 53, 11, p. 2396-2404 9 p.

Research output: Contribution to journalArticle

Radiometry
Radiometers
Magnetic resonance
Imaging techniques
Monitoring

Accelerated spatially encoded spectroscopy of arbitrarily shaped compartments using prior knowledge and linear

Modeling, A., Bottomley, P. A. & Zhang, Y., 2015, In : eMagRes. 4, 1, p. 89-104 16 p.

Research output: Contribution to journalArticle

Signal-To-Noise Ratio
Spectrum Analysis
Signal to noise ratio
Spectroscopy
Magnetic Resonance Imaging

Acceleration and motion-correction techniques for high-resolution intravascular MRI

Hegde, S. S., Zhang, Y. & Bottomley, P. A., Aug 1 2015, In : Magnetic Resonance in Medicine. 74, 2, p. 452-461 10 p.

Research output: Contribution to journalArticle

Artifacts
Compensation and Redress
Costs and Cost Analysis
Signal-To-Noise Ratio
Endoscopy

A comparative evaluation of proton NMR imaging results

Bottomley, P. A., 1979, In : Journal of Magnetic Resonance (1969). 36, 1, p. 121-127 7 p.

Research output: Contribution to journalArticle

A computer driven photoscanner for medical imaging

Bottomley, P. A., Hinshaw, W. S. & Holland, G. N., 1978, In : Physics in Medicine and Biology. 23, 2, p. 309-317 9 p., 009.

Research output: Contribution to journalArticle

Medical imaging
Diagnostic Imaging
Color
Printed circuit boards
Light sources

A demonstration of the resolution of NMR imaging in biological systems

Hinshaw, W. S., Bottomley, P. A. & Holland, G. N., Sep 1979, In : Experientia. 35, 9, p. 1268-1269 2 p.

Research output: Contribution to journalArticle

Biological systems
Fruits
Protons
Fruit
Demonstrations

Advances in physiological chemistry by in vivo NMR: A workshop sponsored by the society of magnetic resonance held in Woods Hole, Massachusetts

Balaban, R., Bottomley, P. A., Brown, T. R., Gadian, D., Mountford, C., Radda, G. K., Ross, B. D., Shulman, R. G., Springer, C. & Ugurbil, K., 1995, In : Magnetic Resonance in Medicine. 34, 3, p. 289-292 4 p.

Research output: Contribution to journalArticle

AIDS dementia complex: Brain high-energy phosphate metabolite deficits

Bottomley, P. A., Hardy, C. J., Cousins, J. P., Armstrong, M. & Wagle, W. A., Aug 1990, In : Radiology. 176, 2, p. 407-411 5 p.

Research output: Contribution to journalArticle

AIDS Dementia Complex
Magnetic Resonance Spectroscopy
Phosphates
Phosphocreatine
Brain
Allopurinol
Adenosine
Creatine Kinase
Adenosine Triphosphate
Xanthine Oxidase

Altered creatine kinase adenosine triphosphate kinetics in failing hypertrophied human myocardium

Smith, C. S., Bottomley, P. A., Schulman, S. P., Gerstenblith, G. & Weiss, R. G., Sep 2006, In : Circulation. 114, 11, p. 1151-1158 8 p.

Research output: Contribution to journalArticle

Left Ventricular Hypertrophy
Creatine Kinase
Myocardium
Adenosine Triphosphate
Heart Failure

Altered myocardial high-energy phosphate metabolites in patients with dilated cardiomyopathy

Hardy, C. J., Weiss, R. G., Bottomley, P. A. & Gerstenblith, G., 1991, In : American Heart Journal. 122, 3 PART 1, p. 795-801 7 p.

Research output: Contribution to journalArticle

Dilated Cardiomyopathy
Phosphates
Adenosine Triphosphate
Phosphocreatine
Healthy Volunteers

Altered phosphate metabolism in myocardial infarction: P-31 MR spectroscopy

Bottomley, P. A., Herfkens, R. J., Smith, L. S. & Bashore, T. M., 1987, In : Radiology. 165, 3, p. 703-707 5 p.

