Patrick Cahan

Assistant Professor

20012018
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Hematopoietic Stem Cells Medicine & Life Sciences
Gene Regulatory Networks Medicine & Life Sciences
Epigenomics Medicine & Life Sciences
Genome Medicine & Life Sciences

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Research Output 2001 2018

A CLK3-HMGA2 Alternative Splicing Axis Impacts Human Hematopoietic Stem Cell Molecular Identity throughout Development

Cesana, M. , Guo, M. H. , Cacchiarelli, D. , Wahlster, L. , Barragan, J. , Doulatov, S. , Vo, L. T. , Salvatori, B. , Trapnell, C. , Clement, K. , Cahan, P. , Tsanov, K. M. , Sousa, P. M. , Tazon-Vega, B. , Bolondi, A. , Giorgi, F. M. , Califano, A. , Rinn, J. L. , Meissner, A. , Hirschhorn, J. N. & 1 others Daley, G. Q., Apr 5 2018, In : Cell Stem Cell. 22, 4, p. 575-588.e7

Research output: Contribution to journalArticle

Alternative Splicing
Hematopoietic Stem Cells
MicroRNAs
Long Noncoding RNA
Transcriptome

A single cell transcriptional portrait of embryoid body differentiation and comparison to progenitors of the developing embryo

Spangler, A., Su, E. Y., Craft, A. M. & Cahan, P., Aug 1 2018, In : Stem Cell Research. 31, p. 201-215 15 p.

Research output: Contribution to journalArticle

Embryoid Bodies
Embryonic Structures
Population
Primitive Streak
RNA

Programming Morphogenesis through Systems and Synthetic Biology

Velazquez, J. J., Su, E., Cahan, P. & Ebrahimkhani, M. R., Apr 1 2018, In : Trends in Biotechnology. 36, 4, p. 415-429 15 p.

Research output: Contribution to journalReview article

Synthetic Biology
Systems Biology
Gene Regulatory Networks
Stem cells
Morphogenesis

Assessment of engineered cells using CellNet and RNA-seq

Radley, A. H., Schwab, R. M., Tan, Y., Kim, J., Lo, E. K. W. & Cahan, P., May 1 2017, In : Nature Protocols. 12, 5, p. 1089-1102 14 p.

Research output: Contribution to journalArticle

RNA
Tissue
Cell engineering
Microarrays
Cell Engineering

Understanding development and stem cells using single cell-based analyses of gene expression

Kumar, P., Tan, Y. & Cahan, P., Jan 1 2017, In : Development (Cambridge). 144, 1, p. 17-32 16 p.

Research output: Contribution to journalReview article

Single-Cell Analysis
Stem Cells
Gene Expression
Cataloging
Genome