Research output: Contribution to journalArticle

Magnetic Resonance Spectroscopy
Phosphates
Myocardial Infarction
Healthy Volunteers
2,3-Diphosphoglycerate

Alzheimer dementia: Quantification of energy metabolism and mobile phosphoesters with P-31 NMR spectroscopy

Bottomley, P. A., Cousins, J. P., Pendrey, D. L., Wagle, W. A., Hardy, C. J., Eames, F. A., McCaffrey, R. J. & Thompson, D. A., Jun 1992, In : Radiology. 183, 3, p. 695-699 5 p.

Research output: Contribution to journalArticle

Energy Metabolism
Alzheimer Disease
Magnetic Resonance Spectroscopy
Phosphates
Atrophy

A multichannel, real-time MRI RF power monitor for independent SAR determination

El-Sharkawy, A. M. M., Qian, D., Bottomley, P. A. & Edelstein, W. A., May 2012, In : Medical Physics. 39, 5, p. 2334-2341 8 p.

Research output: Contribution to journalArticle

Safety
Equipment and Supplies
Compliance
Volunteers
Magnetic Resonance Imaging

An analytical SMASH procedure (ASP) for sensitivity-encoded MRI

Lee, R. F., Westgate, C. R., Weiss, R. G. & Bottomley, P. A., 2000, In : Magnetic Resonance in Medicine. 43, 5, p. 716-725 10 p.

Research output: Contribution to journalArticle

Computer-Assisted Image Processing
Fourier Analysis
Magnetic Resonance Imaging

Anatomy and metabolism of the normal human brain studied by magnetic resonance at 1.5 Tesla

Bottomley, P. A., Hart, H. R., Edelstein, W. A., Schenck, J. F., Smith, L. S., Leue, W. M., Mueller, O. M. & Redington, R. W., 1984, In : Radiology. 150, 2, p. 441-446 6 p.

Research output: Contribution to journalArticle

Protons
Anatomy
Magnetic Resonance Spectroscopy
Head
Radio

An In Vivo Study of Phosphorus and Glucose Metabolism in Alzheimer's Disease using Magnetic Resonance Spectroscopy and PET

Murphy, D. G. M., Bottomley, P. A., Salerno, J. A., DeCarli, C., Mentis, M. J., Grady, C. L., Teichberg, D., Giacometti, K. R., Rosenberg, J. M., Hardy, C. J., Schapiro, M. B., Rapoport, S. I., Alger, J. R. & Horwitz, B., 1993, In : Archives of General Psychiatry. 50, 5, p. 341-349 9 p.

Research output: Contribution to journalArticle

Severity of Illness Index
Emission-Computed Tomography
Phosphorus
Alzheimer Disease
Magnetic Resonance Spectroscopy

An in vivo study of the fore-arm and hand by thin section NMR imaging

Hinshaw, W. S., Andrew, E. R., Bottomley, P. A., Holland, G. N., Moore, W. S. & Worthington, B. S., 1979, In : British Journal of Radiology. 52, 613, p. 36-43 8 p.

Research output: Contribution to journalArticle

Cadaver
Protons
Arm
Hand
Magnetic Resonance Imaging

An NMR phased array for human cardiac 31P spectroscopy

Hardy, C. J., Bottomley, P. A., Rohling, K. W. & Roemer, P. B., 1992, In : Magnetic Resonance in Medicine. 28, 1, p. 54-64 11 p.

Research output: Contribution to journalArticle

Signal-To-Noise Ratio
Spectrum Analysis
Myocardium

An RF dosimeter for independent SAR measurement in MRI scanners

Qian, D., El-Sharkawy, A. M. M., Bottomley, P. A. & Edelstein, W. A., Dec 2013, In : Medical Physics. 40, 12, 122303.

Research output: Contribution to journalArticle

Radio
Magnetic Resonance Imaging
Transducers
Torso
Safety

A proton magnetic resonance study of the motion of cage water molecules in the clathrate hydrate of xenon

Bottomley, P. A., Pope, J. M. & Cornell, B. A., 1976, In : Molecular Physics. 31, 4, p. 1277-1281 5 p.

Research output: Contribution to journalArticle

Xenon
proton magnetic resonance
clathrates
hydrates
xenon

A prototype RF dosimeter for independent measurement of the average specific absorption rate (SAR) during MRI

Stralka, J. P. & Bottomley, P. A., Nov 2007, In : Journal of Magnetic Resonance Imaging. 26, 5, p. 1296-1302 7 p.

Research output: Contribution to journalArticle

Transducers
Radio
Head
Torso
Calibration

A review of 1H nuclear magnetic resonance relaxation in pathology: Are T1 and T2 diagnostic?

Bottomley, P. A., Hardy, C. J., Argersinger, R. E. & Allen-Moore, G., 1987, In : Medical Physics. 14, 1, p. 1-37 37 p.

Research output: Contribution to journalArticle

Magnetic Resonance Spectroscopy
Pathology
Neoplasms
Liver
Temperature
Hydrogen
Magnetic Resonance Spectroscopy
Temperature
Water
Information Storage and Retrieval

A signal to noise calibration procedure for NMR imaging systems

Edelstein, W. A., Bottomley, P. A. & Pfeifer, L. M., 1984, In : Medical Physics. 11, 2, p. 180-185 6 p.

Research output: Contribution to journalArticle

Signal-To-Noise Ratio
Calibration
Noise
Magnetic Resonance Spectroscopy
Magnetic Resonance Imaging

Assessment of pharmacological treatment of myocardial infarction by phosphorus-31 NMR with surface coils

Nunnally, R. L. & Bottomley, P. A., 1981, In : Science. 211, 4478, p. 177-180 4 p.

Research output: Contribution to journalArticle

Phosphorus
Magnetic Resonance Spectroscopy
Myocardial Infarction
Pharmacology
Pharmaceutical Preparations
Impedance
Permittivity
frequency ranges
impedance
permittivity
Creatine Kinase
Adenosine Triphosphate
Heart Failure
Magnetic Resonance Spectroscopy
MB Form Creatine Kinase

Attenuated myocardial vasodilator response in patients with hypertensive hypertrophy revealed by oxygenation-dependent magnetic resonance imaging

Beache, G. M., Herzka, D., Boxerman, J. L., Post, W. S., Gupta, S. N., Faranesh, A. Z., Solaiyappan, M., Bottomley, P. A., Weiss, J. L., Shapiro, E. & Hill, M., Sep 11 2001, In : Circulation. 104, 11, p. 1214-1217 4 p.

Research output: Contribution to journalArticle

Vasodilator Agents
Hypertrophy
Magnetic Resonance Imaging
Ventricular Dysfunction
Dipyridamole

A versatile magnetic field gradient control system for NMR imaging

Bottomley, P. A., Sep 1981, In : Journal of Physics E: Scientific Instruments. 14, 9, p. 1081-1087 7 p.

Research output: Contribution to journalArticle

Gradient System
Spectrometers
Magnetic Field
Control System
Imaging

BIRP, an Improved Implementation of Low-Angle Adiabatic (BIR-4) Excitation Pulses

Bottomley, P. A. & Ouwerkerk, R., Jun 15 1993, In : Journal of Magnetic Resonance, Series A. 103, 2, p. 242-244 3 p.

Research output: Contribution to journalArticle

Creatine Kinase
Magnetic Resonance Spectroscopy
Heart Failure
Adenosine Triphosphate
Healthy Volunteers

Cardiovascular MRI probes for the outside in and for the inside out

Bottomley, P. A., Atalar, E., Lee, R. F., Shunk, K. A. & Lardo, A., 2000, In : Magma (New York, N.Y.). 11, 1-2, p. 49-51 3 p.

Research output: Contribution to journalArticle

Imaging Phantoms
Cardiovascular System
Magnetic Resonance Imaging

Categorical Course - The Bleeding Edge of Medical Innovation: Tools for the 21st Century

Antonuk, L., Naughton, G. K., Bottomley, P. A., Aralar, E., Halperin, H. R., Lardo, A., Foo, T., Yang, X., Johnson, M. S. & Warren, W. L., Feb 2000, In : Journal of Vascular and Interventional Radiology. 11, 2 II, p. 347-351 5 p.

Research output: Contribution to journalArticle

Cerebral energy metabolism in rats studied by phosphorus nuclear magnetic resonance using surface coils

Bottomley, P. A., Kogure, K., Namon, R. & Alonso, O. F., 1982, In : Magnetic Resonance Imaging. 1, 2, p. 81-85 5 p.

Research output: Contribution to journalArticle

metabolism
Metabolism
Phosphorus
Energy Metabolism
rats

Cerebral magnetic resonance: Comparison of high and low field strength imaging

Bilaniuk, L. T., Zimmerman, R. A., Wehrli, F. W., Goldberg, H. I., Grossman, R. I., Bottomley, P. A., Edelstein, W. A., Glover, G. H., MacFall, J. R. & Redington, R. W., 1984, In : Radiology. 153, 2, p. 409-414 6 p.

Research output: Contribution to journalArticle

Magnetic Fields
Magnetic Resonance Spectroscopy
Signal-To-Noise Ratio
Noise
Healthy Volunteers

Cerebral NMR: diagnostic evaluation of brain tumors by partial saturation technique with resistive NMR

Zimmerman, R. A., Bilaniuk, L. T., Grossman, R. I., Goldberg, H. I., Edelstein, W., Bottomley, P. A. & Redington, R. W., Jan 1985, In : Neuroradiology. 27, 1, p. 9-15 7 p.

Research output: Contribution to journalArticle

Brain Neoplasms
Edema
Neoplasms
Protons
Magnetic Resonance Imaging

Chemical exchange saturation transfer (CEST) imaging with fast variably-accelerated sensitivity encoding (vSENSE)

Zhang, Y., Heo, H. Y., Lee, D. H., Jiang, S., Zhao, X., Bottomley, P. A. & Zhou, J., 2016, (Accepted/In press) In : Magnetic Resonance in Medicine.

Research output: Contribution to journalArticle

Amides
Brain Neoplasms
Artifacts
Protons
Healthy Volunteers

CHEMICAL IMAGING OF THE BRAIN BY NMR

Bottomley, P. A., Foster, T. H. & Leue, W. M., May 19 1984, In : The Lancet. 323, 8386, p. 1120 1 p.

Research output: Contribution to journalArticle

Hydrogen
Magnetic Resonance Spectroscopy
Magnetic Resonance Imaging
Brain

Chronic adult cerebral infarction studied by phosphorus NMR spectroscopy

Bottomley, P. A., Drayer, B. P. & Smith, L. S., 1986, In : Radiology. 160, 3, p. 763-766 4 p.

Research output: Contribution to journalArticle

Cerebral Infarction
Phosphorus
Magnetic Resonance Spectroscopy
Phosphates
Brain Infarction

COLOUR DISPLAY TECHNIQUE FOR NMR IMAGING.

Holland, G. N. & Bottomley, P. A., Jul 1977, In : Journal of Physics E: Scientific Instruments. 10, 7, p. 714-716 3 p.

Research output: Contribution to journalArticle

Display
Display devices
Imaging
Color
color

Correcting for nonuniform k-space sampling in two-dimensional NMR selective excitation

Hardy, C. J., Cline, H. E. & Bottomley, P. A., 1990, In : Journal of Magnetic Resonance (1969). 87, 3, p. 639-645 7 p.

Research output: Contribution to journalArticle

Creatine
Adenosine Triphosphate
Thorax
Myocardium
Muscles

Correcting reaction rates measured by saturation-transfer magnetic resonance spectroscopy

Gabr, R. E., Weiss, R. G. & Bottomley, P. A., Apr 2008, In : Journal of Magnetic Resonance. 191, 2, p. 248-258 11 p.

Research output: Contribution to journalArticle

Magnetic resonance spectroscopy
magnetic resonance spectroscopy
Creatine Kinase
Reaction rates
reaction kinetics

Creatine kinase adenosine triphosphate and phosphocreatine energy supply in a single kindred of patients with hypertrophic cardiomyopathy

Abraham, M. R., Bottomley, P. A., Dimaano, V. L., Pinheiro, A., Steinberg, A., Traill, T. A., Abraham, T. P. & Weiss, R. G., Sep 15 2013, In : The American Journal of Cardiology. 112, 6, p. 861-866 6 p.

Research output: Contribution to journalArticle

Phosphocreatine
Hypertrophic Cardiomyopathy
Creatine Kinase
Adenosine Triphosphate
Mutation

Deconvolution-interpolation gridding (DING): Accurate reconstruction for arbitrary k-space trajectories

Gabr, R. E., Aksit, P., Bottomley, P. A., Youssef, A. B. M. & Kadah, Y. M., Dec 2006, In : Magnetic Resonance in Medicine. 56, 6, p. 1182-1191 10 p.

Research output: Contribution to journalArticle

Compensation and Redress
Computer Simulation
Costs and Cost Analysis